Abstract: The aim of the present study was to evaluate the
mucoadhesion and the release of nicotinamide gel formulations using
in vitro methods. An agar plate technique was used to investigate the
adhesiveness of the gels whereas a diffusion apparatus was employed
to determine the release of nicotinamide from the gels. In this
respect, 10% w/w nicotinamide gels containing bioadhesive
polymers: Carbopol 934P (0.5-2% w/w), hydroxypropylmethyl
cellulose (HPMC) (4-10% w/w), sodium carboxymethyl cellulose
(SCMC) (4-6% w/w) and methylcellulose 4000 (MC) (3-5% w/w)
were prepared. The gel formulations had pH values in the range of
7.14 - 8.17, which were considered appropriate to oral mucosa
application. In general, the rank order of pH values appeared to be
SCMC > MC4000 > HPMC > Carbopol 934P. Types and
concentrations of polymers used somewhat affected the
adhesiveness. It was found that anionic polymers (Carbopol 934 and
SCMC) adhered more firmly to the agar plate than the neutral
polymers (HPMC and MC 4000). The formulation containing 0.5%
Carbopol 934P (F1) showed the highest release rate. With the
exception of the formulation F1, the neutral polymers tended to give
higher relate rates than the anionic polymers. For oral tissue
treatment, the optimum has to be balanced between the residence
time (adhesiveness) of the formulations and the release rate of the
drug. The formulations containing the anionic polymers: Carbopol
934P or SCMC possessed suitable physical properties (appearance,
pH and viscosity). In addition, for anionic polymer formulations,
justifiable mucoadhesive properties and reasonable release rates of
nicotinamide were achieved. Accordingly, these gel formulations
may be applied for the treatment of oral mucosal lesions.
Abstract: An ethical mandate of the social work profession in the
United States is that BSW and MSW graduates are sufficiently
prepared to both understand diverse cultural values and beliefs and
offer services that are culturally sensitive and relevant to clients. This
skill set is particularly important for social workers in the 21st Century,
given the increasing globalization of the U.S. and world. The purpose
of this paper is to outline a pedagogical model for teaching cultural
competency that resulted in a significant increase in cultural
competency for MSW graduates at Western Kentucky University
(WKU). More specifically, this model is predicated on five specific
culturally sensitive principles and activities that were found to be
highly effective in conveying culturally relevant knowledge and skills
to MSW students at WKU. Future studies can assess the effectiveness
of these principles in other MSW programs across the U.S. and abroad.
Abstract: The disaster from functional gastrointestinal disorders has detrimental impact on the quality of life of the effected population and imposes a tremendous social and economic burden. There are, however, rare diagnostic methods for the functional gastrointestinal disorders. Our research group identified recently that the gastrointestinal tract well in the patients with the functional gastrointestinal disorders becomes more rigid than healthy people when palpating the abdominal regions overlaying the gastrointestinal tract. Objective of current study is, therefore, identify feasibility of a diagnostic system for the functional gastrointestinal disorders based on ultrasound technique, which can quantify the characteristics above. Two-dimensional finite difference (FD) models (one normal and two rigid model) were developed to analyze the reflective characteristic (displacement) on each soft-tissue layer responded after application of ultrasound signals. The FD analysis was then based on elastic ultrasound theory. Validation of the model was performed via comparison of the characteristic of the ultrasonic responses predicted by FD analysis with that determined from the actual specimens for the normal and rigid conditions. Based on the results from FD analysis, ultrasound system for diagnosis of the functional gastrointestinal disorders was developed and clinically tested via application of it to 40 human subjects with/without functional gastrointestinal disorders who were assigned to Normal and Patient Groups. The FD models were favorably validated. The results from FD analysis showed that the maximum displacement amplitude in the rigid models (0.12 and 0.16) at the interface between the fat and muscle layers was explicitly less than that in the normal model (0.29). The results from actual specimens showed that the maximum amplitude of the ultrasonic reflective signal in the rigid models (0.2±0.1Vp-p) at the interface between the fat and muscle layers was explicitly higher than that in the normal model (0.1±0.2 Vp-p). Clinical tests using our customized ultrasound system showed that the maximum amplitudes of the ultrasonic reflective signals near to the gastrointestinal tract well for the patient group (2.6±0.3 Vp-p) were generally higher than those in normal group (0.1±0.2 Vp-p). Here, maximum reflective signals was appeared at 20mm depth approximately from abdominal skin for all human subjects, corresponding to the location of the boundary layer close to gastrointestinal tract well. These findings suggest that our customized ultrasound system using the ultrasonic reflective signal may be helpful to the diagnosis of the functional gastrointestinal disorders.
