Abstract: Background: The objectives of this study were to
assess patient’s knowledge of appropriate sublingual glyceryl
trinitrate (GTN) use as well as to investigate how patients commonly
store and carry their sublingual GTN tablets. Methodology: This was
a cross-sectional survey, using a validated researcher-administered
questionnaire. The study involved cardiac patients receiving
sublingual GTN attending the outpatient and inpatient departments of
Taiping Hospital, a non-academic public care hospital. The minimum
calculated sample size was 92, but 100 patients were conveniently
sampled. Respondents were interviewed on 3 areas, including
demographic data, knowledge and use of sublingual GTN. Eight
items were used to calculate each subject’s knowledge score and six
items were used to calculate use score. Results: Of the 96 patients
who consented to participate, majority (96.9%) were well aware of
the indication of sublingual GTN. With regards to the mechanism of
action of sublingual GTN, 73 (76%) patients did not know how the
medication works. Majority of the patients (66.7%) knew about the
proper storage of the tablet. In relation to the maximum number of
sublingual GTN tablets that can be taken during each angina episode,
36.5% did not know that up to 3 tablets of sublingual GTN can be
taken during each episode of angina. Fifty four (56.2%) patients were
not aware that they need to replace sublingual GTN every 8 weeks
after receiving the tablets. Majority (69.8%) of the patients
demonstrated lack of knowledge with regards to the use of sublingual
GTN as prevention of chest pain. Conclusion: Overall, patients’
knowledge regarding the self-administration of sublingual GTN is
still inadequate. The findings support the need for more frequent
reinforcement of patient education, especially in the areas of
preventive use, storage and drug stability.
Abstract: Children are more susceptible to medication errors
than adults. Medication administration process is the last stage in the
medication treatment process and most of the errors detected in this
stage. Little research has been undertaken about medication errors in
children in the Middle East countries. This study was aimed to
evaluate how the paediatric nurses adhere to the medication
administration policy and also to identify any medication preparation
and administration errors or any risk factors. An observational,
prospective study of medication administration process from when
the nurses preparing patient medication until administration stage
(May to August 2014) was conducted in Saudi Arabia. Twelve
paediatric nurses serving 90 paediatric patients were observed. 456
drug administered doses were evaluated. Adherence rate was variable
in 7 steps out of 16 steps. Patient allergy information, dose
calculation, drug expiry date were the steps in medication
administration with lowest adherence rates. 63 medication
preparation and administration errors were identified with error rate
13.8% of medication administrations. No potentially life-threating
errors were witnessed. Few logistic and administrative factors were
reported. The results showed that the medication administration
policy and procedure need an urgent revision to be more sensible for
nurses in practice. Nurses’ knowledge and skills regarding to the
medication administration process should be improved.
Abstract: Information and Communication Technologies (ICTs)
are pervasive nowadays, including in education where they are
expected to improve the performance of learners. However, the hope
placed in ICTs to find viable solutions to the problem of poor
academic performance in schools in the developing world has not yet
yielded the expected benefits. This problem serves as a motivation to
this study whose aim is to examine the perceptions of educators on
the advantages and disadvantages of e-learning. This aim will be
subdivided into two types of research objectives. Objectives on the
identification and design of theories and models will be achieved
using content analysis and literature review. However, the objective
on the empirical testing of such theories and models will be achieved
through the survey of educators from different schools in the
Pinetown District of the South African Kwazulu-Natal province.
SPSS is used to quantitatively analyse the data collected by the
questionnaire of this survey using descriptive statistics and Pearson
correlations after assessing the validity and the reliability of the data.
The main hypothesis driving this study is that there is a relationship
between the demographics of educators’ and their adherence to
learning theories on one side, and their perceptions on the advantages
and disadvantages of e-learning on the other side, as argued by
existing research; but this research views these learning theories
under three perspectives: educators’ adherence to self-regulated
learning, to constructivism, and to progressivism. This hypothesis
was fully confirmed by the empirical study except for the
demographic factor where teachers’ level of education was found to
be the only demographic factor affecting the perceptions of educators
on the advantages and disadvantages of e-learning.
Abstract: Second line antiretroviral therapy (ART) regimen is
used when patients fail their first line regimen. There are many
factors such as non-adherence, drug resistance as well as virological
and immunological failure that lead to second line highly active
antiretroviral therapy (HAART) regimen treatment failure. This study
was aimed at determining predictor factors to treatment failure with
second line HAART and analyzing median survival time.
