Abstract: This article demonstrated development of
controlled release system of an NSAID drug, Diclofenac
sodium employing different ratios of Ethyl cellulose.
Diclofenac sodium and ethyl cellulose in different proportions
were processed by microencapsulation based on phase
separation technique to formulate microcapsules. The
prepared microcapsules were then compressed into tablets to
obtain controlled release oral formulations. In-vitro evaluation
was performed by dissolution test of each preparation was
conducted in 900 ml of phosphate buffer solution of pH 7.2
maintained at 37 ± 0.5 °C and stirred at 50 rpm. At predetermined
time intervals (0, 0.5, 1.0, 1.5, 2, 3, 4, 6, 8, 10, 12,
16, 20 and 24 hrs). The drug concentration in the collected
samples was determined by UV spectrophotometer at 276 nm.
The physical characteristics of diclofenac sodium
microcapsules were according to accepted range. These were
off-white, free flowing and spherical in shape. The release
profile of diclofenac sodium from microcapsules was found to
be directly proportional to the proportion of ethylcellulose and
coat thickness. The in-vitro release pattern showed that with
ratio of 1:1 and 1:2 (drug: polymer), the percentage release of
drug at first hour was 16.91 and 11.52 %, respectively as
compared to 1:3 which is only 6.87 % with in this time. The
release mechanism followed higuchi model for its release
pattern. Tablet Formulation (F2) of present study was found
comparable in release profile the marketed brand Phlogin-SR,
microcapsules showed an extended release beyond 24 h.
Further, a good correlation was found between drug release
and proportion of ethylcellulose in the microcapsules.
Microencapsulation based on coacervation found as good
technique to control release of diclofenac sodium for making
the controlled release formulations.
Abstract: Three-dimensional geometric models have been used
to present architectural and engineering works, showing their final
configuration. When the clarification of a detail or the constitution of
a construction step in needed, these models are not appropriate. They
do not allow the observation of the construction progress of a
building. Models that could present dynamically changes of the
building geometry are a good support to the elaboration of projects.
Techniques of geometric modeling and virtual reality were used to
obtain models that could visually simulate the construction activity.
The applications explain the construction work of a cavity wall and a
bridge. These models allow the visualization of the physical
progression of the work following a planned construction sequence,
the observation of details of the form of every component of the
works and support the study of the type and method of operation of
the equipment applied in the construction. These models presented
distinct advantage as educational aids in first-degree courses in Civil
Engineering. The use of Virtual Reality techniques in the
development of educational applications brings new perspectives to
the teaching of subjects related to the field of civil construction.
Abstract: The design of a landing gear is one of the fundamental aspects of aircraft design. The need for a light weight, high strength, and stiffness characteristics coupled with techno economic feasibility are a key to the acceptability of any landing gear construction. In this paper, an approach for analyzing two different designed landing gears for an unmanned aircraft vehicle (UAV) using advanced CAE techniques will be applied. Different landing conditions have been considered for both models. The maximum principle stresses for each model along with the factor of safety are calculated for every loading condition. A conclusion is drawing about better geometry.
Abstract: This paper deals with modeling and parameter
identification of nonlinear systems described by Hammerstein model
having Piecewise nonlinear characteristics such as Dead-zone
nonlinearity characteristic. The simultaneous use of both an easy
decomposition technique and the triangular basis functions leads to a
particular form of Hammerstein model. The approximation by using
Triangular basis functions for the description of the static nonlinear
block conducts to a linear regressor model, so that least squares
techniques can be used for the parameter estimation. Singular Values
Decomposition (SVD) technique has been applied to separate the
coupled parameters. The proposed approach has been efficiently
tested on academic examples of simulation.
Abstract: The Romanian government has been making
significant attempts to make its services and information available on
the Internet. According to the UN e-government survey conducted in
2008, Romania comes under mid range countries by utilization of egovernment
(percent of utilization 41%). Romania-s national portal
www.e-guvernare.ro aims at progressively making all services and
information accessible through the portal. However, the success of
these efforts depends, to a great extent, on how well the targeted
users for such services, citizens in general, make use of them. For
this reason, the purpose of the presented study was to identify what
factors could affect the citizens' adoption of e-government services.
