Abstract: Oxidative stress is considered to be the cause for onset
and the progression of type 2 diabetes mellitus (T2DM) and
complications including neuropathy. It is a deleterious process that
can be an important mediator of damage to cell structures: protein,
lipids and DNA. Data suggest that in patients with diabetes and
diabetic neuropathy DNA repair is impaired, which prevents effective
removal of lesions. Objective: The aim of our study was to evaluate
the association of the hOGG1 (326 Ser/Cys) and XRCC1 (194
Arg/Trp, 399 Arg/Gln) gene polymorphisms whose protein is
involved in the BER pathway with DNA repair efficiency in patients
with diabetes type 2 and diabetic neuropathy compared to the healthy
subjects. Genotypes were determined by PCR-RFLP analysis in 385
subjects, including 117 with type 2 diabetes, 56 with diabetic
neuropathy and 212 with normal glucose metabolism. The
polymorphisms studied include codon 326 of hOGG1 and 194, 399
of XRCC1 in the base excision repair (BER) genes. Comet assay was
carried out using peripheral blood lymphocytes from the patients and
controls. This test enabled the evaluation of DNA damage in cells
exposed to hydrogen peroxide alone and in the combination with the
endonuclease III (Nth). The results of the analysis of polymorphism
were statistically examination by calculating the odds ratio (OR) and
their 95% confidence intervals (95% CI) using the ¤ç2-tests. Our data
indicate that patients with diabetes mellitus type 2 (including those
with neuropathy) had higher frequencies of the XRCC1 399Arg/Gln
polymorphism in homozygote (GG) (OR: 1.85 [95% CI: 1.07-3.22],
P=0.3) and also increased frequency of 399Gln (G) allele (OR: 1.38
[95% CI: 1.03-1.83], P=0.3). No relation to other polymorphisms
with increased risk of diabetes or diabetic neuropathy. In T2DM
patients complicated by neuropathy, there was less efficient repair of
oxidative DNA damage induced by hydrogen peroxide in both the
presence and absence of the Nth enzyme. The results of our study
suggest that the XRCC1 399 Arg/Gln polymorphism is a significant
risk factor of T2DM in Polish population. Obtained data suggest a
decreased efficiency of DNA repair in cells from patients with
diabetes and neuropathy may be associated with oxidative stress.
Additionally, patients with neuropathy are characterized by even
greater sensitivity to oxidative damage than patients with diabetes,
which suggests participation of free radicals in the pathogenesis of
neuropathy.
Abstract: The objective from this paper is to design a solar
thermal engine for space vehicles orbital control and electricity
generation. A computational model is developed for the prediction of
the solar thermal engine performance for different design parameters and conditions in order to enhance the engine efficiency. The engine is divided into two main subsystems. First, the concentrator dish
which receives solar energy from the sun and reflects them to the
cavity receiver. The second one is the cavity receiver which receives
the heat flux reflected from the concentrator and transfers heat to the
fluid passing over. Other subsystems depend on the application required from the engine. For thrust application, a nozzle is
introduced to the system for the fluid to expand and produce thrust.
Hydrogen is preferred as a working fluid in the thruster application.
Results model developed is used to determine the thrust for a
concentrator dish 4 meters in diameter (provides 10 kW of energy),
focusing solar energy to a 10 cm aperture diameter cavity receiver.
The cavity receiver outer length is 50 cm and the internal cavity is 47
cm in length. The suggested design material of the internal cavity is
tungsten to withstand high temperature. The thermal model and
analysis shows that the hydrogen temperature at the plenum reaches
2000oK after about 250 seconds for hot start operation for a flow rate
of 0.1 g/sec.Using solar thermal engine as an electricity generation
device on earth is also discussed. In this case a compressor and
turbine are used to convert the heat gained by the working fluid (air)
into mechanical power. This mechanical power can be converted into
electrical power by using a generator.
Abstract: The aim of this study is to find out and analyze the
role of gender and age on the perceptions of students to the distant
online program offered by Vocational High School in Sakarya
University. The research is based on a questionnaire as a mean of
data collection method to find out the role of age and gender on the
student-s perceptions toward online education, and the study
progressed through finding relationships between the variables used
in the data collection instrument. The findings of the analysis
revealed that although the students registered to the online program
by will, they preferred the traditional face-to-face education due to
the difficulty of the nonverbal communication, their incompetence of
using the technology required, and their belief in traditional face-toface
learning more than online education.
Regarding gender, the results showed that the female students
have a better perception of the online education as opposed to the
male students. Regarding age, the results showed that the older the
students are the more is their preference towards attending face-toface
classes.
