Abstract: Electrohydraulic servo system have been used in
industry in a wide number of applications. Its dynamics are highly
nonlinear and also have large extent of model uncertainties and
external disturbances. In this paper, a robust back-stepping control
(RBSC) scheme is proposed to overcome the problem of disturbances
and system uncertainties effectively and to improve the tracking
performance of EHS systems. In order to implement the proposed
control scheme, the system uncertainties in EHS systems are
considered as total leakage coefficient and effective oil volume. In
addition, in order to obtain the virtual controls for stabilizing system,
the update rule for the system uncertainty term is induced by
the Lyapunov control function (LCF). To verify the performance and
robustness of the proposed control system, computer simulation of
the proposed control system using Matlab/Simulink Software
is executed. From the computer simulation, it was found that the
RBSC system produces the desired tracking performance and has
robustness to the disturbances and system uncertainties of EHS
systems.
Abstract: Batch production plants provide a wide range of
scheduling problems. In pharmaceutical industries a batch process
is usually described by a recipe, consisting of an ordering of tasks
to produce the desired product. In this research work we focused
on pharmaceutical production processes requiring the culture of
a microorganism population (i.e. bacteria, yeasts or antibiotics).
Several sources of uncertainty may influence the yield of the culture
processes, including (i) low performance and quality of the cultured
microorganism population or (ii) microbial contamination. For
these reasons, robustness is a valuable property for the considered
application context. In particular, a robust schedule will not collapse
immediately when a cell of microorganisms has to be thrown away
due to a microbial contamination. Indeed, a robust schedule should
change locally in small proportions and the overall performance
measure (i.e. makespan, lateness) should change a little if at all.
In this research work we formulated a constraint programming
optimization (COP) model for the robust planning of antibiotics
production. We developed a discrete-time model with a multi-criteria
objective, ordering the different criteria and performing a
lexicographic optimization. A feasible solution of the proposed
COP model is a schedule of a given set of tasks onto available
resources. The schedule has to satisfy tasks precedence constraints,
resource capacity constraints and time constraints. In particular
time constraints model tasks duedates and resource availability
time windows constraints. To improve the schedule robustness, we
modeled the concept of (a, b) super-solutions, where (a, b) are input
parameters of the COP model. An (a, b) super-solution is one in
which if a variables (i.e. the completion times of a culture tasks)
lose their values (i.e. cultures are contaminated), the solution can be
repaired by assigning these variables values with a new values (i.e.
the completion times of a backup culture tasks) and at most b other
variables (i.e. delaying the completion of at most b other tasks).
The efficiency and applicability of the proposed model is
demonstrated by solving instances taken from a real-life
pharmaceutical company. Computational results showed that
the determined super-solutions are near-optimal.
Abstract: The composite flour blend consisting of corn, pearl
millet, black gram and wheat bran in the ratio of 80:5:10:5 was taken
to prepare the extruded product and their effect on physical properties
of extrudate was studied. The extrusion process was conducted in
laboratory by using twin screw extruder. The physical characteristics
evaluated include lateral expansion, bulk density, water absorption
index, water solubility index, and rehydration ratio and moisture
retention. The Central Composite Rotatable Design (CCRD) was
used to decide the level of processing variables i.e. feed moisture
content (%), screw speed (rpm), and barrel temperature (oC) for the
experiment. The data obtained after extrusion process were analyzed
by using response surface methodology. A second order polynomial
model for the dependent variables was established to fit the
experimental data. The numerical optimization studies resulted in
127°C of barrel temperature, 246 rpm of screw speed, and 14.5% of
feed moisture as optimum variables to produce acceptable extruded
product. The responses predicted by the software for the optimum
process condition resulted in lateral expansion 126%, bulk density
0.28 g/cm3, water absorption index 4.10 g/g, water solubility index
39.90%, rehydration ratio 544% and moisture retention 11.90% with
75% desirability.