The study is an extension of the Technology Acceptance Model. The
proposed model was validated using data collected from 481 citizens.
The results provided substantial support for all proposed hypotheses
and showed the significance of the extended constructs.
Abstract: A key element of many distribution systems is the
routing and scheduling of vehicles servicing a set of customers. A
wide variety of exact and approximate algorithms have been
proposed for solving the vehicle routing problems (VRP). Exact
algorithms can only solve relatively small problems of VRP, which is
classified as NP-Hard. Several approximate algorithms have proven
successful in finding a feasible solution not necessarily optimum.
Although different parts of the problem are stochastic in nature; yet,
limited work relevant to the application of discrete event system
simulation has addressed the problem. Presented here is optimization
using simulation of VRP; where, a simplified problem has been
developed in the ExtendSimTM simulation environment; where,
ExtendSimTM evolutionary optimizer is used to minimize the total
transportation cost of the problem. Results obtained from the model
are very satisfactory. Further complexities of the problem are
proposed for consideration in the future.
Abstract: The drastic increase in the usage of SMS technology
has led service providers to seek for a solution that enable users of
mobile devices to access services through SMSs. This has resulted in
the proposal of solutions towards SMS-based service invocation in
service oriented environments. However, the dynamic nature of
service-oriented environments coupled with sudden load peaks
generated by service request, poses performance challenges to
infrastructures for supporting SMS-based service invocation. To
address this problem we adopt load balancing techniques. A load
balancing model with adaptive load balancing and load monitoring
mechanisms as its key constructs is proposed. The load balancing
model then led to realization of Least Loaded Load Balancing
Framework (LLLBF). Evaluation of LLLBF benchmarked with round
robin (RR) scheme on the queuing approach showed LLLBF
outperformed RR in terms of response time and throughput.
However, LLLBF achieved better result in the cost of high
processing power.
Abstract: This study aims to investigate empirically the valuerelevance
of accounting information to domestic investors in Tehran
stock exchange from 1999 to 2006. During the present research
impacts of two factors, including positive vs. negative earnings and
the firm size are considered as well. The authors used earnings per
share and annual change of earnings per share as the income
statement indices, and book value of equity per share as the balance
sheet index. Return and Price models through regression analysis are
deployed in order to test the research hypothesis. Results depicted
that accounting information is value-relevance to domestic investors
in Tehran Stock Exchange according to both studied models.
However, income statement information has more value-relevance
than the balance sheet information. Furthermore, positive vs. negative
earnings and firm size seems to have significant impact on valuerelevance
of accounting information.
Abstract: The aim of the study was to investigate the possible
use of commercial Computational Fluid Dynamics (CFD) software in
the design process of a domestic gas boiler. Because of the limited
computational resources some simplifications had to be made in
order to contribute to the design in a reasonable timescale.
The porous media model was used in order to simulate the
influence of the pressure drop characteristic of particular elements of
a heat transfer system on the water-flow distribution in the system.
Further, a combination of CFD analyses and spread sheet
calculations was used in order to solve the flow distribution problem.
Abstract: Super-resolution is nowadays used for a high-resolution
image produced from several low-resolution noisy frames. In
this work, we consider the problem of high-quality interpolation of a
single noise-free image. Such images may come from different sources,
i.e., they may be frames of videos, individual pictures, etc. On
the other hand, in the encoder we apply a downsampling via
bidimen-sional interpolation of each frame, and in the decoder we
apply a upsampling by which we restore the original size of the
image. If the compression ratio is very high, then we use a
convolutive mask that restores the edges, eliminating the blur.
Finally, both, the encoder and the complete decoder are implemented
on General-Purpose computation on Graphics Processing Units
(GPGPU) cards. In fact, the mentioned mask is coded inside texture
memory of a GPGPU.
