Abstract: The concept of national security in Iran is a
permanently effective factor in acceptance or rejection of many
international obligations. These obligations had been defined
according to the type of legislation of Iran in many aspects.
Therefore, there are several treaties at international level which
requires Iran’s security to come in contact with obligations in these
treaties in a way that an obstacle to join to them and their passage in
parliament. This issue is a typical category which every country pays
attention to be accepted in treaties or to include their national
security in that treaties and also they can see the related treaties from
this perspective, but this issue that 'what is the concept of Iran’s
national security', and 'To what extent it is changed in recent years,
especially after Islamic Revolution' are important issues that can be
criticized. Thus, this study is trying to assess singed treaties from the
perspective of Iran’s national security according of the true meaning
of treaty and to investigate how the international treaties may be in
conflict with Iran’s national security.
Abstract: Quantitative analyses of whisker movements provide a
means to study functional recovery and regeneration of mouse facial
nerve after an injury. However, accurate tracking of the mouse whisker
movement is challenging. Most methods for whisker tracking require
manual intervention, e.g. fixing the head of the mouse during a study.
Here we describe a semi-automated image processing method, which
is applied to high-speed video recordings of free-moving mice to track
the whisker movements. We first track the head movement of a mouse
by delineating the lower head contour frame-by-frame that allows for
detection of the location and orientation of the head. Then, a region of
interest is identified for each frame; the subsequent application of a
mask and the Hough transform detects the selected whiskers on each
side of the head. Our approach is used to examine the functional
recovery of damaged facial nerves in mice over a course of 21 days.
Abstract: Purpose: The study aimed to assess the depressant or
antidepressant effects of several Nonsteroidal Anti-Inflammatory
Drugs (NSAIDs) in mice: the selective cyclooxygenase-2 (COX-2)
inhibitor meloxicam, and the non-selective COX-1 and COX-2
inhibitors lornoxicam, sodium metamizole, and ketorolac. The
current literature data regarding such effects of these agents are
scarce.
Materials and methods: The study was carried out on NMRI mice
weighing 20-35 g, kept in a standard laboratory environment. The
study was approved by the Ethics Committee of the University of
Medicine and Pharmacy „Carol Davila”, Bucharest. The study agents
were injected intraperitoneally, 10 mL/kg body weight (bw) 1 hour
before the assessment of the locomotor activity by cage testing (n=10
mice/ group) and 2 hours before the forced swimming tests (n=15).
The study agents were dissolved in normal saline (meloxicam,
sodium metamizole), ethanol 11.8% v/v in normal saline (ketorolac),
or water (lornoxicam), respectively. Negative and positive control
agents were also given (amitryptilline in the forced swimming test).
The cage floor used in the locomotor activity assessment was divided
into 20 equal 10 cm squares. The forced swimming test involved
partial immersion of the mice in cylinders (15/9cm height/diameter)
filled with water (10 cm depth at 28C), where they were left for 6
minutes. The cage endpoint used in the locomotor activity assessment
was the number of treaded squares. Four endpoints were used in the
forced swimming test (immobility latency for the entire 6 minutes,
and immobility, swimming, and climbing scores for the final 4
minutes of the swimming session), recorded by an observer that was
„blinded” to the experimental design. The statistical analysis used the
Levene test for variance homogeneity, ANOVA and post-hoc
analysis as appropriate, Tukey or Tamhane tests.
Results: No statistically significant increase or decrease in the
number of treaded squares was seen in the locomotor activity
assessment of any mice group. In the forced swimming test,
amitryptilline showed an antidepressant effect in each experiment, at
the 10 mg/kg bw dosage. Sodium metamizole was depressant at 100
mg/kg bw (increased the immobility score, p=0.049, Tamhane test),
but not in lower dosages as well (25 and 50 mg/kg bw). Ketorolac
showed an antidepressant effect at the intermediate dosage of 5
mg/kg bw, but not so in the dosages of 2.5 and 10 mg/kg bw,
respectively (increased the swimming score, p=0.012, Tamhane test).
Meloxicam and lornoxicam did not alter the forced swimming
endpoints at any dosage level.
