Abstract: The main cause of Alzheimer disease (AD) was
believed to be mainly due to the accumulation of free radicals owing
to oxidative stress (OS) in brain tissue. The mechanism of the
neurotoxicity of Aluminum chloride (AlCl3) induced AD in
hippocampus Albino wister rat brain tissue, the curative & the
protective effects of Lipidium sativum group (LS) water extract were
assessed after 8 weeks by attenuated total reflection spectroscopy
ATR-IR and histologically by light microscope. ATR-IR results
revealed that the membrane phospholipid undergo free radical
attacks, mediated by AlCl3, primary affects the polyunsaturated fatty
acids indicated by the increased of the olefinic -C=CH sub-band area
around 3012 cm-1 from the curve fitting analysis. The narrowing in
the half band width (HBW) of the sνCH2 sub-band around 2852 cm-1
due to Al intoxication indicates the presence of trans form fatty acids
rather than gauch rotomer. The degradation of hydrocarbon chain to
shorter chain length, increasing in membrane fluidity, disorder, and
decreasing in lipid polarity in AlCl3 group indicated by the detected
changes in certain calculated area ratios compared to the control.
Administration of LS was greatly improved these parameters
compared to the AlCl3 group. Al influences the Aβ aggregation and
plaque formation, which in turn interferes to and disrupts the
membrane structure. The results also showed a marked increase in
the β-parallel and antiparallel structure, that characterize the Aβ
formation in Al-induced AD hippocampal brain tissue, indicated by
the detected increase in both amide I sub-bands around 1674, 1692
cm-1. This drastic increase in Aβ formation was greatly reduced in the
curative and protective groups compared to the AlCl3 group and
approached nearly the control values. These results supported too by
the light microscope. AlCl3 group showed significant marked
degenerative changes in hippocampal neurons. Most cells appeared
small, shrieked and deformed. Interestingly, the administration of LS
in curative and protective groups markedly decreases the amount of
degenerated cells compared to the non-treated group. In addition, the
intensity of congo red stained cells was decreased. Hippocampal
neurons looked more/or less similar to those of control. This study showed a promising therapeutic effect of Lipidium
sativum group (LS) on AD rat model that seriously overcome the
signs of oxidative stress on membrane lipid and restore the protein
misfolding.
Abstract: Various nanomaterials can be used as a drug delivery
vehicles in nanomedicine, called nanocarriers. They can either be
organic or inorganic, synthetic or natural-based. Although synthetic
nanocarriers are easier to produce, they can often be toxic for the
organism and thus not suitable for use in treatment. From naturalbased
nanocarriers, the most commonly used are protein cages or
viral capsids. In this work, virus bacteriophage λ was used for
delivery of different cytotoxic drugs (cisplatin, carboplatin,
oxaliplatin and doxorubicin). Large quantities of phage λ were
obtained from phage λ-producing strain of E. coli cultivated in
medium with 0.2% maltose. After killing of E. coli with chloroform
and its removal by centrifugation, the phage was concentrated by
ultracentrifugation at 130 000×g and 4°C for 3 h. The encapsulation
of the drugs was performed by infusion method and four different
concentrations of the drugs were encapsulated (200; 100; 50; 25
μg·mL-1). Free drug molecules were removed by filtration. The
encapsulation was verified using the absorbance for doxorubicin and
atomic absorption spectrometry for platinum cytostatics. The amount
of encapsulated drug linearly increased with the increasing
concentration of applied drug with the determination coefficient
R2=0.989 for doxorubicin; R2=0.967 for cisplatin; R2=0.989 for
carboplatin and R2=0.996 for oxaliplatin. The overall encapsulation
efficiency was calculated as 50% for doxorubicin; 8% for cisplatin;
6% for carboplatin and 10% for oxaliplatin.
Abstract: This paper discusses the thematic structure of Yoruba
popular music of Southwest Nigeria. It examines the use of themes
and variations in early and contemporary Juju music. The work is an
outcome of a research developed by the author in his doctoral studies
at the University of Lagos, Nigeria, with the aim of analyzing the
thematic and motivic developments in Yoruba popular genres.
