Abstract: Folic acid (FA) is known to be an important
supplement to prevent neural tube defect (NTD) in pregnant women.
Similar to some commercial formulations, sodium bicarbonate
solution is used as a solvent for FA. This work uses the antisolvent
vapour precipitation (AVP), incorporating ethanol vapour as the
convective drying medium in place of air to produce branch-like
micro-structure FA particles. Interestingly, the dissolution rate of the
resultant particle is 2-3 times better than the particle produce from
conventional air drying due to the higher surface area of particles
produced. The higher dissolution rate could possibly improve the
delivery and absorption of FA in human body. This application could
potentially be extended to other commercial products, particularly in
less soluble drugs to improve its solubility.
Abstract: Medical imaging technology has experienced a
dramatic change in the last few years. Medical imaging refers to the
techniques and processes used to create images of the human body
(or parts thereof) for various clinical purposes such as medical
procedures and diagnosis or medical science including the study of
normal anatomy and function. With the growth of computers and
image technology, medical imaging has greatly influenced the
medical field. The diagnosis of a health problem is now highly
dependent on the quality and the credibility of the image analysis.
This paper deals with the various aspects and types of medical
imaging.
Abstract: Human movement in the real world provides
important information for developing human behaviour models and
simulations. However, it is difficult to assess ‘real’ human behaviour
since there is no established method available. As part of the AUNTSUE
(Accessibility and User Needs in Transport – Sustainable Urban
Environments) project, this research aimed to propose a method to
assess human movement and behaviour in crowded areas. The
method is based on the three major steps of video recording,
conceptual behavior modelling and video analysis. The focus is on
individual human movement and behaviour in normal situations
(panic situations are not considered) and the interactions between
individuals in localized areas. Emphasis is placed on gaining
knowledge of characteristics of human movement and behaviour in
the real world that can be modelled in the virtual environment.
Abstract: Hot aqueous and methanol extracts of the two selected
herbal medicines such are Vellarugu chooranam (V.C) and
Amukkirai Chooranam (A.C) were examined for total phenolic and
flavonoid contents and in vitro antioxidant activity using four
different methods. The total phenolic and flavonoid contents in
methanol extract of V.C were found to be higher (44.41±1.26mg
GAE/g; 174.44±9.32mg QE/g) than in the methanol extract of A.C
(20.56±0.67mg GAE/g; 7.21±0.85mg QE/g). Hot methanol and
aqueous extracts of both medicines showed low antioxidant activity
in DPPH, ABTS, and FRAP methods and Iron chelating activity not
found at highest possible concentration. V.C contains higher
concentrations of total phenolic and flavonoid contents than A.C and
can also exert greater antioxidant activity than A.C, although the
activities demonstrated were lower than the positive control Trolox.
The in vitro antioxidant activity was not related with the total
phenolic and flavonoid contents of the methanol and aqueous extracts
of both herbal medicines (A.C and V.C).
Abstract: This research aims to investigate callus induction,
somatic embryogenesis and indirect plant regeneration of Crassula
ovata (Mill.) Druce – the famous ornamental plant. Experiment no.1:
Callus induction was obtained from leaf and stem explants on
Murashige and Skoog (MS) medium supplemented with various plant
growth regulators (PGRs). Effects of different PGRs, plant
regeneration and subsequent plantlet conversion were also assessed.
Indirect plant regeneration was achieved from the callus of stem
explants by the addition of 1.5 mg/L Kinetin (KN) alone. Best shoot
induction was achieved (6.5 shoots/per explant) after 60 days. For
successful rooting, regenerated plantlets were sub-cultured on the
same MS media supplemented with 1.5 mg/L KN alone. The rooted
plantlets were acclimatized and the survival rate was 90%.
Experiment no.2: Results revealed that 0.5 mg/L 2,4-D alone and in
combination with 1.0 mg/L 6-Benzyladenine (BA) gave 89.8% callus
from the stem explants as compared to leaf explants. Callus
proliferation and somatic embryo formation were also evaluated by
‘Double Staining Method’ and different stages of somatic
embryogenesis were revealed by scanning electron microscope. Full
Strength MS medium produced the highest number (49.6%) of
cotyledonary stage somatic embryos (SEs). Mature cotyledonary
stage SEs developed into plantlets after 12 weeks of culture. Wellrooted
plantlets were successfully acclimatized at the survival rate of
85%. Indirectly regenerated plants did not show any detectable
variation in morphological and growth characteristics when
compared with the donor plant.
