Abstract: The agriculture lignocellulosic by-products are receiving increased attention, namely in the search for filter materials that retain contaminants from water. These by-products, specifically almond and hazelnut shells are abundant in Portugal once almond and hazelnuts production is a local important activity. Hazelnut and almond shells have as main constituents lignin, cellulose and hemicelluloses, water soluble extractives and tannins. Along the adsorption of heavy metals from contaminated waters, water soluble compounds can leach from shells and have a negative impact in the environment. Usually, the chemical characterization of treated water by itself may not show environmental impact caused by the discharges when parameters obey to legal quality standards for water. Only biological systems can detect the toxic effects of the water constituents. Therefore, the evaluation of toxicity by biological tests is very important when deciding the suitability for safe water discharge or for irrigation applications.
The main purpose of the present work was to assess the potential impacts of waters after been treated for heavy metal removal by hazelnut and almond shells adsorption systems, with short term acute toxicity tests.
To conduct the study, water at pH 6 with 25 mg.L-1 of lead, was treated with 10 g of shell per litre of wastewater, for 24 hours. This procedure was followed for each bark. Afterwards the water was collected for toxicological assays; namely bacterial resistance, seed germination, Lemna minor L. test and plant grow. The effect in isolated bacteria strains was determined by disc diffusion method and the germination index of seed was evaluated using lettuce, with temperature and humidity germination control for 7 days. For aquatic higher organism, Lemnas were used with 4 days contact time with shell solutions, in controlled light and temperature. For terrestrial higher plants, biomass production was evaluated after 14 days of tomato germination had occurred in soil, with controlled humidity, light and temperature.
Toxicity tests of water treated with shells revealed in some extent effects in the tested organisms, with the test assays showing a close behaviour as the control, leading to the conclusion that its further utilization may not be considered to create a serious risk to the environment.
Abstract: The study of proteomics reached unexpected levels of
interest, as a direct consequence of its discovered influence over some
complex biological phenomena, such as problematic diseases like
cancer. This paper presents the latest authors- achievements regarding
the analysis of the networks of proteins (interactome networks), by
computing more efficiently the betweenness centrality measure. The
paper introduces the concept of betweenness centrality, and then
describes how betweenness computation can help the interactome net-
work analysis. Current sequential implementations for the between-
ness computation do not perform satisfactory in terms of execution
times. The paper-s main contribution is centered towards introducing
a speedup technique for the betweenness computation, based on
modified shortest path algorithms for sparse graphs. Three optimized
generic algorithms for betweenness computation are described and
implemented, and their performance tested against real biological
data, which is part of the IntAct dataset.
Abstract: This paper presents the design, fabrication and
evaluation of magneto-rheological damper. Semi-active control
devices have received significant attention in recent years because
they offer the adaptability of active control devices without requiring
the associated large power sources. Magneto-Rheological (MR)
dampers are semi- active control devices that use MR fluids to
produce controllable dampers. They potentially offer highly reliable
operation and can be viewed as fail-safe in that they become passive
dampers if the control hardware malfunction. The advantage of MR
dampers over conventional dampers are that they are simple in
construction, compromise between high frequency isolation and
natural frequency isolation, they offer semi-active control, use very
little power, have very quick response, has few moving parts, have a
relax tolerances and direct interfacing with electronics. Magneto-
Rheological (MR) fluids are Controllable fluids belonging to the
class of active materials that have the unique ability to change
dynamic yield stress when acted upon by an electric or magnetic
field, while maintaining viscosity relatively constant. This property
can be utilized in MR damper where the damping force is changed by
changing the rheological properties of the fluid magnetically. MR
fluids have a dynamic yield stress over Electro-Rheological fluids
(ER) and a broader operational temperature range. The objective of
this papert was to study the application of an MR damper to vibration
control, design the vibration damper using MR fluids, test and
evaluate its performance. In this paper the Rheology and the theory
behind MR fluids and their use on vibration control were studied.
