Abstract: The blood ducts must be occluded to avoid loss of
blood from vessels in laparoscopic surgeries. This paper presents a
locking mechanism to be used in a ligation laparoscopic procedure
(LigLAP I), as an alternative solution for a stapling procedure.
Currently, stapling devices are being used to occlude vessels. Using
these devices may result in some problems, including injury of bile
duct, taking up a great deal of space behind the vessel, and bile leak.
In this new procedure, a two-layer suture occludes a vessel. A
locking mechanism is also required to hold the suture. Since there is
a limited space at the device tip, a Shape Memory Alloy (SMA)
actuator is used in this mechanism. Suitability for cleanroom
applications, small size, and silent performance are among the
advantages of SMA actuators in biomedical applications. An
experimental study is conducted to examine the function of the
locking mechanism. To set up the experiment, a prototype of a
locking mechanism is built using nitinol, which is a nickel-titanium
shape memory alloy. The locking mechanism successfully locks a
polymer suture for all runs of the experiment. In addition, the effects
of various surface materials on the applied pulling forces are studied.
Various materials are mounted at the mechanism tip to compare the
maximum pulling forces applied to the suture for each material. The
results show that the various surface materials on the device tip
provide large differences in the applied pulling forces.
Abstract: Carbon tetrachloride (CCl4) is a well-known
hepatotoxin and exposure to this chemical is known to induce
oxidative stress and causes liver injury by the formation of free
radicals. Flacourtia indica commonly known as 'Baichi' has been
reported as an effective remedy for the treatment of a variety of
diseases. The objective of this study was to investigate the
hepatoprotective activity of aqueous extract of leaves of Flacourtia
indica against CCl4 induced hepatotoxicity. Animals were pretreated
with the aqueous extract of Flacourtia indica (250 & 500 mg/kg
body weight) for one week and then challenged with CCl4 (1.5 ml/kg
bw) in olive oil (1:1, v/v) on 7th day. Serum marker enzymes (ALP,
AST, ALT, Total Protein & Total Bilirubin) and TBARS level
(Marker for oxidative stress) were estimated in all the study groups.
Alteration in the levels of biochemical markers of hepatic damage
like AST, ALT, ALP, Total Protein, Total Bilirubin and lipid
peroxides (TBARS) were tested in both CCl4 treated and extract
treated groups. CCl4 has enhanced the AST, ALT, ALP and the
Lipid peroxides (TBARS) in liver. Treatment of aqueous extract of
Flacourtia indica leaves (250 & 500 mg/kg) exhibited a significant
protective effect by altering the serum levels of AST, ALT, ALP,
Total Protein, Total Bilirubin and liver TBARS. These biochemical
observations were supported by histopathological study of liver
sections. From this preliminary study it has been concluded that the
aqueous extract of the leaves of Flacourtia indica protects liver
against oxidative damages and could be used as an effective protector
against CCl4 induced hepatic damage. Our findings suggested that
Flacourtia indica possessed good hepatoprotective activity
Abstract: The purpose of the study was to determine if, among
32 brain injured adults in community rehabilitation programs, there is
a statistically significant relationship between the degree of severity
of brain injury and these adults- level of self-esteem and stress. The
researcher hypothesized there would be a statistically significant
difference and a statistically significant relationship in self-esteem
and stress levels among and TBI adults. A Pearson product moment
correlational analysis was implemented and results found a
statistically significant relationship between self-esteem and stress
levels. Future recommendations were suggested upon completion of
research.
Abstract: For the last decade, statistics show traumatic brain
injury (TBI) is a growing concern in our legal system. In an effort to
obtain data regarding the influence of neuropsychological expert
witness testimony in a criminal case, this study tested three
hypotheses. H1: The majority of jurors will vote not guilty, due to
mild head injury. H2: The jurors will give more credence to the
testimony of the neuropsychologist rather than the psychiatrist. H3:
The jurors will be more lenient in their sentencing, given the
testimony of the neuropsychologist-s testimony. The criterion for
inclusion in the study as a participant is identical to those used for
inclusion in the eligibility for jury duty in the United States. A chisquared
test was performed to analyze the data for the three
hypotheses. The results supported all of the hypotheses; however
statistical significance was seen in H1 and H2 only.