Abstract: This main purpose of the study reported here was to
investigate the extent to which the form of school
governance (particularly decision-making) had an impact upon the
effectiveness of the school with reference to parental involvement,
planning and budgeting, professional development of teachers,
school facilities and resources, and student outcomes. Particular
attention was given to decision-making within the governance
arrangements. The study was based on four case studies of high
schools in New South Wales, Australia including one government
school, one independent Christian community school, one
independent Catholic school, and one Catholic systemic school.
The focus of the research was principals, teachers, parents, and
students of four schools with varying governance structures. To
gain a greater insight into the issues, the researchers collected
information by questionnaire, semi-structured interview, and
review of school key documents. This study found that it was not
so much structure but the centrality of the school Principal and the
way that the Principal perceived his/her roles in relation to others
that impacted most on school governance.
Abstract: Protein-protein interactions (PPI) play a crucial role in many biological processes such as cell signalling, transcription, translation, replication, signal transduction, and drug targeting, etc. Structural information about protein-protein interaction is essential for understanding the molecular mechanisms of these processes. Structures of protein-protein complexes are still difficult to obtain by biophysical methods such as NMR and X-ray crystallography, and therefore protein-protein docking computation is considered an important approach for understanding protein-protein interactions. However, reliable prediction of the protein-protein complexes is still under way. In the past decades, several grid-based docking algorithms based on the Katchalski-Katzir scoring scheme were developed, e.g., FTDock, ZDOCK, HADDOCK, RosettaDock, HEX, etc. However, the success rate of protein-protein docking prediction is still far from ideal. In this work, we first propose a more practical measure for evaluating the success of protein-protein docking predictions,the rate of first success (RFS), which is similar to the concept of mean first passage time (MFPT). Accordingly, we have assessed the ZDOCK bound and unbound benchmarks 2.0 and 3.0. We also createda new benchmark set for protein-protein docking predictions, in which the complexes have experimentally determined binding affinity data. We performed free energy calculation based on the solution of non-linear Poisson-Boltzmann equation (nlPBE) to improve the binding mode prediction. We used the well-studied thebarnase-barstarsystem to validate the parameters for free energy calculations. Besides,thenlPBE-based free energy calculations were conducted for the badly predicted cases by ZDOCK and ZRANK. We found that direct molecular mechanics energetics cannot be used to discriminate the native binding pose from the decoys.Our results indicate that nlPBE-based calculations appeared to be one of the promising approaches for improving the success rate of binding pose predictions.
Abstract: Digital signature is a useful primitive to attain the integrity and authenticity in various wire or wireless communications. Proxy signature is one type of the digital signatures. It helps the proxy signer to sign messages on behalf of the original signer. It is very useful when the original signer (e.g. the president of a company) is not available to sign a specific document. If the original signer can not forge valid proxy signatures through impersonating the proxy signer, it will be robust in a virtual environment; thus the original signer can not shift any illegal action initiated by herself to the proxy signer. In this paper, we propose a new proxy signature scheme. The new scheme can prevent the original signer from impersonating the proxy signer to sign messages. The proposed scheme is based on the regular ElGamal signature. In addition, the fair privacy of the proxy signer is maintained. That means, the privacy of the proxy signer is preserved; and the privacy can be revealed when it is necessary.
Abstract: The information on the Web increases tremendously.
A number of search engines have been developed for searching Web
information and retrieving relevant documents that satisfy the
inquirers needs. Search engines provide inquirers irrelevant
documents among search results, since the search is text-based rather
than semantic-based. Information retrieval research area has
presented a number of approaches and methodologies such as
profiling, feedback, query modification, human-computer interaction,
etc for improving search results. Moreover, information retrieval has
employed artificial intelligence techniques and strategies such as
machine learning heuristics, tuning mechanisms, user and system
vocabularies, logical theory, etc for capturing user's preferences and
using them for guiding the search based on the semantic analysis
rather than syntactic analysis. Although a valuable improvement has
been recorded on search results, the survey has shown that still
search engines users are not really satisfied with their search results.
Using ontologies for semantic-based searching is likely the key
solution. Adopting profiling approach and using ontology base
characteristics, this work proposes a strategy for finding the exact
meaning of the query terms in order to retrieve relevant information
according to user needs. The evaluation of conducted experiments
has shown the effectiveness of the suggested methodology and
conclusion is presented.
