Abstract: A simple, accurate and precise direct spectrophotometric method has been developed for the determination of cefixime in tablets and capsules. The method is based on the reaction of cefixime with a mixture of potassium iodide and potassium iodate to form yellow coloured product in ethanol-distilled water medium at room temperature which absorbed maximally at 352 nm. The factors affecting the reaction product were carefully studied and optimized. The validation parameters based on International Conference on Harmonisation (ICH, USA) guidelines were followed. The effect of common excipients used as additives has been tested and the tolerance limit was calculated for the determination of cefixime. Beer’s law is obeyed in the concentration range of 4 – 24 ug mL-1 with apparent molar absorptivity of 1.52 × 104 L mol-1cm-1 and Sandell’s sensitivity of 0.033 ug/cm2/ 0.001 absorbance unit. The limits of detection and quantitation for the proposed method are 0.32 and 1.06 ug mL-1, respectively. The proposed method has been successfully applied for the determination of cefixime in pharmaceutical formulations. The results obtained by the proposed method were statistically compared with the reference method using t- and F- values and found no significant difference between the two methods. The proposed method can be used as an alternate method for routine quality control analysis of cefixime in pharmaceutical formulations.
Abstract: This paper presents a comparison of the reference
management software between Zotero and Mendeley and the results
were drawn by comparing the two software’s. The novelty of this
paper is the comparative analysis of the software and it has shown
that Mendeley can import more information from the Google Scholar
for the researchers. This finding can help to know researchers to use
the reference management software.
Abstract: Malathion (ML) is a well known pesticide commonly
used in many agricultural and non-agricultural processes. Its toxicity
has been attributed primarily to the accumulation of acetylcholine
(Ach) at nerve junctions, due to the inhibition of acetylcholinesterase
(AChE). The aim of the current research was to study the protective
effect of the melissa plant extract against reproductive impairment
induced by malathion in 32 male albino rats, and the biological
experiment was divided into four groups (8 in each) that given
malathion (27 mg/kg; 1/50 of the LD50 for an oral dose) and/or
Melissa officinalis (MO) extract (200mg/kg/day) by gavages
technique. The sperm counts, sperm motility, sperm morphology,
FSH, LH, and testosterone levels had been determined in testes
homogenate at the end of the experiment. It is worthy to report that,
rats treated with melissa extract did not show a significant difference
when compared with the control group, while rats given malathion
alone had significantly lower sperm count, sperm motility, and
significantly higher abnormal sperm numbers, than the untreated
control rats as well as having significantly lower serum FSH, LH, and
testosterone levels compared with the control group. Administrations
of melissa extract restore all mentioned histological parameters
towards the control group and the melissa extract had a strong
positive protective effect against malathion toxicity. Results the of
biological parameters were confirmed by the histological
examination of rat testes and indicated that, both control and melissa
groups showing normal seminiferous tubules, while malathion group
testicular tissues had necrosis, edema in the seminiferous tubules and
degeneration of spermatogonial cells lining the seminiferous tubules
with incomplete spermatogenesis. The use of melissa against
malathion improved the histological picture and showing normal
seminiferous tubules with complete spermatogenesis and almost there
was no histopathological changes could be noted.
Abstract: Pomegranate (Punica granatum L.) is an ancient fruit of great medical interest and rich source of antioxidants. Pesticides as dimethoate play a crucial role in the occurrence many diseases in plants, animal and human. Therefore the ability of Pomegranate (Punica granatum L.) to alleviate hepatotoxicity induced by organophosphate pesticide dimethoate was investigated. Albino male rats were divided randomly into 4 groups and kept at 7 animals per group in an environmentally controlled condition for 6 weeks. The first group was served as a control group (basal diet), the second group fed on basal diet supplemented with 5% freeze dried pomegranate seeds, the third group fed on 20 ppm dimethoate contaminated diet and the last group fed on dimethoate contaminated diet supplemented with 5% freeze dried pomegranate seeds. The results revealed that administration of dimethoate caused high significant increased in liver functions: alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP) activities as well as lipid peroxide (malonaldhyde, MDA); on the other hand high significant decreased on glutathione (GSH), glutathione peroxidase (GPx), albumin and total protein were observed. However addition of 5% freeze dried pomegranate seeds significantly improved all previously mentioned parameters. These results indicate the dimethoate induced hepatotoxicity and highlight the protective effect of pomegranate seeds as a potential protective agent against dimethoate induced hepatotoxicity. This may be attributed to the powerful antioxidants (polyphenols, total phenols, and total flavonoids) which present in high levels in pomegranate as well as improving the immunity by activation of antioxidant enzymes GSH and GPx.
