Abstract: The study of proteomics reached unexpected levels of
interest, as a direct consequence of its discovered influence over some
complex biological phenomena, such as problematic diseases like
cancer. This paper presents the latest authors- achievements regarding
the analysis of the networks of proteins (interactome networks), by
computing more efficiently the betweenness centrality measure. The
paper introduces the concept of betweenness centrality, and then
describes how betweenness computation can help the interactome net-
work analysis. Current sequential implementations for the between-
ness computation do not perform satisfactory in terms of execution
times. The paper-s main contribution is centered towards introducing
a speedup technique for the betweenness computation, based on
modified shortest path algorithms for sparse graphs. Three optimized
generic algorithms for betweenness computation are described and
implemented, and their performance tested against real biological
data, which is part of the IntAct dataset.
Abstract: UK breweries generate extensive by products in the
form of spent grain, slurry and yeast. Much of the spent grain is
produced by large breweries and processed in bulk for animal feed.
Spent brewery grains contain up to 20% protein dry weight and up to
60% fiber and are useful additions to animal feed. Bulk processing is
economic and allows spent grain to be sold so providing an income
to the brewery. A proportion of spent grain, however, is produced by
small local breweries and is more variably distributed to farms or
other users using intermittent collection methods. Such use is much
less economic and may incur losses if not carefully assessed for
transport costs. This study reports an economic returns of using wet
brewery spent grain (WBSG) in animal feed using the Co-product
Optimizer Decision Evaluator model (Cattle CODE) developed by
the University of Nebraska to predict performance and economic
returns when byproducts are fed to finishing cattle. The results
indicated that distance from brewery to farm had a significantly
greater effect on the economics of use of small brewery spent grain
and that alternative uses than cattle feed may be important to
develop.
Abstract: We prove detailed analysis of a waveguide-based Schottky barrier photodetector (SBPD) where a thin silicide film is put on the top of a silicon-on-insulator (SOI) channel waveguide to absorb light propagating along the waveguide. Taking both the confinement factor of light absorption and the wall scanning induced gain of the photoexcited carriers into account, an optimized silicide thickness is extracted to maximize the effective gain, thereby the responsivity. For typical lengths of the thin silicide film (10-20 Ðçm), the optimized thickness is estimated to be in the range of 1-2 nm, and only about 50-80% light power is absorbed to reach the maximum responsivity. Resonant waveguide-based SBPDs are proposed, which consist of a microloop, microdisc, or microring waveguide structure to allow light multiply propagating along the circular Si waveguide beneath the thin silicide film. Simulation results suggest that such resonant waveguide-based SBPDs have much higher repsonsivity at the resonant wavelengths as compared to the straight waveguidebased detectors. Some experimental results about Si waveguide-based SBPD are also reported.
Abstract: In the present study, the effect of ferrous sulfate concentration and total solids on bioleaching of heavy metals from sewage sludge has been examined using indigenous iron-oxidizing microorganisms. The experiments on effects of ferrous sulfate concentrations on bioleaching were carried out using ferrous sulfate of different concentrations (5-20 g L-1) to optimize the concentration of ferrous sulfate for maximum bioleaching. A rapid change in the pH and ORP took place in first 2 days followed by a slow change till 16th day in all the sludge samples. A 10 g L-1 ferrous sulfate concentration was found to be sufficient in metal bioleaching in the following order: Zn: 69%>Cu: 52%>Cr: 46%>Ni: 45. Further, bioleaching using 10 g/L ferrous sulfate was found to be efficient up to 20 g L-1 sludge solids concentration. The results of the present study strongly indicate that using 10 g L-1 ferrous sulfate indigenous iron-oxidizing microorganisms can bring down pH to a value needed for significant metal solubilization.
Abstract: Starting from a biologically inspired framework, Gabor filters were built up from retinal filters via LMSE algorithms. Asubset of retinal filter kernels was chosen to form a particular Gabor filter by using a weighted sum. One-dimensional optimization approaches were shown to be inappropriate for the problem. All model parameters were fixed with biological or image processing constraints. Detailed analysis of the optimization procedure led to the introduction of a minimization constraint. Finally, quantization of weighting factors was investigated. This resulted in an optimized cascaded structure of a Gabor filter bank implementation with lower computational cost.
