Abstract: MicroRNAs are small non-coding RNA found in
many different species. They play crucial roles in cancer such as
biological processes of apoptosis and proliferation. The identification
of microRNA-target genes can be an essential first step towards to
reveal the role of microRNA in various cancer types. In this paper,
we predict miRNA-target genes for lung cancer by integrating
prediction scores from miRanda and PITA algorithms used as a
feature vector of miRNA-target interaction. Then, machine-learning
algorithms were implemented for making a final prediction. The
approach developed in this study should be of value for future studies
into understanding the role of miRNAs in molecular mechanisms
enabling lung cancer formation.
Abstract: This paper presents an analysis study on the impacts
of the changes of the capacitor banks, the loss of a transformer, and
the installation of distributed generation on the voltage total harmonic
distortion and harmonic resonance. The study is applied in a real
system in Oman, Sohar Industrial Port–C Substation Network.
Frequency scan method and Fourier series analysis method are used
with the help of EDSA software. Moreover, the results are compared
with limits specified by national Oman distribution code.
Abstract: In recent years, a wide variety of applications are developed with Support Vector Machines -SVM- methods and Artificial Neural Networks -ANN-. In general, these methods depend on intrusion knowledge databases such as KDD99, ISCX, and CAIDA among others. New classes of detectors are generated by machine learning techniques, trained and tested over network databases. Thereafter, detectors are employed to detect anomalies in network communication scenarios according to user’s connections behavior. The first detector based on training dataset is deployed in different real-world networks with mobile and non-mobile devices to analyze the performance and accuracy over static detection. The vulnerabilities are based on previous work in telemedicine apps that were developed on the research group. This paper presents the differences on detections results between some network scenarios by applying traditional detectors deployed with artificial neural networks and support vector machines.
Abstract: The effectiveness of microchannels in enhancing heat
transfer has been demonstrated in the semiconductor industry. In
order to tap the microscale heat transfer effects into macro
geometries, overcoming the cost and technological constraints,
microscale passages were created in macro geometries machined
using conventional fabrication methods. A cylindrical insert was
placed within a pipe, and geometrical profiles were created on the
outer surface of the insert to enhance heat transfer under steady-state
single-phase liquid flow conditions. However, while heat transfer
coefficient values of above 10 kW/m2·K were achieved, the heat
transfer enhancement was accompanied by undesirable pressure drop
increment. Therefore, this study aims to address the high pressure
drop issue using Constructal theory, a universal design law for both
animate and inanimate systems. Two designs based on Constructal theory were developed to study
the effectiveness of Constructal features in reducing the pressure drop
increment as compared to parallel channels, which are commonly
found in microchannel fabrication. The hydrodynamic and heat
transfer performance for the Tree insert and Constructal fin (Cfin)
insert were studied using experimental methods, and the underlying
mechanisms were substantiated by numerical results. In technical
terms, the objective is to achieve at least comparable increment in
both heat transfer coefficient and pressure drop, if not higher
increment in the former parameter. Results show that the Tree insert improved the heat transfer
performance by more than 16 percent at low flow rates, as compared
to the Tree-parallel insert. However, the heat transfer enhancement
reduced to less than 5 percent at high Reynolds numbers. On the
other hand, the pressure drop increment stayed almost constant at 20
percent. This suggests that the Tree insert has better heat transfer
performance in the low Reynolds number region. More importantly,
the Cfin insert displayed improved heat transfer performance along
with favourable hydrodynamic performance, as compared to Cfinparallel
insert, at all flow rates in this study. At 2 L/min, the
enhancement of heat transfer was more than 30 percent, with 20
percent pressure drop increment, as compared to Cfin-parallel insert.
Furthermore, comparable increment in both heat transfer coefficient
and pressure drop was observed at 8 L/min. In other words, the Cfin
insert successfully achieved the objective of this study. Analysis of the results suggests that bifurcation of flows is
effective in reducing the increment in pressure drop relative to heat
transfer enhancement. Optimising the geometries of the Constructal
fins is therefore the potential future study in achieving a bigger stride
in energy efficiency at much lower costs.
