Abstract: Tumor cells have an invasive and metastatic phenotype
that is the main cause of death for cancer patients. Tumor
establishment and penetration consists of a series of complex
processes involving multiple changes in gene expression. In this study,
intraperitoneal administration of a high concentration of ascorbic acid
inhibited tumor establishment and decreased tumor mass in BALB/C
mice implanted with S-180 sarcoma cancer cells. To identify proteins
involved in the ascorbic acid-mediated inhibition of tumor
progression, changes in the tumor proteome associated with ascorbic
acid treatment of BALB/C mice implanted with S-180 were
investigated using two-dimensional gel electrophoresis and mass
spectrometry. Twenty protein spots were identified whose expression
was different between control and ascorbic acid treatment groups.
Abstract: terrorism and extremism are among the most
dangerous and difficult to forecast the phenomena of our time, which
are becoming more diverse forms and rampant. Terrorist attacks often
produce mass casualties, involve the destruction of material and
spiritual values, beyond the recovery times, sow hatred among
nations, provoke war, mistrust and hatred between the social and
national groups, which sometimes can not be overcome within a
generation. Currently, the countries of Central Asia are a topical issue
– the threat of terrorism and religious extremism, which grow not
only in our area, but throughout the world. Of course, in each of the
terrorist threat is assessed differently. In our country the problem of
terrorism should not be acutely. Thus, after independence and
sovereignty of Kazakhstan has chosen the path of democracy,
progress and free economy. With the policy of the President of
Kazakhstan Nursultan Nazarbayev and well-organized political and
economic reforms, there has been economic growth and rising living
standards, socio-political stability, ensured civil peace and accord in
society [1].
Abstract: This paper presents an application of Artificial Neural Network (ANN) to forecast actual cost of a project based on the earned value management system (EVMS). For this purpose, some projects randomly selected based on the standard data set , and it is produced necessary progress data such as actual cost ,actual percent complete , baseline cost and percent complete for five periods of project. Then an ANN with five inputs and five outputs and one hidden layer is trained to produce forecasted actual costs. The comparison between real and forecasted data show better performance based on the Mean Absolute Percentage Error (MAPE) criterion. This approach could be applicable to better forecasting the project cost and result in decreasing the risk of project cost overrun, and therefore it is beneficial for planning preventive actions.
Abstract: In this paper challenges associated with a new
generation of Computer Science students are examined. The mode of
education in tertiary institutes has progressed slowly while the needs
of students have changed rapidly in an increasingly technological
world. The major learning paradigms and learning theories within
these paradigms are studied to find a suitable strategy for educating
modern students. These paradigms include Behaviourism,
Constructivism, Humanism and Cogntivism. Social Learning theory
and Elaboration theory are two theories that are further examined and
a survey is done to determine how these strategies will be received by
students. The results and findings are evaluated and indicate that
students are fairly receptive to a method that incorporates both Social
Learning theory and Elaboration theory, but that some aspects of all
paradigms need to be implemented to create a balanced and effective
strategy with technology as foundation.
Abstract: Through the course of this paper we outline how
mobile Business Intelligence (m-BI) can help businesses to work
smarter and to improve their agility. When we analyze the industry
from the usage perspective or how interaction with the enterprise BI
system happens via mobile devices, we may easily understand that
there are two major types of mobile BI: passive and active. Active
mobile BI gives provisions for users to interact with the BI systems
on-the-fly. Active mobile business intelligence often works as a
combination of both “push and pull" techniques. Some mistakes were
done in the up-to-day progress of mobile technologies and mobile BI,
as well as some problems that still have to be resolved. We discussed
in the paper rather broadly.
Abstract: Simulation accuracy by recent dynamic vehicle
simulation multidimensional expression significantly has progressed
and acceptable results not only for passive vehicles but also for
active vehicles normally equipped with advanced electronic
components is also provided. Recently, one of the subjects that has it
been considered, is increasing the safety car in design. Therefore,
many efforts have been done to increase vehicle stability especially
in the turn. One of the most important efforts is adjusting the camber
angle in the car suspension system. Optimum control camber angle in
addition to the vehicle stability is effective in the wheel adhesion on
road, reducing rubber abrasion and acceleration and braking. Since
the increase or decrease in the camber angle impacts on the stability
of vehicles, in this paper, a car suspension system mechanism is
introduced that could be adjust camber angle and the mechanism is
application and also inexpensive. In order to reach this purpose, in
this paper, a passive double wishbone suspension system with
variable camber angle is introduced and then variable camber
mechanism designed and analyzed for study the designed system
performance, this mechanism is modeled in Visual Nastran software
and kinematic analysis is revealed.
Abstract: Education in the modern world provides the socioeconomic
progress of society. In today's society, where the presence
of large middle class ensures its stability and is a symbol of
resolution of hidden economic problems, education is an integral part
of formation and reproduction of the middle class. This article presents part of results of the sociological study conducted under the
project "Kazakhstan model of education: international experience and national traditions" supported by the Foundation of the First President
of Republic of Kazakhstan - Leader of the Nation to determine the
ratio of students to the transformations of the educational system. The
authors conclude that the Kazakhstani system of education, passing
through the transformation processes, improving the quality of
educational programs and trying to correspond to the international
standards, not yet in full range, but begins to perform important
functions in the formation of the middle class.
