Abstract: Medical imaging produces human body pictures in
digital form. Since these imaging techniques produce prohibitive
amounts of data, compression is necessary for storage and
communication purposes. Many current compression schemes
provide a very high compression rate but with considerable loss of
quality. On the other hand, in some areas in medicine, it may be
sufficient to maintain high image quality only in region of interest
(ROI). This paper discusses a contribution to the lossless
compression in the region of interest of Scintigraphic images based
on SPIHT algorithm and global transform thresholding using
Huffman coding.