Observations, interviews, live recordings and CDs were used as
methods for eliciting information. Field recordings and CDs of
selected musical samples were also transcribed and notated. The
research established the prevalent use of string of themes by Juju
musicians as a compositional technique in moving from one musical
section to another, as they communicate the verbal messages in their
song. These themes consist of the popular ‘call and response’ form
found in most African music, analogous to the western ‘subject and
answer’ style of the fugue or sonata form, although without the tonic–
dominant relations. Due to the short and repetitive form of African
melodies and rhythms, a theme is restated as a variation, where its
rhythmic and melodic motifs are stylistically developed and repeated,
but still retaining its recognizable core musical structure. The
findings of this study showed that Juju musicians generally often
employ a thematic plan where new themes are used to arrange the
songs into sections, and each theme is developed into variations in
order to further expand the music, eliminate monotony, and create
musical aesthetics, serving as hallmark of its musical identity. The
study established the musical and extra-musical attributes of the
genre, while recommending further research towards analyzing the
various compositional techniques employed in African popular
genres.
Abstract: The effects of the contact ball-lens on the soda lime
glass in laser thermal cleavage with a cw Nd-YAG laser were
investigated in this study. A contact ball-lens was adopted to generate
a bending force on the crack formation of the soda-lime glass in the
laser cutting process. The Nd-YAG laser beam (wavelength of 1064
nm) was focused through the ball-lens and transmitted to the soda-lime
glass, which was coated with a carbon film on the surface with a
bending force from a ball-lens to generate a tensile stress state on the
surface cracking. The fracture was controlled by the contact ball-lens
and a straight cutting was tested to demonstrate the feasibility.
Experimental observations on the crack propagation from the leading
edge, main section and trailing edge of the glass sheet were compared
with various mechanical and thermal loadings. Further analyses on the
stress under various laser powers and contact ball loadings were made
to characterize the innovative technology. The results show that the distributions of the side crack at the
leading and trailing edges are mainly dependent on the boundary
condition, contact force, cutting speed and laser power. With the
increase of the mechanical and thermal loadings, the region of the side
cracks might be dramatically reduced with proper selection of the
geometrical constrains. Therefore the application of the contact
ball-lens is a possible way to control the fracture in laser cleavage with
improved cutting qualities.
Abstract: Fading noise degrades the performance of cellular
communication, most notably in femto- and pico-cells in 3G and 4G
systems. When the wireless channel consists of a small number of
scattering paths, the statistics of fading noise is not analytically
tractable and poses a serious challenge to developing closed
canonical forms that can be analysed and used in the design of
efficient and optimal receivers. In this context, noise is multiplicative
and is referred to as stochastically local fading. In many analytical
investigation of multiplicative noise, the exponential or Gamma
statistics are invoked. More recent advances by the author of this
paper utilized a Poisson modulated-weighted generalized Laguerre
polynomials with controlling parameters and uncorrelated noise
assumptions. In this paper, we investigate the statistics of multidiversity
stochastically local area fading channel when the channel
consists of randomly distributed Rayleigh and Rician scattering
centers with a coherent Nakagami-distributed line of sight component
and an underlying doubly stochastic Poisson process driven by a
lognormal intensity. These combined statistics form a unifying triply
stochastic filtered marked Poisson point process model.
Abstract: The aim of sustainable architecture is to design
buildings with the least adverse effects on the environment and
provide better conditions for people. What building forms make the
best use of land? This question was addressed in the late 1960s at the
center of Land Use and Built Form Studies in Cambridge. This led to
a number of influential papers which had a great influence on the
practice of urban design. This paper concentrates on the results of
sustainability caused by climatic conditions in Iranian traditional
architecture in hot-arid regions. As people spent a significant amount
of their time in houses, it was very important to have such houses to
fulfill their needs physically and spiritually as well as satisfying their
cultural and religious aspects of their lifestyles. In a vast country such
as Iran with different climatic zones, traditional builders have
presented series of logical solutions for human comfort. These
solutions have been able to response to the environmental problems
for a long period of time. As a result, by considering the experience
in traditional architecture of hot–arid climate in Iran, it is possible to
attain sustainable architecture.
