Abstract: Deteriorating quality of the pedestrian environment
and the increasing risk of pedestrian crashes are major concerns for
most of the cities in India. The recent shift in the priority to
motorized transport and the abating condition of existing pedestrian
facilities can be considered as prime reasons for the increasing
pedestrian related crashes in India. Bengaluru City – the IT capital
hub of the nation is not much different from this. The increase in
number of pedestrian crashes in Bengaluru reflects the same. To
resolve this issue and to ensure safe, sustainable and pedestrian
friendly sidewalks, Govt. of Karnataka, India has implemented
newfangled pedestrian sidewalks popularized programme named
Tender S.U.R.E. (Specifications for Urban Road Execution) projects.
Tender SURE adopts unique urban street design guidelines where the
pedestrians are given prime preference. The present study presents an
assessment of the quality and performance of the pedestrian side walk
and the walkability index of the newly built pedestrian friendly
sidewalks. Various physical and environmental factors affecting
pedestrian safety are identified and studied in detail. The pedestrian
mobility is quantified through Pedestrian Level of Service (PLoS)
and the pedestrian walking comfort is measured by calculating the
Walkability Index (WI). It is observed that the new initiatives taken
in reference to improving pedestrian safety have succeeded in
Bengaluru by attaining a level of Service of ‘A’ and with a good WI
score.
Abstract: Background: Islands in the Mediterranean region offer
opportunities for various industries to take advantage of the
facilitation and use of versatile floating structures in coastal areas. In
the context of dense land use, marine structures can contribute to
ensure both terrestrial and marine resource sustainability. Objective:
The aim of this paper is to present and critically discuss an array of
issues that characterize the design process of a floating structure for
coastal areas and to present the challenges and opportunities of
providing such multifunctional and versatile structures around the
Maltese coastline. Research Design: A three-tier research design
commenced with a systematic literature review. Semi-structured
interviews with stakeholders including a naval architect, a marine
engineer and civil designers were conducted. A second stage
preceded a focus group with stakeholders in design and construction
of marine lightweight structures. The three tier research design
ensured triangulation of issues. All phases of the study were
governed by research ethics. Findings: Findings were grouped into
three main themes: excellence, impact and implementation. These
included design considerations, applications and potential impacts on
local industry. Literature for the design and construction of marine
structures in the Maltese Islands presented multiple gaps in the
application of marine structures for local industries. Weather
conditions, depth of sea bed and wave actions presented limitations
on the design capabilities of the structure. Conclusion: Water
structures offer great potential and conclusions demonstrate the
applicability of such designs for Maltese waters. There is still no such
provision within Maltese coastal areas for multi-purpose use. The
introduction of such facilities presents a range of benefits for visiting
tourists and locals thereby offering wide range of services to tourism
and marine industry. Costs for construction and adverse weather
conditions were amongst the main limitations that shaped design
capacities of the water structures.
Abstract: In terms of ITS, information on link characteristic is an essential factor for plan or operation. But in practical cases, not every link has installed sensors on it. The link that does not have data on it is called “Missing Link”. The purpose of this study is to impute data of these missing links. To get these data, this study applies the machine learning method. With the machine learning process, especially for the deep learning process, missing link data can be estimated from present link data. For deep learning process, this study uses “Recurrent Neural Network” to take time-series data of road. As input data, Dedicated Short-range Communications (DSRC) data of Dalgubul-daero of Daegu Metropolitan Area had been fed into the learning process. Neural Network structure has 17 links with present data as input, 2 hidden layers, for 1 missing link data. As a result, forecasted data of target link show about 94% of accuracy compared with actual data.
Abstract: The Extended Enterprise Resource Planning (ERPII)
system usually requires massive amounts of storage space, powerful
servers, and large upfront and ongoing investments to purchase and
manage the software and the related hardware which are not
affordable for organizations. In recent decades, organizations prefer
to adapt their business structures with new technologies for
remaining competitive in the world economy. Therefore, cloud
computing (which is one of the tools of information technology (IT))
is a modern system that reveals the next-generation application
architecture. Also, cloud computing has had some advantages that
reduce costs in many ways such as: lower upfront costs for all
computing infrastructure and lower cost of maintaining and
supporting. On the other hand, traditional ERPII is not responding for
huge amounts of data and relations between the organizations. In this
study, based on a literature study, ERPII is investigated in the context
of cloud computing where the organizations operate more efficiently.
