Abstract: Introduction: Sodium-glucose co-transporter-2 (SGLT2) inhibitors are a new class of oral anti-diabetic drugs with a unique mechanism of action. They are used to improve glycaemic control in adults with type 2 diabetes by enhancing urinary glucose excretion. In the UAE, there has been certainly an increased use of these medications. As with any new medication, there are safety considerations related to their use in patients with type two diabetes. A retrospective study was conducted at the three main centres of the Imperial College London Diabetes Centre. Methodology: All patients in electronic database (Diamond) from October 2014 to October 2017 were included with a minimum of six months usage of sodium glucose co-transporter inhibitors that comprise canagliflozin, dapagliflozin and empagliflozin. There were 15 paired sample biochemical and clinical correlations. The analysis was done at the start of the study, three months and six months apart. SPSS version 24 was used for this study. Conclusion: This study of sodium glucose co-transporter-2 inhibitors used showed significant reductions in weight, glycated haemoglobin A1C, systolic and diastolic blood pressures. As the case with systematic reviews, there were similar changes in liver enzymes, raised total cholesterol, low density lipopoptein and high density lipoprotein. There was slight improvement in estimated glomerular filtration rate too. Our analysis also showed that they increased in the incidence of urinary tract symptoms and incidence of urinary tract infections.
Abstract: Among the diverse types of pollutants produced by anthropogenic activities, metals represent a serious threat, due to their accumulation in ecosystems and their elevated toxicity. The mine tailings of abandoned mines contain high levels of metals such as arsenic (As), zinc (Zn), copper (Cu), and lead (Pb), which do not suffer any degradation process, they are accumulated in environment. Abandoned mine tailings potentially could contaminate rivers and aquifers representing a risk for human health due to their high metal content. In an attempt to remove the metals and thereby mitigate the environmental pollution, an environmentally friendly and economical method of bioremediation has been introduced. Bioleaching has been actively studied over the last several years, and it is one of the bioremediation solutions used to treat heavy metals contained in sewage sludge, sediment and contaminated soil. Acidithiobacillus thiooxidans, an extremely acidophilic, chemolithoautotrophic, gram-negative, rod shaped microorganism, which is typically related to Cu mining operations (bioleaching), has been well studied for industrial applications. The sulfuric acid produced plays a major role in bioleaching. Specifically, Acidithiobacillus thiooxidans strain DSM 26636 has been able to leach Al, Ni, V, Fe, Mg, Si, and Ni contained in slags from coal combustion wastes. The present study reports the ability of A. thiooxidans DSM 26636 for the bioleaching of metals contained in two different mine tailing samples (MT1 and MT2). It was observed that Al, Fe, and Mn were removed in 36.3±1.7, 191.2±1.6, and 4.5±0.2 mg/kg for MT1, and in 74.5±0.3, 208.3±0.5, and 20.9±0.1 for MT2. Besides, < 1.5 mg/kg of Au and Ru were also bioleached from MT1; in MT2, bioleaching of Zn was observed at 55.7±1.3 mg/kg, besides removal of < 1.5 mg/kg was observed for As, Ir, Li, and 0.6 for Os in this residue. These results show the potential of strain DSM 26636 for the bioleaching of metals that came from different mine tailings.
Abstract: This paper presents the results of an experimental investigation carried out to evaluate the effects of partial replacement of cement and fine aggregate with industrial waste by-products on concrete strength properties. The Grey Taguchi approach has been used to optimize the mix proportions for desired properties. In this research work, a ternary combination of industrial waste by-products has been used. The experiments have been designed using Taguchi's L9 orthogonal array with four factors having three levels each. The cement was partially replaced by ladle furnace slag (LFS), fly ash (FA) and copper slag (CS) at 10%, 25% and 40% level and fine aggregate (sand) was partially replaced with electric arc furnace slag (EAFS), iron slag (IS) and glass powder (GP) at 20%, 30% and 40% level. Three water to binder ratios, fixed at 0.40, 0.44 and 0.48, were used, and the curing age was fixed at 7, 28 and 90 days. Thus, a series of nine experiments was conducted on the specimens for water to binder ratios of 0.40, 0.44 and 0.48 at 7, 28 and 90 days of the water curing regime. It is evident from the investigations that Grey Taguchi approach for optimization helps in identifying the factors affecting the final outcomes, i.e. compressive strength and split tensile strength of concrete. For the materials and a range of parameters used in this research, the present study has established optimum mixes in terms of strength properties. The best possible levels of mix proportions were determined for maximization through compressive and splitting tensile strength. To verify the results, the optimal mix was produced and tested. The mixture results in higher compressive strength and split tensile strength than other mixes. The compressive strength and split tensile strength of optimal mixtures are also compared with the control concrete mixtures. The results show that compressive strength and split tensile strength of concrete made with partial replacement of cement and fine aggregate is more than control concrete at all ages and w/c ratios. Based on the overall observations, it can be recommended that industrial waste by-products in ternary combinations can effectively be utilized as partial replacements of cement and fine aggregates in all concrete applications.
