Abstract: A lot of recent research have spoken on the relation
between the increase of the homocysteinemia and some kinds of
cancer . For that, our study was based on the research of a possible
relation between the increase of the concentration of this amino-acid
in the plasma and the appearance of the disease of the Acute
Lymphoblastic Leukaemia in a part of Algerian children with Berber
origin in the East of Algeria . The study has done on 47 ill persons
with an average age of (09±06 ) years , with whom the disease has
diagnosed by blood and marrow examination in the hospital of blood
diseases in the CHU of Batna, and on 194 healthy witnesses of the
same age. The two groups were benefited by a dosage of the
concentration of the homocysteine vitamin B9 ,vitamin B12 , and
also of the study of special polymorphisms of indispensable enzymes
in the metabolism of this acid , and that by the use of the method (
Light cycler ) Real time PCR , on the following enzymes : MS (
C2756G ), MSR ( A66G ) ,MTHFR1 ( C677T ) and MTHFR2
(A1298C). The obtained results have revealed that the rate of the
homozygote muted genotype is the less frequent in the two groups ,
and that exist at list one genotype of each enzyme in the ill group and
in which the percentage exceed with remarkable way the same
genotype in the healthy group and we notice specially the muted
genotype GG of -the methionine synthetase-and the form TT of the
enzyme – methyline tetra hydrofolate reductase – We notice the
existence of considerable number of genotypes in the ill group lied
with characteristic increase of this Amino-acid ,and that for the
reduction of the biologic activity of these enzymes which become
inefficient in the transfer of the homocysteine into the methionine
and cause the diminution of the biologic activity of these enzymes
and with consequence the reduction of the percentage of methylic
radicals in the DNA of studied genes and that lead to the increase of
the activity and the capacity of transcription , and it-s so probably
that this last one is one of the factors of this disease especially if we
know that the specific check-up of vitamins is normal and similar in
the two groups , which ovoid the hypothesis of the reduction of
vitamins . We notice also that the heterozygote genotype is the less in
the sick category except the MTHFR2. Wild genotype is more
frequent in the witness group except MSR. Even these results are
partials; they open a new way in the genetic diagnosis of this
malicious disease which allow a precocious diagnosis and the use of
an effective and appropriated treatment in the same time.
Abstract: Facing the concern of the population to its environment and to climatic change, city planners are now considering the urban climate in their choices of planning. The urban climate, representing different urban morphologies across central Bangkok metropolitan area (BMA), are used to investigates the effects of both the composition and configuration of variables of urban morphology indicators on the summer diurnal range of urban climate, using correlation analyses and multiple linear regressions. Results show first indicate that approximately 92.6% of the variation in the average maximum daytime near-surface air temperature (Ta) was explained jointly by the two composition variables of urban morphology indicators including open space ratio (OSR) and floor area ratio (FAR). It has been possible to determine the membership of sample areas to the local climate zones (LCZs) using these urban morphology descriptors automatically computed with GIS and remote sensed data. Finally result found the temperature differences among zones of large separation, such as the city center could be respectively from 35.48±1.04ºC (Mean±S.D.) warmer than the outskirt of Bangkok on average for maximum daytime near surface temperature to 28.27±0.21ºC for extreme event and, can exceed as 8ºC. A spatially disaggregation of urban thermal responsiveness map would be helpful for several reasons. First, it would localize urban areas concerned by different climate behavior over summer daytime and be a good indicator of urban climate variability. Second, when overlaid with a land cover map, this map may contribute to identify possible urban management strategies to reduce heat wave effects in BMA.
Abstract: Plackett-Burman statistical screening of media
constituents and operational conditions for extracellular lipase
production from isolate Trichoderma viride has been carried out in
submerged fermentation. This statistical design is used in the early
stages of experimentation to screen out unimportant factors from a
large number of possible factors. This design involves screening of
up to 'n-1' variables in just 'n' number of experiments. Regression
coefficients and t-values were calculated by subjecting the
experimental data to statistical analysis using Minitab version 15.
The effects of nine process variables were studied in twelve
experimental trials. Maximum lipase activity of 7.83 μmol /ml /min
was obtained in the 6th trail. Pareto chart illustrates the order of
significance of the variables affecting the lipase production. The
present study concludes that the most significant variables affecting
lipase production were found to be palm oil, yeast extract, K2HPO4,
MgSO4 and CaCl2.
Abstract: A design flow of multi-standard down-conversion
CMOS mixers for three modern standards: Global System Mobile,
Digital Enhanced Cordless Telephone and Universal Mobile
Telecommunication Systems is presented. Three active mixer-s
structures are studied. The first is based on the Gilbert cell which
gives a tolerable noise figure and linearity with a low conversion
gain. The second and third structures use the current bleeding and
charge injection techniques in order to increase the conversion gain.