Abstract: This study proposes the transformation of nonlinear
Magnetic Levitation System into linear one, via state and feedback
transformations using explicit algorithm. This algorithm allows
computing explicitly the linearizing state coordinates and feedback
for any nonlinear control system, which is feedback linearizable,
without solving the Partial Differential Equations. The algorithm is
performed using a maximum of N-1 steps where N being the
dimension of the system.
Abstract: In MANET, mobile nodes communicate with each
other using the wireless channel where transmission takes place with
significant interference. The wireless medium used in MANET is a
shared resource used by all the nodes available in MANET. Packet
reserving is one important resource management scheme which
controls the allocation of bandwidth among multiple flows through
node cooperation in MANET. This paper proposes packet reserving
and clogging control via Routing Aware Packet Reserving (RAPR)
framework in MANET. It mainly focuses the end-to-end routing
condition with maximal throughput. RAPR is complimentary system
where the packet reserving utilizes local routing information
available in each node. Path setup in RAPR estimates the security
level of the system, and symbolizes the end-to-end routing by
controlling the clogging. RAPR reaches the packet to the destination
with high probability ratio and minimal delay count. The standard
performance measures such as network security level,
communication overhead, end-to-end throughput, resource utilization
efficiency and delay measure are considered in this work. The results
reveals that the proposed packet reservation and clogging control via
Routing Aware Packet Reserving (RAPR) framework performs well
for the above said performance measures compare to the existing
methods.
Abstract: Recent concerns about the value of teaching cursive
handwriting in the classroom are based on the belief that cursive
handwriting or penmanship is an outdated and unnecessary skill in
today’s online world. The discussion of this issue begins with a
description of current initiatives to eliminate handwriting instruction
in schools. This is followed by a brief history of cursive writing
through the ages. Next considered is a description of its benefits as a
preliminary process for younger children as compared with
immediate instruction in keyboarding, particularly in the areas of
vision, cognition, motor skills and automatic fluency. Also
considered, is cursive’s companion, paper itself, and the impact of a
paperless, “screen and keyboard” environment. The discussion
concludes with a consideration of the unique contributions of cursive
and keyboarding as written forms of communication, along with their
respective surfaces, paper and screen. Finally, an assessment of the
practical utility of each skill is followed by an informal assessment of
what is lost and what remains as we move from a predominantly
paper and pen world of handwriting to texting and keyboarding in an
environment of screens.
Abstract: In this paper the effect of wall waviness of side walls
in a two-dimensional wavy enclosure is numerically investigated.
Two vertical wavy walls and straight top wall are kept isothermal and
the bottom wall temperature is higher and spatially varying with
cosinusoidal temperature distribution. A computational code based on
Finite-volume approach is used to solve governing equations and
SIMPLE method is used for pressure velocity coupling. Test is
performed for several different numbers of undulations. The Prandtl
number was kept constant and the Ra number denotes that the flow is
laminar. Temperature and velocity fields are determined. Therefore,
according to the obtained results a correlation is proposed for average
Nusselt number as a function of number of side wall waves. The
results indicate that the Nusselt number is highly affected by number
of waves and increasing it decreases the wavy walls Nusselt number;
although the Nusselt number is not highly affected by surface
waviness when the number of undulations is below one.
Abstract: Age ratings are very helpful in providing parents with
relevant information for the purchase and use of digital technologies
by the children; this is why the non-definition of age ratings for the
use of ICTs by children in schools is a major concern; and this
problem serves as a motivation for this study whose aim is to
examine the factors affecting the perceptions of educators on the
learners’ youngest age for the introduction of ICTs in schools. This
aim is achieved through two types of research objectives: the
identification and design of theories and models on age ratings, and
the empirical testing of such theories and models in a survey of
educators from the Camperdown district of the South African
KwaZulu-Natal province. A questionnaire is used for the collection
of the data of this survey whose validity and reliability is checked in
SPSS prior to its descriptive and correlative quantitative analysis. The
main hypothesis supporting this research is the association between
the demographics of educators, their personality, and their
perceptions on the learners’ youngest age for the introduction of ICTs
in schools; as claimed by existing research; except that the present
study looks at personality from three dimensions: self-actualized
personalities, fully functioning personalities, and healthy
personalities. This hypothesis was fully confirmed by the empirical
study conducted by this research except for the demographic factor
where only the educators’ grade or class was found to be associated
with the personality of educators.
Abstract: reliability-based methodology for the assessment
and evaluation of reinforced concrete (R/C) structural elements of
concrete structures is presented herein. The results of the reliability
analysis and assessment for R/C structural elements were verified by
the results obtained through deterministic methods. The outcomes of
the reliability-based analysis were compared against currently
adopted safety limits that are incorporated in the reliability indices
β’s, according to international standards and codes. The methodology
is based on probabilistic analysis using reliability concepts and
statistics of the main random variables that are relevant to the subject
matter, and for which they are to be used in the performance-function
equation(s) associated with the structural elements under study.