Abstract: In mechanical and environmental engineering, mixed
convection is a frequently encountered thermal fluid phenomenon
which exists in atmospheric environment, urban canopy flows, ocean
currents, gas turbines, heat exchangers, and computer chip cooling
systems etc... . This paper deals with a numerical investigation of
mixed convection in a vertical heated channel. This flow results from
the mixing of the up-going fluid along walls of the channel with the
one issued from a flat nozzle located in its entry section. The fluiddynamic
and heat-transfer characteristics of vented vertical channels
are investigated for constant heat-flux boundary conditions, a
Rayleigh number equal to 2.57 1010, for two jet Reynolds number
Re=3 103 and 2104 and the aspect ratio in the 8-20 range. The system
of governing equations is solved with a finite volumes method and an
implicit scheme. The obtained results show that the turbulence and
the jet-wall interaction activate the heat transfer, as does the drive of
ambient air by the jet. For low Reynolds number Re=3 103, the
increase of the aspect Ratio enhances the heat transfer of about 3%,
however; for Re=2 104, the heat transfer enhancement is of about
12%. The numerical velocity, pressure and temperature fields are
post-processed to compute the quantities of engineering interest such
as the induced mass flow rate, and average Nusselt number, in terms
of Rayleigh, Reynolds numbers and dimensionless geometric
parameters are presented.
Abstract: This study explored the relationship between
occupational stress and the perceived effectiveness of men and
women managers in Ghanaian organizations. The exploration is
underlined by attempt to understand the degree to which male and
female managers in Ghanaian organizations experience occupational
stress at the workplace. The purpose is to examine the sources and
extents of occupational stress experienced by male and female
managers in Ghana. Data was collected using questionnaires and
analyzed using both descriptive statistics and correlation analysis.
The results showed that female managers in Ghana are more likely to
report of more stress experiences in the workplace than their male
counterparts. The female managers are more likely to perceive role
conflict and alienation as job stressors while the male managers
perceived blocked career as a major source of workplace stress. It is
concluded that despite the female managers experiencing enormous
level of occupational stress, there was no significant differences
between their managerial effectiveness and that of the male.
Abstract: The steady-state temperature for one-dimensional transpiration cooling system has been conducted experimentally and numerically to investigate the heat transfer characteristics of combined convection and radiation. The Nickel –Chrome (Ni-Cr) open-cellular porous material having porosity of 0.93 and pores per inch (PPI) of 21.5 was examined. The upper surface of porous plate was heated by the heat flux of incoming radiation varying from 7.7 - 16.6 kW/m2 whereas air injection velocity fed into the lower surface was varied from 0.36 - 1.27 m/s, and was then rearranged as Reynolds number (Re). For the report of the results in the present study, two efficiencies including of temperature and conversion efficiency were presented. Temperature efficiency indicating how close the mean temperature of a porous heat plate to that of inlet air, and increased rapidly with the air injection velocity (Re). It was then saturated and had a constant value at Re higher than 10. The conversion efficiency, which was regarded as the ability of porous material in transferring energy by convection after absorbed from heat radiation, decreased with increasing of the heat flux and air injection velocity. In addition, it was then asymptotic to a constant value at the Re higher than 10. The numerical predictions also agreed with experimental data very well.
Abstract: With the beginning of the new century, man still faces
many challenges in how to form and develop his urban environment. To meet these challenges, many cities have tried to develop its visual
image. This is by transforming their urban environment into a branded visual image; this is at the level of squares, the main roads, the borders, and the landmarks.
In this realm, the paper aims at activating the role of branded urban spaces as an approach for the development of visual image of cities, especially in Egypt. It concludes the need to recognize the importance of developing the visual image in Egypt, through directing the urban planners to the important role of such spaces in achieving sustainability.
Abstract: Previous studies have shown that there are arguments
regarding the reliability and validity of the Ashworth and Modified
Ashworth Scale towards evaluating patients diagnosed with upper
limb disorders. These evaluations depended on the raters’ experiences.
This initiated us to develop an upper limb disorder part-task trainer
that is able to simulate consistent upper limb disorders, such as
spasticity and rigidity signs, based on the Modified Ashworth Scale to
improve the variability occurring between raters and intra-raters
themselves. By providing consistent signs, novice therapists would be
able to increase training frequency and exposure towards various
levels of signs. A total of 22 physiotherapists and occupational
therapists participated in the study. The majority of the therapists
agreed that with current therapy education, they still face problems
with inter-raters and intra-raters variability (strongly agree 54%; n =
12/22, agree 27%; n = 6/22) in evaluating patients’ conditions. The
therapists strongly agreed (72%; n = 16/22) that therapy trainees
needed to increase their frequency of training; therefore believe that
our initiative to develop an upper limb disorder training tool will help
in improving the clinical education field (strongly agree and agree
63%; n = 14/22).