Also, ERPII conditions have a response to needs of organizations in
large amounts of data and relations between the organizations.
Abstract: The psychological present has an actual extension.
When a sequence of instantaneous stimuli falls in this short interval
of time, observers perceive a compresence of events in succession
and the temporal order depends on the qualitative relationships
between the perceptual properties of the events. Two experiments
were carried out to study the influence of perceptual grouping, with
and without temporal displacement, on the duration of auditory
sequences. The psychophysical method of adjustment was adopted.
The first experiment investigated the effect of temporal displacement
of a white noise on sequence duration. The second experiment
investigated the effect of temporal displacement, along the pitch
dimension, on temporal shortening of sequence. The results suggest
that the temporal order of sounds, in the case of temporal
displacement, is organized along the pitch dimension.
Abstract: Safety and security concerns play a key role during
the design of civil UAs (aircraft controlled by a pilot who is not onboard
it) by the producers and the offer of different services by the
operators. At present, European countries have fragmented
regulations about the manufacture and use of civil drones, therefore
the European institutions are trying to approach all these regulations
into a common one. In this sense, not only law but also ethics can
give guidelines to the industry in order to obtain better reports from
their clients. With our results, we would like to give advice to the
European industry, as well as give new insights to the academia and
policymakers.
Abstract: Butterfly valves are widely used industrial piping components as on-off and flow controlling devices. The main challenge in the design process of this type of valves is the correct dimensioning to ensure proper mechanical performance as well as to minimise flow losses that affect the efficiency of the system. Butterfly valves are typically dimensioned in a closed position based on mechanical approaches considering uniform hydrostatic pressure, whereas the flow losses are analysed by means of CFD simulations. The main limitation of these approaches is that they do not consider either the influence of the dynamics of the manoeuvring stage or coupled phenomena. Recent works have included the influence of the flow on the mechanical behaviour for different opening angles by means of one-way FSI approach. However, these works consider steady-state flow for the selected angles, not capturing the effect of the transient flow evolution during the manoeuvring stage. Two-way FSI modelling approach could allow overcoming such limitations providing more accurate results. Nevertheless, the use of this technique is limited due to the increase in the computational cost. In the present work, the applicability of FSI one-way and two-way approaches is evaluated for the analysis of butterfly valves, showing that not considering fluid-structure coupling involves not capturing the most critical situation for the valve disc.
Abstract: Minimizing the weight in flexible structures means
reducing material and costs as well. However, these structures could
become prone to vibrations. Attenuating these vibrations has become
a pivotal engineering problem that shifted the focus of many research
endeavors. One technique to do that is to design and implement
an active control system. This system is mainly composed of a
vibrating structure, a sensor to perceive the vibrations, an actuator
to counteract the influence of disturbances, and finally a controller to
generate the appropriate control signals. In this work, two different
techniques are explored to create two different mathematical models
of an active control system. The first model is a finite element model
with a reduced number of nodes and it is called a super-element.
The second model is in the form of state-space representation, i.e.
a set of partial differential equations. The damping coefficients are
calculated and incorporated into both models. The effectiveness of
these models is demonstrated when the system is excited by its first
natural frequency and an active control strategy is developed and
implemented to attenuate the resulting vibrations. Results from both
modeling techniques are presented and compared.
Abstract: An increasing degree of automation in air traffic will also change the role of the air traffic controller (ATCO). ATCOs will fulfill significantly more monitoring tasks compared to today. However, this rather passive role may lead to Out-Of-The-Loop (OOTL) effects comprising vigilance decrement and less situation awareness. The project MINIMA (Mitigating Negative Impacts of Monitoring high levels of Automation) has conceived a system to control and mitigate such OOTL phenomena. In order to demonstrate the MINIMA concept, an experimental simulation set-up has been designed. This set-up consists of two parts: 1) a Task Environment (TE) comprising a Terminal Maneuvering Area (TMA) simulator as well as 2) a Vigilance and Attention Controller (VAC) based on neurophysiological data recording such as electroencephalography (EEG) and eye-tracking devices. The current vigilance level and the attention focus of the controller are measured during the ATCO’s active work in front of the human machine interface (HMI). The derived vigilance level and attention trigger adaptive automation functionalities in the TE to avoid OOTL effects. This paper describes the full-scale experimental set-up and the component development work towards it. Hence, it encompasses a pre-test whose results influenced the development of the VAC as well as the functionalities of the final TE and the two VAC’s sub-components.