Abstract: Flue gas desulfurization gypsum (FGD) is a waste
material arouse from coal power plants. Hydroxyapatite (HAP) is a
biomaterial with porous structure. In this study, FGD gypsum which
retrieved from coal power plant in Turkey was characterized and
HAP particles which can be used as an adsorbent in wastewater
treatment application were synthesized from the FGD gypsum. The
raw materials are characterized by using X Ray Diffraction (XRD)
and Fourier transform infrared spectroscopy (FT-IR) techniques and
produced HAP are characterized by using XRD. As a result, HAP
particles were synthesized at the molar ratio of 5:10, 5:15, 5:20, 5:24,
at room temperature, in alkaline medium (pH=11) and in 1 hour-reaction
time. Among these conditions, 5:20 had the best result.
Abstract: Digital technologies offer many opportunities in the
design and implementation of brand communication and advertising.
Augmented reality (AR) is an innovative technology in marketing
communication that focuses on the fact that virtual interaction with a
product ad offers additional value to consumers. AR enables
consumers to obtain (almost) real product experiences by the way of
virtual information even before the purchase of a certain product.
Aim of AR applications in relation with advertising is in-depth
examination of product characteristics to enhance product knowledge
as well as brand knowledge. Interactive design of advertising
provides observers with an intense examination of a specific
advertising message and therefore leads to better brand knowledge.
The elaboration likelihood model and the central route to persuasion
strongly support this argumentation. Nevertheless, AR in brand
communication is still in an initial stage and therefore scientific
findings about the impact of AR on information processing and brand
attitude are rare. The aim of this paper is to empirically investigate
the potential of AR applications in combination with traditional print
advertising. To that effect an experimental design with different
levels of interactivity is built to measure the impact of interactivity of
an ad on different variables o advertising effectiveness.
Abstract: Device-to-device (D2D) communication is considered a
promising technique to provide wireless peer-to-peer communication
services. Due to increasing demand on mobile services, available
spectrum for radio frequency (RF) based communications becomes
scarce. Recently, visible light communications (VLC) has evolved
as a high speed wireless data transmission technology for indoor
environments with abundant available bandwidth. In this paper,
a novel VLC based D2D communication that provides wireless
peer-to-peer communication is proposed. Potential low operating
power devices for an efficient D2D communication over increasing
distance of separation between devices is analyzed. Optical repeaters
(OR) are also proposed to enhance the performance in an environment
where direct D2D communications yield degraded performance.
Simulation results show that VLC plays an important role in
providing efficient D2D communication up to a distance of 1 m
between devices. It is also found that the OR significantly improves
the coverage distance up to 3.5 m.
Abstract: The aim of this article is to identify the measures
companies undertake in order to adapt to the environment as well as
discussing their diversity and effectiveness. The research methods
used in the study include an in-depth analysis of the literature and a
case study, which helps to illustrate the issue in question. Referring to
the concept of agility, which is firmly embedded in the theory of
strategic management and has been developed with the aim of
adapting to the environment and its changes, the paper first examines
different types of adaptation measures for companies. Then the issue
under discussion is illustrated with the example of the company
Hortimex. This company is an eminent representative of the world’s
leading manufacturers of food additives and ingredients. The
company was established in 1988 and is a family business, which in
practice means that it conducts business in a responsible manner,
observing the law and respecting the interests of society and the
environment. The company’s mission is to develop a market in
Poland for the products and solutions offered by their partners and to
share their knowledge of additives in food production and
consumption.
Abstract: In this paper, a desiccant solar unit for air
conditioning and desalination is presented first. Secondly, a dynamic
modelling study of the desiccant wheel is developed. After that, a
simulation study and an experimental investigation of the behaviour
of desiccant wheel are developed. The experimental investigation is
done in the chamber of commerce in Freiburg-Germany. Indeed, the
variations of calculated and measured temperatures and specific
humidity of dehumidified and rejected air are presented where a good
agreement is found when comparing the model predictions with
experimental data under the considered range of operating conditions.
Finally, the study of the compartments of desalination and water
condensation shows that the unit can produce an acceptable quantity
of water at the same time of the air conditioning operation.