Abstract: Intermediate cities which also called medium size
cities have an important role in the process of globalization. It is
argued that, in some cases this type of cities may be depopulated or in
otherwise may be transformed as the periphery of metropolitans, so
that the personal identity of the city and its local cultural heritage
could suffer from its neighbor metropolitan. Over the last decades,
the role of tourism in the development process and the cultural
heritage has increased. The impact of tourism on socioeconomic
growth makes motivation for the study of tourism development in
regional and urban planning process. There are evidences that
tourism has a positive impact in local development and makes
economic motivations for cultural heritage protection. In this study,
by considering the role of tourism in local development, especially by
its economic and socio-cultural impacts, it is tried to introduce a
strategy for tourism development through a method of urban planning
for intermediate cities called as Base plan. Damavand is an
intermediate city located in Tehran province, Iran with a high
potential in tourism by its local specific characteristic like social
structure, antiquities and natural attractions. It’s selected as a suitable
case study for intended strategy which is a combination of urban
planning and tourism development methods. Focusing on recognition
of the historical and cultural heritage of Damavand, in this paper
through “base plan methodology” a strategy of urban planning
toward tourism development is prepared in order to make tourism
development as a support for cultural heritage of this city.
Abstract: Background: Maintaining the correct body balance is
essential in the prevention of falls in the elderly, which is especially
important for women because of postmenopausal osteoporosis and
the serious consequences of falls. One of the exercise methods which
is very popular among adults, and which may affect body balance in
the positive way is the Pilates method. The aim of the study was to
evaluate the effect of regular Pilates exercises on the ability to
maintain body balance in static conditions in adult healthy women.
Material and methods: The study group consisted of 20 healthy
women attending Pilates twice a week for at least 1 year. The control
group consisted of 20 healthy women physically inactive. Women in
the age range from 35 to 50 years old without pain in musculoskeletal
system or other pain were only qualified to the groups. Body balance
was assessed using MatScan VersaTek platform with Sway Analysis
Module based on Matscan Clinical 6.7 software (Tekscan Inc.,
U.S.A). The balance was evaluated under the following conditions:
standing on both feet with eyes open, standing on both feet with eyes
closed, one-leg standing (separately on the right and left foot) with
eyes open. Each test lasted 30 seconds. The following parameters
were calculated: estimated size of the ellipse of 95% confidence, the
distance covered by the Center of Gravity (COG), the size of the
maximum shift in the sagittal and frontal planes and load distribution
between the left and right foot, as well as between rear- and forefoot.
Results: It was found that there is significant difference between the
groups in favor of the study group in the size of the confidence
ellipse and maximum shifts of COG in the sagittal plane during
standing on both feet, both with the eyes open and closed (p
Abstract: Globally, many women are still disadvantaged when it
comes to business opportunities. Entrepreneurship development
programs, specifically designed to assist women entrepreneurs, are
assisting in solving this problem to a certain extent. The purpose of
this study is to identify the factors that motivate females to start their
own business. Females, from three different groups (2013, 2014 and
2015), who were all enrolled in a short learning program specifically
designed for women in early start-up stage or intending to start a
business, were asked what motivated them to start a business. The
results indicated that, from all three groups, the majority of the
women wanted to start a business to be independent and have
freedom and to add towards a social goal. The results further
indicated that in general, women would enter into entrepreneurship
activity due to pull factors rather than push factors.
Abstract: A retrospective study conducted at Christian Medical
College (CMC) Teaching Hospital, Vellore, India on 14th August
2014 to assess the accuracy of clinically estimated foetal weight upon
labour admission. Estimating foetal weight is a crucial factor in
assessing maternal and foetal complications during and after labour.
Medical notes of ninety-eight postnatal women who fulfilled the
inclusion criteria were studied to evaluate the correlation between
their recorded Estimated Foetal Weight (EFW) on admission and
actual birth weight (ABW) of the newborn after delivery. Data
concerning maternal and foetal demographics was also noted.
Accuracy was determined by absolute percentage error and
proportion of estimates within 10% of ABW. Actual birth weights
ranged from 950-4080g. A strong positive correlation between EFW
and ABW (r=0.904) was noted. Term deliveries (≥40 weeks) in the
normal weight range (2500-4000g) had a 59.5% estimation accuracy
(n=74) compared to pre-term (4000g) were underestimated by 25% (n=3) and low birthweight
(LBW) babies were overestimated by 12.7% (n=9). Registrars who
estimated foetal weight were accurate in babies within normal weight
ranges. However, there needs to be an improvement in predicting
weight of macrosomic and LBW foetuses. We have suggested the use
of an amended version of the Johnson’s formula for the Indian
population for improvement and a need to re-audit once
implemented.