Abstract: In the Giovanelli illusion, some collinear dots appear misaligned, when each dot lies within a circle and the circles are not collinear. In this illusion, the role of the frame of reference, determined by the circles, is considered a crucial factor. Three experiments were carried out to study the influence of directionality of the circles on the misalignment. The adjustment method was used. Participants changed the orthogonal position of each dot, from the left to the right of the sequence, until a collinear sequence of dots was achieved. The first experiment verified the illusory effect of the misalignment. In the second experiment, the influence of two different directionalities of the circles (-0.58° and +0.58°) on the misalignment was tested. The results show an over-normalization on the sequences of the dots. The third experiment tested the misalignment of the dots without any inclination of the sequence of circles (0°). Only a local illusory effect was found. These results demonstrate that the directionality of the circles, as a global factor, can increase the misalignment. The findings also indicate that directionality and the frame of reference are independent factors in explaining the Giovanelli illusion.
Abstract: This work describes a framework for teaching of global software engineering (GSE) in university undergraduate programs. This framework proposes a method of teaching that incorporates adequate techniques of software requirements elicitation and validated tools of communication, critical aspects to global software development scenarios. The use of proposed framework allows teachers to simulate small software development companies formed by Latin American students, which build information systems. Students from three Latin American universities played the roles of engineers by applying an iterative development of a requirements specification in a global software project. The proposed framework involves the use of a specific purpose Wiki for asynchronous communication between the participants of the process. It is also a practice to improve the quality of software requirements that are formulated by the students. The additional motivation of students to participate in these practices, in conjunction with peers from other countries, is a significant additional factor that positively contributes to the learning process. The framework promotes skills for communication, negotiation, and other complementary competencies that are useful for working on GSE scenarios.
Abstract: Due to many applications and problems in the fields of plasma physics, geophysics, and other many topics, the interaction between the strain field and the magnetic field has to be considered. Adomian introduced the decomposition method for solving linear and nonlinear functional equations. This method leads to accurate, computable, approximately convergent solutions of linear and nonlinear partial and ordinary differential equations even the equations with variable coefficients. This paper is dealing with a mathematical model of generalized thermoelasticity of a half-space conducting medium. A magnetic field with constant intensity acts normal to the bounding plane has been assumed. Adomian’s decomposition method has been used to solve the model when the bounding plane is taken to be traction free and thermally loaded by harmonic heating. The numerical results for the temperature increment, the stress, the strain, the displacement, the induced magnetic, and the electric fields have been represented in figures. The magnetic field, the relaxation time, and the angular thermal load have significant effects on all the studied fields.
Abstract: This paper discusses the implementation of the boundary element method (BEM) on an Excel spreadsheet and how it can be used in teaching vector calculus and simulation. There are two separate spreadheets, within which Laplace equation is solved by the BEM in two dimensions (LIBEM2) and axisymmetric three dimensions (LBEMA). The main algorithms are implemented in the associated programming language within Excel, Visual Basic for Applications (VBA). The BEM only requires a boundary mesh and hence it is a relatively accessible method. The BEM in the open spreadsheet environment is demonstrated as being useful as an aid to teaching and learning. The application of the BEM implemented on a spreadsheet for educational purposes in introductory vector calculus and simulation is explored. The development of assignment work is discussed, and sample results from student work are given. The spreadsheets were found to be useful tools in developing the students’ understanding of vector calculus and in simulating heat conduction.
Abstract: Worldwide and mainly in the European Union, many standards, regulations, models and systems exists for the evaluation and identification of stakeholders’ requirements of individual universities and higher education (HE) in general. All systems are targeting to measure or evaluate the Universities’ Quality Assurance Systems and the services offered to the recipients of HE, mainly the students. Numerous surveys were conducted in the past either by each university or by organized bodies to identify the students’ satisfaction or to evaluate to what extent these requirements are fulfilled. In this paper, the main results of an ongoing 6-year joint research will be presented very briefly. This research deals with an in depth investigation of student’s satisfaction, students personal requirements, a cup analysis among these two parameters and compares different universities. Through this research an attempt will be made to address four very important questions in higher education establishments (HEE): (1) Are there any common requirements, parameters, good practices or questions that apply to a large number of universities that will assure that students’ requirements are fulfilled? (2) Up to what extent the individual programs of HEE fulfil the requirements of the stakeholders? (3) Are there any similarities on specific programs among European HEE? (4) To what extent the knowledge acquired in a specific course program is utilized or used in a specific country? For the execution of the research an internationally accepted questionnaire(s) was used to evaluate up to what extent the students’ requirements and satisfaction were fulfilled in 2012 and five years later (2017). Samples of students and or universities were taken from many European Universities. The questionnaires used, the sampling method and methodology adopted, as well as the comparison tables and results will be very valuable to any university that is willing to follow the same route and methodology or compare the results with their own HHE. Apart from the unique methodology, valuable results are demonstrated from the four case studies. There is a great difference between the student’s expectations or importance from what they are getting from their universities (in all parameters they are getting less). When there is a crisis or budget cut in HEE there is a direct impact to students. There are many differences on subjects taught in European universities.