Abstract: This research provides a technical account of
estimating Transition Probability using Time-homogeneous Markov
Jump Process applying by South African HIV/AIDS data from the
Statistics South Africa. It employs Maximum Likelihood Estimator
(MLE) model to explore the possible influence of Transition
Probability of mortality cases in which case the data was based on
actual Statistics South Africa. This was conducted via an integrated
demographic and epidemiological model of South African HIV/AIDS
epidemic. The model was fitted to age-specific HIV prevalence data
and recorded death data using MLE model. Though the previous
model results suggest HIV in South Africa has declined and AIDS
mortality rates have declined since 2002 – 2013, in contrast, our
results differ evidently with the generally accepted HIV models
(Spectrum/EPP and ASSA2008) in South Africa. However, there is
the need for supplementary research to be conducted to enhance the
demographic parameters in the model and as well apply it to each of
the nine (9) provinces of South Africa.
Abstract: The Flexible AC Transmission System (FACTS)
technology is a new advanced solution that increases the reliability
and provides more flexibility, controllability, and stability of a power
system. The Unified Power Flow Controller (UPFC), as the most
versatile FACTS device for regulating power flow, is able to control
respectively transmission line real power, reactive power, and node
voltage. The main purpose of this paper is to analyze the effect of the
UPFC on the load flow, the power losses, and the voltage stability
using NEPLAN software modules, Newton-Raphson load flow is
used for the power flow analysis and the modal analysis is used for
the study of the voltage stability. The simulation was carried out on
the IEEE 14-bus test system.
Abstract: The combination of the properties of graphene oxide
(OG) and PVDF homopolymer makes their combined composite
materials as multifunctional systems with great potential. Knowledge
of the molecular structure is essential for better use. In this work, the
degradation of PVDF polymer exposed to gamma irradiation in
oxygen atmosphere in high dose rate has been studied and compared
to degradation of PVDF/OG composites. The samples were irradiated
with a Co-60 source at constant dose rate, with doses ranging from
100 kGy to 1,000 kGy. In FTIR data shown that the formation of
oxidation products was at the both samples with formation of
carbonyl and hydroxyl groups amongst the most prevalent products
in the pure PVDF samples. In the other hand, the composites samples
exhibit less presence of degradation products with predominant
formation of carbonyl groups, these results also seen in the UV-Vis
analysis. The results show that the samples of composites may have
greater resistance to the irradiation process, since they have less
degradation products than pure PVDF samples seen by spectroscopic
techniques.
Abstract: Autologous Chondrocyte Implantation (ACI) is used worldwide since 1998 to treat cartilage defect. GEL based ACI is a new tissue-engineering technique to treat full thickness cartilage defect with fibrin and thrombin as scaffold for chondrocytes. Purpose of this study is to see safety and efficacy of gel based ACI for knee cartilage defect in multiple centres with different surgeons. Gel-based Autologous Chondrocyte Implantation (GACI) has shown effectiveness in treating isolated cartilage defect of knee joint. Long term results are still needed to be studied. This study was followed-up up to two years and showed benefit to patients. All enrolled patients with a mean age of 28.5 years had an average defect size of3 square centimeters, and were grade IV as per ICRS grading. All patients were followed up several times and at several intervals at 6th week, 8th week, 11th week, 17th week, 29th week, 57th week after surgery. The outcomes were measured based on the IKDC (subjective and objective) and MOCART scores.
Abstract: Microstructure and fabric of soils play an important
role on structural properties e.g. stiffness and strength of compacted
earthwork. Traditional quality control monitoring based on moisturedensity
tests neither reflects the variability of soil microstructure nor
provides a direct assessment of structural property, which is the
ultimate objective of the earthwork quality control. Since stiffness
and strength are sensitive to soil microstructure and fabric, any
independent test methods that provide simple, rapid, and direct
measurement of stiffness and strength are anticipated to provide an
effective assessment of compacted earthen materials’ uniformity. In
this study, the soil stiffness gauge (SSG) and the dynamic cone
penetrometer (DCP) were respectively utilized to measure and
monitor the stiffness and strength in companion with traditional
moisture-density measurements of various earthen materials used in
Thailand road construction projects. The practical earthwork quality
control criteria are presented herein in order to assure proper
earthwork quality control and uniform structural property of
compacted earthworks.