Abstract: The electronically available Urdu data is in image form
which is very difficult to process. Printed Urdu data is the root cause
of problem. So for the rapid progress of Urdu language we need an
OCR systems, which can help us to make Urdu data available for the
common person. Research has been carried out for years to automata
Arabic and Urdu script. But the biggest hurdle in the development of
Urdu OCR is the challenge to recognize Nastalique Script which is
taken as standard for writing Urdu language. Nastalique script is
written diagonally with no fixed baseline which makes the script
somewhat complex. Overlap is present not only in characters but in
the ligatures as well. This paper proposes a method which allows
successful recognition of Nastalique Script.
Abstract: The resource-based view of the firm regards
knowledge as one of the most important organizational assets and a
key strategic resource that contributes unique value to organizations.
The acquisition, absorption and internalization of external
knowledge are central to an organization-s innovative capabilities.
This ability to evaluate, acquire and integrate new knowledge from
its environment is referred to as a firm-s absorptive capacity (AC).
This research in progress paper explores the link between interorganizational
Social Networks (SNs) and a firm-s Absorptive
Capacity (AC). Based on an in-depth literature survey of both
concepts, four propositions are proposed that explain the link
between AC and SNs. These propositions suggest that SNs are key
to a firm-s AC. A qualitative research method is proposed to test the
set of propositions in the next stage of this research.
Abstract: In this paper, the vessel inscribed trigonometry (VITM) for the vessel progression orientation (VPO) is proposed in the two-dimensional fundus image. The VPO is a major factor in the optic disc (OD) detection which is a basic process in the retina analysis. To measure the VPO, skeletons of vessel are used. First, the vessels are classified into three classes as vessel end, vessel branch and vessel stem. And the chain code maps of VS are generated. Next, two farthest neighborhoods of each point on VS are searched by the proposed angle restriction. Lastly, a gradient of the straight line between two farthest neighborhoods is estimated to measure the VPO. VITM is validated by comparing with manual results and 2D Gaussian templates. It is confirmed that VPO of the proposed mensuration is correct enough to detect OD from the results of experiment which applied VITM to detect OD in fundus images.
Abstract: Cloud Computing has recently emerged as a
compelling paradigm for managing and delivering services over the
internet. The rise of Cloud Computing is rapidly changing the
landscape of information technology, and ultimately turning the longheld
promise of utility computing into a reality. As the development
of Cloud Computing paradigm is speedily progressing, concepts, and
terminologies are becoming imprecise and ambiguous, as well as
different technologies are interfering. Thus, it becomes crucial to
clarify the key concepts and definitions. In this paper, we present the
anatomy of Cloud Computing, covering its essential concepts,
prominent characteristics, its affects, architectural design and key
technologies. We differentiate various service and deployment
models. Also, significant challenges and risks need are tackled in
order to guarantee the long-term success of Cloud Computing. The
aim of this paper is to provide a better understanding of the anatomy
of Cloud Computing and pave the way for further research in this
area.
Abstract: This paper considers inference under progressive type II censoring with a compound Rayleigh failure time distribution. The maximum likelihood (ML), and Bayes methods are used for estimating the unknown parameters as well as some lifetime parameters, namely reliability and hazard functions. We obtained Bayes estimators using the conjugate priors for two shape and scale parameters. When the two parameters are unknown, the closed-form expressions of the Bayes estimators cannot be obtained. We use Lindley.s approximation to compute the Bayes estimates. Another Bayes estimator has been obtained based on continuous-discrete joint prior for the unknown parameters. An example with the real data is discussed to illustrate the proposed method. Finally, we made comparisons between these estimators and the maximum likelihood estimators using a Monte Carlo simulation study.
Abstract: This study was designed to investigate the role of serum nitric oxide and sialic acid in the development of diabetic nephropathy as disease marker. Total 210 diabetic patients (age and sex matched) were selected followed by informed consent and divided into four groups (70 each) as I: control; II: diabetic; III: diabetic hypertensive; IV: diabetic nephropathy. The blood samples of all subjects were collected and analyzed for serum nitric oxide, sialic acid, fasting blood glucose, serum urea, creatinine, HbA1c and GFR. The BMI, systolic and diastolic blood pressures, blood glucose, HbA1c and serum sialic acid levels were high (p
Abstract: The aim of this paper is to present current and future
procedures in castings procurement. Differences in procurement are
highlighted. The supplier selection criteria used in practice is
compared to literature findings. Different trends related to supply
chains are presented and it is described how they are reflected in
reality to castings procurement. To fulfil the aim, interviews were
conducted in nine companies using castings. It was found that largest
casting users have the most subcontractor foundries and it is more
typical that they have multiple suppliers for the same parts. Currently
only two companies out of nine purchase castings outside Europe,
but the others are also progressing in the same direction. The main
reason is the need to lower purchasing costs. Another trend is that all
companies want to buy cast components or sub-assemblies instead of
raw castings from foundries. It was found that price is a main
supplier selection criterion. All companies use competitive bidding in
supplier selection.