An improvement of about 2 dB of the conversion gain is achieved
without a considerable degradation of the other characteristics. The
models used for noise figure, conversion gain and IIP3 used are
studied. This study describes the nature of trade-offs inherent in such
structures and gives insights that help in identifying which structure
is better for given conditions.
Abstract: For cognitive radio networks, there is a major
spectrum sensing problem, i.e. dynamic spectrum management. It is
an important issue to sense and identify the spectrum holes in
cognitive radio networks. The first-order derivative scheme is usually
used to detect the edge of the spectrum. In this paper, a novel
spectrum sensing technique for cognitive radio is presented. The
proposed algorithm offers efficient edge detection. Then, simulation
results show the performance of the first-order derivative scheme and
the proposed scheme and depict that the proposed scheme obtains
better performance than does the first-order derivative scheme.
Abstract: In this paper, we propose a solution to the motion
control problem of a 2-link revolute manipulator arm. We require the
end-effector of the arm to move safely to its designated target in a
priori known workspace cluttered with fixed circular obstacles of
arbitrary position and sizes. Firstly a unique velocity algorithm is
used to move the end-effector to its target. Secondly, for obstacle
avoidance a turning angle is designed, which when incorporated into
the control laws ensures that the entire robot arm avoids any number
of fixed obstacles along its path enroute the target. The control laws
proposed in this paper also ensure that the equilibrium point of the
system is asymptotically stable. Computer simulations of the
proposed technique are presented.
Abstract: This study aimed to develop and initially validate an instrument that measures social competency among tertiary level faculty members. A review of extant literature on social competence was done. The review of extant literature led to the writing of the items in the initial instrument which was evaluated by 11 Subject Matter Experts (SMEs). The SMEs were either educators or psychologists. The results of the evaluations done by the SMEs served as bases for the creation of the pre-try-out instrument used in the first trial-run. Insights from the first trial-run participants led to the development of the main try-out instrument used in the final test administration. One Hundred Forty-one participants from five private Higher Education Institutions (HEIs) in the National Capital Region (NCR) and five private HEIs in Central Luzon in the Philippines participated in the final test administration. The reliability of the instrument was evaluated using Cronbach-s Coefficient Alpha formula and had a Cronbach-s Alpha of 0.92. On the other hand, Factor Analysis was used to evaluate the validity of the instrument and six factors were identified. The development of the final instrument was based on the results of the evaluation of the instrument-s reliability and validity. For purposes of recognition, the instrument was named “Social Competency Inventory for Tertiary Level Faculty Members (SCI-TLFM)."
Abstract: To achieve reliable solutions, today-s numerical and
experimental activities need developing more accurate methods and
utilizing expensive facilities, respectfully in microchannels. The analytical
study can be considered as an alternative approach to alleviate
the preceding difficulties. Among the analytical solutions, those with
high robustness and low complexities are certainly more attractive.
The perturbation theory has been used by many researchers to analyze
microflows. In present work, a compressible microflow with constant
heat flux boundary condition is analyzed. The flow is assumed to be
fully developed and steady. The Mach and Reynolds numbers are also
assumed to be very small. For this case, the creeping phenomenon
may have some effect on the velocity profile. To achieve robustness
solution it is assumed that the flow is quasi-isothermal. In this study,
the creeping term which appears in the slip boundary condition
is formulated by different mathematical formulas. The difference
between this work and the previous ones is that the creeping term
is taken into account and presented in non-dimensionalized form.
The results obtained from perturbation theory are presented based
on four non-dimensionalized parameters including the Reynolds,
Mach, Prandtl and Brinkman numbers. The axial velocity, normal
velocity and pressure profiles are obtained. Solutions for velocities
and pressure for two cases with different Br numbers are compared
with each other and the results show that the effect of creeping
phenomenon on the velocity profile becomes more important when
Br number is less than O(ε).
Abstract: In this study, single nozzle method used for
electrospinning technique which composite polymer solution with
cellulose nanowiskers (CNW) was treated by ultrasonic sonificator
have been compared with coaxial (double) nozzle method, in terms of
mechanical, thermal and morphological properties of composite
nanofiber. The effect of water content in composite polymer solution
on properties of nanofiber has also been examined. It has been seen
that single nozzle method which polymer solution does not contain
water has better results than that of coaxial method, in terms of
mechanical, thermal and morphological properties of nanofiber.