Abstract: The system is designed to show images which are
related to the query image. Extracting color, texture, and shape
features from an image plays a vital role in content-based image
retrieval (CBIR). Initially RGB image is converted into HSV color
space due to its perceptual uniformity. From the HSV image, Color
features are extracted using block color histogram, texture features
using Haar transform and shape feature using Fuzzy C-means
Algorithm. Then, the characteristics of the global and local color
histogram, texture features through co-occurrence matrix and Haar
wavelet transform and shape are compared and analyzed for CBIR.
Finally, the best method of each feature is fused during similarity
measure to improve image retrieval effectiveness and accuracy.
Abstract: The paper a summary of the results of concretes with
partial substitution of natural aggregates with recycled concrete is
solved. Design formulas of the concretes were characterised with 20,
40 and 60% substitution of natural 8-16mm fraction aggregates with
a selected recycled concrete of analogous coarse fractions. With the
product samples an evaluation of coarse fraction aggregates influence
on fresh concrete consistency and concrete strength in time was
carried out. The results of concretes with aggregates substitution will
be compared to reference formula containing only the fractions of
natural aggregates.
Abstract: Anultra-low power capacitor less low-dropout voltage
regulator with improved transient response using gain enhanced feed
forward path compensation is presented in this paper. It is based on a
cascade of a voltage amplifier and a transconductor stage in the feed
forward path with regular error amplifier to form a composite gainenhanced
feed forward stage. It broadens the gain bandwidth and thus
improves the transient response without substantial increase in power
consumption. The proposed LDO, designed for a maximum output
current of 100 mA in UMC 180 nm, requires a quiescent current of
69 )A. An undershot of 153.79mV for a load current changes from
0mA to 100mA and an overshoot of 196.24mV for current change of
100mA to 0mA. The settling time is approximately 1.1 )s for the
output voltage undershooting case. The load regulation is of 2.77
)V/mA at load current of 100mA. Reference voltage is generated by
using an accurate band gap reference circuit of 0.8V.The costly
features of SOC such as total chip area and power consumption is
drastically reduced by the use of only a total compensation
capacitance of 6pF while consuming power consumption of 0.096
mW.
Abstract: The article presents the results of the application of
artificial neural networks to separate the fluorescent contribution of
nanodiamonds used as biomarkers, adsorbents and carriers of drugs
in biomedicine, from a fluorescent background of own biological
fluorophores. The principal possibility of solving this problem is
shown. Use of neural network architecture let to detect fluorescence
of nanodiamonds against the background autofluorescence of egg
white with high accuracy - better than 3 ug/ml.
Abstract: This paper presents the performance state analysis of
Self-Excited Induction Generator (SEIG) using Artificial Bee Colony
(ABC) optimization technique. The total admittance of the induction
machine is minimized to calculate the frequency and magnetizing
reactance corresponding to any rotor speed, load impedance and
excitation capacitance. The performance of SEIG is calculated using
the optimized parameter found. The results obtained by ABC
algorithm are compared with results from numerical method. The
results obtained coincide with the numerical method results. This
technique proves to be efficient in solving nonlinear constrained
optimization problems and analyzing the performance of SEIG.
Abstract: Concerns on corrosion and effective coating
protection of double hull tankers and bulk carriers in service have
been raised especially in water ballast tanks (WBTs). Test
protocols/methodologies specifically that which is incorporated in the
International Maritime Organisation (IMO), Performance Standard
for Protective Coatings for Dedicated Sea Water ballast tanks (PSPC)
are being used to assess and evaluate the performance of the coatings
for type approval prior to their application in WBTs. However, some
of the type approved coatings may be applied as very thick films to
less than ideally prepared steel substrates in the WBT. As such films
experience hygrothermal cycling from operating and environmental
conditions, they become embrittled which may ultimately result in
cracking. This embrittlement of the coatings is identified as an
undesirable feature in the PSPC but is not mentioned in the test
protocols within it. There is therefore renewed industrial research
aimed at understanding this issue in order to eliminate cracking and
achieve the intended coating lifespan of 15 years in good condition.
This paper will critically review test protocols currently used for
assessing and evaluating coating performance, particularly the IMO
PSPC.