Then a MR vibration damper suitable for vehicle suspension was
designed and fabricated using the MR fluid. The MR damper was
tested using a dynamic test rig and the results were obtained in the
form of force vs velocity and the force vs displacement plots. The
results were encouraging and greatly inspire further research on the
topic.
Abstract: Optimization of cutting parameters important in precision machining in regards to efficiency and surface integrity of the machined part. Usually productivity and precision in machining is limited by the forces emanating from the cutting process. Due to the inherent varying nature of the workpiece in terms of geometry and material composition, the peak cutting forces vary from point to point during machining process. In order to increase productivity without compromising on machining accuracy, it is important to control these cutting forces. In this paper a fuzzy logic control algorithm is developed that can be applied in the control of peak cutting forces in milling of spherical surfaces using ball end mills. The controller can adaptively vary the feedrate to maintain allowable cutting force on the tool. This control algorithm is implemented in a computer numerical control (CNC) machine. It has been demonstrated that the controller can provide stable machining and improve the performance of the CNC milling process by varying feedrate.
Abstract: Pressures for urban redevelopment are intensifying in
all large cities. A new logic for urban development is required –
green urbanism – that provides a spatial framework for directing
population and investment inwards to brownfields and greyfields
precincts, rather than outwards to the greenfields. This represents
both a major opportunity and a major challenge for city planners in
pluralist liberal democracies. However, plans for more compact
forms of urban redevelopment are stalling in the face of community
resistance. A new paradigm and spatial planning platform is required
that will support timely multi-level and multi-actor stakeholder
engagement, resulting in the emergence of consensus plans for
precinct-level urban regeneration capable of more rapid
implementation. Using Melbourne, Australia as a case study, this
paper addresses two of the urban intervention challenges – where and
how – via the application of a 21st century planning tool ENVISION
created for this purpose.
Abstract: MRAM technology provides a combination of fast
access time, non-volatility, data retention and endurance. While a
growing interest is given to two-terminal Magnetic Tunnel Junctions
(MTJ) based on Spin-Transfer Torque (STT) switching as the
potential candidate for a universal memory, its reliability is
dramatically decreased because of the common writing/reading path.
Three-terminal MTJ based on Spin-Orbit Torque (SOT) approach
revitalizes the hope of an ideal MRAM. It can overcome the
reliability barrier encountered in current two-terminal MTJs by
separating the reading and the writing path. In this paper, we study
two possible writing schemes for the SOT-MTJ device based on
recently fabricated samples. While the first is based on precessional
switching, the second requires the presence of permanent magnetic
field. Based on an accurate Verilog-A model, we simulate the two
writing techniques and we highlight advantages and drawbacks of
each one. Using the second technique, pioneering logic circuits based
on the three-terminal architecture of the SOT-MTJ described in this
work are under development with preliminary attractive results.
Abstract: Effect of oral administration of “Gadagi" tea on liver
function was assessed on 50 healthy male albino rats which were
grouped and administered with different doses(mg/kg) i.e low dose
(380mg/kg, 415mg/kg, 365mg/kg, 315mg/kg for “sak", “sada" and
“magani" respectively), standard dose ( 760mg/kg, 830mg/kg,
730mg/kg for “sak-, “sada" and “magani" respectively) and high dose
(1500mg/kg, 1700mg/kg and 1460mg/kg for “sak--,"sada" and
“magani" groups respectively) for a period of four weeks. Animals
that were not administered with the tea constituted the control group.