Abstract: This paper proposes a system to extract images from web pages and then detect the skin color regions of these images. As part of the proposed system, using BandObject control, we built a Tool bar named 'Filter Tool Bar (FTB)' by modifying the Pavel Zolnikov implementation. The Yahoo! Team provides us with the Yahoo! SDK API, which also supports image search and is really useful. In the proposed system, we introduced three new methods for extracting images from the web pages (after loading the web page by using the proposed FTB, before loading the web page physically from the localhost, and before loading the web page from any server). These methods overcome the drawback of the regular expressions method for extracting images suggested by Ilan Assayag. The second part of the proposed system is concerned with the detection of the skin color regions of the extracted images. So, we studied two famous skin color detection techniques. The first technique is based on the RGB color space and the second technique is based on YUV and YIQ color spaces. We modified the second technique to overcome the failure of detecting complex image's background by using the saturation parameter to obtain an accurate skin detection results. The performance evaluation of the efficiency of the proposed system in extracting images before and after loading the web page from localhost or any server in terms of the number of extracted images is presented. Finally, the results of comparing the two skin detection techniques in terms of the number of pixels detected are presented.
Abstract: An image compression method has been developed
using fuzzy edge image utilizing the basic Block Truncation Coding
(BTC) algorithm. The fuzzy edge image has been validated with
classical edge detectors on the basis of the results of the well-known
Canny edge detector prior to applying to the proposed method. The
bit plane generated by the conventional BTC method is replaced with
the fuzzy bit plane generated by the logical OR operation between
the fuzzy edge image and the corresponding conventional BTC bit
plane. The input image is encoded with the block mean and standard
deviation and the fuzzy bit plane. The proposed method has been
tested with test images of 8 bits/pixel and size 512×512 and found to
be superior with better Peak Signal to Noise Ratio (PSNR) when
compared to the conventional BTC, and adaptive bit plane selection
BTC (ABTC) methods. The raggedness and jagged appearance, and
the ringing artifacts at sharp edges are greatly reduced in
reconstructed images by the proposed method with the fuzzy bit
plane.
Abstract: Along with the progress of our information society,
various risks are becoming increasingly common, causing multiple social problems. For this reason, risk communications for
establishing consensus among stakeholders who have different
priorities have become important. However, it is not always easy for the decision makers to agree on measures to reduce risks based on
opposing concepts, such as security, privacy and cost. Therefore, we previously developed and proposed the “Multiple Risk Communicator" (MRC) with the following functions: (1) modeling
the support role of the risk specialist, (2) an optimization engine, and (3) displaying the computed results. In this paper, MRC program
version 1.0 is applied to the personal information leakage problem. The application process and validation of the results are discussed.
Abstract: In this paper, we study the pulsatile flow of blood through stenotic arteries. The inner layer of arterial walls is modeled as a porous medium and human blood is assumed as an incompressible fluid. A numerical algorithm based on the finite element method is developed to simulate the blood flow through both the lumen region and the porous wall. The algorithm is then applied to study the flow behaviour and to investigate the significance of the non-Newtonian effect.
Abstract: A lot of research has been done in the past decade in the field of audio content analysis for extracting various information from audio signal. One such significant information is the "perceived mood" or the "emotions" related to a music or audio clip. This information is extremely useful in applications like creating or adapting the play-list based on the mood of the listener. This information could also be helpful in better classification of the music database. In this paper we have presented a method to classify music not just based on the meta-data of the audio clip but also include the "mood" factor to help improve the music classification. We propose an automated and efficient way of classifying music samples based on the mood detection from the audio data. We in particular try to classify the music based on mood for Indian bollywood music. The proposed method tries to address the following problem statement: Genre information (usually part of the audio meta-data) alone does not help in better music classification. For example the acoustic version of the song "nothing else matters by Metallica" can be classified as melody music and thereby a person in relaxing or chill out mood might want to listen to this track. But more often than not this track is associated with metal / heavy rock genre and if a listener classified his play-list based on the genre information alone for his current mood, the user shall miss out on listening to this track. Currently methods exist to detect mood in western or similar kind of music. Our paper tries to solve the issue for Indian bollywood music from an Indian cultural context
Abstract: In this paper we propose a segmentation system for unconstrained Arabic online handwriting. An essential problem addressed by analytical-based word recognition system. The system is composed of two-stages the first is a newly special designed hidden Markov model (HMM) and the second is a rules based stage. In our system, handwritten words are broken up into characters by simultaneous segmentation-recognition using HMMs of unique design trained using online features most of which are novel. The HMM output characters boundaries represent the proposed segmentation points (PSP) which are then validated by rules-based post stage without any contextual information help to solve different segmentation errors. The HMM has been designed and tested using a self collected dataset (OHASD) [1]. Most errors cases are cured and remarkable segmentation enhancement is achieved. Very promising word and character segmentation rates are obtained regarding the unconstrained Arabic handwriting difficulty and not using context help.