Discussion: 1) Certain NSAIDs caused changes in the forced
swimming patterns without interfering with locomotion. 2) Sodium
metamizole showed a depressant effect, whereas ketorolac proved
antidepressant. Conclusion: NSAID-induced mood changes are not
class effects of these agents and apparently are independent of the
type of inhibited cyclooxygenase (COX-1 or COX-2).
Disclosure: This paper was co-financed from the European Social
Fund, through the Sectorial Operational Programme Human Resources Development 2007-2013, project number POSDRU /159
/1.5 /S /138907 "Excellence in scientific interdisciplinary research,
doctoral and postdoctoral, in the economic, social and medical fields
-EXCELIS", coordinator The Bucharest University of Economic
Studies.
Abstract: The aim of the current study was to develop and
validate a Response to Stressful Situations Scale (RSSS) for the
Portuguese population. This scale assesses the degree of stress
experienced in scenarios that can constitute positive, negative and
more neutral stressors, and also describes the physiological,
emotional and behavioral reactions to those events according to their
intensity. These scenarios include typical stressor scenarios relevant
to patients with schizophrenia, which are currently absent from most
scales, assessing specific risks that these stressors may bring on
subjects, which may prove useful in non-clinical and clinical
populations (i.e. Patients with mood or anxiety disorders,
schizophrenia). Results from Principal Components Analysis and
Confirmatory Factor Analysis of two adult samples from general
population allowed to confirm a three-factor model with good fit
indices: χ2 (144)= 370.211, p = 0.000; GFI = 0.928; CFI = 0.927; TLI =
0.914, RMSEA = 0.055, P(rmsea ≤0.005) = .096; PCFI = .781.
Further data analysis of the scale revealed that RSSS is an adequate
assessment tool of stress response in adults to be used in further
research and clinical settings, with good psychometric characteristics,
adequate divergent and convergent validity, good temporal stability
and high internal consistency.
Abstract: The polymer foil used for manufacturing of
laminated glass members behaves in a viscoelastic manner with
temperature dependance. This contribution aims at incorporating
the time/temperature-dependent behavior of interlayer to our earlier
elastic finite element model for laminated glass beams. The model
is based on a refined beam theory: each layer behaves according
to the finite-strain shear deformable formulation by Reissner and
the adjacent layers are connected via the Lagrange multipliers
ensuring the inter-layer compatibility of a laminated unit. The
time/temperature-dependent behavior of the interlayer is accounted
for by the generalized Maxwell model and by the time-temperature
superposition principle due to the Williams, Landel, and Ferry.
The resulting system is solved by the Newton method with
consistent linearization and the viscoelastic response is determined
incrementally by the exponential algorithm. By comparing the model
predictions against available experimental data, we demonstrate that
the proposed formulation is reliable and accurately reproduces the
behavior of the laminated glass units.
Abstract: One of the most famous techniques which affect the
efficiency of a production line is the assembly line balancing (ALB)
technique. This paper examines the balancing effect of a whole
production line of a real auto glass manufacturer in three steps. In the
first step, processing time of each activity in the workstations is
generated according to a practical approach. In the second step, the
whole production process is simulated and the bottleneck stations
have been identified, and finally in the third step, several
improvement scenarios are generated to optimize the system
throughput, and the best one is proposed. The main contribution of
the current research is the proposed framework which combines two
famous approaches including Assembly Line Balancing and
Optimization via Simulation technique (OvS). The results show that
the proposed framework could be applied in practical environments,
easily.