These methodology techniques can result in reliability index β, which
is commonly known as the reliability index or reliability measure
value that can be utilized to assess and evaluate the safety, human
risk, and functionality of the structural component. Also, these
methods can result in revised partial safety factor values for certain
target reliability indices that can be used for the purpose of
redesigning the R/C elements of the building and in which they could
assist in considering some other remedial actions to improve the
safety and functionality of the member.
Abstract: Innovations not only contribute to competitiveness of
the company but have also positive effects on revenues. On average,
product innovations account to 14 percent of companies’ sales.
Innovation management has substantially changed during the last
decade, because of growing reliance on external partners. As a
consequence, a new task for purchasing arises, as firms need to
understand which suppliers actually do have high potential
contributing to the innovativeness of the firm and which do not.
Proper organization of the purchasing function is important since
for the majority of manufacturing companies deal with substantial
material costs which pass through the purchasing function. In the past
the purchasing function was largely seen as a transaction-oriented,
clerical function but today purchasing is the intermediate with supply
chain partners contributing to innovations, be it product or process
innovations. Therefore, purchasing function has to be organized
differently to enable firm innovation potential.
However, innovations are inherently risky. There are behavioral
risk (that some partner will take advantage of the other party),
technological risk in terms of complexity of products and processes
of manufacturing and incoming materials and finally market risks,
which in fact judge the value of the innovation. These risks are
investigated in this work. Specifically, technological risks which deal
with complexity of the products, and processes will be investigated
more thoroughly. Buying components or such high edge technologies
necessities careful investigation of technical features and therefore is
usually conducted by a team of experts. Therefore it is hypothesized
that higher the technological risk, higher will be the centralization of
the purchasing function as an interface with other supply chain
members.
Main contribution of this research lies is in the fact that analysis
was performed on a large data set of 1493 companies, from 25
countries collected in the GMRG 4 survey. Most analyses of
purchasing function are done by case study analysis of innovative
firms. Therefore this study contributes with empirical evaluations that
can be generalized.
Abstract: In the culture of Thailand, the Yak serve as a mediated
icon representing strength, power, and mystical protection not only
for the Buddha, but for population of worshipers. Originating from
the forests of China, the Yak continues to stand guard at the gates of
Buddhist temples. The Yak represents Thai culture in the hearts of
Thai people. This paper presents a qualitative study regarding the
curious mix of media, culture, and religion that projects the Yak of
Thailand as a larger than life message throughout the political,
cultural, and religious spheres. The gate guardians, or gods as they
are sometimes called, appear throughout the religious temples of
Asian cultures. However, the Asian cultures demonstrate differences
in artistic renditions (or presentations) of such sentinels. Thailand
gate guards (the Yak) stand in front of many Buddhist temples, and
these iconic figures display unique features with varied symbolic
significance. The temple (or wat), plays a vital role in every
community; and, for many people, Thailand’s temples are the
country’s most endearing sights. The authors applied folknography as
a methodology to illustrate the importance of the Thai Yak in serving
as meaningful icons that transcend not only time, but the culture,
religion, and mass media. The Yak represents mythical, religious,
artistic, cultural, and militaristic significance for the Thai people.
Data collection included interviews, focus groups, and natural
observations. This paper summarizes the perceptions of the Thai
people concerning their gate sentries and the relationship,
communication, connection, and the enduring respect that Thai
people hold for their guardians of the gates.
Abstract: In this study, we develop a performance evaluation
model based on a multi-attribute utility approach aiming at reaching
the sustainable banking (SB) status. This model is built accounting
for various banks’ stakeholders in a win-win paradigm. In addition, it
offers the opportunity for adopting a global measure of performance
as an indication of a bank’s sustainability degree. This measure is
referred to as banking sustainability performance index (BSPI). This
index may constitute a basis for ranking banks. Moreover, it may
constitute a bridge between the assessment types of financial and
extra-financial rating agencies. A real application is performed on
three French banks.
Abstract: The research focus on study, analyze and design the
model of the infrastructure and computer networks for distance
education, online learning via new media, e-learning and blended
learning. The collected information from study and analyze process
that information was evaluated by the index of item objective
congruence (IOC) by 9 specialists to design model. The results of
evaluate the model with the mean and standard deviation by the
sample of 9 specialists value is 3.85. The results showed that the
infrastructure and computer networks are designed to be appropriate
to a great extent appropriate to a great extent.
