Abstract: Female breast cancer is the second in frequency after cervical cancer. Surgery is the most common treatment for breast cancer, followed by chemotherapy as a treatment of choice. Although effective, it causes serious side effects. Controlled-release drug delivery is an alternative method to improve the efficacy and safety of the treatment. It can release the dosage of drug between the minimum effect concentration (MEC) and minimum toxic concentration (MTC) within tumor tissue and reduce the damage of normal tissue and the side effect. Because an in vivo experiment of this system can be time-consuming and labor-intensive, a mathematical model is desired to study the effects of important parameters before the experiments are performed. Here, we describe a 3D mathematical model to predict the release of doxorubicin from pluronic gel to treat human breast cancer. This model can, ultimately, be used to effectively design the in vivo experiments.
Abstract: The task of face recognition has been actively
researched in recent years. This paper provides an up-to-date review of major human face recognition research. We first present an
overview of face recognition and its applications. Then, a literature review of the most recent face recognition techniques is presented.
Description and limitations of face databases which are used to test
the performance of these face recognition algorithms are given. A
brief summary of the face recognition vendor test (FRVT) 2002, a
large scale evaluation of automatic face recognition technology, and
its conclusions are also given. Finally, we give a summary of the research results.
Abstract: A generalized unified power quality conditioner
(GUPQC) by using three single-phase three-level voltage source
converters (VSCs) connected back-to-back through a common dc
link is proposed in this paper as a new custom power device for a
three-feeder distribution system. One of the converters is connected
in shunt with one feeder for mitigation of current harmonics and
reactive power compensation, while the other two VSCs are
connected in series with the other two feeders to maintain the load
voltage sinusoidal and at constant level. A new control scheme based
on synchronous reference frame is proposed for series converters.
The simulation analysis on compensation performance of GUPQC
based on PSCAD/EMTDC is reported.
Abstract: This paper presents a new algorithm for the channel estimation of the OFDM system based on a pilot signal for the new generation of high data rate communication systems. In orthogonal frequency division multiplexing (OFDM) systems over fast-varying fading channels, channel estimation and tracking is generally carried out by transmitting known pilot symbols in given positions of the frequency-time grid. In this paper, we propose to derive an improved algorithm based on the calculation of the mean and the variance of the adjacent pilot signals for a specific distribution of the pilot signals in the OFDM frequency-time grid then calculating of the entire unknown channel coefficients from the equation of the mean and the variance. Simulation results shows that the performance of the OFDM system increase as the length of the channel increase where the accuracy of the estimated channel will be increased using this low complexity algorithm, also the number of the pilot signal needed to be inserted in the OFDM signal will be reduced which lead to increase in the throughput of the signal over the OFDM system in compared with other type of the distribution such as Comb type and Block type channel estimation.
Abstract: The technological concepts such as wireless hospital
and portable cardiac telemetry system require the development of
physiological signal acquisition devices to be easily integrated into
the hospital database. In this paper we present the low cost, portable
wireless ECG acquisition hardware that transmits ECG signals to a
dedicated computer.The front end of the system obtains and
processes incoming signals, which are then transmitted via a
microcontroller and wireless Bluetooth module. A monitoring
purpose Bluetooth based end user application integrated with patient
database management module is developed for the computers. The
system will act as a continuous event recorder, which can be used to
follow up patients who have been resuscitatedfrom cardiac arrest,
ventricular tachycardia but also for diagnostic purposes for patients
with arrhythmia symptoms. In addition, cardiac information can be
saved into the patient-s database of the hospital.
