Abstract: This study aimed to determine the possible protective effects of L‐carnitine against gentamicin‐induced nephrotoxicity. Forty male albino rats were divided into 4 groups (10 rats each); Group 1: normal control, group 2: induced nephrotoxicity (gentamicin 50 mg/kg/day S.C; 8 days), group 3: treated with L‐ carnitine (40 mg/kg/d SC for 12 days) and group 4: treated with L‐ carnitine 4 days before and for 8 days in concomitant with gentamicin. Gentamicin‐induced nephrotoxicity (group 2): caused significant increase in serum urea, creatinine, urinary N‐acetyl‐B‐D‐ glucosaminidase (NAG), gamma glutamyl transpeptidase (GGT), urinary total protein and kidney tissue malondialdehyde (MDA) with significant decrease in serum superoxide dismutase (SOD), serum catalase and creatinine clearance and marked tubular necrosis in the proximal convoluted tubules with interruption in the basement membrane around the necrotic tubule compared to the normal control group. L‐carnitine 4 days before and for 8 days in concomitant with gentamicin (group 4) offered marked decrease in serum urea, serum creatinine, urinary NAG, urinary GGT, urinary proteins and kidney tissue MDA, with marked increase in serum SOD, serum catalase and creatinine clearance with marked improvement in the tubular damage compared to gentamicin‐induced nephrotoxicity group. L‐carnitine administered for 12 days produced no change in the parameters mentioned above as compared to the normal control group. In conclusion: L‐carnitine could reduce most of the biochemical parameters and also improve the histopathological features of kidney asscociated with gentamicin induced‐nephrotoxicity.
Abstract: Out-migration is an important issue for Georgia as
well as since independence has loosed due to emigration one fifth of
its population. During Soviet time out-migration from USSR was
almost impossible and one of the most important instruments in
regulating population movement within the Soviet Union was the
system of compulsory residential registrations, so-called “propiska”.
Since independent here was not any regulation for migration from
Georgia. The majorities of Georgian migrants go abroad by tourist
visa and then overstay, becoming the irregular labor migrants. The
official statistics on migration published for this period was based on
the administrative system of population registration, were
insignificant in terms of numbers and did not represent the real scope
of these migration movements. This paper discusses the data quality
and methodology of migration statistics in Georgia and we are going
to answer the questions: what is the real reason of increasing
immigration flows according to the official numbers since 2000s?
Abstract: We report herein the development and preliminary mechanical characterization of fully-dense multi-wall carbon nanotube (MWCNT)-reinforced ceramics and glasses based on a completely new methodology termed High Shear Compaction (HSC). The tubes are introduced and bound to the matrix grains by aid of polymeric binders to form flexible green bodies which are sintered and densified by spark plasma sintering to unprecedentedly high densities of 100% of the pure-matrix value. The strategy was validated across a PyrexTM glass / MWCNT composite while no identifiable factors limit application to other types of matrices. Nondestructive evaluation, based on ultrasonics, of the dynamic mechanical properties of the materials including elastic, shear and bulk modulus as well as Poisson’s ratio showed optimum property improvement at 0.5 %wt tube loading while evidence of nanoscalespecific energy dissipative characteristics acting complementary to nanotube bridging and pull-out indicate a high potential in a wide range of reinforcing and multifunctional applications.
Abstract: The crude methanol extracts of five indigenous vegetables namely, Amarathus tricolor, Basella rubra L., Chochurus olitorius L., Ipomea batatas, and Momordica chuchinensis L., were examined for their phytochemical profile and antioxidant activity using 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical. The values for DPPH radical scavenging activity ranged from 7.6-89.53% with B. rubra and I. batatas having the lowest and highest values, respectively. The total flavonoid content of all five indigenous vegetables ranged from 74.65-277.3 mg quercetin equivalent per gram of dried vegetable material while the total phenolic content ranged from 1.93-6.15 mg gallic acid equivalent per gram dried material. Phytochemical screening revealed the presence of steroids, flavonoids, saponins, tannins, carbohydrates and reducing sugars, which may also be associated with the antioxidant activity shown by these indigenous vegetables.