Abstract: In the package design industry, there are a lot of tacit knowledge resided within each designer. The objectives are to capture them and compile it to be used as a teaching resource and to create a video clip of package design process as well as to evaluate its quality and learning effectiveness. Interview were used as a technique for capturing knowledge in brand design concept, differentiation, recognition, rank of recognition factor, consumer survey, knowledge about marketing, research, graphic design, the effect of color, and law and regulation. Video clip about package design were created. The clip consisted of both the speech and clip of actual process. The quality of the video in term of media was ranked as good while the content was ranked as excellent. The students- score on post-test was significantly greater than that of pretest (p>0.001).
Abstract: Availability of raw materials is important for
Indonesia as a furniture exporting country. Teak log as raw materials
is supplied to the furniture industry by Perum Perhutani (PP). PP
needs to involve carbon trading for nature conservation. PP also has
an obligation in the Corporate Social Responsibility program. PP and
furniture industry also must prosecute the regulations related to
ecological issues and labor rights. This study has the objective to
create the relationship model between supplier and manufacturer to
fulfill teak log demand that involving teak forest carbon
sequestration. A model is formulated as Goal Programming to get the
favorable solution for teak log procurement and support carbon
sequestration that considering economical, ecological, and social
aspects of both supplier and manufacturer. The results show that the
proposed model can be used to determine the teak log quantity
involving carbon trading to achieve the seven goals to be satisfied the
sustainability considerations.
Abstract: Number Link is a Japanese logic puzzle where pairs of same numbers are connected using lines. Number Link can be regarded as a dynamic multiple travelers, multiple entries and exits maze, where the walls and passages are dynamically changing as the travelers move. In this paper, we apply the Tremaux’s algorithm to solve Number Link puzzles of size 8x8, 10x10 and 15x20. The algorithm works well and produces a solution for puzzles of size 8x8 and 10x10. However, solving a puzzle of size 15x20 requires high computer processing power and is time consuming.
Abstract: In this study, we consider a special situation that only a pair of hydrophone on a moving underwater vehicle is available to localize a fixed acoustic source of far distance. The trigonometry can be used in this situation by using two different DOA of different locations. Notice that the distance between the two locations should be measured. Therefore, we assume that the vehicle is sailing straightly and the moving distance for each unit time is measured continuously. However, the accuracy of the localization using the trigonometry is highly dependent to the accuracy of DOAs and measured moving distances. Therefore, we proposed another method based on the extended Kalman filter that gives more robust and accurate localization result.
Abstract: The increase on the demand of IT resources diverts
the enterprises to use the cloud as a cheap and scalable solution.
Cloud computing promises achieved by using the virtual machine as a
basic unite of computation. However, the virtual machine pre-defined
settings might be not enough to handle jobs QoS requirements. This
paper addresses the problem of mapping jobs have critical start
deadlines to virtual machines that have predefined specifications.
These virtual machines hosted by physical machines and shared a
fixed amount of bandwidth. This paper proposed an algorithm that
uses the idle virtual machines bandwidth to increase the quote of other
virtual machines nominated as executors to urgent jobs. An algorithm
with empirical study have been given to evaluate the impact of the
proposed model on impatient jobs. The results show the importance
of dynamic bandwidth allocation in virtualized environment and its
affect on throughput metric.
Abstract: Surface sediment samples were collected from the
Canon River mouth, Taiwan and analyzed for polycyclic aromatic
hydrocarbons (PAHs). Total PAHs concentrations varied from 337 to
1,252 ng/g dry weight, with a mean concentration of 827 ng/g dry
weight. The spatial distribution of PAHs reveals that the PAHs
concentration is relatively high in the river mouth region, and
gradually diminishes toward the harbor region. Diagnostic ratios
showed that the possible source of PAHs in the Canon River mouth
could be petroleum combustion. The toxic equivalent concentrations
(TEQcarc) of PAHs varied from 47 to 112 ng TEQ/g dry weight. Higher
total TEQcarc values were found in the river mouth region. As
compared with the US Sediment Quality Guidelines (SQGs), the
observed levels of PAHs at Canon River mouth were lower than the
effects range low (ERL), and would probably not exert adverse
biological effects.