Abstract: Radio Frequency Identification (RFID) has become a
key technology in the emerging concept of Internet of Things (IoT).
Naturally, business applications would require the deployment of
various RFID systems developed by different vendors that use
different data formats and structures. This heterogeneity poses a
challenge in developing real-life IoT systems with RFID, as
integration is becoming very complex and challenging. Semantic
integration is a key approach to deal with this challenge. To do so,
ontology for RFID systems need to be developed in order to
annotated semantically RFID systems, and hence, facilitate their
integration. Accordingly, in this paper, we propose ontology for
RFID systems. The proposed ontology can be used to semantically
enrich RFID systems, and hence, improve their usage and reasoning.
Abstract: Large-scale machine tools for the manufacturing of
large work pieces, e.g. blades, casings or gears for wind turbines,
feature pose-dependent dynamic behavior. Small structural damping
coefficients lead to long decay times for structural vibrations that
have negative impacts on the production process. Typically, these
vibrations are handled by increasing the stiffness of the structure by
adding mass. This is counterproductive to the needs of sustainable
manufacturing as it leads to higher resource consumption both in
material and in energy. Recent research activities have led to higher
resource efficiency by radical mass reduction that is based on controlintegrated
active vibration avoidance and damping methods. These
control methods depend on information describing the dynamic
behavior of the controlled machine tools in order to tune the
avoidance or reduction method parameters according to the current
state of the machine. This paper presents the appearance, consequences and challenges
of the pose-dependent dynamic behavior of lightweight large-scale
machine tool structures in production. It starts with the theoretical
introduction of the challenges of lightweight machine tool structures
resulting from reduced stiffness. The statement of the pose-dependent
dynamic behavior is corroborated by the results of the experimental
modal analysis of a lightweight test structure. Afterwards, the
consequences of the pose-dependent dynamic behavior of lightweight
machine tool structures for the use of active control and vibration
reduction methods are explained. Based on the state of the art of
pose-dependent dynamic machine tool models and the modal
investigation of an FE-model of the lightweight test structure, the
criteria for a pose-dependent model for use in vibration reduction are
derived. The description of the approach for a general posedependent
model of the dynamic behavior of large lightweight
machine tools that provides the necessary input to the aforementioned
vibration avoidance and reduction methods to properly tackle
machine vibrations is the outlook of the paper.
Abstract: Polycyclic Aromatic Hydrocarbons (PAHs) are
formed mainly because of incomplete combustion of organic
materials during industrial, domestic activities or natural occurrence.
Their toxicity and contamination of terrestrial and aquatic ecosystem
have been established. However, with limited validity index, previous
research has focused on PAHs isomer pair ratios of variable
physicochemical properties in source identification. The objective of
this investigation was to determine the empirical validity of Pearson
Correlation Coefficient (PCC) and Cluster Analysis (CA) in PAHs
source identification along soil samples of different land uses.
Therefore, 16 PAHs grouped, as Endocrine Disruption Substances
(EDSs) were determined in 10 sample stations in top and sub soils
seasonally. PAHs was determined the use of Varian 300 gas
chromatograph interfaced with flame ionization detector. Instruments
and reagents used are of standard and chromatographic grades
respectively. PCC and CA results showed that the classification of
PAHs along pyrolitic and petrogenic organics used in source
signature is about the predominance PAHs in environmental matrix.
Therefore, the distribution of PAHs in the studied stations revealed
the presence of trace quantities of the vast majority of the sixteen
PAHs, which may ultimately inhabit the actual source signature
authentication. Therefore, factors to be considered when evaluating
possible sources of PAHs could be; type and extent of bacterial
metabolism, transformation products/substrates, and environmental
factors such as salinity, pH, oxygen concentration, nutrients, light
intensity, temperature, co-substrates, and environmental medium are
hereby recommended as factors to be considered when evaluating
possible sources of PAHs.