Abstract: The purpose of this paper is to examine the financing
practices of SMEs in Libya in two different phases of business life
cycle: start-up and matured stages. Moreover, SMEs- accessing bank
loan issues is also identified. The study was conducted by taking into
account the aspect of demand. The findings are based on a sample of
76 SMEs in Libya through the adoption of questionnaires. The results
have pinpointed several things- evidently, SMEs use informal
financing sources which prefer personal savings; SME owners are
willing to apply for bank loan, that the most pressing problem has
been identified, not to apply bank loan is loan with interest (religion
factor).
Abstract: Exposure to ambient air pollution has been linked to a
number of health outcomes, starting from modest transient changes in
the respiratory tract and impaired pulmonary function, continuing to
restrict activity/reduce performance and to the increase emergency
rooms visits, hospital admissions or mortality. The increase of
allergenic symptoms has been associated with air contaminants such
as ozone, particulate matter, fungal spores and pollen.
Considering the potential relevance of crossed effects of nonbiological
pollutants and airborne pollens and fungal spores on
allergy worsening, the aim of this work was to evaluate the influence
of non-biological pollutants (O3 and PM10) and meteorological
parameters on the concentrations of pollen and fungal spores using
multiple linear regressions.
The data considered in this study were collected in Oporto which
is the second largest Portuguese city, located in the North. Daily
mean of O3, PM10, pollen and fungal spore concentrations,
temperature, relative humidity, precipitation, wind velocity, pollen
and fungal spore concentrations, for 2003, 2004 and 2005 were
considered. Results showed that the 90th percentile of the adjusted
coefficient of determination, P90 (R2aj), of the multiple regressions
varied from 0.613 to 0.916 for pollen and from 0.275 to 0.512 for
fungal spores. O3 and PM10 showed to have some influence on the
biological pollutants. Among the meteorological parameters
analysed, temperature was the one that most influenced the pollen
and fungal spores airborne concentrations. Relative humidity also
showed to have some influence on the fungal spore dispersion.
Nevertheless, the models for each pollen and fungal spore were
different depending on the analysed period, which means that the
correlations identified as statistically significant can not be, even so,
consistent enough.
Abstract: When the shock front (SF) hits the central electrode
axis of plasma focus device, a reflected shock wave moves radially
outwards. The current sheath (CS) results from ionization of filled
gas between two electrodes continues to compress inwards until it
hits the out-going reflected shock front. In this paper the Lagrangian
equations are solved for a parabolic shock trajectory yielding a first
and second approximation for the CS path. To determine the
accuracy of the approximation, the same problem is solved for a
straight shock.
Abstract: Accurate modeling of high speed RLC interconnects
has become a necessity to address signal integrity issues in current
VLSI design. To accurately model a dispersive system of interconnects
at higher frequencies; a full-wave analysis is required.
However, conventional circuit simulation of interconnects with full
wave models is extremely CPU expensive. We present an algorithm
for reducing large VLSI circuits to much smaller ones with similar
input-output behavior. A key feature of our method, called Frequency
Shift Technique, is that it is capable of reducing linear time-varying
systems. This enables it to capture frequency-translation and sampling
behavior, important in communication subsystems such as mixers,
RF components and switched-capacitor filters. Reduction is obtained
by projecting the original system described by linear differential
equations into a lower dimension. Experiments have been carried out
using Cadence Design Simulator cwhich indicates that the proposed
technique achieves more % reduction with less CPU time than the
other model order reduction techniques existing in literature. We
also present applications to RF circuit subsystems, obtaining size
reductions and evaluation speedups of orders of magnitude with
insignificant loss of accuracy.