Abstract: Azadirachta excelsa or locally known as sentang are
frequently used as a traditional medicine by diabetes patients in
Malaysia. However, less attention has been given to their toxicity
effect. Thus, the study is an attempt to examine the protective effect
of A. excelsa on the pancreas and to determine possible toxicity
mediated by the extract. Diabetes was induced experimentally in rats
by high-fat-diet for 16 weeks followed by intraperitoneal injection of
streptozotocin at dosage of 35 mg/kg of body weight. Declination of
the fasting blood glucose level was observed after continuous
administration of A. excelsa for 14 days twice daily. This is due to the
refining structure of the pancreas. However, surprisingly, the plant
extract reduced the leukocytes, erythrocytes, hemoglobin, MCHC and
lymphocytes. In addition, the rat treated with the plant extract
exhibited increment in AST and eosinocytes level. Overall, the
finding shows that A. excelsa possesses antidiabetic activity by
improving the structure of pancreatic islet of Langerhans but
involved in ameliorating of hematology and biochemical parameters.
Abstract: This work presents the modelling and simulation of
saponification of ethyl acetate in the presence of sodium hydroxide in
a plug flow reactor using Aspen Plus simulation software. Plug flow
reactors are widely used in the industry due to the non-mixing
property. The use of plug flow reactors becomes significant when
there is a need for continuous large scale reaction or fast reaction.
Plug flow reactors have a high volumetric unit conversion as the
occurrence for side reactions is minimum. In this research Aspen Plus
V8.0 has been successfully used to simulate the plug flow reactor. In
order to simulate the process as accurately as possible HYSYS Peng-
Robinson EOS package was used as the property method. The results
obtained from the simulation were verified by the experiment carried
out in the EDIBON plug flow reactor module. The correlation
coefficient (r2) was 0.98 and it proved that simulation results
satisfactorily fit for the experimental model. The developed model
can be used as a guide for understanding the reaction kinetics of a
plug flow reactor.
Abstract: Lead (Pb) poisoning is one of the most common and
preventable environmental health problems. There are different
sources of environmental pollution with lead as lead alkyl additives
in petrol and manufacturing processes. Pb in the atmosphere can be
deposited in urban soils, and may then be re-suspended to re-enter the
atmosphere. This could increase human exposure to Pb and cause
long-term health effects. Thus, monitoring Pb pollution is considered
one of the major tasks in controlling pollution. Scalp hair can be
utilized for the determination of lead (Pb) concentration. It provides a
lasting record of metal intakes of weeks or even months, and for most
metals, their accumulation in hair reflects their accumulation in the
whole body. This work was conducted to investigate the
concentration of lead in male scalp hair of Cairo (residential-traffic
and residential-industrial) and rural residents after twenty years of
phasing out of leaded gasoline. Results indicated that the mean
concentration of lead in hair of residential-traffic (9.7552 μg/g ±0.71)
and residential-industrial (12.3288 μg/g ±1.13) was significantly
higher than that in rural residents (4.7327 μg/g ±0.67). The mean
concentration of lead in hair of resident’s industrial areas was the
highest among Cairo residents and not the traffic areas as it was
before phasing out of leaded gasoline. Twenty years of phasing out of
leaded gasoline in Cairo has greatly improved the lead pollution
among residents of traffic areas, but industrial areas residents were
still suffering from lead pollution, which needs more efforts to
control the sources of lead pollution.
Abstract: Roof top rainwater harvesting (RWH) has been
carried out worldwide to provide an inexpensive source of water for
many people. This research aims at evaluating the potential of roof
top rain water harvesting as a resource in Jordan. For the purpose of
this work, two case studies at Al-Jubiha and Shafa-Badran districts in
Amman city were selected. All existing rooftops in both districts
were identified by digitizing 2012 satellite images of the two districts
using Google earth and ArcGIS tools. Rational method was used to
estimate the potential volume of rainwater that can be harvested from
the digitized rooftops. Results indicated that 1.17 and 0.526 MCM/yr
can be harvested in Al-Jubiha and Shafa-Badran districts,
respectively. This study should increase the attention to the
importance of implementing RWH technique in Jordanian residences
as a viable alternative for ensuring a continued source of non-potable
water.
