Abstract: Determining depth of anesthesia is a challenging problem
in the context of biomedical signal processing. Various methods
have been suggested to determine a quantitative index as depth of
anesthesia, but most of these methods suffer from high sensitivity
during the surgery. A novel method based on energy scattering of
samples in the wavelet domain is suggested to represent the basic
content of electroencephalogram (EEG) signal. In this method, first
EEG signal is decomposed into different sub-bands, then samples
are squared and energy of samples sequence is constructed through
each scale and time, which is normalized and finally entropy of the
resulted sequences is suggested as a reliable index. Empirical Results
showed that applying the proposed method to the EEG signals can
classify the awake, moderate and deep anesthesia states similar to
BIS.
Abstract: The present study was conducted to observe the effect
of Plantago psyllium on blood glucose and cholesterol levels in
normal and alloxan induced diabetic rats. To investigate the effect of
Plantago psyllium 40 rats were included in this study divided into
four groups of ten rats in each group. One group A was normal,
second group B was diabetic, third group C was non diabetic and
hypercholesterolemic and fourth group D was diabetic and
hypercholesterolemic. Two groups B and D were made diabetic by
intraperitonial injection of alloxan dissolved in 1mL distilled water at
a dose of 125mg/Kg of body weight. Two groups C and D were
made hypercholesterolemic by oral administration of powder
cholesterol (1g/Kg of body weight). The blood samples from all the
rats were collected from coccygial vein on 1st day, then on 21st and
42nd day respectively. All the samples were analyzed for blood
glucose and cholesterol level by using enzymatic kits. The blood
glucose and cholesterol levels of treated groups of rats showed
significant reduction after 7 weeks of treatment with Plantago
psyllium. By statistical analysis of results it was found that Plantago
psyllium has anti-diabetic and hypocholesterolemic activity in
diabetic and hypercholesterolemic albino rats.
Abstract: The effect of muscle loss due to transfemoral
amputation, on energy expenditure of hip joint and individual
residual muscles was simulated. During swing phase of gait, with
each muscle as an ideal force generator, the lower extremity was
modeled as a two-degree of freedom linkage, for which hip and knee
were joints. According to results, muscle loss will not lead to higher
energy expenditure of hip joint, as long as other parameters of limb
remain unaffected. This finding maybe due to the role of biarticular
muscles in hip and knee joints motion. Moreover, if hip flexors are
removed from the residual limb, residual flexors, and if hip extensors
are removed, residual extensors will do more work. In line with the
common practice in transfemoral amputation, this result demonstrates
during transfemoral amputation, it is important to maintain the length
of residual limb as much as possible.
Abstract: X-ray mammography is the most effective method for
the early detection of breast diseases. However, the typical diagnostic
signs such as microcalcifications and masses are difficult to detect
because mammograms are of low-contrast and noisy. In this paper, a
new algorithm for image denoising and enhancement in Orthogonal
Polynomials Transformation (OPT) is proposed for radiologists to
screen mammograms. In this method, a set of OPT edge coefficients
are scaled to a new set by a scale factor called OPT scale factor. The
new set of coefficients is then inverse transformed resulting in
contrast improved image. Applications of the proposed method to
mammograms with subtle lesions are shown. To validate the
effectiveness of the proposed method, we compare the results to
those obtained by the Histogram Equalization (HE) and the Unsharp
Masking (UM) methods. Our preliminary results strongly suggest
that the proposed method offers considerably improved enhancement
capability over the HE and UM methods.
Abstract: An electrocardiogram (ECG) feature extraction system
based on the calculation of the complex resonance frequency
employing Prony-s method is developed. Prony-s method is applied
on five different classes of ECG signals- arrhythmia as a finite sum
of exponentials depending on the signal-s poles and the resonant
complex frequencies. Those poles and resonance frequencies of the
ECG signals- arrhythmia are evaluated for a large number of each
arrhythmia. The ECG signals of lead II (ML II) were taken from
MIT-BIH database for five different types. These are the ventricular
couplet (VC), ventricular tachycardia (VT), ventricular bigeminy
(VB), and ventricular fibrillation (VF) and the normal (NR). This
novel method can be extended to any number of arrhythmias.