Abstract: A flow column has been innovatively used in the
design of a new electrocoagulation reactor (ECR1) that will reduce
the temperature of water being treated; where the flow columns work
as a radiator for the water being treated. In order to investigate the
performance of ECR1 and compare it to that of traditional reactors;
600 mL water samples with an initial temperature of 350C were
pumped continuously through these reactors for 30 min at current
density of 1 mA/cm2. The temperature of water being treated was
measured at 5 minutes intervals over a 30 minutes period using a
thermometer. Additional experiments were commenced to investigate
the effects of initial temperature (15-350C), water conductivity (0.15
– 1.2 S) and current density (0.5 -3 mA/cm2) on the performance of
ECR1.
The results obtained demonstrated that the ECR1, at a current
density of 1 mA/cm2 and continuous flow model, reduced water
temperature from 350C to the vicinity of 280C during the first 15
minutes and kept the same level till the end of the treatment time.
While, the temperature increased from 28.1 to 29.80C and from 29.8
to 31.90C in the batch and the traditional continuous flow models
respectively. In term of initial temperature, ECR1 maintained the
temperature of water being treated within the range of 22 to 280C
without the need for external cooling system even when the initial
temperatures varied over a wide range (15 to 350C). The influent
water conductivity was found to be a significant variable that affect
the temperature. The desirable value of water conductivity is 0.6 S.
However, it was found that the water temperature increased rapidly
with a higher current density.
Abstract: The synthesis of CuFe2O4 spinel powders by an
optimized combustion-like process followed by calcination is
described herein. The samples were characterized using X-ray
diffraction (XRD), differential thermal analysis (TG/DTA), scanning
electron microscopy (SEM), dilatometry and 4-probe DC methods.
Different glycine to nitrate (G/N) ratios of 1 (fuel-deficient), 1.48
(stoichiometric) and 2 (fuel-rich) were employed. Calcining the asprepared
powders at 800 and 1000°C for 5 hours showed that the G/N
ratio of 2 results in the formation of the desired copper spinel single
phase at both calcination temperatures. For G/N=1, formation of
CuFe2O4 takes place in three steps. First, iron and copper nitrates
decompose to iron oxide and pure copper. Then, copper transforms to
copper oxide and finally, copper and iron oxides react with each other
to form a copper ferrite spinel phase. The electrical conductivity and
the coefficient of thermal expansion of the sintered pelletized
samples were 2 S.cm-1 (800°C) and 11×10-6 °C-1 (25-800°C),
respectively.
Abstract: Numerical studies have been carried out using a
validated two-dimensional standard k-omega turbulence model for
the design optimization of a thrust vector control system using shock
induced self-impinging supersonic secondary double jet. Parametric
analytical studies have been carried out at different secondary
injection locations to identifying the highest unsymmetrical
distribution of the main gas flow due to shock waves, which produces
a desirable side force more lucratively for vectoring. The results from
the parametric studies of the case on hand reveal that the shock
induced self-impinging supersonic secondary double jet is more
efficient in certain locations at the divergent region of a CD nozzle
than a case with supersonic single jet with same mass flow rate. We
observed that the best axial location of the self-impinging supersonic
secondary double jet nozzle with a given jet interaction angle, built-in
to a CD nozzle having area ratio 1.797, is 0.991 times the primary
nozzle throat diameter from the throat location. We also observed
that the flexible steering is possible after invoking ON/OFF facility to
the secondary nozzles for meeting the onboard mission requirements.
Through our case studies we concluded that the supersonic self-impinging
secondary double jet at predesigned jet interaction angle
and location can provide more flexible steering options facilitating
with 8.81% higher thrust vectoring efficiency than the conventional
supersonic single secondary jet without compromising the payload
capability of any supersonic aerospace vehicle.
Abstract: Since 1920, the industry has almost completely
changed the rivets production techniques for the manufacture of
permanent welding join production of structures and manufacture of
other products. The welding arc is the process more widely used in
industries. This is accomplished by the heat of an electric arc which
melts the base metal while the molten metal droplets are transferred
through the arc to the welding pool, protected from the atmosphere
by a gas curtain. The GMAW (Gas metal arc welding) process is
influenced by variables such as: current, polarity, welding speed,
electrode: extension, position, moving direction; type of joint,
welder's ability, among others. It is remarkable that the knowledge
and control of these variables are essential for obtaining satisfactory
quality welds, knowing that are interconnected so that changes in one
of them requiring changes in one or more of the other to produce the
desired results. The optimum values are affected by the type of base
metal, the electrode composition, the welding position and the quality
requirements. Thus, this paper proposes a new methodology, adding
the variable vibration through a mechanism developed for GMAW
welding, in order to improve the mechanical and metallurgical
properties which does not affect the ability of the welder and enables
repeatability of the welds made. For confirmation metallographic
analysis and mechanical tests were made.