An observational, retrospective study was conducted in Sungai
Buloh Hospital (HSB) to assess current status of HIV patients treated
with second line HAART regimen. Convenience sampling was used
and 104 patients were included based on the study’s inclusion and
exclusion criteria. Data was collected for six months i.e. from July
until December 2013. Data was then analysed using SPSS version 18.
Kaplan-Meier and Cox regression analyses were used to measure
median survival times and predictor factors for treatment failure.
The study population consisted mainly of male subjects, aged 30-
45 years, who were heterosexual, and had HIV infection for less than
6 years. The most common second line HAART regimen given was
lopinavir/ritonavir (LPV/r)-based combination. Kaplan-Meier
analysis showed that patients on LPV/r demonstrated longer median
survival times than patients on indinavir/ritonavir (IDV/r) based
combination (p
Abstract: Cognitive symptoms and behavioral symptoms may, in fact, overlap and be related to the level of the general cognitive function. We have measured the behavioral aspects of autism and its correlation to the cognitive ability in 30 children with ASD. We used a neuropsychological Battery CANTAB eclipse to evaluate the ASD children's cognitive ability. Individuals with ASD and challenging behaviors showed significant correlation between some cognitive abilities and Motor aspects. Based on these findings, we can conclude that the motor behavioral problems in autism affect specific cognitive abilities in ASDs such as comprehension, learning, reversal, acquisition, attention set shifting, and speed of reaction to one stimulus. Future researches should also focus on the relationship between motor stereotypes and other subtypes of repetitive behaviors, such as verbal stereotypes, ritual routine adherence, and the use of different types of CANTAB tests.
Abstract: This work details the generation of thin films of
structured zeolite catalysts (ZSM–5 and Y) onto the surface of a
metal substrate (FeCrAlloy) using in-situ hydrothermal synthesis. In
addition, the zeolite Y is post-synthetically modified by acidified
ammonium ion exchange to generate US-Y. Finally the catalytic
activity of the structured ZSM-5 catalyst films (Si/Al = 11, thickness
146 0m) and structured US–Y catalyst film (Si/Al = 8, thickness
230m) were compared with the pelleted powder form of ZSM–5 and
USY catalysts of similar Si/Al ratios.
The structured catalyst films have been characterised using a range
of techniques, including X-ray diffraction (XRD), Electron
microscopy (SEM), Energy Dispersive X–ray analysis (EDX) and
Thermogravimetric Analysis (TGA). The transition from oxide-onalloy
wires to hydrothermally synthesised uniformly zeolite coated
surfaces was followed using SEM and XRD. In addition, the
robustness of the prepared coating was confirmed by subjecting these
to thermal cycling (ambient to 550oC).
The cracking of n–heptane over the pellets and structured catalysts
for both ZSM–5 and Y zeolite showed very similar product
selectivities for similar amounts of catalyst with an apparent
activation energy of around 60 kJ mol-1. This paper demonstrates that
structured catalysts can be manufactured with excellent zeolite
adherence and when suitably activated/modified give comparable
cracking results to the pelleted powder forms. These structured
catalysts will improve temperature distribution in highly exothermic
and endothermic catalysed processes.
Abstract: Self-management is becoming a new emphasis for healthcare systems around the world. But there are many different problems with adoption of new health-related intervention systems. The situation is even more complicated for chronically ill patients with disabilities, illiteracy, and impairment in judgment in addition to their conditions, or having multiple co-morbidities. Providing online decision support to manage patient health and to provide better support for chronically ill patients is a new way of dealing with chronic disease management. In this study, the importance of mobile technology through an m-Health system that supports self-management interventions including the care provider, family and social support, education and training, decision support, recreation, and ongoing patient motivation to promote adherence and sustainability of the intervention are discussed. A proposed theoretical model for adoption and sustainability of system use is developed, based on UTAUT2 and IS Continuance of Use models, both of which have been pre-validated through longitudinal studies. The objective of this paper is to show the importance of using mobile technology in adoption and sustainability of use of an m-Health system which will result in commercially sustainable self-management support for chronically ill patients.