Abstract: STRIM (Statistical Test Rule Induction Method) has been proposed as a method to effectively induct if-then rules from the decision table which is considered as a sample set obtained from the population of interest. Its usefulness has been confirmed by simulation experiments specifying rules in advance, and by comparison with conventional methods. However, scope for future development remains before STRIM can be applied to the analysis of real-world data sets. The first requirement is to determine the size of the dataset needed for inducting true rules, since finding statistically significant rules is the core of the method. The second is to examine the capacity of rule induction from datasets with contaminated attribute values created by missing data and noise, since real-world datasets usually contain such contaminated data. This paper examines the first problem theoretically, in connection with the rule length. The second problem is then examined in a simulation experiment, utilizing the critical size of dataset derived from the first step. The experimental results show that STRIM is highly robust in the analysis of datasets with contaminated attribute values, and hence is applicable to real-world data
Abstract: In the years followed independence, an economic
crisis and some conflicts led to the displacement of many people
inside Georgia. The growing poverty, unemployment, low income
and its unequal distribution limited access to basic social service have
had a clear direct impact on Georgian population dynamics and its
age-sex structure. Factors influencing the changing population age
structure and urbanization include mortality, fertility, migration and
expansion of urban. In this paper presents the main factors of
changing the distribution by urban and rural areas. How different are
the urban and rural age and sex structures? Does Georgia have the
same age-sex structure among their urban and rural populations since
1950s?
Abstract: This study was conducted to examine the effectiveness of Teaching Games For Understanding (TGFU) in improving the hockey tactical skills and state self-confidence among 16-year-old students. Two hundred fifty-nine (259) school students were selected for the study based on the intact sampling method. One class was used as the control group (Boys=60, Girls=70), while another as the treatment group (Boys=60, Girls=69) underwent intervention with TGFU in physical education class conducted twice a week for four weeks. The Games Performance Assessment Instrument was used to observe the hockey tactical skills and The State Self-Confidence Inventory was used to determine the state of self-confidence among the students. After four weeks, ANCOVA analysis indicated the treatment groups had significant improvement in hockey tactical skills with F (1, 118) =313.37, p
Abstract: Obesity and osteoporosis are the two diseases whose
increasing prevalence and high impact on the global morbidity and
mortality, during the two recent decades, have gained a status of
major health threats worldwide. Obesity purports to affect the bone
metabolism through complex mechanisms. Debated data on the
connection between the bone mineral density and fracture prevalence
in the obese patients are widely presented in literature. There is
evidence that the correlation of weight and fracture risk is sitespecific.
This study is aimed at determining the connection between
the bone mineral density (BMD) and trabecular bone score (TBS)
parameters in Ukrainian women suffering from obesity. We
examined 1025 40-89-year-old women, divided them into the groups
according to their body mass index: Group A included 360 women
with obesity whose BMI was ≥30 kg/m2, and Group B – 665 women
with no obesity and BMI of
Abstract: Supply chains are the backbone of trade and
commerce. Their logistics use different transport corridors on regular
basis for operational purpose. The international supply chain
transport corridors include different infrastructure elements (e.g.
weighbridge, package handling equipments, border clearance
authorities, and so on). This paper presents the use of multi-agent
systems (MAS) to model and simulate some aspects of transportation
corridors, and in particular the area of weighbridge resource
optimization for operational profit. An underlying multi-agent model
provides a means of modeling the relationships among stakeholders
in order to enable coordination in a transport corridor environment.
Simulations of the costs of container unloading, reloading, and
waiting time for queuing up tracks have been carried out using data
sets. Results of the simulation provide the potential guidance in
making decisions about optimal service resource allocation in a trade
corridor.
Abstract: Boiling process is characterized by the rapid
formation of vapour bubbles at the solid–liquid interface (nucleate
boiling) with pre-existing vapour or gas pockets. Computational fluid
dynamics (CFD) is an important tool to study bubble dynamics. In
the present study, CFD simulation has been carried out to determine
the bubble detachment diameter and its terminal velocity. Volume of
fluid method is used to model the bubble and the surrounding by
solving single set of momentum equations and tracking the volume
fraction of each of the fluids throughout the domain. In the
simulation, bubble is generated by allowing water-vapour to enter a
cylinder filled with liquid water through an inlet at the bottom. After
the bubble is fully formed, the bubble detaches from the surface and
rises up during which the bubble accelerates due to the net balance
between buoyancy force and viscous drag. Finally when these forces
exactly balance each other, it attains a constant terminal velocity. The
bubble detachment diameter and the terminal velocity of the bubble
are captured by the monitor function provided in FLUENT. The
detachment diameter and the terminal velocity obtained are compared
with the established results based on the shape of the bubble. A good
agreement is obtained between the results obtained from simulation
and the equations in comparison with the established results.