Abstract: Native American communities are struggling with unemployment and depressed economies. A major cause is a lack of business knowledge, education, and cultural desire. And yet, in the history of the American West, Native Americans were considered the best traders and negotiators for everything from furs to weapons to buffalo. To improve these economies, there has been an effort to reintroduce that heritage to todays and tomorrows generation of tribal members, such Crow, Cheyenne, and Blackfeet. Professors at the College of Business Montana State University-Billings (MSUB) teach tribal students in Montana to create business plans. These plans have won national small business plan competitions. The teaching and advising method used at MSUB is uniquely successful as theses business students are now five time national champions. This article reviews the environment and the method of learning to achieve a winning small business plan with Native American students. It discusses the five plans that became national champions. And it discusses the problems and solutions discovered in the process of achieving results. Students who participated in this endeavor have graduated and become CPAs, MBAs, and gainfully employed in their chosen professions. They have also worked to improve the economies of their native lands and homes. By educating members of these communities with business strategy and plan development, they are better able to impact their own economies.
Abstract: Amoxicillin is an antibiotic which is widely used to
treat various infections in both human beings and animals. However,
when amoxicillin is released into the environment, it is a major
problem. Amoxicillin causes bacterial resistance to these drugs and
failure of treatment with antibiotics. Liquid membrane is of great
interest as a promising method for the separation and recovery of the
target ions from aqueous solutions due to the use of carriers for the
transport mechanism, resulting in highly selectivity and rapid
transportation of the desired metal ions. The simultaneous processes
of extraction and stripping in a single unit operation of liquid
membrane system are very interesting. Therefore, it is practical to
apply liquid membrane, particularly the HFSLM for industrial
applications as HFSLM is proved to be a separation process with
lower capital and operating costs, low energy and extractant with
long life time, high selectivity and high fluxes compared with solid
membranes. It is a simple design amenable to scaling up for industrial
applications. The extraction and recovery for (Amoxicillin) through
the hollow fiber supported liquid membrane (HFSLM) using
aliquat336 as a carrier were explored with the experimental data. The
important variables affecting on transport of amoxicillin viz.
extractant concentration and operating time were investigated. The
highest AMOX- extraction percentages of 85.35 and Amoxicillin
stripping of 80.04 were achieved with the best condition at 6 mmol/L
[aliquat336] and operating time 100 min. The extraction reaction
order (n) and the extraction reaction rate constant (kf) were found to
be 1.00 and 0.0344 min-1, respectively.
Abstract: In this paper, the actuality of the study, and the role of
subjective well-being problem in modern psychology and the
comprehending of subjective well-being by current students is
defined. The purpose of this research is to educe peculiarities of
comprehending of subjective well-being by students with various
levels of emotional intelligence. Methods of research are adapted
Russian-Language questionnaire of K. Riff 'The scales of
psychological well-being'; emotional intelligence questionnaire of D.
V. Lusin. The research involved 72 students from different
universities and disciplines aged between 18 and 24. Analyzing the
results of the studies, it can be concluded that the understanding of
happiness in different groups of students with high and low levels of
overall emotional intelligence is different, as well as differentiated by
gender. Students with a higher level of happiness possess more
capacity and higher need to control their emotions, to cause and
maintain the desired emotions and control something undesirable.