Abstract: This paper presents a study of the Taguchi design
application to optimize surface quality in damper inserted end milling
operation. Maintaining good surface quality usually involves
additional manufacturing cost or loss of productivity. The Taguchi
design is an efficient and effective experimental method in which a
response variable can be optimized, given various factors, using
fewer resources than a factorial design. This Study included spindle
speed, feed rate, and depth of cut as control factors, usage of different
tools in the same specification, which introduced tool condition and
dimensional variability. An orthogonal array of L9(3^4)was used;
ANOVA analyses were carried out to identify the significant factors
affecting surface roughness, and the optimal cutting combination was
determined by seeking the best surface roughness (response) and
signal-to-noise ratio. Finally, confirmation tests verified that the
Taguchi design was successful in optimizing milling parameters for
surface roughness.
Abstract: Hidden Markov Model (HMM) is a stochastic method
which has been used in various signal processing and character
recognition. This study proposes to use HMM to recognize Javanese
characters from a number of different handwritings, whereby HMM
is used to optimize the number of state and feature extraction. An
85.7 % accuracy is obtained as the best result in 16-stated vertical
model using pure HMM. This initial result is satisfactory for
prompting further research.
Abstract: Rambutan is a tropical fruit which peel possesses antioxidant properties. This work was conducted to optimize extraction conditions of phenolic compounds from rambutan peel. Response surface methodology (RSM) was adopted to optimize subcritical water extraction (SWE) on temperature, extraction time and percent solvent mixture. The results demonstrated that the optimum conditions for SWE were as follows: temperature 160°C, extraction time 20min. and concentration of 50% ethanol. Comparison of the phenolic compounds from the rambutan peels in maceration 6h, soxhlet 4h, and SWE 20min., it indicated that total phenolic content (using Folin-Ciocalteu-s phenol reagent) was 26.42, 70.29, and 172.47mg of tannic acid equivalent (TAE) per g dry rambutan peel, respectively. The comparative study concluded that SWE was a promising technique for phenolic compounds extraction from rambutan peel, due to much more two times of conventional techniques and shorter extraction times.
Abstract: The System Identification problem looks for a
suitably parameterized model, representing a given process. The
parameters of the model are adjusted to optimize a performance
function based on error between the given process output and
identified process output. The linear system identification field is
well established with many classical approaches whereas most of
those methods cannot be applied for nonlinear systems. The problem
becomes tougher if the system is completely unknown with only the
output time series is available. It has been reported that the
capability of Artificial Neural Network to approximate all linear and
nonlinear input-output maps makes it predominantly suitable for the
identification of nonlinear systems, where only the output time series
is available. [1][2][4][5]. The work reported here is an attempt to
implement few of the well known algorithms in the context of
modeling of nonlinear systems, and to make a performance
comparison to establish the relative merits and demerits.
Abstract: Task of object localization is one of the major
challenges in creating intelligent transportation. Unfortunately, in
densely built-up urban areas, localization based on GPS only
produces a large error, or simply becomes impossible. New
opportunities arise for the localization due to the rapidly emerging
concept of a wireless ad-hoc network. Such network, allows
estimating potential distance between these objects measuring
received signal level and construct a graph of distances in which
nodes are the localization objects, and edges - estimates of the
distances between pairs of nodes. Due to the known coordinates of
individual nodes (anchors), it is possible to determine the location of
all (or part) of the remaining nodes of the graph. Moreover, road
map, available in digital format can provide localization routines
with valuable additional information to narrow node location search.
However, despite abundance of well-known algorithms for solving
the problem of localization and significant research efforts, there are
still many issues that currently are addressed only partially. In this
paper, we propose localization approach based on the graph mapped
distances on the digital road map data basis. In fact, problem is
reduced to distance graph embedding into the graph representing area
geo location data. It makes possible to localize objects, in some cases
even if only one reference point is available. We propose simple
embedding algorithm and sample implementation as spatial queries
over sensor network data stored in spatial database, allowing
employing effectively spatial indexing, optimized spatial search
routines and geometry functions.