Abstract: We investigate experimentally and theoretically the
dynamics of a capacitive resonator under mixed frequency excitation
of two AC harmonic signals. The resonator is composed of a proof
mass suspended by two cantilever beams. Experimental
measurements are conducted using a laser Doppler Vibrometer to
reveal the interesting dynamics of the system when subjected to twosource
excitation. A nonlinear single-degree-of-freedom model is
used for the theoretical investigation. The results reveal combination
resonances of additive and subtractive type, which are shown to be
promising to increase the bandwidth of the resonator near primary
resonance frequency. Our results also demonstrate the ability to shift
the combination resonances to much lower or much higher frequency
ranges. We also demonstrate the dynamic pull-in instability under
mixed frequency excitation.
Abstract: Model transformation, as a pivotal aspect of Modeldriven
engineering, attracts more and more attentions both from
researchers and practitioners. Many domains (enterprise engineering,
software engineering, knowledge engineering, etc.) use model
transformation principles and practices to serve to their domain
specific problems; furthermore, model transformation could also be
used to fulfill the gap between different domains: by sharing and
exchanging knowledge. Since model transformation has been widely
used, there comes new requirement on it: effectively and efficiently
define the transformation process and reduce manual effort that
involved in. This paper presents an automatic model transformation
methodology based on semantic and syntactic comparisons, and
focuses particularly on granularity issue that existed in transformation
process. Comparing to the traditional model transformation
methodologies, this methodology serves to a general purpose: crossdomain
methodology. Semantic and syntactic checking
measurements are combined into a refined transformation process,
which solves the granularity issue. Moreover, semantic and syntactic
comparisons are supported by software tool; manual effort is replaced
in this way.
Abstract: Designing cost-efficient, secure network protocols for
Wireless Sensor Networks (WSNs) is a challenging problem because
sensors are resource-limited wireless devices. Security services such
as authentication and improved pairwise key establishment are
critical to high efficient networks with sensor nodes. For sensor
nodes to correspond securely with each other efficiently, usage of
cryptographic techniques is necessary. In this paper, two key
predistribution schemes that enable a mobile sink to establish a
secure data-communication link, on the fly, with any sensor nodes.
The intermediate nodes along the path to the sink are able to verify
the authenticity and integrity of the incoming packets using a
predicted value of the key generated by the sender’s essential power.
The proposed schemes are based on the pairwise key with the mobile
sink, our analytical results clearly show that our schemes perform
better in terms of network resilience to node capture than existing
schemes if used in wireless sensor networks with mobile sinks.
Abstract: This paper presents an approach for the classification of
an unstructured format description for identification of file formats.
The main contribution of this work is the employment of data mining
techniques to support file format selection with just the unstructured
text description that comprises the most important format features for
a particular organisation. Subsequently, the file format indentification
method employs file format classifier and associated configurations to
support digital preservation experts with an estimation of required file
format. Our goal is to make use of a format specification knowledge
base aggregated from a different Web sources in order to select file
format for a particular institution. Using the naive Bayes method,
the decision support system recommends to an expert, the file format
for his institution. The proposed methods facilitate the selection of
file format and the quality of a digital preservation process. The
presented approach is meant to facilitate decision making for the
preservation of digital content in libraries and archives using domain
expert knowledge and specifications of file formats. To facilitate
decision-making, the aggregated information about the file formats is
presented as a file format vocabulary that comprises most common
terms that are characteristic for all researched formats. The goal is to
suggest a particular file format based on this vocabulary for analysis
by an expert. The sample file format calculation and the calculation
results including probabilities are presented in the evaluation section.