However, it is necessary to make an optimization study on setting
condition of ultrasonic treatment to get better dispersion of CNW in
composite nanofiber and to get better mechanical and thermal
properties
Abstract: The draft Auckland Unitary Plan outlines the future land used for new housing and businesses with Auckland population growth over the next thirty years. According to Auckland Unitary Plan, over the next 30 years, the population of Auckland is projected to increase by one million, and up to 70% of total new dwellings occur within the existing urban area. Intensification will not only increase the number of median or higher density houses such as terrace house, apartment building, etc. within the existing urban area but also change mean housing design data that can impact building thermal performance under the local climate. Based on mean energy consumption and building design data, and their relationships of a number of Auckland sample houses, this study is to estimate the future mean housing energy consumption associated with the change of mean housing design data and evaluate housing energy efficiency with the Auckland Unitary Plan.
Abstract: In this paper, a new Genetic Algorithm (GA) based
methodology is proposed to optimize the Degree of Hybridization
(DOH) in a passenger parallel hybrid car. At first step, target
parameters for the vehicle are decided and then using ADvanced
VehIcle SimulatOR (ADVISOR) software, the variation pattern of
these target parameters, across the different DOHs, is extracted. At
the next step, a suitable cost function is defined and is optimized
using GA. In this paper, also a new technique has been proposed for
deciding the number of battery modules for each DOH, which leads
to a great improvement in the vehicle performance. The proposed
methodology is so simple, fast and at the same time, so efficient.
Abstract: The contribution is dealing with the influence of high speed parameters on the quality of machined surface. In general the principle of high speed cutting lies in achieving faster machine times with concurrent increase in accuracy and quality of the machined areas in largely irregular, mathematically hard to define shapes. High speed machining is a highly effective method of machining with the following goals: increasing of machining productivity, increasing of quality of the machined surface, improving of machining economy, improving of ecological aspects of machining. This article is based on an experiment performed by the Department of Machining and Assembly of the Faculty of Mechanical Engineering of VŠBTechnical University of Ostrava.
Abstract: The effect of streamwise conduction on the thermal
characteristics of forced convection for nanofluidic flow in
rectangular microchannel heat sinks under isothermal wall has been
investigated. By applying the fin approach, models with and without
streamwise conduction term in the energy equation were developed
for hydrodynamically and thermally fully-developed flow. These two
models were solved to obtain closed form analytical solutions for the
nanofluid and solid wall temperature distributions and the analysis
emphasized details of the variations induced by the streamwise
conduction on the nanofluid heat transport characteristics. The effects
of the Peclet number, nanoparticle volume fraction, thermal
conductivity ratio on the thermal characteristics of forced convection
in microchannel heat sinks are analyzed. Due to the anomalous
increase in the effective thermal conductivity of nanofluid compared
to its base fluid, the effect of streamwise conduction is expected to be
more significant. This study reveals the significance of the effect of
streamwise conduction under certain conditions of which the
streamwise conduction should not be neglected in the forced
convective heat transfer analysis of microchannel heat sinks.
Abstract: Implementing Information Technology/ Information
System (IT/IS) is critical for every industry as its potential benefits
have been to motivate many industries including the Malaysian
construction industry to invest in it. To successfully implement IT/IS
has become the major concern for every organisation. Identifying the
critical success factors (CSFs) has become the main agenda for
researchers, academicians and practitioners due to the wide number
of failures reported. This research paper seeks to identify the CSFs
that influence the successful implementation of IT/IS in construction
industry in Malaysia. Limited factors relating to people issue will be
highlighted here to showcase some as it becomes one of the major
contributing factors to the failure. Three (3) organisations have
participated in this study. Semi-structured interviews are employed as
they offer sufficient flexibility to ensure that all relevant factors are
covered. Several key issues contributing to successful
implementations of IT/IS are identified. The results of this study
reveal that top management support, communication, user
involvement, IT staff roles and responsibility, training/skills, leader/
IT Leader, organisation culture, knowledge/ experience, motivation,
awareness, focus and ambition, satisfaction, teamwork/ collaboration,
willingness to change, attitude, commitment, management style,
interest in IT, employee behaviour towards collaborative
environment, trust, interpersonal relationship, personal characteristic
and competencies are significantly associated with the successful
implementations of IT/IS. It is anticipated that this study will create
awareness and contribute to a better understanding amongst
construction industry players and will assist them to successfully
implement IT/IS.