Abstract: The impact force of a rockfall is mainly determined by
its moving behavior and velocity, which are contingent on the rock
shape, slope gradient, height, and surface roughness of the moving
path. It is essential to precisely calculate the moving path of the
rockfall in order to effectively minimize and prevent damages caused
by the rockfall. By applying the Colorado Rockfall Simulation
Program (CRSP) program as the analysis tool, this research studies the
influence of three shapes of rock (spherical, cylindrical and discoidal)
and surface roughness on the moving path of a single rockfall. As
revealed in the analysis, in addition to the slope gradient, the geometry
of the falling rock and joint roughness coefficient ( JRC ) of the slope
are the main factors affecting the moving behavior of a rockfall. On a
single flat slope, both the rock-s bounce height and moving velocity
increase as the surface gradient increases, with a critical gradient value
of 1:m = 1 . Bouncing behavior and faster moving velocity occur more
easily when the rock geometry is more oval. A flat piece tends to cause
sliding behavior and is easily influenced by the change of surface
undulation. When JRC
Abstract: The 15-a-side Fiji rugby team trains well in preparations for any rugby competition but rarely performs to expectations. In order to help the Fiji local based rugby players to identify some key basic areas in improving their performance, a series of workshops were conducted to assess their nutritional status and dietary habits in relation to energy demand during rugby matches. The nutrition workshop included the administration of questionnaires to 19 local based rugby players, requesting the following information: usual food intakes, training camp food intakes, carbohydrate loading, pre-game meals and post-game meals. The study revealed that poor eating habits of the players resulted in the low carbohydrate intake, which may have contributed to increase levels of fatigue leading to loss of stamina even before the second half of the game. It appears that the diet of most 15-a-side players does not provide enough energy to enable them to last the full eightyminutes of the game.
Abstract: Both the minimum energy consumption and
smoothness, which is quantified as a function of jerk, are generally
needed in many dynamic systems such as the automobile and the
pick-and-place robot manipulator that handles fragile equipments.
Nevertheless, many researchers come up with either solely
concerning on the minimum energy consumption or minimum jerk
trajectory. This research paper considers the indirect minimum Jerk
method for higher order differential equation in dynamics
optimization proposes a simple yet very interesting indirect jerks
approaches in designing the time-dependent system yielding an
alternative optimal solution. Extremal solutions for the cost functions
of indirect jerks are found using the dynamic optimization methods
together with the numerical approximation. This case considers the
linear equation of a simple system, for instance, mass, spring and
damping. The simple system uses two mass connected together by
springs. The boundary initial is defined the fix end time and end
point. The higher differential order is solved by Galerkin-s methods
weight residual. As the result, the 6th higher differential order shows
the faster solving time.
Abstract: Selected Mapping (SLM) is a PAPR reduction technique, which converts the OFDM signal into several independent signals by multiplication with the phase sequence set and transmits one of the signals with lowest PAPR. But it requires the index of the selected signal i.e. side information (SI) to be transmitted with each OFDM symbol. The PAPR reduction capability of the SLM scheme depends on the selection of phase sequence set. In this paper, we have proposed a new phase sequence set generation scheme based on M-ary chaotic sequence and a mapping scheme to map quaternary data to concentric circle constellation (CCC) is used. It is shown that this method does not require SI and provides better SER performance with good PAPR reduction capability as compared to existing SLMOFDM methods.
Abstract: A novel physico-chemical route to produce few layer graphene nanoribbons with atomically smooth edges is reported, via acid treatment (H2SO4:HNO3) followed by characteristic thermal shock processes involving extremely cold substances. Samples were studied by scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), Raman spectroscopy and X-ray photoelectron spectroscopy. This method demonstrates the importance of having the nanotubes open ended for an efficient uniform unzipping along the nanotube axis. The average dimensions of these nanoribbons are approximately ca. 210 nm wide and consist of few layers, as observed by transmission electron microscopy. The produced nanoribbons exhibit different chiralities, as observed by high resolution transmission electron microscopy. This method is able to provide graphene nanoribbons with atomically smooth edges which could be used in various applications including sensors, gas adsorption materials, composite fillers, among others.