Abstract: This paper presents a computational study of steady
state three dimensional very high turbulent flow and heat transfer
characteristics in a constant temperature-surfaced circular duct fitted
with 900 hemispherical inline baffles. The computations are based on
realizable k-ɛ model with standard wall function considering the
finite volume method, and the SIMPLE algorithm has been
implemented. Computational Study are carried out for Reynolds
number, Re ranging from 80000 to 120000, Prandtl Number, Pr of
0.73, Pitch Ratios, PR of 1,2,3,4,5 based on the hydraulic diameter of
the channel, hydrodynamic entry length, thermal entry length and the
test section. Ansys Fluent 15.0 software has been used to solve the
flow field. Study reveals that circular pipe having baffles has a higher
Nusselt number and friction factor compared to the smooth circular
pipe without baffles. Maximum Nusselt number and friction factor
are obtained for the PR=5 and PR=1 respectively. Nusselt number
increases while pitch ratio increases in the range of study; however,
friction factor also decreases up to PR 3 and after which it becomes
almost constant up to PR 5. Thermal enhancement factor increases
with increasing pitch ratio but with slightly decreasing Reynolds
number in the range of study and becomes almost constant at higher
Reynolds number. The computational results reveal that optimum
thermal enhancement factor of 900 inline hemispherical baffle is
about 1.23 for pitch ratio 5 at Reynolds number 120000.It also shows
that the optimum pitch ratio for which the baffles can be installed in
such very high turbulent flows should be 5. Results show that pitch
ratio and Reynolds number play an important role on both fluid flow
and heat transfer characteristics.
Abstract: By the evolvement in technology, the way of
expressing opinions switched direction to the digital world. The
domain of politics, as one of the hottest topics of opinion mining
research, merged together with the behavior analysis for affiliation
determination in texts, which constitutes the subject of this paper.
This study aims to classify the text in news/blogs either as
Republican or Democrat with the minimum number of features. As
an initial set, 68 features which 64 were constituted by Linguistic
Inquiry and Word Count (LIWC) features were tested against 14
benchmark classification algorithms. In the later experiments, the
dimensions of the feature vector reduced based on the 7 feature
selection algorithms. The results show that the “Decision Tree”,
“Rule Induction” and “M5 Rule” classifiers when used with “SVM”
and “IGR” feature selection algorithms performed the best up to
82.5% accuracy on a given dataset. Further tests on a single feature
and the linguistic based feature sets showed the similar results. The
feature “Function”, as an aggregate feature of the linguistic category,
was found as the most differentiating feature among the 68 features
with the accuracy of 81% in classifying articles either as Republican
or Democrat.
Abstract: In this work, the Ictalurus punctatus species estimated
available physical habitat is compared with the estimated physical
habitat for the same but modified river reach, with the aim of creating
a linear park, along a length of 5 500 m.
To determine the effect of ecological park construction, on
physical habitat of the Lerma river stretch of study, first, the available
habitat for the Ictalurus punctatus species was estimated through the
simulation of the physical habitat, by using surveying, hydraulics,
and habitat information gotten at the river reach in its actual situation.
Second, it was estimated the available habitat for the above species,
upon the simulation of the physical habitat through the proposed
modification for the ecological park creation. Third, it is presented a
comparison between both scenarios in terms of available habitat
estimated for Ictalurus punctatus species, concluding that in cases of
adult and spawning life stages, changes in the channel to create an
ecological park would produce a considerable loss of potentially
usable habitat (PUH), while in the case of the juvenile life stage PUH
remains virtually unchanged, and in the case of life stage fry the PUH
would increase due to the presence of velocities and depths of lesser
magnitude, due to the presence of minor flow rates and lower volume
of the wet channel.
It is expected that habitat modification for linear park construction
may produce the lack of Ictalurus punktatus species conservation at
the river reach of the study.