Abstract: Nozzle is the main part of various spinning systems
such as air-jet and Murata air vortex systems. Recently, many
researchers worked on the usage of the nozzle on different spinning
systems such as conventional ring and compact spinning systems. In
these applications, primary purpose is to improve the yarn quality. In
present study, it was produced the yarns with two different nozzle
types and determined the changes in yarn properties. In order to
explain the effect of the nozzle, airflow structure in the nozzle was
modelled and airflow variables were determined. In numerical
simulation, ANSYS 12.1 package program and Fluid Flow (CFX)
analysis method was used. As distinct from the literature, Shear
Stress Turbulent (SST) model is preferred. And also air pressure at
the nozzle inlet was measured by electronic mass flow meter and
these values were used for the simulation of the airflow. At last, the
yarn was modelled and the area from where the yarn is passing was
included to the numerical analysis.
Abstract: The paper depicts air velocity values, reproduced by laser Doppler anemometer (LDA) and ultrasonic anemometer (UA), relations with calculated ones from flow rate measurements using the gas meter which calibration uncertainty is ± (0.15 – 0.30) %. Investigation had been performed in channel installed in aerodynamical facility used as a part of national standard of air velocity. Relations defined in a research let us confirm the LDA and UA for air velocity reproduction to be the most advantageous measures. The results affirm ultrasonic anemometer to be reliable and favourable instrument for measurement of mean velocity or control of velocity stability in the velocity range of 0.05 m/s – 10 (15) m/s when the LDA used. The main aim of this research is to investigate low velocity regularities, starting from 0.05 m/s, including region of turbulent, laminar and transitional air flows. Theoretical and experimental results and brief analysis of it are given in the paper. Maximum and mean velocity relations for transitional air flow having unique distribution are represented. Transitional flow having distinctive and different from laminar and turbulent flow characteristics experimentally have not yet been analysed.
Abstract: This article is devoted to the analysis of results of
sociological researches carried out by authors directed on studying of
opinion of representatives of small, medium and big business on
formation of the Customs Union, Common Free Market Zone with
participation of Kazakhstan, Russia and Belarus.
It-s forecasted that companies, their branches will interpenetrate
with registration and moving their businesses to regions with more
beneficial conditions. They say that in Kazakhstan there are more
profitable geo-strategic operating environment for business and lower
taxes. Russia using this opportunity will create new conditions for
expansion into other countries of Central Asia and China. Opinions
of participants of questionnaire and expert poll different in estimation
of value of these two integration mechanisms since market segments
on the one hand extend, but also on the other hand - loss of exclusive
influence in certain fields of activity.
Abstract: In this work a dynamic model of a new quadrotor aerial
vehicle that is equipped with a tilt-wing mechanism is presented.
The vehicle has the capabilities of vertical take-off/landing (VTOL)
like a helicopter and flying horizontal like an airplane. Dynamic
model of the vehicle is derived both for vertical and horizontal flight
modes using Newton-Euler formulation. An LQR controller for the
vertical flight mode has also been developed and its performance
has been tested with several simulations.
Abstract: The goals of the present research are to estimate Six Sigma implementation in Latvian commercial banks and to identify the perceived benefits of its implementation. To achieve the goals, the authors used sequential explanatory method. To obtain empirical data, the authors have developed the questionnaire and adapted it for the employees of Latvian commercial banks. The questions are related to Six Sigma implementation and its perceived benefits. The questionnaire mainly consists of closed questions, the evaluation of which is based on 5 point Likert scale. The obtained empirical data has shown that of the two hypotheses put forward in the present research – Hypothesis 1 – has to be rejected, while Hypothesis 2 has been partially confirmed. The authors have also faced some research limitations related to the fact that the participants in the questionnaire belong to different rank of the organization hierarchy.
Abstract: In this paper some procedures for building confidence intervals for the reliability in stress-strength models are discussed and empirically compared. The particular case of a bivariate normal setup is considered. The confidence intervals suggested are obtained employing approximations or asymptotic properties of maximum likelihood estimators. The coverage and the precision of these intervals are empirically checked through a simulation study. An application to real paired data is also provided.