Abstract: Topology Optimization is a defined as the method of
determining optimal distribution of material for the assumed design
space with functionality, loads and boundary conditions [1].
Topology optimization can be used to optimize shape for the
purposes of weight reduction, minimizing material requirements or
selecting cost effective materials [2]. Topology optimization has been
implemented through the use of finite element methods for the
analysis, and optimization techniques based on the method of moving
asymptotes, genetic algorithms, optimality criteria method, level sets
and topological derivatives. Case study of Typical “Fuselage design"
is considered for this paper to explain the benefits of Topology
Optimization in the design cycle. A cylindrical shell is assumed as
the design space and aerospace standard pay loads were applied on
the fuselage with wing attachments as constraints. Then topological
optimization is done using Finite Element (FE) based software. This
optimization results in the structural concept design which satisfies
all the design constraints using minimum material.
Abstract: Size based filtration is one of the common methods
employed to isolate circulating tumor cells (CTCs) from whole
blood. It is well known that this method suffers from isolation
efficiency to purity tradeoff. However, this tradeoff is poorly
understood. In this paper, we present the design and manufacturing
of a special rectangular slit filter. The filter was designed to retain
maximal amounts of nucleated cells, while minimizing the pressure
on cells, thereby preserving their morphology. The key parameter,
namely, input pressure, was optimized to retain the maximal number
of tumor cells, whilst maximizing the depletion of normal blood cells
(red and white blood cells and platelets). Our results indicate that for
a slit geometry of 5 × 40 μm on a 13 mm circular membrane with a
fill factor of 21%, a pressure of 6.9 mBar yields the optimum for
maximizing isolation of MCF-7 and depletion of normal blood cells.
Abstract: Everyday the usages of the Internet increase and simply a world of the data become accessible. Network providers do not want to let the provided services to be used in harmful or terrorist affairs, so they used a variety of methods to protect the special regions from the harmful data. One of the most important methods is supposed to be the firewall. Firewall stops the transfer of such packets through several ways, but in some cases they do not use firewall because of its blind packet stopping, high process power needed and expensive prices. Here we have proposed a method to find a discriminate function to distinguish between usual packets and harmful ones by the statistical processing on the network router logs. So an administrator can alarm to the user. This method is very fast and can be used simply in adjacent with the Internet routers.
Abstract: This paper presents a genetic algorithm based
approach for solving security constrained optimal power flow
problem (SCOPF) including FACTS devices. The optimal location of
FACTS devices are identified using an index called overload index
and the optimal values are obtained using an enhanced genetic
algorithm. The optimal allocation by the proposed method optimizes
the investment, taking into account its effects on security in terms of
the alleviation of line overloads. The proposed approach has been
tested on IEEE-30 bus system to show the effectiveness of the
proposed algorithm for solving the SCOPF problem.
Abstract: Automotive engine air-ratio plays an important role of
emissions and fuel consumption reduction while maintains
satisfactory engine power among all of the engine control variables. In
order to effectively control the air-ratio, this paper presents a model
predictive fuzzy control algorithm based on online least-squares
support vector machines prediction model and fuzzy logic optimizer.
The proposed control algorithm was also implemented on a real car for
testing and the results are highly satisfactory. Experimental results
show that the proposed control algorithm can regulate the engine
air-ratio to the stoichiometric value, 1.0, under external disturbance
with less than 5% tolerance.
Abstract: The objective of this research is parameters optimized
of the stair shape workpiece which is cut by CNC Wire-Cut EDM
(WEDW). The experiment material is SKD-11 steel of stair-shaped
with variable height workpiece 10, 20, 30 and 40 mm. with the same
10 mm. thickness are cut by Sodick's CNC Wire-Cut EDM model
AD325L.