Abstract: Kidney cancer is the most lethal urological cancer
accounting for 3% of adult malignancies. VHL, a tumor-suppressor
gene, is best known to be associated with renal cell carcinoma
(RCC). The VHL functions as negative regulator of hypoxia inducible
factors. Recent sequencing efforts have identified several novel
frequent mutations of histone modifying and chromatin remodeling
genes in ccRCC (clear cell RCC) including PBRM1 and SETD2. The
PBRM1 gene encodes the BAF180 protein, which involved in
transcriptional activation and repression of selected genes. SETD2
encodes a histone methyltransferase, which may play a role in
suppressing tumor development. In this study, RNAs of 30 paired
tumor and normal samples that were grouped according to the types
of kidney cancer and clinical characteristics of patients, including
gender and average age were examined by RT-PCR, SSCP and
sequencing techniques. VHL, PBRM1 and SETD2 expressions were
relatively down-regulated. However, statistically no significance was
found (Wilcoxon signed rank test, p>0.05). Interestingly, no mutation
was observed on the contrary of previous studies. Understanding the
molecular mechanisms involved in the pathogenesis of RCC has
aided the development of molecular-targeted drugs for kidney cancer.
Further analysis is required to identify the responsible genes rather
than VHL, PBRM1 and SETD2 in kidney cancer.
Abstract: In Hungary, the society has changed a lot for the past
25 years, and these changes could be detected in educational
situations as well. The number and the intensity of conflicts have
been increased in most fields of life, as well as at schools. Teachers
have difficulties to be able to handle school conflicts. What is more,
the new net generation, generation Z has values and behavioural
patterns different from those of the previous one, which might
generate more serious conflicts at school, especially with teachers
who were mainly socialising in a traditional teacher – student
relationship.
In Hungary, the bill CCIV of 2011 declared the foundation of
Institutes of Teacher Training in higher education institutes. One of
the tasks of the Institutes is to survey the competences and needs of
teachers working in public education and to provide further trainings
and services for them according to their needs and requirements. This
job is supported by the Social Renewal Operative Programs 4.1.2.B.
The professors of a college carried out a questionnaire and surveyed
the needs and the requirements of teachers working in the region.
Based on the results, the professors of the Institute of Teacher
Training decided to meet the requirements of teachers and to launch
short teacher further training courses in spring 2015. One of the
courses is going to focus on school conflict management through
mediation.
The aim of the pilot course is to provide conflict management
techniques for teachers and to present different mediation techniques
to them. The theoretical part of the course (5 hours) will enable
participants to understand the main points and the advantages of
mediation, while the practical part (10 hours) will involve teachers in
role plays to learn how to cope with conflict situations applying
mediation. We hope if conflicts could be reduced, it would influence
school atmosphere in a positive way and the teaching – learning
process could be more successful and effective.
Abstract: The relationship between the state and the religion is
different based on the fact that how powerful is the religion faith in a
state and of the influences that affected the views of the constitution
drafters according to the constitutional system they were based to
draft their constitution. This paper aims at providing, through a
comparative methodology, how it is regulated by the constitution the
relationship between the state and the religion. The object of this
study are the constitutions of Italy as a nation with catholic religious
tradition, Greece as a nation with orthodox religion tradition, and
Turkey as a nation which represents Muslim religion, while Albania
as a nation known for its religious plurality. In particular, the analysis
will be focused on the secular or religious principle provided in the
constitution of each respective state. This comparative overview
intends to discern which of the states analyzed is more tolerant and
fully respects the freedom of religion. It results that most of the states
subject of this study, despite their religious tradition have chosen the
secular principle in their constitutions, but the religious freedom is
differently guaranteed.
Abstract: The aim of this exploratory research is to understand
further how organisations can evaluate their activities, which
generate knowledge creation, to meet changing stakeholder
expectations. A Scale of Knowledge (SoK) Framework is proposed
which links knowledge management and organisational activities to
changing stakeholder expectations. The framework was informed by
the knowledge management literature, as well as empirical work
conducted via a single case study of a multi-site hospital organisation
in Saudi Arabia. Eight in-depth semi-structured interviews were
conducted with managers from across the organisation regarding
current and future stakeholder expectations, organisational
strategy/activities and knowledge management. Data were analysed
using thematic analysis and a hierarchical value map technique to
identify activities that can produce further knowledge and
consequently impact on how stakeholder expectations are met.
The SoK Framework developed may be useful to practitioners as
an analytical aid to determine if current organisational activities
produce organisational knowledge which helps them meet
(increasingly higher levels of) stakeholder expectations. The
limitations of the research and avenues for future development of the
proposed framework are discussed.