Abstract: The standard investigational method for obstructive
sleep apnea syndrome (OSAS) diagnosis is polysomnography (PSG),
which consists of a simultaneous, usually overnight recording of
multiple electro-physiological signals related to sleep and
wakefulness. This is an expensive, encumbering and not a readily
repeated protocol, and therefore there is need for simpler and easily
implemented screening and detection techniques. Identification of
apnea/hypopnea events in the screening recordings is the key factor
for the diagnosis of OSAS. The analysis of a solely single-lead
electrocardiographic (ECG) signal for OSAS diagnosis, which may
be done with portable devices, at patient-s home, is the challenge of
the last years. A novel artificial neural network (ANN) based
approach for feature extraction and automatic identification of
respiratory events in ECG signals is presented in this paper. A
nonlinear principal component analysis (NLPCA) method was
considered for feature extraction and support vector machine for
classification/recognition. An alternative representation of the
respiratory events by means of Kohonen type neural network is
discussed. Our prospective study was based on OSAS patients of the
Clinical Hospital of Pneumology from Iaşi, Romania, males and
females, as well as on non-OSAS investigated human subjects. Our
computed analysis includes a learning phase based on cross signal
PSG annotation.
Abstract: Malting is usually carried out on intact barley seed,
while hull is still attached to it. In this study, oat grain with and
without hull was subjected to controlled germination to optimize its
enzymes activity, in such a way that lipase has the lowest and α-
amylase and proteinase the highest activities. Since pH has a great
impact on the activity of the enzymes, the pH of germination media
was set up to 3 to 8. In dehulled oats, lipase and α-amylase had the
lowest and highest activities in pHs 3 and 6, respectively whereas the
highest proteinase activity was evidenced at pH 7 and 4 in the oats
with and without hull respectively. While measurements indicated
that the effect of hull on the enzyme activities particularly in lipase
and amylase at each level of the pH are significantly different, the
best results were obtained in those samples in which their hull had
been removed. However, since the similar lipase activity in
germinated dehulled oat were recorded at the pHs 4 and 5, therefore
it was concluded that pH 5 in dehulled oat seed may provide the
optimum enzyme activity for all the enzymes.
Abstract: Poly (ethylene glycol) (PEG) molecules attached to surfaces have shown high potential as a protein repellent due to their flexibility and highly water solubility. A quartz crystal microbalance recording frequency and dissipation changes (QCM-D) has been used to study the adsorption from aqueous solutions, of lysozyme and α-lactalbumin proteins (the last with and without calcium) onto modified stainless steel surfaces. Surfaces were coated with poly(ethylene imine) (PEI) and silicate before grafting on PEG molecules. Protein adsorption was also performed on the bare stainless steel surface as a control. All adsorptions were conducted at 23°C and pH 7.2. The results showed that the presence of PEG molecules significantly reduced the adsorption of lysozyme and α- lactalbumin (with calcium) onto the stainless steel surface. By contrast, and unexpected, PEG molecules enhanced the adsorption of α-lactalbumin (without calcium). It is suggested that the PEG -α- lactalbumin hydrophobic interaction plays a dominant role which leads to protein aggregation at the surface for this latter observation. The findings also lead to the general conclusion that PEG molecules are not a universal protein repellent. PEG-on-PEI surfaces were better at inhibiting the adsorption of lysozyme and α-lactalbumin (with calcium) than with PEG-on-silicate surfaces.
Abstract: Uncertainties of a serial production line affect on the
production throughput. The uncertainties cannot be prevented in a
real production line. However the uncertain conditions can be
controlled by a robust prediction model. Thus, a hybrid model
including autoregressive integrated moving average (ARIMA) and
multiple polynomial regression, is proposed to model the nonlinear
relationship of production uncertainties with throughput. The
uncertainties under consideration of this study are demand, breaktime,
scrap, and lead-time. The nonlinear relationship of production
uncertainties with throughput are examined in the form of quadratic
and cubic regression models, where the adjusted R-squared for
quadratic and cubic regressions was 98.3% and 98.2%. We optimized
the multiple quadratic regression (MQR) by considering the time
series trend of the uncertainties using ARIMA model. Finally the
hybrid model of ARIMA and MQR is formulated by better adjusted
R-squared, which is 98.9%.