Abstract: In this paper, an intelligent algorithm for optimal
document archiving is presented. It is kown that electronic archives
are very important for information system management. Minimizing
the size of the stored data in electronic archive is a main issue to
reduce the physical storage area. Here, the effect of different types of
Arabic fonts on electronic archives size is discussed. Simulation
results show that PDF is the best file format for storage of the Arabic
documents in electronic archive. Furthermore, fast information
detection in a given PDF file is introduced. Such approach uses fast
neural networks (FNNs) implemented in the frequency domain. The
operation of these networks relies on performing cross correlation in
the frequency domain rather than spatial one. It is proved
mathematically and practically that the number of computation steps
required for the presented FNNs is less than that needed by
conventional neural networks (CNNs). Simulation results using
MATLAB confirm the theoretical computations.
Abstract: Chikungunya virus (CHICKV) is an arboviruses belonging to family Tagoviridae and is transmitted to human through by mosquito (Aedes aegypti and Aedes albopictus) bite. A large outbreak of chikungunya has been reported in India between 2006 and 2007, along with several other countries from South-East Asia and for the first time in Europe. It was for the first time that the CHICKV outbreak has been reported with mortality from Reunion Island and increased mortality from Asian countries. CHICKV affects all age groups, and currently there are no specific drugs or vaccine to cure the disease. The need of antiviral agents for the treatment of CHICKV infection and the success of virtual screening against many therapeutically valuable targets led us to carry out the structure based drug design against Chikungunya nSP2 protease (PDB: 3TRK). Highthroughput virtual screening of publicly available databases, ZINC12 and BindingDB, has been carried out using the Openeye tools and Schrodinger LLC software packages. Openeye Filter program has been used to filter the database and the filtered outputs were docked using HTVS protocol implemented in GLIDE package of Schrodinger LLC. The top HITS were further used for enriching the similar molecules from the database through vROCS; a shape based screening protocol implemented in Openeye. The approach adopted has provided different scaffolds as HITS against CHICKV protease. Three scaffolds: Indole, Pyrazole and Sulphone derivatives were selected based on the docking score and synthetic feasibility. Derivatives of Pyrazole were synthesized and submitted for antiviral screening against CHICKV.
Abstract: With the advance of multimedia and diagnostic
images technologies, the number of radiographic images is increasing
constantly. The medical field demands sophisticated systems for
search and retrieval of the produced multimedia document. This
paper presents an ongoing research that focuses on the semantic
content of radiographic image documents to facilitate semantic-based
radiographic image indexing and a retrieval system. The proposed
model would divide a radiographic image document, based on its
semantic content, and would be converted into a logical structure or
a semantic structure. The logical structure represents the overall
organization of information. The semantic structure, which is bound
to logical structure, is composed of semantic objects with
interrelationships in the various spaces in the radiographic image.
Abstract: Countries in recession, among them Croatia, have
lower tax revenues as a result of unfavorable economic situation,
which is decrease of the economic activities and unemployment. The
global tax base has decreased. In order to create larger state revenues,
states use the institute of tax authorities. By controlling transfer
pricing in the international companies and using certain techniques,
tax authorities can create greater tax obligations for the companies in
a short period of time.
Abstract: XML is a markup language which is becoming the
standard format for information representation and data exchange. A
major purpose of XML is the explicit representation of the logical
structure of a document. Much research has been performed to
exploit logical structure of documents in information retrieval in
order to precisely extract user information need from large
collections of XML documents. In this paper, we describe an XML
information retrieval weighting scheme that tries to find the most
relevant elements in XML documents in response to a user query.
We present this weighting model for information retrieval systems
that utilize plausible inferences to infer the relevance of elements in
XML documents. We also add to this model the Dempster-Shafer
theory of evidence to express the uncertainty in plausible inferences
and Dempster-Shafer rule of combination to combine evidences
derived from different inferences.
Abstract: Most of the drugs used for pharmaceutical purposes
are poorly water-soluble drugs. About 40% of all newly discovered
drugs are lipophilic and the numbers of lipophilic drugs seem to
increase more and more. Drug delivery systems such as
nanoparticles, micelles or liposomes are applied to improve their
solubility and thus their bioavailability. Besides various techniques of
solubilization, oil-in-water emulsions are often used to incorporate
lipophilic drugs into the oil phase. To stabilize emulsions surface
active substances (surfactants) are generally used. An alternative
method to avoid the application of surfactants was of great interest.