Abstract: The development of adaptive user interfaces (UI)
presents for a long time an important research area in which
researcher attempt to call upon the full resources and skills of several
disciplines, The adaptive UI community holds a thorough knowledge
regarding the adaptation of UIs with users and with contexts of use.
Several solutions, models, formalisms, techniques and mechanisms
were proposed to develop adaptive UI. In this paper, we propose an
approach based on the fuzzy set theory for modeling the concept of
the appropriateness of different solutions of UI adaptation with
different situations for which interactive systems have to adapt their
UIs.
Abstract: OPEN_EmoRec_II is an open multimodal corpus with
experimentally induced emotions. In the first half of the experiment,
emotions were induced with standardized picture material and in the
second half during a human-computer interaction (HCI), realized
with a wizard-of-oz design. The induced emotions are based on the
dimensional theory of emotions (valence, arousal and dominance).
These emotional sequences - recorded with multimodal data (facial
reactions, speech, audio and physiological reactions) during a
naturalistic-like HCI-environment one can improve classification
methods on a multimodal level.
This database is the result of an HCI-experiment, for which 30
subjects in total agreed to a publication of their data including the
video material for research purposes*. The now available open
corpus contains sensory signal of: video, audio, physiology (SCL,
respiration, BVP, EMG Corrugator supercilii, EMG Zygomaticus
Major) and facial reactions annotations.
Abstract: OPEN_EmoRec_II is an open multimodal corpus with
experimentally induced emotions. In the first half of the experiment,
emotions were induced with standardized picture material and in the
second half during a human-computer interaction (HCI), realized
with a wizard-of-oz design. The induced emotions are based on the
dimensional theory of emotions (valence, arousal and dominance).
These emotional sequences - recorded with multimodal data (facial
reactions, speech, audio and physiological reactions) during a
naturalistic-like HCI-environment one can improve classification
methods on a multimodal level.
This database is the result of an HCI-experiment, for which 30
subjects in total agreed to a publication of their data including the
video material for research purposes*. The now available open
corpus contains sensory signal of: video, audio, physiology (SCL,
respiration, BVP, EMG Corrugator supercilii, EMG Zygomaticus
Major) and facial reactions annotations.
Abstract: Mangosteen (Garcinia mangostana) pericarp is
considered as agricultural waste and not fully utilized in food
products. It is widely reported that mangosteen pericarp contains high
antioxidant properties. The objective of this study is to develop novel
yellow alkaline noodle (YAN) substituted with different levels of
mangosteen pericarp powder (MPP). YAN formulation was
substituted with different levels of MPP (0%, 5%, 10% and 15%).
The effect on nutritional and antioxidant properties was evaluated.
Higher substitution levels of MPP resulted in significant increase
(p
Abstract: Design concepts of real-time embedded system can be
realized initially by introducing novel design approaches. In this
literature, model based design approach and in-the-loop testing were
employed early in the conceptual and preliminary phase to formulate
design requirements and perform quick real-time verification. The
design and analysis methodology includes simulation analysis, model
based testing, and in-the-loop testing. The design of conceptual driveby-
wire, or DBW, algorithm for electronic control unit, or ECU, was
presented to demonstrate the conceptual design process, analysis, and
functionality evaluation. The concepts of DBW ECU function can be
implemented in the vehicle system to improve electric vehicle, or EV,
conversion drivability. However, within a new development process,
conceptual ECU functions and parameters are needed to be evaluated.
As a result, the testing system was employed to support conceptual
DBW ECU functions evaluation. For the current setup, the system
components were consisted of actual DBW ECU hardware, electric
vehicle models, and control area network or CAN protocol. The
vehicle models and CAN bus interface were both implemented as
real-time applications where ECU and CAN protocol functionality
were verified according to the design requirements. The proposed
system could potentially benefit in performing rapid real-time
analysis of design parameters for conceptual system or software
algorithm development.