Abstract: In recent years a new method of combination
treatment for cancer has been developed and studied that has led to
significant advancements in the field of cancer therapy. Hyperthermia
is a traditional therapy that, along with a creation of a medically
approved level of heat with the help of an alternating magnetic AC
current, results in the destruction of cancer cells by heat. This paper
gives details regarding the production of the spherical nanocomposite
PVA/γ-Fe2O3 in order to be used for medical purposes such as tumor
treatment by hyperthermia. To reach a suitable and evenly distributed
temperature, the nanocomposite with core-shell morphology and
spherical form within a 100 to 200 nanometer size was created using
phase separation emulsion, in which the magnetic nano-particles γ-
Fe2O3 with an average particle size of 20 nano-meters and with
different percentages of 0.2, 0.4, 0.5 and 0.6 were covered by
polyvinyl alcohol. The main concern in hyperthermia and heat
treatment is achieving desirable specific absorption rate (SAR) and
one of the most critical factors in SAR is particle size. In this project
all attempts has been done to reach minimal size and consequently
maximum SAR. The morphological analysis of the spherical
structure of the nanocomposite PVA/γ-Fe2O3 was achieved by SEM
analyses and the study of the chemical bonds created was made
possible by FTIR analysis. To investigate the manner of magnetic
nanocomposite particle size distribution a DLS experiment was
conducted. Moreover, to determine the magnetic behavior of the γ-
Fe2O3 particle and the nanocomposite PVA/γ-Fe2O3 in different
concentrations a VSM test was conducted. To sum up, creating
magnetic nanocomposites with a spherical morphology that would be
employed for drug loading opens doors to new approaches in
developing nanocomposites that provide efficient heat and a
controlled release of drug simultaneously inside the magnetic field,
which are among their positive characteristics that could significantly
improve the recovery process in patients.
Abstract: This paper focuses on I/O optimizations of N-hybrid
(New-Form of hybrid), which provides a hybrid file system space
constructed on SSD and HDD. Although the promising potentials of
SSD, such as the absence of mechanical moving overhead and high
random I/O throughput, have drawn a lot of attentions from IT
enterprises, its high ratio of cost/capacity makes it less desirable to
build a large-scale data storage subsystem composed of only SSDs. In
this paper, we present N-hybrid that attempts to integrate the strengths
of SSD and HDD, to offer a single, large hybrid file system space.
Several experiments were conducted to verify the performance of
N-hybrid.
Abstract: Tuberculosis (TB) remains a leading cause of
infectious mortality. It is primarily transmitted by the respiratory
route, individuals with active disease may infect others through
airborne particles which releases when they cough, talk, or sing and
subsequently inhale by others. In order to study the effect of the
Bacilli Calmette-Guerin (BCG) vaccine after vaccination of TB
patient, a Vaccinated Susceptible Infected and Recovered (VSIR)
mathematical model is being developed to achieve the desired
objectives. The mathematical model, so developed, shall be used to
quantify the effect of BCG Vaccine to protect the immigrant young
adult person. Moreover, equations are to be established for the
disease endemic and free equilibrium states and subsequently utilized
in disease stability analysis. The stability analysis will give a
complete picture of disease annihilation from the total population if
the total removal rate from the infectious group should be greater
than total number of dormant infections produced throughout
infectious period.
Abstract: High resolution images are always desired as they contain the more information and they can better represent the original data. So, to convert the low resolution image into high resolution interpolation is done. The quality of such high resolution image depends on the interpolation function and is assessed in terms of sharpness of image. This paper focuses on Wavelet based Interpolation Techniques in which an input image is divided into subbands. Each subband is processed separately and finally combined the processed subbandsto get the super resolution image.
Abstract: Under active stress conditions, a rigid cantilever
retaining wall tends to rotate about a pivot point located within the
embedded depth of the wall. For purely granular and cohesive soils, a
methodology was previously reported called minimization of moment
ratio to determine the location of the pivot point of rotation. The
usage of this new methodology is to estimate the rotational stability
safety factor. Moreover, the degree of improvement required in a
backfill to get a desired safety factor can be estimated by the concept
of the shear strength demand. In this article, the accuracy of this
method for another type of cantilever walls called Contiguous Bored
Pile (CBP) retaining wall is evaluated by using physical modeling
technique. Based on observations, the results of moment ratio
minimization method are in good agreement with the results of the
carried out physical modeling.