Abstract: Novel wind-lens turbine designs can augment power
output. Vacuum-Assisted Resin Transfer Molding (VARTM) is used
to form large and complex structures from a Carbon Fiber Reinforced
Polymer (CFRP) composite. Typically, wind-lens turbine structures
are fabricated in segments, and then bonded to form the final structure.
This paper introduces five new adhesive joints, divided into two
groups: one is constructed between dry carbon and CFRP fabrics, and
the other is constructed with two dry carbon fibers. All joints and
CFRP fabrics were made in our laboratory using VARTM
manufacturing techniques. Specimens were prepared for tensile testing
to measure joint performance. The results showed that the second
group of joints achieved a higher tensile strength than the first group.
On the other hand, the tensile fracture behavior of the two groups
showed the same pattern of crack originating near the joint ends
followed by crack propagation until fracture.
Abstract: Well logging records can help to answer many
questions from a wide range of special interested information and
basic petrophysical properties to formation evaluation of oil and gas
reservoirs. The accurate calculations of porosity in carbonate
reservoirs are the most challenging aspects of the well logging
analysis. Many equations have been developed over the years based
on known physical principles or on empirically derived relationships,
which are used to calculate porosity, estimate lithology, and water
saturation; however these parameters are calculated from well logs by
using modern technique in a current study. Nasiriya oil field is one of
the giant oilfields in the Middle East, and the formation under study
is the Mishrif carbonate formation which is the shallowest
hydrocarbon bearing zone in this oilfield. Neurolog software was
used to digitize the scanned copies of the available logs.
Environmental corrections had been made as per Schlumberger charts
2005, which supplied in the Interactive Petrophysics software. Three
saturation models have been used to calculate water saturation of
carbonate formations, which are simple Archie equation, Dual water
model, and Indonesia model. Results indicate that the Mishrif
formation consists mainly of limestone, some dolomite, and shale.
The porosity interpretation shows that the logging tools have a good
quality after making the environmental corrections. The average
formation water saturation for Mishrif formation is around 0.4-
0.6.This study is provided accurate behavior of petrophysical
properties with depth for this formation by using modern software.
Abstract: Non-linear dynamic time history analysis is
considered as the most advanced and comprehensive analytical
method for evaluating the seismic response and performance of
multi-degree-of-freedom building structures under the influence of
earthquake ground motions. However, effective and accurate
application of the method requires the implementation of advanced
hysteretic constitutive models of the various structural components
including masonry infill panels. Sophisticated computational research
tools that incorporate realistic hysteresis models for non-linear
dynamic time-history analysis are not popular among the professional
engineers as they are not only difficult to access but also complex and
time-consuming to use. In addition, commercial computer programs
for structural analysis and design that are acceptable to practicing
engineers do not generally integrate advanced hysteretic models
which can accurately simulate the hysteresis behavior of structural
elements with a realistic representation of strength degradation,
stiffness deterioration, energy dissipation and ‘pinching’ under cyclic
load reversals in the inelastic range of behavior. In this scenario,
push-over or non-linear static analysis methods have gained
significant popularity, as they can be employed to assess the seismic
performance of building structures while avoiding the complexities
and difficulties associated with non-linear dynamic time-history
analysis. “Push-over” or non-linear static analysis offers a practical
and efficient alternative to non-linear dynamic time-history analysis
for rationally evaluating the seismic demands. The present paper is
based on the analytical investigation of the effect of distribution of
masonry infill panels over the elevation of planar masonry infilled
reinforced concrete [R/C] frames on the seismic demands using the
capacity spectrum procedures implementing nonlinear static analysis
[pushover analysis] in conjunction with the response spectrum
concept. An important objective of the present study is to numerically
evaluate the adequacy of the capacity spectrum method using
pushover analysis for performance based design of masonry infilled
R/C frames for near-field earthquake ground motions.
Abstract: Polymorphism is one of the main pillars of objectoriented
paradigm. It induces hidden forms of class dependencies
which may impact software quality, resulting in higher cost factor for
comprehending, debugging, testing, and maintaining the software. In
this paper, a new cognitive complexity metric called Cognitive
Weighted Polymorphism Factor (CWPF) is proposed. Apart from the
software structural complexity, it includes the cognitive complexity
on the basis of type. The cognitive weights are calibrated based on 27
empirical studies with 120 persons. A case study and experimentation
of the new software metric shows positive results. Further, a
comparative study is made and the correlation test has proved that
CWPF complexity metric is a better, more comprehensive, and more
realistic indicator of the software complexity than Abreu’s
Polymorphism Factor (PF) complexity metric.