One possibility is to develop O/W-emulsion without any addition of
surface active agents or the so called “surfactant-free emulsion or
SFE”. The aim of this study was to develop and characterize SFE as a
drug carrier by varying the production conditions. Lidocaine base
was used as a model drug. The injection method was developed.
Effects of ultrasound as well as of temperature on the properties of
the emulsion were studied. Particle sizes and release were
determined. The long-term stability up to 30 days was performed.
The results showed that the surfactant-free O/W emulsions with
pharmaceutical oil as drug carrier can be produced.
Abstract: Compression algorithms reduce the redundancy in
data representation to decrease the storage required for that data.
Lossless compression researchers have developed highly
sophisticated approaches, such as Huffman encoding, arithmetic
encoding, the Lempel-Ziv (LZ) family, Dynamic Markov
Compression (DMC), Prediction by Partial Matching (PPM), and
Burrows-Wheeler Transform (BWT) based algorithms.
Decompression is also required to retrieve the original data by
lossless means. A compression scheme for text files coupled with
the principle of dynamic decompression, which decompresses only
the section of the compressed text file required by the user instead of
decompressing the entire text file. Dynamic decompressed files offer
better disk space utilization due to higher compression ratios
compared to most of the currently available text file formats.
Abstract: This study proposes a new recommender system based on the collaborative folksonomy. The purpose of the proposed system is to recommend Internet resources (such as books, articles, documents, pictures, audio and video) to users. The proposed method includes four steps: creating the user profile based on the tags, grouping the similar users into clusters using an agglomerative hierarchical clustering, finding similar resources based on the user-s past collections by using content-based filtering, and recommending similar items to the target user. This study examines the system-s performance for the dataset collected from “del.icio.us," which is a famous social bookmarking website. Experimental results show that the proposed tag-based collaborative and content-based filtering hybridized recommender system is promising and effectiveness in the folksonomy-based bookmarking website.
Abstract: Transportation is one of the most fundamental
challenges of urban development in contemporary world. On the
other hand, sustainable urban development has received tremendous
public attention in the last few years. This trend in addition to other
factors such as energy cost, environmental concerns, traffic
congestion and the feeling of lack of belonging have contributed to
the development of pedestrian areas. The purpose of this paper is to
study the role of walkable streets in sustainable development of
cities. Accordingly, a documentary research through valid sources
has been utilized to substantiate this study. The findings demonstrate
that walking can lead to sustainable urban development from
physical, social, environmental, cultural, economic and political
aspects. Also, pedestrian areas –which are the main context of
walking- act as focal points of development in cities and have a great
effect on modifying and stimulating of their adjacent urban spaces.
Abstract: Heart disease (HD) is a major cause of morbidity and mortality in the modern society. Medical diagnosis is an important but complicated task that should be performed accurately and efficiently and its automation would be very useful. All doctors are unfortunately not equally skilled in every sub specialty and they are in many places a scarce resource. A system for automated medical diagnosis would enhance medical care and reduce costs. In this paper, a new approach based on coactive neuro-fuzzy inference system (CANFIS) was presented for prediction of heart disease. The proposed CANFIS model combined the neural network adaptive capabilities and the fuzzy logic qualitative approach which is then integrated with genetic algorithm to diagnose the presence of the disease. The performances of the CANFIS model were evaluated in terms of training performances and classification accuracies and the results showed that the proposed CANFIS model has great potential in predicting the heart disease.
Abstract: We studied the selection of nest sites by Persian
ground Jay (Podoces pleskei), in a semi -desert central Iran. Habitat
variables such as plant species number, height of plant species,
vegetation percent and distance to water sources of nest sites were
compared with randomly selected non- used sites. The results showed that the most important factors influencing nesting site selection were total vegetation percent and number of shrubs
(Zgophyllum eurypterum and Atraphaxis spinosa). The mean vegetation percent of 20 area selected by Persian Ground Jay was
(4.41+ 0.17), which was significantly larger than that of the non –
selected area (2.08 + 0.06). The number of Zygophyllum eurypterum (1.13+ 0.01) and Atraphaxis spinosa (1.36+ 0.10) were also significantly higher compared with the control area (0.43+ 0.07)
and (0.58+ 0.9) respectively.
Abstract: In this paper we have suggested a new system for egovernment.