Abstract: For the past thirty years the Malaysian economy has been said to contribute well to the progress of the nations. However, the intensification of global economy activity and the extensive use of Information Communication Technologies (ICTs) in recent years are challenging government-s effort to further develop Malaysian society. The competition posed by the low wage economies such as China and Vietnam have made the government realise the importance of engaging in high-skill and high technology industries. It is hoped this will be the basis of attracting more foreign direct investment (FDI) in order to help the country to compete in globalised world. Using Vision 2020 as it targeted vision, the government has decided to engage in the use of ICTs and introduce many policies pertaining to it. Mainly based on the secondary analysis approach, the findings show that policy pertaining to ICTs in Malaysia contributes to economic growth, but the consequences of this have resulted in greater division within society. Although some of the divisions such as gender and ethnicity are narrowing down, the gap in important areas such as regions and class differences is becoming wider. The widespread use of ICTs might contribute to the further establishment of democracy in Malaysia, but the increasing number of foreign entities such as FDI and foreign workers, cultural hybridisation and to some extent cultural domination are contributing to neocolonialism in Malaysia. This has obvious consequences for the government-s effort to create a Malaysian national identity. An important finding of this work is that there are contradictions within ICT policy between the effort to develop the economy and society.
Abstract: The various applications of VLSI circuits in highperformance
computing, telecommunications, and consumer
electronics has been expanding progressively, and at a very hasty
pace. This paper describes a new model for partitioning a circuit
using DBSCAN and fuzzy ARTMAP neural network. The first step
is concerned with feature extraction, where we had make use
DBSCAN algorithm. The second step is the classification and is
composed of a fuzzy ARTMAP neural network. The performance of
both approaches is compared using benchmark data provided by
MCNC standard cell placement benchmark netlists. Analysis of the
investigational results proved that the fuzzy ARTMAP with
DBSCAN model achieves greater performance then only fuzzy
ARTMAP in recognizing sub-circuits with lowest amount of
interconnections between them The recognition rate using fuzzy
ARTMAP with DBSCAN is 97.7% compared to only fuzzy
ARTMAP.
Abstract: An attempt was made to study of nitrogen
components response of corn (Zea mays L.) to drought stress. A farm
research was done in RCBD as split-plot with four replications in
Khorramabad, west Iran. Drought stress levels as irrigation regimes
after 75 (control), 100, and 120 (stress) mm cumulative evaporation
were in main plots, and four seed corn varieties include 500 (medium
maturity), 647, 700, and 704 (long maturity) were as subplots.
Soluble protein, nitrate and proline amino acid were measured in
shoot and root at flowering stage, and grain yield was measured in
harvesting stage. As the drought progressed, the amount of nitrate
and proline followed an increasing trend, but soluble protein
decreased in shoot and root. The highest amount of nitrate and
proline was observed in longer maturity varieties than shorter ones,
but decrease yield of long maturity varieties was higher than medium
maturity varieties in drought condition, because of long duration of
stress.
Abstract: The purpose of this paper was to study motivation
factors affecting job performance effectiveness. This paper drew
upon data collected from an Internal Audit Staffs of Internal Audit
Line of Head Office of Krung Thai Public Company Limited.
Statistics used included frequency, percentage, mean and standard
deviation, t-test, and one-way ANOVA test. The finding revealed that
the majority of the respondents were female of 46 years of age and
over, married and live together, hold a bachelor degree, with an
average monthly income over 70,001 Baht. The majority of
respondents had over 15 years of work experience. They generally
had high working motivation as well as high job performance
effectiveness.
The hypotheses testing disclosed that employees with different
working status had different level of job performance effectiveness at
a 0.01 level of significance. Working motivation factors had an effect
on job performance in the same direction with high level. Individual
working motivation included working completion, reorganization,
working progression, working characteristic, opportunity,
responsibility, management policy, supervision, relationship with
their superior, relationship with co-worker, working position,
working stability, safety, privacy, working conditions, and payment.
All of these factors related to job performance effectiveness in the
same direction with medium level.
Abstract: Nowadays, the pace of business change is such that,
increasingly, new functionality has to be realized and reliably
installed in a matter of days, or even hours. Consequently, more and
more business processes are prone to a continuous change. The
objective of the research in progress is to use the MAP model, in a
conceptual modeling method for flexible and adaptive business
process. This method can be used to capture the flexibility
dimensions of a business process; it takes inspiration from
modularity concept in the object oriented paradigm to establish a
hierarchical construction of the BP modeling. Its intent is to provide
a flexible modeling that allows companies to quickly adapt their
business processes.
Abstract: This paper considers the Zlin region in terms of the
demographic conditions of the region - in particular the residential
structure and the educational background of the inhabitants. The
paper also considers migration of the population within the Zlin
region. Migration is of importance in terms of conservation of the
working potential of the region.