At the end of fourth week, the animals were sacrificed and their
serum alanine aminotransferase (ALT), aspartate aminotransferase
(AST), alkaline phosphatase (ALP), total protein (TP), albumin
(ALB), and globulins (GLO) were determined. Mean serum ALT and
ALP activities were significantly higher (P
Abstract: This paper presents a part of research on the
rheological properties of bitumen modified by thermoplastic namely
linear low density polyethylene (LLDPE), high density polyethylene
(HDPE) and polypropylene (PP) and its interaction with 80 pen base
bitumen. As it is known that the modification of bitumen by the use
of polymers enhances its performance characteristics but at the same
time significantly alters its rheological properties. The rheological
study of polymer modified bitumen (PMB) was made through
penetration, ring & ball softening point and viscosity test. The results
were then related to the changes in the rheological properties of
polymer modified bitumen. It was observed that thermoplastic
copolymer shows profound effect on penetration rather than
softening point. The viscoelastic behavior of polymer modified
bitumen depend on the concentration of polymer, mixing
temperature, mixing technique, solvating power of base bitumen and
molecular structure of polymer used. PP offer better blend in
comparison to HDPE and LLDPE. The viscosity of base bitumen was
also enhanced with the addition of polymer. The pseudoplastic
behavior was more prominent for HDPE and LLDPE than PP. Best
results were obtained when polymer concentration was kept below
3%
Abstract: During recent years, the traditional learning
approaches have undergone fundamental changes due to the
emergence of new technologies such as multimedia, hypermedia and
telecommunication. E-learning is a modern world phenomenon that
has come into existence in the information age and in a knowledgebased
society. E-learning has developed significantly within a short
period of time. Thus it is of a great significant to secure information,
allow a confident access and prevent unauthorized accesses. Making
use of individuals- physiologic or behavioral (biometric) properties is
a confident method to make the information secure. Among the
biometrics, fingerprint is more acceptable and most countries use it as
an efficient methods of identification. This article provides a new
method to compare the fingerprint comparison by pattern recognition
and image processing techniques. To verify fingerprint, the shortest
distance method is used together with perceptronic multilayer neural
network functioning based on minutiae. This method is highly
accurate in the extraction of minutiae and it accelerates comparisons
due to elimination of false minutiae and is more reliable compared
with methods that merely use directional images.
Abstract: The use of new technologies such internet (e-mail, chat
rooms) and cell phones has steeply increased in recent years.
Especially among children and young people, use of technological
tools and equipments is widespread. Although many teachers and
administrators now recognize the problem of school bullying, few are
aware that students are being harassed through electronic
communication. Referred to as electronic bullying, cyber bullying, or
online social cruelty, this phenomenon includes bullying through email,
instant messaging, in a chat room, on a website, or through
digital messages or images sent to a cell phone. Cyber bullying is
defined as causing deliberate/intentional harm to others using internet
or other digital technologies. It has a quantitative research design nd
uses relational survey as its method. The participants consisted of
300 secondary school students in the city of Konya, Turkey. 195
(64.8%) participants were female and 105 (35.2%) were male. 39
(13%) students were at grade 1, 187 (62.1%) were at grade 2 and 74
(24.6%) were at grade 3. The “Cyber Bullying Question List"
developed by Ar─▒cak (2009) was given to students. Following
questions about demographics, a functional definition of cyber
bullying was provided. In order to specify students- human values,
“Human Values Scale (HVS)" developed by Dilmaç (2007) for
secondary school students was administered. The scale consists of 42
items in six dimensions. Data analysis was conducted by the primary
investigator of the study using SPSS 14.00 statistical analysis
software. Descriptive statistics were calculated for the analysis of
students- cyber bullying behaviour and simple regression analysis was
conducted in order to test whether each value in the scale could
explain cyber bullying behaviour.
Abstract: This study shows palynomorphological description of
pollen grains of Lamium garganicum, species of the family Labiatae.
Fresh material of this plant is taken in Mount Llogara, in Albania. By
comparison made between palinomorphological characteristics of
pollen grains of Lamium garganicum with those of Lamium
maculatum and Lamium purpureum, showed that granules have
similarities in the number of furrows. The pollen grains of Lamium
garganicum were larger in length and width than those of Lamium
maculatum and almost equal with those of Lamium purpureum.
Furrows are longer than those of pollen grains in Lamium maculatum
and shorter than those of Lamium purpureum. The layer of exine of
Lamium garganicum was thinner than that of two others. The
sculpture of exine was fine reticulate, where reticulas were uniform
whereas in Lamium purpureum was verrucate, with small verrucae; in
Lamium maculatum was reticulate.