In this method a government can design a precise and
perfect system to control people and organizations by using five
major documents. These documents contain the important
information of each member of a society and help all organizations to
do their informatics tasks through them. This information would be
available by only a national code and a secure program would
support it. The suggested system can give a good awareness to the
society and help it be managed correctly.
Abstract: Tehran, one of the heavily-populated capitals, is
severely suffering from increasing air pollution. To show a
documented trend of such pollutants during last years, plane tree
species (Platanus orientalis) were suited to be studied as indicators,
for the species have been planted throughout the city many years
ago. Two areas (Saadatabad and Narmak districts) allotting different
contents of crowed and highly-traffic routs but the same ecological
characteristics were selected. Twelve sample individuals were cored
twice perpendicularly in each area. Tree-rings of each core were
measured by a binocular microscope and separated annually for the
last 25 years. Two heavy metals including Cd and Pb accompanied
by a mineral element (Ca) were analyzed using Hatch method. Treerings
analysis of the two areas showed different groups in term of
physiologically ability as the growths were plunged during the last
10 years in Saadatabad district and showed a slight decrease in the
same period for another studying area. In direct contrast to
decreasing growth trend in Saadatabad, all three mentioned elements
increased sharply during last 25 years in the same area. When it came
to Narmak district, the trend was completely different with
Saadatabad. There were some fluctuations in absorbing trace
elements like tree-rings widths were, yet calcium showed an upward
trend all the last 25 years. The results of the study proved the
possibility of using tree species of each region to monitor its air
pollution trends of the past, hence to depict a pollution assessment of
a populated city for last years and then to make appropriate decisions
for the future as it is well-known what the trend is. On the other
hand, risen values of calcium (as the stress-indicator element)
accompanied by increased trace elements suggests non-sustainable
state of the trees.
Abstract: Our objectives were to evaluate the effects of sire
breed, type of protein supplement, level of supplementation and sex
on wool spinning fineness (SF), its correlations with other wool
characteristics and prediction accuracy in F1 Merino crossbred lambs.
Texel, Coopworth, White Suffolk, East Friesian and Dorset rams
were mated with 500 purebred Merino dams at a ratio of 1:100 in
separate paddocks within a single management system. The F1
progeny were raised on ryegrass pasture until weaning, before forty
lambs were randomly allocated to treatments in a 5 x 2 x 2 x 2
factorial experimental design representing 5 sire breeds, 2
supplementary feeds (canola or lupins), 2 levels of supplementation
(1% or 2% of liveweight) and sex (wethers or ewes). Lambs were
supplemented for six weeks after an initial three weeks of adjustment,
wool sampled at the commencement and conclusion of the feeding
trial and analyzed for SF, mean fibre diameter (FD), coefficient of
variation (CV), standard deviation, comfort factor (CF), fibre
curvature (CURV), and clean fleece yield. Data were analyzed using
mixed linear model procedures with sire fitted as a random effect,
and sire breed, sex, supplementary feed type, level of
supplementation and their second-order interactions as fixed effects.
Sire breed (P
Abstract: The objective of this research intends to create a suitable model of distance training for community leaders in the upper northeastern region of Thailand. The implementation of the research process is divided into four steps: The first step is to analyze relevant documents. The second step deals with an interview in depth with experts. The third step is concerned with constructing a model. And the fourth step takes aim at model validation by expert assessments. The findings reveal the two important components for constructing an appropriate model of distance training for community leaders in the upper northeastern region. The first component consists of the context of technology management, e.g., principle, policy and goals. The second component can be viewed in two ways. Firstly, there are elements comprising input, process, output and feedback. Secondly, the sub-components include steps and process in training. The result of expert assessments informs that the researcher-s constructed model is consistent and suitable and overall the most appropriate.
Abstract: A local municipality has decided to build a sewage pit
to receive residential sewage waste arriving by tank trucks. Daily
accumulated waste are to be pumped to a nearby waste water
treatment facility to be re-consumed for agricultural and construction
projects. A discrete-event simulation model using Arena Software
was constructed to assist in defining the capacity of the system in
cubic meters, number of tank trucks to use the system, number of
unload docks required, number of standby areas needed and
manpower required for data collection at entrance checkpoint and
truck tank load toxicity testing. The results of the model are
statistically validated. Simulation turned out to be an excellent tool
in the facility planning effort for the pit project, as it insured smooth
flow lines of tank trucks load discharge and best utilization of
facilities on site.