Abstract: In this study, we used shape memory alloys as
actuators to build a biomorphic robot which can imitate the motion of
an earthworm. The robot can be used to explore in a narrow space.
Therefore we chose shape memory alloys as actuators. Because of the
small deformation of a wire shape memory alloy, spiral shape memory
alloys are selected and installed both on the X axis and Y axis (each
axis having two shape memory alloys) to enable the biomorphic robot
to do reciprocating motion. By the mechanism we designed, the robot
can increase the distance as it moves in a duty cycle. In addition, two
shape memory alloys are added to the robot head for controlling right
and left turns. By sending pulses through the I/O card from the
controller, the signals are then amplified by a driver to heat the shape
memory alloys in order to make the SMA shrink to pull the mechanism
to move.
Abstract: An inverse geometry problem is solved to predict an
unknown irregular boundary profile. The aim is to minimize the
objective function, which is the difference between real and
computed temperatures, using three different versions of Conjugate
Gradient Method. The gradient of the objective function, considered
necessary in this method, obtained as a result of solving the adjoint
equation. The abilities of three versions of Conjugate Gradient
Method in predicting the boundary profile are compared using a
numerical algorithm based on the method. The predicted shapes show
that due to its convergence rate and accuracy of predicted values, the
Powell-Beale version of the method is more effective than the
Fletcher-Reeves and Polak –Ribiere versions.
Abstract: Our adaptive multimodal system aims at correctly
presenting a mathematical expression to visually impaired users.
Given an interaction context (i.e. combination of user, environment
and system resources) as well as the complexity of the expression
itself and the user-s preferences, the suitability scores of different
presentation format are calculated. Unlike the current state-of-the art
solutions, our approach takes into account the user-s situation and not
imposes a solution that is not suitable to his context and capacity. In
this wok, we present our methodology for calculating the
mathematical expression complexity and the results of our
experiment. Finally, this paper discusses the concepts and principles
applied on our system as well as their validation through cases
studies. This work is our original contribution to an ongoing research
to make informatics more accessible to handicapped users.
Abstract: This paper addresses the controller synthesis problem of discrete-time switched positive systems with bounded time-varying delays. Based on the switched copositive Lyapunov function approach, some necessary and sufficient conditions for the existence of state-feedback controller are presented as a set of linear programming and linear matrix inequality problems, hence easy to be verified. Another advantage is that the state-feedback law is independent on time-varying delays and initial conditions. A numerical example is provided to illustrate the effectiveness and feasibility of the developed controller.
Abstract: This paper describes reactive neural control used to
generate phototaxis and obstacle avoidance behavior of walking
machines. It utilizes discrete-time neurodynamics and consists of
two main neural modules: neural preprocessing and modular neural
control. The neural preprocessing network acts as a sensory fusion
unit. It filters sensory noise and shapes sensory data to drive the
corresponding reactive behavior. On the other hand, modular neural
control based on a central pattern generator is applied for locomotion
of walking machines. It coordinates leg movements and can generate
omnidirectional walking. As a result, through a sensorimotor loop this
reactive neural controller enables the machines to explore a dynamic
environment by avoiding obstacles, turn toward a light source, and
then stop near to it.
Abstract: Master plan is a tool to guide and manage the growth of cities in a planned manner. The soul of a master plan lies in its implementation framework. If not implemented, people are trapped in a mess of urban problems and laissez-faire development having serious long term repercussions. Unfortunately, Master Plans prepared for several major cities of Pakistan could not be fully implemented due to host of reasons and Lahore is no exception. Being the second largest city of Pakistan with a population of over 7 million people, Lahore holds the distinction that the first ever Master Plan in the country was prepared for this city in 1966. Recently in 2004, a new plan titled `Integrated Master Plan for Lahore-2021- has been approved for implementation. This paper provides a comprehensive account of the weaknesses and constraints in the plan preparation process and implementation strategies of Master Plans prepared for Lahore. It also critically reviews the new Master Plan particularly with respect to the proposed implementation framework. The paper discusses the prospects and pre-conditions for successful implementation of the new Plan in the light of historic analysis, interviews with stakeholders and the new institutional context under the devolution plan.