Abstract: Community living adjacent to forests and Protected
Areas, especially in South Asian countries, have a common practice
in extracting resources for their living and livelihoods. This
extraction of resources, because the way it is done, destroys the biophysical
features of the area. Deforestation, wildlife poaching, illegal
logging, unauthorized hill cutting etc. are some of the serious issues
of concern for the sustainability of the natural resources that has a
direct impact on environment and climate as a whole. To ensure
community involvement in conservation initiatives of the state,
community based forest management, commonly known as Comanagement,
has been in practice in 6 South Asian countries. These
are -India, Nepal, Sri Lanka, Pakistan, Bhutan and Bangladesh.
Involving community in forestry management was initiated first in
Bangladesh in 1979 and reached as an effective co-management
approach through a several paradigm shifts. This idea of Comanagement
has been institutionalized through a Government Order
(GO) by the Ministry of Environment and Forests, Government of
Bangladesh on November 23, 2009. This GO clearly defines the
structure and functions of Co-management and its different bodies.
Bangladesh Forest Department has been working in association with
community to conserve and manage the Forests and Protected areas
of Bangladesh following this legal document. Demographically
young people constitute the largest segment of population in
Bangladesh. This group, if properly sensitized, can produce valuable
impacts on the conservation initiatives, both by community and
government. This study traced the major factors that motivate
community youths to work effectively with different tiers of comanagement
organizations in conservation of forests and Protected
Areas of Bangladesh. For the purpose of this study, 3 FGDs were
conducted with 30 youths from the community living around the
Protected Areas of Cox’s bazar, South East corner of Bangladesh,
who are actively involved in Co-management organizations. KII were
conducted with 5 key officials of Forest Department stationed at
Cox’s Bazar. 2 FGDs were conducted with the representatives of 7
Co-management organizations working in Cox’s Bazar region and
approaches of different community outreach activities conducted for
forest conservation by 3 private organizations and Projects have been
reviewed. Also secondary literatures were reviewed for the history
and evolution of Co-management in Bangladesh and six South Asian
countries. This study found that innovative community outreach
activities that are financed by public and private sectors involving
youths and community as a whole have played a pivotal role in
conservation of forests and Protected Areas of the region. This
approach can be replicated in other regions of Bangladesh as well as
other countries of South Asia where Co-Management exists in
practice.
Abstract: HMS Industrial Networks AB has been recognized as
one of the most innovative companies in the industrial
communication industry worldwide. The creation of their Anybus
innovation during the 1990s contributed considerably to the
company’s success. From inception, HMS’ employees were
innovating for the purpose of creating new business (the creation
phase). After the Anybus innovation, they began the process of
internationalization (the commercialization phase), which in turn led
them to concentrate on cost reduction, product quality, delivery
precision, operational efficiency, and increasing growth (the growth
phase). As a result of this transformation, performing new radical
innovations have become more complicated. The purpose of our research was to explore the dynamics of
innovation at HMS from the aspect of key actors, activities, and
events, over the three phases, in order to understand what led to the
creation of their Anybus innovation, and why it has become
increasingly challenging for HMS to create new radical innovations
for the future. Our research methodology was based on a longitudinal,
retrospective study from the inception of HMS in 1988 to 2014, a
single case study inspired by the grounded theory approach. We
conducted 47 interviews and collected 1 024 historical documents for
our research. Our analysis has revealed that HMS’ success in creating the
Anybus, and developing a successful business around the innovation,
was based on three main capabilities – cultivating customer relations
on different managerial and organizational levels, inspiring business
relations, and balancing complementary human assets for the purpose
of business creation. The success of HMS has turned the management’s attention away
from past activities of key actors, of their behavior, and how they
influenced and stimulated the creation of radical innovations.
Nowadays, they are rhetorically focusing on creativity and
innovation. All the while, their real actions put emphasis on growth,
cost reduction, product quality, delivery precision, operational
efficiency, and moneymaking. In the process of becoming an
international company, HMS gradually refocused. In so doing they
became profitable and successful, but they also forgot what made
them innovative in the first place. Fortunately, HMS’ management
has come to realize that this is the case and they are now in search of
recapturing innovation once again. Our analysis indicates that HMS’ management is facing several
barriers to innovation related path dependency and other lock-in
phenomena. HMS’ management has been captured, trapped in their
mindset and actions, by the success of the past. But now their future has to be secured, and they have come to realize that moneymaking is
not everything. In recent years, HMS’ management have begun to
search for innovation once more, in order to recapture their past
capabilities for creating radical innovations. In order to unlock their
managerial perceptions of customer needs and their counter-innovation
driven activities and events, to utilize the full potential of
their employees and capture the innovation opportunity for the future.
