Abstract: The urbanization phenomenon in Yogyakarta Special
Province, Indonesia, encouraged people move to the city for getting
jobs in the informal sectors. They live in some temporary houses in
the three main riverbanks: Gadjahwong, Code, and Winongo.
Triggered by its independent status they use it as the space for
accommodating domestic, social and economy activities because of
the non standardized room size of their houses, where are recognized
as the environmental hazards. This recognition makes the ambivalent
perception when was related to the twelfth point of the philosophy of
community development concept: the empowering individuals and
communities. Its spatial implication have actually described the
territory and the place making phenomena. By analyzing some data
collected the author-s fundamental research funded by The General
Directorate of Higher Education of Indonesia, this paper will discuss
how do the spatial implications of the occupants- behavior and the
numerous perceptions of those phenomena.
Abstract: Multidrug resistant organisms have been taunting the
medical world for the last few decades. Even with new antibiotics
developed, resistant strains have emerged soon after. With the
advancement of nanotechnology, we investigated colloidal silver
nanoparticles for its antimicrobial activity against Pseudomonas
aeruginosa. This organism is a multidrug resistant which contributes
to the high morbidity and mortality in immunocompromised patients.
Five multidrug resistant strains were used in this study. The
antimicrobial effect was studied using the disc diffusion and broth
dilution techniques. An inhibition zone of 11 mm was observed with
10 μg dose of the nanoparticles. The nanoparticles exhibited MIC of
50 μg/ml when added at the lag phase and the subinhibitory
concentration was measured as 100 μg/ml. The MIC50 value showed
to be 15 μg/ml. This study suggests that silver nanoparticles can be
further developed as an antimicrobial agent, hence decreasing the
burden of the multidrug resistance phenomena.
Abstract: Cognitive Science appeared about 40 years ago,
subsequent to the challenge of the Artificial Intelligence, as common
territory for several scientific disciplines such as: IT, mathematics,
psychology, neurology, philosophy, sociology, and linguistics. The
new born science was justified by the complexity of the problems
related to the human knowledge on one hand, and on the other by the
fact that none of the above mentioned sciences could explain alone
the mental phenomena. Based on the data supplied by the
experimental sciences such as psychology or neurology, models of
the human mind operation are built in the cognition science. These
models are implemented in computer programs and/or electronic
circuits (specific to the artificial intelligence) – cognitive systems –
whose competences and performances are compared to the human
ones, leading to the psychology and neurology data reinterpretation,
respectively to the construction of new models. During these
processes if psychology provides the experimental basis, philosophy
and mathematics provides the abstraction level utterly necessary for
the intermission of the mentioned sciences.
The ongoing general problematic of the cognitive approach
provides two important types of approach: the computational one,
starting from the idea that the mental phenomenon can be reduced to
1 and 0 type calculus operations, and the connection one that
considers the thinking products as being a result of the interaction
between all the composing (included) systems. In the field of
psychology measurements in the computational register use classical
inquiries and psychometrical tests, generally based on calculus
methods. Deeming things from both sides that are representing the
cognitive science, we can notice a gap in psychological product
measurement possibilities, regarded from the connectionist
perspective, that requires the unitary understanding of the quality –
quantity whole. In such approach measurement by calculus proves to
be inefficient. Our researches, deployed for longer than 20 years,
lead to the conclusion that measuring by forms properly fits to the
connectionism laws and principles.
Abstract: A systems approach model for prostate cancer in prostate duct, as a sub-system of the organism is developed. It is accomplished in two steps. First this research work starts with a nonlinear system of coupled Fokker-Plank equations which models continuous process of the system like motion of cells. Then extended to PDEs that include discontinuous processes like cell mutations, proliferation and deaths. The discontinuous processes is modeled by using intensity poisson processes. The model incorporates the features of the prostate duct. The system of PDEs spatial coordinate is along the proximal distal axis. Its parameters depend on features of the prostate duct. The movement of cells is biased towards distal region and mutations of prostate cancer cells is localized in the proximal region. Numerical solutions of the full system of equations are provided, and are exhibit traveling wave fronts phenomena. This motivates the use of the standard transformation to derive a canonically related system of ODEs for traveling wave solutions. The results obtained show persistence of prostate cancer by showing that the non-negative cone for the traveling wave system is time invariant. The traveling waves have a unique global attractor is proved also. Biologically, the global attractor verifies that evolution of prostate cancer stem cells exhibit the avascular tumor growth. These numerical solutions show that altering prostate stem cell movement or mutation of prostate cancer cells lead to avascular tumor. Conclusion with comments on clinical implications of the model is discussed.