Abstract: This study aimed to 1) develop pre-service teachers’
leadership skills through camp-based learning, and 2) develop preservice
teachers’ teamwork skills through camp-based learning. An
applied research methodology was used. The target group was
derived from a purposive selection. It involved 32 fourth-year
students in Early Childhood Education Program enrolling a course
entitled Seminar in Early Childhood Education provided during
second semester of academic year 2013. The treatment was camp-based
learning activities which applied a PDCA process including
four stages: 1) plan, 2) do, 3) check, and 4) act. Research instruments
were a learning camp program, a camp-based learning management
plan, a 5-level assessment form for leadership skills and a 5-level
assessment form for assessing teamwork skills. Data were analyzed
using descriptive statistics. Results were: 1) pre-service teachers’
leadership skills yielded the before treatment average score at x= 3.4,
S.D.=0.6 2and the after-treatment average score at x 4.29 , S.D.=0.66
pre-service teachers’ teamwork skills yielded the before-treatment
average score at x=3.31, S.D.=0.60 and the after-treatment average
score at x=4.42, S.D.=0.66 Both differences were statistically
significant at the .05 level. Thus, the pre-service teachers’ leadership
and teamwork skills were significantly improved through the camp-based
learning approach.
Abstract: The contemporary battlefield creates a demand for
more costly and highly advanced munitions. Training personnel
responsible for operations as well as immediate execution of combat
tasks which engage real asset is unrealistic and economically not
feasible. Owing to a wide array of exploited simulators and various
types of imitators, it is possible to reduce the costs. One of the
effective elements of training, which can be applied in the training of
all service branches, is imitator of aerial targets. This research serves
as an introduction to the commencement of design analysis over a
real aerial target imitator. Within the project, the basic aerodynamic
calculations were made, which enabled to determine its geometry,
design layout, performance as well as mass balance of individual
components. The conducted calculations of the parameters of flight
characteristics come closer to the real performance of such
Unmanned Aerial Vehicles.
Abstract: This investigation is focused on using of Mon dance
in Pathum Thani Province’s tradition and has the following
objectives: 1) to study the background of Mon dance in Pathum
Thani Province; 2) to study Mon dance in Pathum Thani Province;
and 3) to study of using Mon dance in Pathum Thani province’s
tradition. This qualitative research was conducted in Pathum Thani
province (in the central of Thailand). Data was collected from
documentary study and field data by means of observation, interview,
and group discussion. Workshops were also held with a total of 100
attendees, comprised of 20 key informants, 40 casual informants and
40 general informants. Data was validated using the triangulation
technique and the findings are presented using the descriptive
analysis. The results of the study show that the historical background
of Mon dance in Pathum Thani Province initiated during the war
evacuation from Martaban (south of Burma) to settle down in Sam
Khok, Pathum Thani Province in Ayutthaya period to Rattanakosin.
The study found that Mon dance typically consists of 12-13 dancing
process. The melodies have 12-13 songs. Piphat Mon (Mon
traditional music ensemble) is used in the performance. Performers
are dressed in Mon traditional costumes. The performers are 6-12
women and depending on the employer’s demands. Length of the
performance varies from the duration of music orchestration. Rituals
and customs performed are paying homage to teachers before the
performance. The offerings are composed of flowers, incense sticks,
candles, money gifts which are well arranged on a tray with pedestal,
and also liquors, tobaccos and pure water for asking propitiousness.
For the use of Mon dance in Pathum Thani Province’s tradition, it is
found that the dance is commonly performed in the funeral
ceremonial tradition at present because the physical postures of the
performance are considered graceful and exquisite. In addition, as for
its value, it has long been believed since the ancient times that Mon
dance was a sacred thing considered as the dignity and glorification
especially for funeral ceremonies of priest or royal hierarchy classes.
However, Mon dance has continued to be used in the traditions
associated with Mon people activities in Pathum Thani Province for
instance customary welcome for honor guest and Songkran festival.