Abstract: E-commerce is a business model that allows companies to optimize the processes of buying, selling, transferring goods and exchanging services through computer networks or the Internet. In Peru, the electronic commerce is used infrequently. This situation is due, in part to the fact that there is no model that allows companies to implement an e-commerce solution, which means that most SMEs do not have adequate knowledge to adapt to electronic commerce. In this work, a reference model is proposed for the implementation of an e-commerce solution in Peruvian SMEs in the retail sector. It consists of five phases: Business Analysis, Business Modeling, Implementation, Post Implementation and Results. The present model was validated in a SME of the Peruvian retail sector through the implementation of an electronic commerce platform, through which the company increased its sales through the delivery channel by 10% in the first month of deployment. This result showed that the model is easy to implement, is economical and agile. In addition, it allowed the company to increase its business offer, adapt to e-commerce and improve customer loyalty.
Abstract: The rapid progress of technology in today's competitive conditions has also accelerated companies' technology development activities. As a result, companies are paying more attention to R&D studies and are beginning to allocate a larger share to R&D projects. A more systematic, comprehensive, target-oriented implementation of R&D studies is crucial for the company to achieve successful results. As a consequence, Technology Roadmap (TRM) is gaining importance as a management tool. It has critical prospects for achieving medium and long term success as it contains decisions about past business, future plans, technological infrastructure. When studies on TRM are examined, projects to be placed on the roadmap are selected by many different methods. Generally preferred methods are based on multi-criteria decision making methods. Management of selected projects becomes an important point after the selection phase of the projects. At this stage, TRM are used. TRM can be created in many different ways so that each institution can prepare its own Technology Roadmap according to their strategic plan. Depending on the intended use, there can be TRM with different layers at different sizes. In the evaluation phase of the R&D projects and in the creation of the TRM, HAVELSAN, Turkey's largest defense company in the software field, carries out this process with great care and diligence. At the beginning, suggested R&D projects are evaluated by the Technology Management Board (TMB) of HAVELSAN in accordance with the company's resources, objectives, and targets. These projects are presented to the TMB periodically for evaluation within the framework of certain criteria by board members. After the necessary steps have been passed, the approved projects are added to the time-based TRM, which is composed of four layers as market, product, project and technology. The use of a four-layered roadmap provides a clearer understanding and visualization of company strategy and objectives. This study demonstrates the benefits of using TRM, four-layered Technology Roadmapping and the possibilities for the institutions in the defense industry.
Abstract: The problems of technological development for the Russian Federation take on special significance in the context of modernization of the production base. The complexity of the position of the Russian economy is that it cannot be attributed fully to developing ones. Russia is a strong industrial power that has gone through the processes of destructive de-industrialization in the conditions of changing its economic and political structure. The need to find ways for re-industrialization is not a unique task for the economies of industrially developed countries. Under the influence of production outsourcing for 20 years, the industrial potential of leading economies of the world was regressed against the backdrop of the ascent of China, a new industrial giant. Therefore, methods, tools, and techniques utilized for industrial renaissance in EU may be used to achieve a technological leap in the Russian Federation, especially since the temporary gap of 5-7 years makes it possible to analyze best practices and use those technological transfer tools that have shown the greatest efficiency. In this article, methods of technological transfer are analyzed, the role of technological audit is justified, and factors are analyzed that influence the successful process of commercialization of technologies.