Abstract: The flow and heat transfer characteristics for natural
convection along an inclined plate in a saturated porous medium with
an applied magnetic field have been studied. The fluid viscosity has
been assumed to be an inverse function of temperature. Assuming
temperature vary as a power function of distance. The transformed
ordinary differential equations have solved by numerical integration
using Runge-Kutta method. The velocity and temperature profile
components on the plate are computed and discussed in detail for
various values of the variable viscosity parameter, inclination angle,
magnetic field parameter, and real constant (λ). The results have also
been interpreted with the aid of tables and graphs. The numerical
values of Nusselt number have been calculated for the mentioned
parameters.
Abstract: Circular tubes have been widely used as structural
members in engineering application. Therefore, its collapse behavior
has been studied for many decades, focusing on its energy absorption
characteristics. In order to predict the collapse behavior of members,
one could rely on the use of finite element codes or experiments.
These tools are helpful and high accuracy but costly and require
extensive running time. Therefore, an approximating model of tubes
collapse mechanism is an alternative for early step of design. This
paper is also aimed to develop a closed-form solution of thin-walled
circular tube subjected to bending. It has extended the Elchalakani et
al.-s model (Int. J. Mech. Sci.2002; 44:1117-1143) to include the
rate of energy dissipation of rolling hinge in the circumferential
direction. The 3-D geometrical collapse mechanism was analyzed by
adding the oblique hinge lines along the longitudinal tube within the
length of plastically deforming zone. The model was based on the
principal of energy rate conservation. Therefore, the rates of internal
energy dissipation were calculated for each hinge lines which are
defined in term of velocity field. Inextensional deformation and
perfect plastic material behavior was assumed in the derivation of
deformation energy rate. The analytical result was compared with
experimental result. The experiment was conducted with a number of
tubes having various D/t ratios. Good agreement between analytical
and experiment was achieved.
Abstract: The present work describes an experimental
investigation concerning the determination of viscosity behavior with
shear rate and temperature of edible oils: canola; sunflower; corn;
soybean and the no edible oil: Jatropha curcas. Besides these, it was
tested a blend of canola, corn and sunflower oils as well as sunflower
and soybean biodiesel. Based on experiments, it was obtained shear
stress and viscosity at different shear rates of each sample at 40ºC, as
well as viscosity of each sample at various temperatures in the range
of 24 to 85ºC. Furthermore, it was compared the curves obtained for
the viscosity versus temperature with the curves obtained by
modeling the viscosity dependency on temperature using the Vogel
equation. Also a test in a stationary engine was performed in order to
study the energy generation using blends of soybean oil and soybean
biodiesel with diesel.
Abstract: This study investigated climatic factors associated
with influenza cases in Southern Thailand. The main aim for use
regression analysis to investigate possible causual relationship of
climatic factors and variability between the border of the Andaman
Sea and the Gulf of Thailand. Southern Thailand had the highest
Influenza incidences among four regions (i.e. north, northeast, central
and southern Thailand). In this study, there were 14 climatic factors:
mean relative humidity, maximum relative humidity, minimum
relative humidity, rainfall, rainy days, daily maximum rainfall,
pressure, maximum wind speed, mean wind speed, sunshine duration,
mean temperature, maximum temperature, minimum temperature,
and temperature difference (i.e. maximum – minimum temperature).
Multiple stepwise regression technique was used to fit the statistical
model. The results indicated that the mean wind speed and the
minimum relative humidity were positively associated with the
number of influenza cases on the Andaman Sea side. The maximum
wind speed was positively associated with the number of influenza
cases on the Gulf of Thailand side.
Abstract: Bionanotechnology deals with nanoscopic interactions between nanostructured materials and biological systems. Polymer nanocomposites with optimized biological activity have attracted great attention. Nanoclay is considered as reinforcing nanofiller in manufacturing of high performance nanocomposites. In current study, organomodified-nanoclay with negatively charged silicate layers was incorporated into biomedical grade silicone rubber. Nanoparticle loading has been tailored to enhance cell behavior. Addition of nanoparticles led to improved mechanical properties of substrate with enhanced strength and stiffness while no toxic effects was observed. Results indicated improved viability and proliferation of cells by addition of nanofillers. The improved mechanical properties of the matrix result in proper cell response through adjustment and arrangement of cytoskeletal fibers. Results can be applied in tissue engineering when enhanced substrates are required for improvement of cell behavior for in vivo applications.
Abstract: In this paper we developed the Improved Runge-Kutta Nystrom (IRKN) method for solving second order ordinary differential equations. The methods are two step in nature and require lower number of function evaluations per step compared with the existing Runge-Kutta Nystrom (RKN) methods. Therefore, the methods are computationally more efficient at achieving the higher order of local accuracy. Algebraic order conditions of the method are obtained and the third and fourth order method are derived with two and three stages respectively. The numerical results are given to illustrate the efficiency of the proposed method compared to the existing RKN methods.