Abstract: This is a national community based project to evaluate effectiveness of HBV vaccination program in prevention of infection. HBV markers were tested in the sera of 3600 vaccinated children. Infected children were followed up for 1 year. Prevalence of HBV infection was 0.39 % (0.28% positive for anti-HBc, 0.03% positive for HBsAg and 0.08% positive for both). One year later, 50% of positive anti-HBc children turned negative with sustained positivity for positive HBsAg cases. HBV infection was significantly higher at age above 9 years (0.6%) compared to 0.2% at age 3-9 years and 0% at younger age (P
Abstract: Thousands of masters athletes participate
quadrennially in the World Masters Games (WMG), yet this cohort
of athletes remains proportionately under-investigated. Due to a
growing global obesity pandemic in context of benefits of physical
activity across the lifespan, the prevalence of obesity in this unique
population was of particular interest. Data gathered on a sub-sample
of 535 football code athletes, aged 31-72 yrs ( =47.4, s =±7.1),
competing at the Sydney World Masters Games (2009) demonstrated
a significantly (p
Abstract: An implant elicits a biological response in the
surrounding tissue which determines the acceptance and long-term
function of the implant. Dental implants have become one of the
main therapy methods in clinic after teeth lose. A successful implant
is in contact with bone and soft tissue represent by fibroblasts. In our
study we focused on the interaction between six different chemically
and physically modified titanium implants (Tis-MALP, Tis-O, Tis-
OA, Tis-OPAAE, Tis-OZ, Tis-OPAE) with alveolar fibroblasts as
well as with five type of microorganisms (S. epidermis, S.mutans, S.
gordonii, S. intermedius, C.albicans). The analysis of microorganism
adhesion was determined by CFU (colony forming unite) and biofilm
formation. The presence of α3β1 and vinculin expression on alveolar
fibroblasts was demonstrated using phospho specific cell based
ELISA (PACE). Alveolar fibroblasts have the highest expression of
these proteins on Tis-OPAAE and Tis-OPAE. It corresponds with
results from bacterial adhesion and biofilm formation and it was
related to the lowest production of collagen I by alveolar fibroblasts
on Tis-OPAAE titanium disc.
Abstract: Thousands of masters athletes participate
quadrennially in the World Masters Games (WMG), yet this cohort
of athletes remains proportionately under-investigated. Due to a
growing global obesity pandemic in context of benefits of physical
activity across the lifespan, the BMI trends for this unique population
was of particular interest. The nexus between health, physical
activity and aging is complex and has raised much interest in recent
times due to the realization that a multifaceted approach is necessary
in order to counteract the obesity pandemic. By investigating age
based trends within a population adhering to competitive sport at
older ages, further insight might be gleaned to assist in understanding
one of many factors influencing this relationship.BMI was derived
using data gathered on a total of 6,071 masters athletes (51.9% male,
48.1% female) aged 25 to 91 years ( =51.5, s =±9.7), competing at
the Sydney World Masters Games (2009). Using linear and loess
regression it was demonstrated that the usual tendency for prevalence
of higher BMI increasing with age was reversed in the sample. This
trend in reversal was repeated for both male and female only sub-sets
of the sample participants, indicating the possibility of improved
prevalence of BMI with increasing age for both the sample as a
whole and these individual sub-groups.This evidence of improved
classification in one index of health (reduced BMI) for masters
athletes (when compared to the general population) implies there are
either improved levels of this index of health with aging due to
adherence to sport or possibly the reduced BMI is advantageous and
contributes to this cohort adhering (or being attracted) to masters
sport at older ages.
Abstract: In the present work, behavior of inoxydable steel as
reinforcement bar in composite concrete is being investigated. The
bar-concrete adherence in reinforced concrete (RC) beam is studied
and focus is made on the tension stiffening parameter. This study
highlighted an approach to observe this interaction behavior in
bending test instead of direct tension as per reported in many
references. The approach resembles actual loading condition of the
structural RC beam. The tension stiffening properties are then
applied to numerical finite element analysis (FEA) to verify their
correlation with laboratory results. Comparison with laboratory
shows a good correlation between the two. The experimental settings
is able to determine tension stiffening parameters in RC beam and
the modeling strategies made in ABAQUS can closely represent the
actual condition. Tension stiffening model used can represent the
interaction properties between inoxydable steel and concrete.