Abstract: 5-FU is a chemotherapeutic agent that has been used in colorectal cancer (CRC) treatment. However, it is usually associated with the acquired resistance, which decreases the therapeutic effects of 5-FU. miR-200c is involved in chemotherapeutic drug resistance, but its mechanism is not fully understood. In this study, the effect of inhibition of miR-200c in sensitivity of HCT-116 CRC cells to 5-FU was evaluated. HCT-116 cells were transfected with LNA-anti- miR-200c for 48 h. mRNA expression of miR-200c was evaluated using quantitative real- time PCR. The protein expression of phosphatase and tensin homolog (PTEN) and E-cadherin were analyzed by western blotting. Annexin V and propidium iodide staining assay were applied for apoptosis detection. The caspase-3 activation was evaluated by an enzymatic assay. The results showed LNA-anti-miR-200c inhibited the expression of PTEN and E-cadherin protein, apoptosis and activation of caspase 3 compared with control cells. In conclusion, these results suggest that miR-200c as a prognostic marker can overcome to 5-FU chemoresistance in CRC.
Abstract: Traffic congestion is a worldwide issue, especially in developing countries. This is also the case of Afghanistan, especially in Kabul-the capital city, whose rapid population growth makes it the fifth fastest growing city in the world. Traffic congestion affects not only the mobility of people and goods but also the air quality that leads to numerous deaths (3000 people) every year. There are many factors that contribute to traffic congestion. The insufficiency and inefficiency of public transportation system along with the increase of private vehicles can be considered among the most important contributing factors. This paper addresses the traffic congestion and attempts to suggest possible solutions that can help improve the current public transportation system in Kabul. To this end, the methodology used in this paper includes field work conducted in Kabul city and literature review. The outcome suggests that improving the public transportation system is likely to contribute to the reduction of traffic congestion and the improvement of air quality, thereby reducing the number of death related to air quality.
Abstract: The majority of the building stock of Budapest inner districts was built around the turn of the 19th and 20th century. Although the structural stability of the buildings is not questioned, as the load bearing structures are in sufficient state, the secondary structures are aged, resulting unsatisfactory energetic state. The renovation of these historical buildings requires special methodology and technology: their ornamented facades and custom-made fenestration cannot be insulated or exchanged with conventional solutions without damaging the heritage values. The present paper aims to introduce and systematize the possible technological solutions for heritage respecting energy retrofit in case of a historical residential building stock. Through case study, the possible energy saving potential is also calculated using multiple renovation scenarios.
Abstract: We report the enhancement of Raman scattering
signal by one order of magnitude using photonic nanojet (PNJ) of a
lollipop shaped dielectric microstructure (LSDM) fabricated by a
pulsed CO₂ laser. Here, the PNJ is generated by illuminating sphere
portion of the LSDM with non-resonant laser. Unlike the surface
enhanced Raman scattering (SERS) technique, this technique is
simple, and the obtained results are highly reproducible. In addition,
an efficient technique is proposed to enhance the SERS signal with
the help of high quality factor optical resonance (whispering gallery
mode) of a LSDM. From the theoretical simulations, it has been
found that at least an order of magnitude enhancement in the SERS
signal could be achieved easily using the proposed technique. We
strongly believe that this report will enable the research community
for improving the Raman scattering signals.
Abstract: This paper studies a case where the targeted surface roughness of fused deposition modeling (FDM) additive manufacturing process is improved. The process is designing to reduce or eliminate the defects and improve the process capability index Cp and Cpk for an FDM additive manufacturing process. The baseline Cp is 0.274 and Cpk is 0.654. This research utilizes the Taguchi methodology, to eliminate defects and improve the process. The Taguchi method is used to optimize the additive manufacturing process and printing parameters that affect the targeted surface roughness of FDM additive manufacturing. The Taguchi L9 orthogonal array is used to organize the parameters' (four controllable parameters and one non-controllable parameter) effectiveness on the FDM additive manufacturing process. The four controllable parameters are nozzle temperature [°C], layer thickness [mm], nozzle speed [mm/s], and extruder speed [%]. The non-controllable parameter is the environmental temperature [°C]. After the optimization of the parameters, a confirmation print was printed to prove that the results can reduce the amount of defects and improve the process capability index Cp from 0.274 to 1.605 and the Cpk from 0.654 to 1.233 for the FDM additive manufacturing process. The final results confirmed that the Taguchi methodology is sufficient to improve the surface roughness of FDM additive manufacturing process.