Abstract: A pilot field study was conducted at the Jagjeetpur
Municipal Sewage treatment plant situated in the Haridwar town in
Uttarakhand state, India. The objectives of the present study were to
study the effect of treated wastewater on the production of various
paddy varieties (Sharbati, PR-114, PB-1, Menaka, PB1121 and PB
1509) and the emission of GHG gases (CO2, CH4 and N2O) as
compared to the same varieties grown in the control plots irrigated
with fresh water. Of late, the concept of water footprint assessment
has emerged, which explains enumeration of various types of water
footprints of an agricultural entity from its production to processing
stages. Paddy, the most water demanding staple crop of Uttarakhand
state, displayed a high green water footprint value of 2474.12 m3/
Ton. Most of the wastewater irrigated varieties displayed up to 6%
increase in production, except Menaka and PB-1121, which showed a
reduction in production (6% and 3% respectively), due to pest and
insect infestation. The treated wastewater was observed to be rich in
Nitrogen (55.94 mg/ml Nitrate), Phosphorus (54.24 mg/ml) and
Potassium (9.78 mg/ml), thus rejuvenating the soil quality and not
requiring any external nutritional supplements. A Percentage increase
of GHG gases of irrigation with treated municipal wastewater as
compared to control plots was observed as 0.4% - 8.6% (CH4), 1.1%
- 9.2% (CO2), and 0.07% - 5.8% (N2O). The variety, Sharbati,
displayed maximum production (5.5 ton/ha) and emerged as the most
resistant variety against pests and insects. The emission values of
CH4, CO2 and N2O were 729.31 mg/m2/d, 322.10 mg/m2/d and
400.21 mg/m2/d in water stagnant condition.
This study highlighted a successful possibility of reuse of
wastewater for non-potable purposes offering the potential for
exploiting this resource that can replace or reduce the existing use of
fresh water sources in agriculture sector.
Abstract: The purpose of the study was to find out the effects of
Aquatic and Land plyometric training on selected physical variables
in intercollegiate male handball players. To achieve this purpose of
the study, forty five handball players of Sardar Vallabhbhai National
Institute of Technology, Surat, Gujarat were selected as players at
random and their age ranged between 18 to 21 years. The selected
players were divided into three equal groups of fifteen players each.
Group I underwent Aquatic plyometric training, Group II underwent
Land plyometric training and Group III Control group for three days
per week for twelve weeks. Control Group did not participate in any
special training programme apart from their regular activities as per
their curriculum. The following physical fitness variables namely
speed; leg explosive power and agility were selected as dependent
variables. All the players of three groups were tested on selected
dependent variables prior to and immediately after the training
programme. The analysis of covariance was used to analyze the
significant difference, if any among the groups. Since, three groups
were compared, whenever the obtained ‘F’ ratio for adjusted posttest
was found to be significant, the Scheffe’s test to find out the paired
mean differences, if any. The 0.05 level of confidence was fixed as
the level of significance to test the ‘F’ ratio obtained by the analysis
of covariance, which was considered as an appropriate. The result of
the study indicates due to Aquatic and Land plyometric training on
speed, explosive power, and agility has been improved significantly.
Abstract: The venture capital becomes more and more advanced
and effective source of the innovation project financing, connected
with a high-risk level. In the developed countries, it plays a key role
in transforming innovation projects into successful businesses and
creating the prosperity of the modern economy. In Russia, there are
many necessary preconditions for creation of the effective venture
investment system: the network of the public institutes for innovation
financing operates; there is a significant number of the small and
medium-sized enterprises, capable to sell production with good
market potential. However, the current system does not confirm the
necessary level of efficiency in practice that can be substantially
explained by the absence of the accurate plan of action to form the
national venture model and by the lack of experience of successful
venture deals with profitable exits in Russian economy. This paper
studies the influence of various factors on the venture industry
development by the example of the IT-sector in Russia. The choice of
the sector is based on the fact, that this segment is the main driver of
the venture capital market growth in Russia, and the necessary set of
data exists. The size of investment of the second round is used as the
dependent variable. To analyse the influence of the previous round,
such determinant as the volume of the previous (first) round
investments is used. There is also used a dummy variable in
regression to examine that the participation of an investor with high
reputation and experience in the previous round can influence the size
of the next investment round. The regression analysis of short-term
interrelations between studied variables reveals prevailing influence
of the volume of the first round investments on the venture
investments volume of the second round. The most important
determinant of the value of the second-round investment is the value
of first–round investment, so it means that the most competitive on
the Russian market are the start-up teams that can attract more money
on the start, and the target market growth is not the factor of crucial
importance. This supports the point of view that VC in Russia is
driven by endogenous factors and not by exogenous ones that are
based on global market growth.