Abstract: The present paper considers the steady free
convection boundary layer flow of a viscoelastics fluid with constant
temperature in the presence of heat generation. The boundary layer
equations are an order higher than those for the Newtonian (viscous)
fluid and the adherence boundary conditions are insufficient to
determine the solution of these equations completely. The governing
boundary layer equations are first transformed into non-dimensional
form by using special dimensionless group. Computations are
performed numerically by using Keller-box method by augmenting
an extra boundary condition at infinity and the results are displayed
graphically to illustrate the influence of viscoelastic K, heat
generation γ , and Prandtl Number, Pr parameters on the velocity
and temperature profiles. The results of the surface shear stress in
terms of the local skin friction and the surface rate of heat transfer in
terms of the local Nusselt number for a selection of the heat
generation parameterγ (=0.0, 0.2, 0.5, 0.8, 1.0) are obtained and
presented in both tabular and graphical formats. Without effect of the
internal heat generation inside the fluid domain for which we take
γ = 0.0, the present numerical results show an excellent agreement
with previous publication.
Abstract: Whilst there is growing evidence that activity across the lifespan is beneficial for improved health, there are also many changes involved with the aging process and subsequently the potential for reduced indices of health. Data gathered on a subsample of 535 football code athletes, aged 31-72 yrs ( = 47.4, s = ±7.1), competing at the Sydney World Masters Games (2009) demonstrated a significantly (p < 0.001), reduced classification of obesity using Body Mass Index (BMI) when compared to the general Australian population. This evidence of improved classification in one index of health (BMI < 30) for master athletes (when compared to the general population) implies there are either improved levels of this index of health due to adherence to sport or possibly the reduced BMI is advantageous and contributes to this cohort adhering (or being attracted) to masters sport. Demonstration of this proportionately under-investigated World Masters Games population having improved health over the general population is of particular interest.
Abstract: The present paper considers the steady free convection
boundary layer flow of a viscoelastic fluid on solid sphere with
Newtonian heating. The boundary layer equations are an order higher
than those for the Newtonian (viscous) fluid and the adherence
boundary conditions are insufficient to determine the solution of
these equations completely. Thus, the augmentation an extra
boundary condition is needed to perform the numerical
computational. The governing boundary layer equations are first
transformed into non-dimensional form by using special
dimensionless group and then solved by using an implicit finite
difference scheme. The results are displayed graphically to illustrate
the influence of viscoelastic K and Prandtl Number Pr parameters on
skin friction, heat transfer, velocity profiles and temperature profiles.
Present results are compared with the published papers and are found
to concur very well.
Abstract: A cross sectional survey design was used to collect
data from 370 diabetic patients. Two instruments were used in
obtaining data; in-depth interview guide and researchers- developed
questionnaire. Fisher's exact test was used to investigate association
between the identified factors and nonadherence. Factors identified
were: socio-demographic factors such as: gender, age, marital status,
educational level and occupation; psychosocial obstacles such as:
non-affordability of prescribed diet, frustration due to the restriction,
limited spousal support, feelings of deprivation, feeling that
temptation is inevitable, difficulty in adhering in social gatherings
and difficulty in revealing to host that one is diabetic; health care
providers obstacles were: poor attitude of health workers, irregular
diabetes education in clinics , limited number of nutrition education
sessions/ inability of the patients to estimate the desired quantity of
food, no reminder post cards or phone calls about upcoming patient
appointments and delayed start of appointment / time wasting in
clinics.
Abstract: Whilst there is growing evidence that activity
across the lifespan is beneficial for improved health, there are
also many changes involved with the aging process and
subsequently the potential for reduced indices of health. The
nexus between health, physical activity and aging is complex
and has raised much interest in recent times due to the
realization that a multifaceted approached is necessary in
order to counteract a growing obesity epidemic. By
investigating age based trends within a population adhering to
competitive sport at older ages, further insight might be
gleaned to assist in understanding one of many factors
influencing this relationship.
BMI was derived using data gathered on a total of 6,071
masters athletes (51.9% male, 48.1% female) aged 25 to 91
years ( =51.5, s =±9.7), competing at the Sydney World
Masters Games (2009). Using linear and loess regression it
was demonstrated that the usual tendency for prevalence of
higher BMI increasing with age was reversed in the sample.
This trend in reversal was repeated for both male and female
only sub-sets of the sample participants, indicating the
possibility of improved prevalence of BMI with increasing
age for both the sample as a whole and these individual subgroups.
This evidence of improved classification in one index of
health (reduced BMI) for masters athletes (when compared to
the general population) implies there are either improved
levels of this index of health with aging due to adherence to
sport or possibly the reduced BMI is advantageous and
contributes to this cohort adhering (or being attracted) to
masters sport at older ages. Demonstration of this
proportionately under-investigated World Masters Games
population having an improved relationship between BMI and
increasing age over the general population is of particular
interest in the context of the measures being taken globally to
curb an obesity epidemic.