Abstract: The rapid growth of the human population and the
environmental degradation associated with increased consumption of
resources raises concerns on sustainability. Social sustainability
constitutes one of the three dimensions of sustainability together with
environmental and economic dimensions. Even though there is not an
agreement on what social sustainability consists of, it is a well known
fact that it necessitates user participation. The fore, this study aims to
observe and analyze the role of user participation on social
sustainability. In this paper, the links between user participation and indicators of
social sustainability have been searched. In order to achieve this, first
of all a literature review on social sustainability has been done;
accordingly, the information obtained from researches has been used
in the evaluation of the projects conducted in the developing
countries considering user participation. These examples are taken as
role models with pros and cons for the development of the checklist
for the evaluation of the case studies. Furthermore, a case study over
the post earthquake residential settlements in Turkey have been
conducted. The case study projects are selected considering different building
scales (differing number of residential units), scale of the problem
(post-earthquake settlements, rehabilitation of shanty dwellings) and
the variety of users (differing socio-economic dimensions). Decisionmaking,
design, building and usage processes of the selected projects
and actors of these processes have been investigated in the context of
social sustainability. The cases include: New Gourna Village by
Hassan Fathy, Quinta Monroy dwelling units conducted in Chile by
Alejandro Aravena and Beyköy and Beriköy projects in Turkey
aiming to solve the problem of housing which have appeared after the
earthquake happened in 1999 have been investigated. Results of the
study possible links between social sustainability indicators and user
participation and links between user participation and the
peculiarities of place. Results are compared and discussed in order to find possible
solutions to form social sustainability through user participation.
Results show that social sustainability issues depend on communities'
characteristics, socio-economic conditions and user profile but user
participation has positive effects on some social sustainability
indicators like user satisfaction, a sense of belonging and social
stability.
Abstract: Sentiment analysis (SA) has received growing
attention in Arabic language research. However, few studies have yet
to directly apply SA to Arabic due to lack of a publicly available
dataset for this language. This paper partially bridges this gap due to
its focus on one of the Arabic dialects which is the Saudi dialect. This
paper presents annotated data set of 4700 for Saudi dialect sentiment
analysis with (K= 0.807). Our next work is to extend this corpus and
creation a large-scale lexicon for Saudi dialect from the corpus.
Abstract: Surface characteristics of Bacillus megaterium strain
were investigated; zeta potential, FTIR and contact angle were
measured. Surface energy components including Lifshitz-van der
Waals, Hamaker constant, and acid/base components (Lewis
acid/Lewis base) were calculated from the contact angle data. The
results showed that the microbial cells were negatively charged over
all pH regions with high values at alkaline region. A hydrophilic
nature for the strain was confirmed by contact angle and free energy
of adhesion between microbial cells. Adsorption affinity of the strain
toward dolomite was studied at different pH values. The results
showed that the cells had a high affinity to dolomite at acid pH
comparing to neutral and alkaline pH. Extended DLVO theory was
applied to calculate interaction energy between B. megaterium cells
and dolomite particles. The adsorption results were in agreement with
the results of Extended DLVO approach. Surface changes occurred
on dolomite surface after the bio-treatment were monitored; contact
angle decreased from 69° to 38° and the mineral’s floatability
decreased from 95% to 25% after the treatment.
Abstract: The cumulative costs for O&M may represent as
much as 65%-90% of the turbine's investment cost. Nowadays the
cost effectiveness concept becomes a decision-making and
technology evaluation metric. The cost of energy metric accounts for
the effect replacement cost and unscheduled maintenance cost
parameters. One key of the proposed approach is the idea of
maintaining the WTs which can be captured via use of a finite state
Markov chain. Such a model can be embedded within a probabilistic
operation and maintenance simulation reflecting the action to be
done. In this paper, an approach of estimating the cost of O&M is
presented. The finite state Markov model is used for decision
problems with number of determined periods (life cycle) to predict
the cost according to various options of maintenance.