Different classification techniques were tried using neural networks
(NN), K nearest neighbor (KNN), linear discriminant analysis (LDA)
and multi-class support vector machine (MC-SVM).
Abstract: This research was carried out to determine the
possible effects of low electromagnetic field (EMF) exposure to the
developing mice fetuses. Pregnant mice were exposed to EMF
exposure at 0mT (sham) and 1.2 mT for six hours per session, carried
out on gestation day 3, 6, 9, 12 and 15. Samples from the stillborn
offspring were observed for morphological defects. The heart didn-t
show progressive cellular damage, the lungs were congested and
emphysemics. The bones were in advance stage of hypertrophy.
Spectrums of morphological defects were observed over 70% of the
surviving offspring. These results indicate that even at lower
exposure to low EMF, is enough to induce morphological defects in
prenatal mice.
Abstract: In this article, we propose a new surgical device for
circumferentially excision of high anal fistulas in a minimally
invasive manner. The new apparatus works on the basis of axially
rotating and moving a tubular blade along a fistulous tract
straightened using a rigid straight guidewire. As the blade moves
along the tract, its sharp circular cutting edge circumferentially
separates approximately 2.25 mm thickness of tract encircling the
rigid guidewire. We used the new set to excise two anal fistulas in a
62-year-old male patient, an extrasphincteric type and a long tract
with no internal opening. With regard to the results of this test, the
new device can be considered as a sphincter preserving mechanism
for treatment of high anal fistulas. Consequently, a major reduction
in the risk of fecal incontinence, recurrence rate, convalescence
period and patient morbidity may be achieved using the new device
for treatment of fistula-in-ano.
Abstract: In this paper, a wavelet-based neural network (WNN) classifier for recognizing EEG signals is implemented and tested under three sets EEG signals (healthy subjects, patients with epilepsy and patients with epileptic syndrome during the seizure). First, the Discrete Wavelet Transform (DWT) with the Multi-Resolution Analysis (MRA) is applied to decompose EEG signal at resolution levels of the components of the EEG signal (δ, θ, α, β and γ) and the Parseval-s theorem are employed to extract the percentage distribution of energy features of the EEG signal at different resolution levels. Second, the neural network (NN) classifies these extracted features to identify the EEGs type according to the percentage distribution of energy features. The performance of the proposed algorithm has been evaluated using in total 300 EEG signals. The results showed that the proposed classifier has the ability of recognizing and classifying EEG signals efficiently.
Abstract: Carbon tetrachloride (CCl4) is a well-known
hepatotoxin and exposure to this chemical is known to induce
oxidative stress and causes liver injury by the formation of free
radicals. Flacourtia indica commonly known as 'Baichi' has been
reported as an effective remedy for the treatment of a variety of
diseases. The objective of this study was to investigate the
hepatoprotective activity of aqueous extract of leaves of Flacourtia
indica against CCl4 induced hepatotoxicity. Animals were pretreated
with the aqueous extract of Flacourtia indica (250 & 500 mg/kg
body weight) for one week and then challenged with CCl4 (1.5 ml/kg
bw) in olive oil (1:1, v/v) on 7th day. Serum marker enzymes (ALP,
AST, ALT, Total Protein & Total Bilirubin) and TBARS level
(Marker for oxidative stress) were estimated in all the study groups.
Alteration in the levels of biochemical markers of hepatic damage
like AST, ALT, ALP, Total Protein, Total Bilirubin and lipid
peroxides (TBARS) were tested in both CCl4 treated and extract
treated groups. CCl4 has enhanced the AST, ALT, ALP and the
Lipid peroxides (TBARS) in liver. Treatment of aqueous extract of
Flacourtia indica leaves (250 & 500 mg/kg) exhibited a significant
protective effect by altering the serum levels of AST, ALT, ALP,
Total Protein, Total Bilirubin and liver TBARS. These biochemical
observations were supported by histopathological study of liver
sections. From this preliminary study it has been concluded that the
aqueous extract of the leaves of Flacourtia indica protects liver
against oxidative damages and could be used as an effective protector
against CCl4 induced hepatic damage. Our findings suggested that
Flacourtia indica possessed good hepatoprotective activity