Abstract: In the present work, detailed analysis on flow characteristics of a pair of immiscible liquids through horizontal pipeline is simulated by using ANSYS FLUENT 6.2. Moderately viscous oil and water (viscosity ratio = 107, density ratio = 0.89 and interfacial tension = 0.024 N/m) have been taken as system fluids for the study. Volume of Fluid (VOF) method has been employed by assuming unsteady flow, immiscible liquid pair, constant liquid properties, and co-axial flow. Meshing has been done using GAMBIT. Quadrilateral mesh type has been chosen to account for the surface tension effect more accurately. From the grid independent study, we have selected 47037 number of mesh elements for the entire geometry. Simulation successfully predicts slug, stratified wavy, stratified mixed and annular flow, except dispersion of oil in water, and dispersion of water in oil. Simulation results are validated with horizontal literature data and good conformity is observed. Subsequently, we have simulated the hydrodynamics (viz., velocity profile, area average pressure across a cross section and volume fraction profile along the radius) of stratified wavy and annular flow at different phase velocities. The simulation results show that in the annular flow, total pressure of the mixture decreases with increase in oil velocity due to the fact that pipe cross section is completely wetted with water. Simulated oil volume fraction shows maximum at the centre in core annular flow, whereas, in stratified flow, maximum value appears at upper side of the pipeline. These results are in accord with the actual flow configuration. Our findings could be useful in designing pipeline for transportation of crude oil.
Abstract: Abundant and cheap agricultural waste of oil palm trunk (OPT) juice was used to produce bioethanol. Two strains of Saccharomyces cerevisiae and a strain of Pichia stipitis were used to produce bioethanol from the OPT juice. Fermentation was conducted at previously optimized condition at 30oC and without shaking. The kinetic parameters were estimated and calculated. Monod equation and Hinshelwood model is used to relate the specific growth to the concentration of the limiting substrate and also to simulate bioethanol production rate. Among the three strains, single S. cerevisiae Kyokai no. 7 produce the highest ethanol yield of 0.477 g/l.h within the shortest time (12 h). This yeast also produces more than 20 g/l ethanol concentration within 10 h of fermentation.
Abstract: Attractive and creative advertisement displays are
often in high demand as they are known to have profound impact on
the commercial market. In the fast advancement of technology,
advertising trend has taken a great leap in attracting more and more
demanding consumers. A low-cost and low-power consumption
flipping advertisement board has been developed in this paper. The
design of the electrical circuit and the controller of the advertisement
board are presented. A microcontroller, a Darlington Pair driver and a
unipolar stepper motor were used to operate the electrical flipping
advertisement board. The proposed system has been implemented
and the hardware has been tested to demonstrate the capability of
displaying multiple advertisements in a panel.
Abstract: This article deals with the perceived quality of regional products in the Moravian-Silesian region in the Czech Republic. Research was focused on finding out what do consumers perceive as a quality product and what characteristics make a quality product. The data were obtained by questionnaire survey andanalysed by IBM SPSS. From the thousands of respondents the representative sample of 719 for MS region was created based on demographic factors of gender, age, education and income. The research analysis disclosed that consumers in MS region are still price oriented and that the preference of quality over price does not depend on regional brand knowledge.
Abstract: Analytical expressions of the current and angular errors, as well as the frequency characteristics of an induction converter describing the relation with its structural parameters, the core and winding characteristics are obtained. Based on estimation of the dependences obtained, a mathematical problem of parametric optimization is formulated which can successfully be used for investigating and diagnosing an induction converter.
Abstract: The use of low quality concrete has been identified as one of the main causes of the incessant collapse of buildings in Nigeria. Emphasis has been on the use of poor quality aggregates, poor workmanship and the use of lean concrete mix with low cement quantity as the reasons for the low quality of concrete used for building construction in Nigeria. Surveys conducted revealed that in the construction of most privately owned buildings where concrete trial mixes and concrete compressive strength quality assurance tests are not conducted, concretes used for building constructions are produced using the 1:2:4 mix ratio irrespective of the cement grade/strength class. In this paper, the possible role of the use of inappropriate cement grade/strength class as a cause of the incessant collapse of building in Nigeria is investigated. Investigation revealed that the compressive strengths of concrete cubes produced with Portland-limestone cement grade 32.5 using 1:2:4 and 1:1.5:3 mix ratios are less than the 25MPa and 30MPa cube strengths generally recommended for building superstructures and foundations respectively. Conversely, the compressive strengths of concrete cubes produced with Portland-limestone cement grade 42.5 using 1:2:4 and 1:1.5:3 mix ratios exceed the 25MPa and 30MPa generally recommended for building superstructures and foundations respectively. Thus, it can be concluded that the use of inappropriate cement grade (Portland-limestone cement grade 32.5), particularly for the construction of building foundations is a potential cause of the incessant collapse of buildings in Nigeria. It is recommended that the Standards Organisation of Nigeria should embark on creating awareness for Nigerians, particularly, the home owners and the roadside craftsmen that Portland-limestone cement grade 32.5 should not be used for the construction of building load-carrying members, particularly, building foundations in order to reduce the incessant incidence of collapsed building.