Abstract: Yeast cells live in a constantly changing environment that requires the continuous adaptation of their genomic program in order to sustain their homeostasis, survive and proliferate. Due to the advancement of high throughput technologies, there is currently a large amount of data such as gene expression, gene deletion and protein-protein interactions for S. Cerevisiae under various environmental conditions. Mining these datasets requires efficient computational methods capable of integrating different types of data, identifying inter-relations between different components and inferring functional groups or 'modules' that shape intracellular processes. This study uses computational methods to delineate some of the mechanisms used by yeast cells to respond to environmental changes. The GRAM algorithm is first used to integrate gene expression data and ChIP-chip data in order to find modules of coexpressed and co-regulated genes as well as the transcription factors (TFs) that regulate these modules. Since transcription factors are themselves transcriptionally regulated, a three-layer regulatory cascade consisting of the TF-regulators, the TFs and the regulated modules is subsequently considered. This three-layer cascade is then modeled quantitatively using artificial neural networks (ANNs) where the input layer corresponds to the expression of the up-stream transcription factors (TF-regulators) and the output layer corresponds to the expression of genes within each module. This work shows that (a) the expression of at least 33 genes over time and for different stress conditions is well predicted by the expression of the top layer transcription factors, including cases in which the effect of up-stream regulators is shifted in time and (b) identifies at least 6 novel regulatory interactions that were not previously associated with stress-induced changes in gene expression. These findings suggest that the combination of gene expression and protein-DNA interaction data with artificial neural networks can successfully model biological pathways and capture quantitative dependencies between distant regulators and downstream genes.
Abstract: Restoration research has become important on principle recently in Czech Republic. The reason is simple. More than 70 % of mined brown coal comes from the North Bohemian Basin these days. Open cast brown coal mining has lead to large damage on the landscape. Reclamation of phytotoxic areas is one of the serious problems in the North Bohemian Basin. It mainly concerns the areas with the occurrence of overburden rocks from the coal bed enriched with coal. The presented paper includes the characteristics of the important phytotoxic areas and the methodology of their reclamation. The results are documented with the long term monitoring of physical, mineralogical, chemical and pedological parameters of rocks in the testing areas.
Abstract: Quantitative trait loci (QTL) experiments have yielded
important biological and biochemical information necessary for
understanding the relationship between genetic markers and
quantitative traits. For many years, most QTL algorithms only
allowed one observation per genotype. Recently, there has been an
increasing demand for QTL algorithms that can accommodate more
than one observation per genotypic distribution. The Bayesian
hierarchical model is very flexible and can easily incorporate this
information into the model. Herein a methodology is presented that
uses a Bayesian hierarchical model to capture the complexity of the
data. Furthermore, the Markov chain Monte Carlo model composition
(MC3) algorithm is used to search and identify important markers. An
extensive simulation study illustrates that the method captures the
true QTL, even under nonnormal noise and up to 6 QTL.
Abstract: Expression data analysis is based mostly on the
statistical approaches that are indispensable for the study of
biological systems. Large amounts of multidimensional data resulting
from the high-throughput technologies are not completely served by
biostatistical techniques and are usually complemented with visual,
knowledge discovery and other computational tools. In many cases,
in biological systems we only speculate on the processes that are
causing the changes, and it is the visual explorative analysis of data
during which a hypothesis is formed. We would like to show the
usability of multidimensional visualization tools and promote their
use in life sciences. We survey and show some of the
multidimensional visualization tools in the process of data
exploration, such as parallel coordinates and radviz and we extend
them by combining them with the self-organizing map algorithm. We
use a time course data set of transitional cell carcinoma of the bladder
in our examples. Analysis of data with these tools has the potential to
uncover additional relationships and non-trivial structures.