Abstract: The objective of this research is to optimize the process of cutting cylindrical workpieces utilizing live tooling on a HAAS ST-20 lathe. Surface roughness (Ra) has been investigated as the indicator of quality characteristics for machining process. Aluminum alloy was used to conduct experiments due to its wide range usages in engineering structures and components where light weight or corrosion resistance is required. In this study, Taguchi methodology is utilized to determine the effects that each of the parameters has on surface roughness (Ra). A total of 18 experiments of each process were designed according to Taguchi’s L9 orthogonal array (OA) with four control factors at three levels of each and signal-to-noise ratios (S/N) were computed with Smaller the better equation for minimizing the system. The optimal parameters identified for the surface roughness of the turning operation utilizing live tooling were a feed rate of 3 inches/min(A3); a spindle speed of 1300 rpm(B3); a 2-flute titanium nitrite coated 3/8” endmill (C1); and a depth of cut of 0.025 inches (D2). The mean surface roughness of the confirmation runs in turning operation was 8.22 micro inches. The final results demonstrate that Taguchi methodology is a sufficient way of process improvement in turning process on surface roughness.
Abstract: Low-temperature waste heat is abundant in the process industries, and large amounts of Liquefied Natural Gas (LNG) cold energy are discarded without being recovered properly in LNG terminals. Power generation is an effective way to utilize low-temperature waste heat and LNG cold energy simultaneously. Organic Rankine Cycles (ORCs) and CO2 power cycles are promising technologies to convert low-temperature waste heat and LNG cold energy into electricity. If waste heat and LNG cold energy are utilized simultaneously in one system, the performance may outperform separate systems utilizing low-temperature waste heat and LNG cold energy, respectively. Low-temperature waste heat acts as the heat source and LNG regasification acts as the heat sink in the combined system. Due to the large temperature difference between the heat source and the heat sink, cascaded power cycle configurations are proposed in this paper. Cascaded power cycles can improve the energy efficiency of the system considerably. The cycle operating at a higher temperature to recover waste heat is called top cycle and the cycle operating at a lower temperature to utilize LNG cold energy is called bottom cycle in this study. The top cycle condensation heat is used as the heat source in the bottom cycle. The top cycle can be an ORC, transcritical CO2 (tCO2) cycle or supercritical CO2 (sCO2) cycle, while the bottom cycle only can be an ORC due to the low-temperature range of the bottom cycle. However, the thermodynamic path of the tCO2 cycle and sCO2 cycle are different from that of an ORC. The tCO2 cycle and the sCO2 cycle perform better than an ORC for sensible waste heat recovery due to a better temperature match with the waste heat source. Different combinations of the tCO2 cycle, sCO2 cycle and ORC are compared to screen the best configurations of the cascaded power cycles. The influence of the working fluid and the operating conditions are also investigated in this study. Each configuration is modeled and optimized in Aspen HYSYS. The results show that cascaded tCO2/ORC performs better compared with cascaded ORC/ORC and cascaded sCO2/ORC for the case study.
Abstract: The comparisons of mycobacterial genomes have identified several Mycobacterium tuberculosis-specific genomic regions that are absent in other mycobacteria and are known as regions of differences. Due to M. tuberculosis-specificity, the peptides encoded by these regions could be useful in the specific diagnosis of tuberculosis. To explore this possibility, overlapping synthetic peptides corresponding to 39 proteins predicted to be encoded by genes present in regions of differences were tested for antibody-reactivity with sera from tuberculosis patients and healthy subjects. The results identified four immunodominant peptides corresponding to four different proteins, with three of the peptides showing significantly stronger antibody reactivity and rate of positivity with sera from tuberculosis patients than healthy subjects. The fourth peptide was recognized equally well by the sera of tuberculosis patients as well as healthy subjects. Predication of antibody epitopes by bioinformatics analyses using ABCpred server predicted multiple linear epitopes in each peptide. Furthermore, peptide sequence analysis for sequence identity using BLAST suggested M. tuberculosis-specificity for the three peptides that had preferential reactivity with sera from tuberculosis patients, but the peptide with equal reactivity with sera of TB patients and healthy subjects showed significant identity with sequences present in nob-tuberculous mycobacteria. The three identified M. tuberculosis-specific immunodominant peptides may be useful in the serological diagnosis of tuberculosis.