Abstract: This paper deals with new concept of using compressed atmospheric air as a zero pollution power source for running motorbikes. The motorbike is equipped with an air turbine in place of an internal combustion engine, and transforms the energy of the compressed air into shaft work. The mathematical modeling and performance evaluation of a small capacity compressed air driven vaned type novel air turbine is presented in this paper. The effect of isobaric admission and adiabatic expansion of high pressure air for different rotor to casing diameter ratios with respect to different vane angles (number of vanes) have been considered and analyzed. It is found that the shaft work output is optimum for some typical values of rotor / casing diameter ratios at a particular value of vane angle (no. of vanes). In this study, the maximum power is obtained as 4.5kW - 5.3kW (5.5-6.25 HP) when casing diameter is taken 100 mm, and rotor to casing diameter ratios are kept from 0.65 to 0.55. This value of output is sufficient to run motorbike.
Abstract: As more people from non-technical backgrounds
are becoming directly involved with large-scale ontology
development, the focal point of ontology research has shifted
from the more theoretical ontology issues to problems
associated with the actual use of ontologies in real-world,
large-scale collaborative applications. Recently the National
Science Foundation funded a large collaborative ontology
development project for which a new formal ontology model,
the Ontology Abstract Machine (OAM), was developed to
satisfy some unique functional and data representation
requirements. This paper introduces the OAM model and the
related algorithms that enable maintenance of an ontology that
supports node-based user access. The successful software
implementation of the OAM model and its subsequent
acceptance by a large research community proves its validity
and its real-world application value.
Abstract: In this study, aeroelastic response and performance
analyses have been conducted for a 5MW-Class composite wind
turbine blade model. Advanced coupled numerical method based on
computational fluid dynamics (CFD) and computational flexible
multi-body dynamics (CFMBD) has been developed in order to
investigate aeroelastic responses and performance characteristics of
the rotating composite blade. Reynolds-Averaged Navier-Stokes
(RANS) equations with k-ω SST turbulence model were solved for
unsteady flow problems on the rotating turbine blade model. Also,
structural analyses considering rotating effect have been conducted
using the general nonlinear finite element method. A fully implicit
time marching scheme based on the Newmark direct integration
method is applied to solve the coupled aeroelastic governing equations
of the 3D turbine blade for fluid-structure interaction (FSI) problems.
Detailed dynamic responses and instantaneous velocity contour on the
blade surfaces which considering flow-separation effects were
presented to show the multi-physical phenomenon of the huge rotating
wind- turbine blade model.
Abstract: Discovering new biological knowledge from the highthroughput biological data is a major challenge to bioinformatics today. To address this challenge, we developed a new approach for protein classification. Proteins that are evolutionarily- and thereby functionally- related are said to belong to the same classification. Identifying protein classification is of fundamental importance to document the diversity of the known protein universe. It also provides a means to determine the functional roles of newly discovered protein sequences. Our goal is to predict the functional classification of novel protein sequences based on a set of features extracted from each protein sequence. The proposed technique used datasets extracted from the Structural Classification of Proteins (SCOP) database. A set of spectral domain features based on Fast Fourier Transform (FFT) is used. The proposed classifier uses multilayer back propagation (MLBP) neural network for protein classification. The maximum classification accuracy is about 91% when applying the classifier to the full four levels of the SCOP database. However, it reaches a maximum of 96% when limiting the classification to the family level. The classification results reveal that spectral domain contains information that can be used for classification with high accuracy. In addition, the results emphasize that sequence similarity measures are of great importance especially at the family level.
Abstract: This research project is developed in order to study
managerial styles of modern Thai executives. The thorough
understanding will lead to continuous improvement and efficient
performance of Thai business organizations. Regarding managerial
skills, Thai executives focus heavily upon human skills. Also, the
negotiator roles are most emphasis in their management. In addition,
Thai executives pay most attention to the fundamental management
principles including Harmony and Unity of Direction of the
organizations. Moreover, the management techniques, consisting of
Team work and Career Planning are of their main concern. Finally,
Thai executives wish to enhance their firms- image and employees-
morale through conducting the ethical and socially responsible
activities. The major tactic deployed to stimulate employees- ethical
behaviors and mindset is Code of Ethics development.