Abstract: Electrohydraulic servo system have been used in industry in a wide number of applications. Its dynamics are highly nonlinear and also have large extent of model uncertainties and external disturbances. In this paper, a robust back-stepping control (RBSC) scheme is proposed to overcome the problem of disturbances and system uncertainties effectively and to improve the tracking performance of EHS systems. In order to implement the proposed control scheme, the system uncertainties in EHS systems are considered as total leakage coefficient and effective oil volume. In addition, in order to obtain the virtual controls for stabilizing system, the update rule for the system uncertainty term is induced by the Lyapunov control function (LCF). To verify the performance and robustness of the proposed control system, computer simulation of the proposed control system using Matlab/Simulink Software is executed. From the computer simulation, it was found that the RBSC system produces the desired tracking performance and has robustness to the disturbances and system uncertainties of EHS systems.
Abstract: This article proposes a new method for application in
communication circuit systems that increase efficiency, PAE, output
power and gain in the circuit. The proposed method is based on a
combination of switching class-E and class-J and has been termed
class-EJ. This method was investigated using both theory and
simulation to confirm ∼72% PAE and output power of >39dBm. The
combination and design of the proposed power amplifier accrues gain
of over 15dB in the 2.9 to 3.5GHz frequency bandwidth. This circuit
was designed using MOSFET and high power transistors. The loadand
source-pull method achieved the best input and output networks
using lumped elements. The proposed technique was investigated for
fundamental and second harmonics having desirable amplitudes for
the output signal.
Abstract: In this paper, a summary of analytical and
experimental studies into the behavior of a new hysteretic damper,
designed for seismic protection of structures is presented. The Multidirectional
Torsional Hysteretic Damper (MRSD) is a patented
invention in which a symmetrical arrangement of identical cylindrical
steel cores is so configured as to yield in torsion while the structure
experiences planar movements due to earthquake shakings. The new
device has certain desirable properties. Notably, it is characterized by
a variable and controllable-via-design post-elastic stiffness. The
mentioned property is a result of MRSD’s kinematic configuration
which produces this geometric hardening, rather than being a
secondary large-displacement effect. Additionally, the new system is
capable of reaching high force and displacement capacities, shows
high levels of damping, and very stable cyclic response. The device
has gone through many stages of design refinement, multiple
prototype verification tests and development of design guide-lines
and computer codes to facilitate its implementation in practice.
Practicality of the new device, as offspring of an academic sphere, is
assured through extensive collaboration with industry in its final
design stages, prototyping and verification test programs.
Abstract: White concrete facade elements are widely used in
construction industry. It is challenging to achieve the desired
workability in casting of white concrete elements. Particle Matrix
model was used for proportioning the self-compacting white concrete
(SCWC) to control segregation and bleeding and to improve
workability. The paper presents how to reach the target slump flow
while controlling bleeding and segregation in SCWC. The amount of
aggregates, binders and mixing water, as well as type and dosage of
superplasticizer (SP) to be used are the major factors influencing the
properties of SCWC. Slump flow and compressive strength tests were
carried out to examine the performance of SCWC, and the results
indicate that the particle matrix model could produce successfully
SCWC controlling segregation and bleeding.
Abstract: Plasmin plays an important role in the human
circulatory system owing to its catalytic ability of fibrinolysis. The
immediate injection of plasmin in patients of strokes has intrigued
many scientists to design vectors that can transport plasmin to the
desired location in human body. Here we predict the structure of
human plasmin and investigate the interaction of plasmin with the
gold-nanoparticle.
Because the crystal structure of plasminogen has been solved, we
deleted N-terminal domain (Pan-apple domain) of plasminogen and
generate a mimic of the active form of this enzyme (plasmin). We
conducted a simulated annealing process on plasmin and discovered a
very large conformation occurs. Kringle domains 1, 4 and 5 had been
observed to leave its original location relative to the main body of the
enzyme and the original doughnut shape of this enzyme has been
transformed to a V-shaped by opening its two arms. This observation
of conformational change is consistent with the experimental results of
neutron scattering and centrifugation.
We subsequently docked the plasmin on the simulated gold surface
to predict their interaction. The V-shaped plasmin could utilize its
Kringle domain and catalytic domain to contact the gold surface.
Our findings not only reveal the flexibility of plasmin structure but
also provide a guide for the design of a plasmin-gold nanoparticle.