Abstract: Hypersonic flows around spatial vehicles during their
reentry phase in planetary atmospheres are characterized by intense
aerothermal phenomena. The aim of this work is to analyze high
temperature flows around an axisymmetric blunt body taking into
account chemical and vibrational non-equilibrium for air mixture
species. For this purpose, a finite volume methodology is employed
to determine the supersonic flow parameters around the axisymmetric
blunt body, especially at the stagnation point and along the wall of
spacecraft for several altitudes. This allows the capture shock wave
before a blunt body placed in supersonic free stream. The numerical
technique uses the Flux Vector Splitting method of Van Leer. Here,
adequate time stepping parameter, along with CFL coefficient and
mesh size level are selected to ensure numerical convergence, sought
with an order of 10-8
Abstract: Evaluation of educational portals is an important
subject area that needs more attention from researchers. A university
that has an educational portal which is difficult to use and interact by
teachers or students or management staff can reduce the position and
reputation of the university. Therefore, it is important to have the
ability to make an evaluation of the quality of e-services the
university provide to improve them over time.
The present study evaluates the usability of the Information
Technology Faculty portal at University of Benghazi. Two evaluation
methods were used: a questionnaire-based method and an online
automated tool-based method. The first method was used to measure
the portal's external attributes of usability (Information, Content and
Organization of the portal, Navigation, Links and Accessibility,
Aesthetic and Visual Appeal, Performance and Effectiveness and
educational purpose) from users' perspectives, while the second
method was used to measure the portal's internal attributes of
usability (number and size of HTML files, number and size of images,
load time, HTML check errors, browsers compatibility problems,
number of bad and broken links), which cannot be perceived by the
users. The study showed that some of the usability aspects have been
found at the acceptable level of performance and quality, and some
others have been found otherwise. In general, it was concluded that
the usability of IT faculty educational portal generally acceptable.
Recommendations and suggestions to improve the weakness and
quality of the portal usability are presented in this study.
Abstract: The purpose of this research was to demonstrate
prevalence of post-exposure preventive measures (PEP) after needlestick
injuries and its relationship with locus of control beliefs in a
sample of medical students. In this cross-sectional study, 300 medical
students with history of having experienced needle stick injuries
(NSI) for at least once filled in a questionnaire to determine if they
perceived themselves to be responsible and effective in preventing
blood born infections after NSI. About 38% of students did not seek
any professional consult or PEP after NSI due to lack of enough time
or access, anxiety about tests results, belief in uselessness of followup
and not being able to change destiny. These 114 students were not
different from others regarding their scores on NSI specific scale of
locus of health control. Thus, the potentiality of NSI locus of control
beliefs in predicting PEP was not seen in this study.
Abstract: Endovascular aneurysm repair is a new and minimally invasive repair for patients with abdominal aortic aneurysm (AAA). This method has potential advantages that are incomparable with other repair methods. However, the enlargement of aneurysm in the absence of endoleak, which is known as endotension, may occur as one of post-operative compliances of this method. Typically, endotension is mainly as a result of pressure transmitted to aneurysm sac by endovascular installed graft. After installation of graft the aneurysm sac reduces significantly but remains non-zero. There are some factors which affect this pressure transmitted. In this study, the geometry features of installed vascular graft have been considered. It is inferred that graft neck angle and iliac bifurcation angle are two factors which can affect the drag force on graft and consequently the pressure transmitted to aneurysm.
Abstract: Bean common mosaic necrosis virus (BCMNV) is a
potyvirus with a worldwide distribution. This virus causes serious
economic losses in Iran in many leguminoses. During 20008,
samples were collected from soybeans fields in Tehran Province.
Four isolates (S1, S2 and S3) were inoculated on 15 species of
Cucurbitaceae, Chenopodiaceae, Solanacae and Leguminosae.
Chenopodium quinoa and C. amaranticolor.
Did not developed any symptoms.all isolates caused mosaic
symptoms on Phaseolus vulgaris cv. Red Kidney and P. vulgaris cv.
Bountiful. The molecular weights of coat protein using SDS-PAGE
and western blotting were estimated at 33 kDa. Reverse transcription
polymerase chain reaction (RT-PCR) was performed using one
primer pairs designed by L. XU et al. An approximately 920 bp
fragment was amplified with a specific primer.
Abstract: Ten lactating multiparous Holstein cows were used in
a cross-over design with two dietary treatments and 28-d periods
(with 14 d as an adaptation) to study the effect of restaurant fat on
milk production and composition. Each cow was offered 14.7 kg
DM /d of the basal concentrate diet based on barley and corn (crude
protein = 17.7%, neutral detergent fiber = 23.5%, and acid detergent
fiber = 5.8% of dry matter) with free access to alfalfa. Dietary
treatments were arranged as supplying each cow with 0 (CONTROL)
or 150 g/day (RF) of restaurant fat. Supplemental RF did not
significantly (P > 0.25) affect milk yield, composition, and
composition yields, except for milk fat contents. Milk fat contents
were depressed (P < 0.05) with supplemental RF. Our results indicate
that RF could depress milk fat without affecting milk yield and that
the depression in milk fat in response to RF precedes the depression
in milk yield.