Abstract: Technology era drives people to use mobile phone to support their daily life activities. Technology development has a rapid phase which pushes the IT company to adjust any technology changes in order to fulfill customer’s satisfaction. As a result of that, many companies in the USA emerged from systematics software development approach to agile software development approach in developing systems and applications to develop many mobile phone applications in a short phase to fulfill user’s needs. As a systematic approach is considered as time consuming, costly, and too risky, agile software development has become a more popular approach to use for developing software including mobile applications. This paper reflects a short-term project to develop a diet tracker mobile application using agile software development that focused on applying scrum framework in the development process.
Abstract: Cryptocurrencies are getting increasingly popular, but very few of them can be conveniently used in daily mobile phone purchases. To solve this problem, we demonstrate how to build a functional prototype of a mobile cryptocurrency-based e-commerce application the communicates with Near-Field Communication (NFC) tags. Using the system, users are able to purchase physical items with an NFC tag that contains an e-commerce URL. The payment is done simply by touching the tag with a mobile device and accepting the payment. Our method is constructive: we describe the design and technologies used in the implementation and evaluate the security and performance of the solution. Our main finding is that the analysis and measurements show that our solution is feasible for e-commerce.
Abstract: In the course of recent decades, medical imaging has
been dominated by the use of costly film media for review and
archival of medical investigation, however due to developments in
networks technologies and common acceptance of a standard digital
imaging and communication in medicine (DICOM) another approach
in light of World Wide Web was produced. Web technologies
successfully used in telemedicine applications, the combination of
web technologies together with DICOM used to design a web-based
and open source DICOM viewer. The Web server allowance to
inquiry and recovery of images and the images viewed/manipulated
inside a Web browser without need for any preinstalling software.
The dynamic site page for medical images visualization and
processing created by using JavaScript and HTML5 advancements.
The XAMPP ‘apache server’ is used to create a local web server for
testing and deployment of the dynamic site. The web-based viewer
connected to multiples devices through local area network (LAN) to
distribute the images inside healthcare facilities. The system offers a
few focal points over ordinary picture archiving and communication
systems (PACS): easy to introduce, maintain and independently
platforms that allow images to display and manipulated efficiently,
the system also user-friendly and easy to integrate with an existing
system that have already been making use of web technologies. The
wavelet-based image compression technique on which 2-D discrete
wavelet transform used to decompose the image then wavelet
coefficients are transmitted by entropy encoding after threshold to
decrease transmission time, stockpiling cost and capacity. The
performance of compression was estimated by using images quality
metrics such as mean square error ‘MSE’, peak signal to noise ratio
‘PSNR’ and compression ratio ‘CR’ that achieved (83.86%) when
‘coif3’ wavelet filter is used.
Abstract: Eyes are considered to be the most sensitive and
important organ for human being. Thus, any eye disorder will affect
the patient in all aspects of life. Cataract is one of those eye disorders
that lead to blindness if not treated correctly and quickly. This paper
demonstrates a model for automatic detection, classification, and
grading of cataracts based on image processing techniques and
artificial intelligence. The proposed system is developed to ease the
cataract diagnosis process for both ophthalmologists and patients.
The wavelet transform combined with 2D Log Gabor Wavelet
transform was used as feature extraction techniques for a dataset of
120 eye images followed by a classification process that classified the
image set into three classes; normal, early, and advanced stage. A
comparison between the two used classifiers, the support vector
machine SVM and the artificial neural network ANN were done for
the same dataset of 120 eye images. It was concluded that SVM gave
better results than ANN. SVM success rate result was 96.8%
accuracy where ANN success rate result was 92.3% accuracy.