Abstract: The main aim of this research was to investigate the
perspectives of English language teachers and learners on the effect
of test techniques on reading comprehension, test performance and
assessment. The research has also aimed at finding the differences
between teacher and learner perspectives, specifying the test
techniques which have the highest effect, investigating the other
factors affecting reading comprehension, and comparing the results
with the similar studies. In order to achieve these objectives,
perspectives and findings of different researchers were reviewed, two
different questionnaires were prepared to collect data for the
perspectives of teachers and learners, the questionnaires were applied
to 26 learners and 8 teachers from the University of Batna (Algeria),
and quantitative and qualitative data analysis of the results were
done. The results and analysis of the results show that different test
techniques affect reading comprehension, test performance and
assessment at different percentages rates.
Abstract: Health analytics (HA) is used in healthcare systems
for effective decision making, management and planning of
healthcare and related activities. However, user resistances, unique
position of medical data content and structure (including
heterogeneous and unstructured data) and impromptu HA projects
have held up the progress in HA applications. Notably, the accuracy
of outcomes depends on the skills and the domain knowledge of the
data analyst working on the healthcare data. Success of HA depends
on having a sound process model, effective project management and
availability of supporting tools. Thus, to overcome these challenges
through an effective process model, we propose a HA process model
with features from rational unified process (RUP) model and agile
methodology.
Abstract: This paper is concerning the issues of behaviour of
lightweight expanded clay aggregates concrete exposed to high
temperature. Lightweight aggregates from expanded clay are
produced by firing of row material up to temperature 1050°C.
Lightweight aggregates have suitable properties in terms of volume
stability, when exposed to temperatures up to 1050°C, which could
indicate their suitability for construction applications with higher risk
of fire. The test samples were exposed to heat by using the standard
temperature-time curve ISO 834. Negative changes in resulting
mechanical properties, such as compressive strength, tensile strength,
and flexural strength were evaluated. Also visual evaluation of the
specimen was performed. On specimen exposed to excessive heat, an
explosive spalling could be observed, due to evaporation of
considerable amount of unbounded water from the inner structure of
the concrete.
Abstract: Web-based Cognitive Writing Instruction (WeCWI) is
a hybrid e-framework for the development of a web-based instruction
(WBI), which contributes towards instructional design and language
development. WeCWI divides its contribution in instructional design
into macro and micro perspectives. In macro perspective, being a 21st
century educator by disseminating knowledge and sharing ideas with
the in-class and global learners is initiated. By leveraging the virtue
of technology, WeCWI aims to transform an educator into an
aggregator, curator, publisher, social networker and ultimately, a
web-based instructor. Since the most notable contribution of
integrating technology is being a tool of teaching as well as a
stimulus for learning, WeCWI focuses on the use of contemporary
web tools based on the multiple roles played by the 21st century
educator. The micro perspective in instructional design draws
attention to the pedagogical approaches focusing on three main
aspects: reading, discussion, and writing. With the effective use of
pedagogical approaches through free reading and enterprises,
technology adds new dimensions and expands the boundaries of
learning capacity. Lastly, WeCWI also imparts the fundamental
theories and models for web-based instructors’ awareness such as
interactionist theory, cognitive information processing (CIP) theory,
computer-mediated communication (CMC), e-learning interactionalbased
model, inquiry models, sensory mind model, and leaning styles
model.
Abstract: Immunomodulators are substances that alter immune
system via dynamic regulation of messenger molecules. It can be
divided into immunostimulant and immunosuppressant. It can help to
increase immunity of people with a low immune system, and also can
help to normalize an overactive immune system. Aim of this study is
to investigate the effects of in vitro exposure to low and high doses of
several immunomodulators which include caffeine, kaloba and
quercetin on antigen-stimulated whole blood culture cytokine
production. Whole blood samples were taken from 5 healthy males
(age: 32 ± 12 years; weight: 75.7 ± 6.1 kg; BMI: 24.3 ± 1.5 kg/m2)
following an overnight fast with no vigorous activity during the
preceding 24 h. The whole blood was then stimulated with 50 μl of
100 x diluted Pediacel vaccine and low or high dose of
immunomodulators in the culture plate. After 20 h incubation (5%
CO2, 37°C), it was analysed using the Evidence Investigator to
determine the production of cytokines including IL-2, IL-4, IL-10,
IFN-γ, and IL-1α. Caffeine and quercetin showed a tendency towards
decrease cytokine production as the doses were increased. On the
other hand, an upward trend was evident with kaloba, where a high
dose of kaloba seemed to increase the cytokine production. In
conclusion, we found that caffeine and quercetin have potential as
immunosuppressant and kaloba as immunostimulant.