The experiments are designed by 3k full factorial experimental
design at 3 level 2 factors and 9 experiments with 2 replicate. The
selected two factor are servo voltage (SV) and servo feed rate (SF)
and the response is cutting thickness error. The experiment is divided
in two experiments. The first experiment determines the significant
effective factor at confidential interval 95%. The SV factor is the
significant effective factor from first result. In order to result smallest
cutting thickness error of workpieces is 17 micron with the SV value
is 46 volt. Also show that the lower SV value, the smaller different
thickness error of workpiece. Then the second experiment is done to
reduce different cutting thickness error of workpiece as small as
possible by lower SV. The second experiment result show the
significant effective factor at confidential interval 95% is the SV
factor and the smallest cutting thickness error of workpieces reduce
to 11 micron with the experiment SV value is 36 volt.
Abstract: Response surface methodology was used for
quantitative investigation of water and solids transfer during osmotic
dehydration of beetroot in aqueous solution of salt. Effects of
temperature (25 – 45oC), processing time (30–150 min), salt
concentration (5–25%, w/w) and solution to sample ratio (5:1 – 25:1)
on osmotic dehydration of beetroot were estimated. Quadratic
regression equations describing the effects of these factors on the
water loss and solids gain were developed. It was found that effects
of temperature and salt concentrations were more significant on the
water loss than the effects of processing time and solution to sample
ratio. As for solids gain processing time and salt concentration were
the most significant factors. The osmotic dehydration process was
optimized for water loss, solute gain, and weight reduction. The
optimum conditions were found to be: temperature – 35oC,
processing time – 90 min, salt concentration – 14.31% and solution
to sample ratio 8.5:1. At these optimum values, water loss, solid gain
and weight reduction were found to be 30.86 (g/100 g initial sample),
9.43 (g/100 g initial sample) and 21.43 (g/100 g initial sample)
respectively.
Abstract: For many chemical and biological processes, the understanding of the mixing phenomenon and flow behavior in a stirred tank is of major importance. A three-dimensional numerical study was performed using the software Fluent, to study the flow field in a stirred tank with a Rushton turbine. In this work, we first studied the flow generated in the tank with a Rushton turbine. Then, we studied the effect of the variation of turbine’s submergence on the thermodynamic quantities defining the flow field. For that, four submergences were considered, while maintaining the same rotational speed (N =250rpm). This work intends to optimize the aeration performances of a Rushton turbine in a stirred tank.
Abstract: Cutting fluids, usually in the form of a liquid, are
applied to the chip formation zone in order to improve the cutting
conditions. Cutting fluid can be expensive and represents a biological
and environmental hazard that requires proper recycling and
disposal, thus adding to the cost of the machining operation. For
these reasons dry cutting or dry machining has become an
increasingly important approach; in dry machining no coolant or
lubricant is used. This paper discussed the effect of the dry cutting on
cutting force and tool life when machining aerospace materials
(Haynes 242) with using two different coated carbide cutting tools
(TiAlN and TiN/MT-TiCN/TiN). Response surface method (RSM)
was used to minimize the number of experiments. ParTiAlN Swarm
Optimisation (PSO) models were developed to optimize the
machining parameters (cutting speed, federate and axial depth) and
obtain the optimum cutting force and tool life. It observed that
carbide cutting tool coated with TiAlN performed better in dry
cutting compared with TiN/MT-TiCN/TiN. On other hand, TiAlN
performed more superior with using of 100 % water soluble coolant.
Due to the high temperature produced by aerospace materials, the
cutting tool still required lubricant to sustain the heat transfer from
the workpiece.
Abstract: One of the most basic functions of control engineers is
tuning of controllers. There are always several process loops in the
plant necessitate of tuning. The auto tuned Proportional Integral
Derivative (PID) Controllers are designed for applications where
large load changes are expected or the need for extreme accuracy and
fast response time exists. The algorithm presented in this paper is
used for the tuning PID controller to obtain its parameters with a
minimum computing complexity. It requires continuous analysis of
variation in few parameters, and let the program to do the plant test
and calculate the controller parameters to adjust and optimize the
variables for the best performance. The algorithm developed needs
less time as compared to a normal step response test for continuous
tuning of the PID through gain scheduling.