Abstract: Rehabilitation of dam components such as foundations, buttresses, spillways and overtopping protection require a wide range of construction and design methodologies. Geotechnical Engineering considerations play an important role in the design and construction of foundations of new dams. Much investigation is required to assess and evaluate the existing dams. The application of roller compacting concrete (RCC) has been accepted as a new method for constructing new dams or rehabilitating old ones. In the past 40 years there have been so many changes in the usage of RCC and now it is one of most satisfactory solutions of water and hydropower resource throughout the world. The considerations of rehabilitation and construction of dams might differ due to upstream reservoir and its influence on penetrating and dewatering of downstream, operations requirements and plant layout. One of the advantages of RCC is its rapid placement which allows the dam to be operated quickly. Unlike ordinary concrete it is a drier mix, and stiffs enough for compacting by vibratory rollers. This paper evaluates some different aspects of RCC and focuses on its preparation progress.
Abstract: This study presented to reduce earthquake damage and
emergency rehabilitation of critical structures such as schools, hightech
factories, and hospitals due to strong ground motions associated
with climate changes. Regarding recent trend, a strong earthquake
causes serious damage to critical structures and then the critical
structure might be influenced by sequence aftershocks (or tsunami)
due to fault plane adjustments. Therefore, in order to improve seismic
performance of critical structures, retrofitted or strengthening study
of the structures under aftershocks sequence after emergency
rehabilitation of the structures subjected to strong earthquakes is
widely carried out. Consequently, this study used composite material
for emergency rehabilitation of the structure rather than concrete and
steel materials because of high strength and stiffness, lightweight,
rapid manufacturing, and dynamic performance. Also, this study was
to develop or improve the seismic performance or seismic retrofit of
critical structures subjected to strong ground motions and earthquake
aftershocks, by utilizing GFRP-Corrugated Infill Panels (GCIP).
Abstract: ABC classification is widely used by managers for
inventory control. The classical ABC classification is based on Pareto
principle and according to the criterion of the annual use value only.
Single criterion classification is often insufficient for a closely
inventory control. Multi-criteria inventory classification models have
been proposed by researchers in order to consider other important
criteria. From these models, we will consider a specific model in
order to make a sensitive analysis on the composite score calculated
for each item. In fact, this score, based on a normalized average
between a good and a bad optimized index, can affect the ABC-item
classification. We will focus on items differently assigned to classes
and then propose a classification compromise.
Abstract: Behavioral aspects of experience such as will power
are rarely subjected to quantitative study owing to the numerous
complexities involved. Will is a phenomenon that has puzzled
humanity for a long time. It is a belief that will power of an individual
affects the success achieved by them in life. It is also thought that a
person endowed with great will power can overcome even the most
crippling setbacks in life while a person with a weak will cannot make
the most of life even the greatest assets. This study is an attempt
to subject the phenomena of will to the test of an artificial neural
network through a computational model. The claim being tested is
that will power of an individual largely determines success achieved
in life. It is proposed that data pertaining to success of individuals
be obtained from an experiment and the phenomenon of will be
incorporated into the model, through data generated recursively using
a relation between will and success characteristic to the model.
An artificial neural network trained using part of the data, could
subsequently be used to make predictions regarding data points in
the rest of the model. The procedure would be tried for different
models and the model where the networks predictions are found to
be in greatest agreement with the data would be selected; and used
for studying the relation between success and will.
Abstract: Every year, a considerable amount of money is being
invested on research, mainly in the form of funding allocated to
universities and research institutes. To better distribute the available
funds and to set the most proper R&D investment strategies for the
future, evaluation of the productivity of the funded researchers and
the impact of such funding is crucial. In this paper, using the data on
15 years of journal publications of the NSERC (Natural Sciences and
Engineering research Council of Canada) funded researchers and by
means of bibliometric analysis, the scientific development of the
funded researchers and their scientific collaboration patterns will be
investigated in the period of 1996-2010. According to the results it
seems that there is a positive relation between the average level of
funding and quantity and quality of the scientific output. In addition,
whenever funding allocated to the researchers has increased, the
number of co-authors per paper has also augmented. Hence, the
increase in the level of funding may enable researchers to get
involved in larger projects and/or scientific teams and increase their
scientific output respectively.