Abstract: This is a cross-cultural study that determines South
African multinational enterprises (MNEs) entry strategies as they
invest in Africa. An integrated theoretical framework comprising the
transaction cost theory, Uppsala model, eclectic paradigm and the
distance framework was adopted. A sample of 40 South African
MNEs with 415 existing FDI entries in Africa was drawn. Using an
ordered logistic regression model, the impact of culture on the choice
of degree of control by South African MNEs in Africa was
determined. Cultural distance was one of significant factors that
influenced South African MNEs- choice of degree of control.
Furthermore, South African MNEs are risk averse in all countries in
Africa but minimize the risks differently across sectors. Service
sectors chooses to own their subsidiaries 100% and avoid dealing
with the locals while manufacturing, resources and construction
choose to have a local partner to share the risk.
Abstract: Renewed interest in propeller propulsion on aircraft
configurations combined with higher propeller loads lead to the question how the effects of the propulsion on model support disturbances
should be accounted for. In this paper, the determination of engine power effects on support interference of sting-mounted models is
demonstrated by a measurement on a four-engine turboprop aircraft.
CFD results on a more generic model are presented in order to clarify
the possible mechanism behind engine power effects on support
interference. The engine slipstream induces a local change in angle
of sideslip at the model sting thereby influencing the sting near-field and far-field effects. Whether or not the net result of these changes
in the disturbance pattern leads to a significant engine power effect depends on the configuration of the wind tunnel model and the test
setup.
Abstract: This paper presents a multi-objective order allocation
planning problem with the consideration of various real-world
production features. A novel hybrid intelligent optimization model,
integrating a multi-objective memetic optimization process, a Monte
Carlo simulation technique and a heuristic pruning technique, is
proposed to handle this problem. Experiments based on industrial data
are conducted to validate the proposed model. Results show that (1)
the proposed model can effectively solve the investigated problem by
providing effective production decision-making solutions, which
outperformsan NSGA-II-based optimization process and an industrial
method.
Abstract: This paper presented two new efficient algorithms
for contour approximation. The proposed algorithm is compared
with Ramer (good quality), Triangle (faster) and Trapezoid (fastest)
in this work; which are briefly described. Cartesian co-ordinates of
an input contour are processed in such a manner that finally
contours is presented by a set of selected vertices of the edge of the
contour. In the paper the main idea of the analyzed procedures for
contour compression is performed. For comparison, the mean
square error and signal-to-noise ratio criterions are used.
Computational time of analyzed methods is estimated depending on
a number of numerical operations. Experimental results are
obtained both in terms of image quality, compression ratios, and
speed. The main advantages of the analyzed algorithm is small
numbers of the arithmetic operations compared to the existing
algorithms.
Abstract: In a liberalized electricity market, it is not surprising
that different customers require different power quality (PQ) levels at
different price. Power quality related to several power disturbances is
described by many parameters, so how to define a comprehensive
hierarchy evaluation system of power quality (PQCHES) has become
a concerned issue. In this paper, based on four electromagnetic
compatibility (EMC) levels, the numerical range of each power
disturbance is divided into five grades (Grade I –Grade V), and the
“barrel principle" of power quality is used for the assessment of
overall PQ performance with only one grade indicator. A case study
based on actual monitored data of PQ shows that the site PQ grade
indicates the electromagnetic environment level and also expresses the
characteristics of loads served by the site.
The shortest plank principle of PQ barrel is an incentive
mechanism, which can combine with the rewards/penalty mechanism
(RPM) of consumed energy “on quality demand", to stimulate utilities
to improve the overall PQ level and also stimulate end-user more
“smart" under the infrastructure of future SmartGrid..
Abstract: This paper proposes the method combining artificial
neural network (ANN) with particle swarm optimization (PSO) to
implement the maximum power point tracking (MPPT) by controlling
the rotor speed of the wind generator. First, the measurements of wind
speed, rotor speed of wind power generator and output power of wind
power generator are applied to train artificial neural network and to
estimate the wind speed. Second, the method mentioned above is
applied to estimate and control the optimal rotor speed of the wind
turbine so as to output the maximum power. Finally, the result reveals
that the control system discussed in this paper extracts the maximum
output power of wind generator within the short duration even in the
conditions of wind speed and load impedance variation.