Abstract: Starting from a biologically inspired framework, Gabor filters were built up from retinal filters via LMSE algorithms. Asubset of retinal filter kernels was chosen to form a particular Gabor filter by using a weighted sum. One-dimensional optimization approaches were shown to be inappropriate for the problem. All model parameters were fixed with biological or image processing constraints. Detailed analysis of the optimization procedure led to the introduction of a minimization constraint. Finally, quantization of weighting factors was investigated. This resulted in an optimized cascaded structure of a Gabor filter bank implementation with lower computational cost.
Abstract: The purpose of present paper was to investigate
perceptions of Korean secondary school students about social issues
related to biological sciences. Twenty issues were selected based on
topics of articles in the newspaper from 2005 to 2010. The issues were
categorized into biotechnology, health-disease and environment
domains. Subjects were 541 high school students (male 253 and
female 288). On the survey, students were asked to answer on 5-point
Lickert scales how they thought of the effect of biological phenomena
or events related to biological issues on the individual life and the
society. They perceived that the biological issues would be more
effectible on the society than on the individual life. Female students
had a little more perceptions than males.
Abstract: Alpfa-fetoprotein and its fragments may be an important vehicle for targeted delivery of radionuclides to the tumor. We investigated the effect of conditions on the labeling of biologically active synthetic peptide based on the (F-afp) with technetium-99m. The influence of the nature of the buffer solution, pH, concentration of reductant, concentration of the peptide and the reaction temperature on the yield of labeling was examined. As a result, the following optimal conditions for labeling of (F-afp) are found: pH 8.5 (phosphate and bicarbonate buffers) and pH from 1.7 to 7.0 (citrate buffer). The reaction proceeds with sufficient yield at room temperature for 30 min at the concentration of SnCl2 and (Fafp) (F-afp) is to be less than 10 mkg/ml and 25 mkg/ml, respectively. Investigations of the test drug accumulation in the tumor cells of human breast cancer were carried out. Results can be assumed that the in vivo study of the (F-afp) in experimental tumor lesions will show concentrations sufficient for imaging these lesions by SPECT.
Abstract: As the web continues to grow exponentially, the idea
of crawling the entire web on a regular basis becomes less and less
feasible, so the need to include information on specific domain,
domain-specific search engines was proposed. As more information
becomes available on the World Wide Web, it becomes more difficult
to provide effective search tools for information access. Today,
people access web information through two main kinds of search
interfaces: Browsers (clicking and following hyperlinks) and Query
Engines (queries in the form of a set of keywords showing the topic
of interest) [2]. Better support is needed for expressing one's
information need and returning high quality search results by web
search tools. There appears to be a need for systems that do reasoning
under uncertainty and are flexible enough to recover from the
contradictions, inconsistencies, and irregularities that such reasoning
involves. In a multi-view problem, the features of the domain can be
partitioned into disjoint subsets (views) that are sufficient to learn the
target concept. Semi-supervised, multi-view algorithms, which
reduce the amount of labeled data required for learning, rely on the
assumptions that the views are compatible and uncorrelated. This
paper describes the use of semi-structured machine learning approach
with Active learning for the “Domain Specific Search Engines". A
domain-specific search engine is “An information access system that
allows access to all the information on the web that is relevant to a
particular domain. The proposed work shows that with the help of
this approach relevant data can be extracted with the minimum
queries fired by the user. It requires small number of labeled data and
pool of unlabelled data on which the learning algorithm is applied to
extract the required data.
Abstract: The prospective analysis is presented as an important tool to identify the most relevant opportunities and needs in research and development from planned interventions in innovation systems. This study chose Phyllanthus niruri, known as "stone break" to describe the knowledge about the specie, by using biotechnological forecasting through the software Vantage Point. It can be seen a considerable increase in studies on Phyllanthus niruri in recent years and that there are patents about this plant since twenty-five years ago. India was the country that most carried out research on the specie, showing interest, mainly in studies of hepatoprotection, antioxidant and anti-cancer activities. Brazil is in the second place, with special interest for anti-tumor studies. Given the identification of the Brazilian groups that exploit the species it is possible to mediate partnerships and cooperation aiming to help on the implementing of the Program of Herbal medicines (phytotherapics) in Brazil.