Abstract: Plant viruses can cause loss of yield and quality in a
lot of important crops. Symptoms of pathogens are variable
depending on the cultivars and virus strain. Selection of resistant
potato varieties would reduce the risk of virus transmission and
significant economic impact. Other way to avoid reduced harvest
yields is regular potato seed production sampling and testing for viral
infection. The aim of this study was to determine the occurrence and
distribution of viral diseases according potato cultivars for further
selection of virus-free material in Georgia. During the summer 2015-
2016, 5 potato cultivars (Sante, Laura, Jelly, Red Sonia, Anushka) at
5 different farms located in Akhalkalaki were tested for 6 different
potato viruses: Potato virus A (PVA), Potato virus M (PVM), Potato
virus S (PVS), Potato virus X (PVX), Potato virus Y (PVY) and
potato leaf roll virus (PLRV). A serological method, Double
Antibody Sandwich-Enzyme linked Immunosorbent Assay (DASELISA)
was used at the laboratory to analyze the results. The result
showed that PVY (21.4%) and PLRV (19.7%) virus presence in
collected samples was relatively high compared to others. Researched
potato cultivars except Jelly and Laura were infected by PVY with
different concentrations. PLRV was found only in three potato
cultivars (Sante, Jelly, Red Sonia) and PVM virus (3.12%) was
characterized with low prevalence. PVX, PVA and PVS virus
infection was not reported. It would be noted that 7.9% of samples
were containing PVY/PLRV mix infection. Based on the results it
can be concluded that PVY and PLRV infections are dominant in all
research cultivars. Therefore significant yield losses are expected.
Systematic, long-term control of potato viral infection, especially
seed-potatoes, must be regarded as the most important factor to
increase seed productivity.
Abstract: The quantum communication technology is an evolving
design which connects multiple quantum enabled devices to internet
for secret communication or sensitive information exchange. In
future, the number of these compact quantum enabled devices
will increase immensely making them an integral part of present
communication systems. Therefore, safety and security of such
devices is also a major concern for us. To ensure the customer
sensitive information will not be eavesdropped or deciphered, we
need a strong authentications and encryption mechanism. In this
paper, we propose a mutual authentication scheme between these
smart quantum devices and server based on the secure exchange of
information through quantum channel which gives better solutions
for symmetric key exchange issues. An important part of this
work is to propose a secure mutual authentication protocol over
the quantum channel. We show that our approach offers robust
authentication protocol and further our solution is lightweight,
scalable, cost-effective with optimized computational processing
overheads.
Abstract: Driven by the demand of intelligent monitoring in
rehabilitation centers or hospitals, a high accuracy real-time location
system based on UWB (ultra-wideband) technology was proposed.
The system measures precise location of a specific person, traces his
movement and visualizes his trajectory on the screen for doctors or
administrators. Therefore, doctors could view the position of the
patient at any time and find them immediately and exactly when
something emergent happens. In our design process, different
algorithms were discussed, and their errors were analyzed. In addition,
we discussed about a , simple but effective way of correcting the
antenna delay error, which turned out to be effective. By choosing the
best algorithm and correcting errors with corresponding methods, the
system attained a good accuracy. Experiments indicated that the
ranging error of the system is lower than 7 cm, the locating error is
lower than 20 cm, and the refresh rate exceeds 5 times per second. In
future works, by embedding the system in wearable IoT (Internet of
Things) devices, it could provide not only physical parameters, but
also the activity status of the patient, which would help doctors a lot in
performing healthcare.
Abstract: Flight Data Monitoring (FDM) program assists an
operator in aviation industries to identify, quantify, assess and
address operational safety risks, in order to improve safety of flight
operations. FDM is a powerful tool for an aircraft operator integrated
into the operator’s Safety Management System (SMS), allowing to
detect, confirm, and assess safety issues and to check the
effectiveness of corrective actions, associated with human errors.
This article proposes a model for safety risk assessment level of flight
data in a different aspect of event focus based on fuzzy set values. It
permits to evaluate the operational safety level from the point of view
of flight activities. The main advantages of this method are proposed
qualitative safety analysis of flight data. This research applies the
opinions of the aviation experts through a number of questionnaires
Related to flight data in four categories of occurrence that can take
place during an accident or an incident such as: Runway Excursions
(RE), Controlled Flight Into Terrain (CFIT), Mid-Air Collision
(MAC), Loss of Control in Flight (LOC-I). By weighting each one
(by F-TOPSIS) and applying it to the number of risks of the event,
the safety risk of each related events can be obtained.
Abstract: The remarkable growth and evolution in information
and communication technology (ICT) in the past few decades has
transformed modern society in almost every aspect of life. The
impact and application of ICT have been observed in almost all walks
of life including science, arts, business, health, management,
engineering, sports, and education. ICT in education is being used
extensively for student learning, creativity, interaction, and
knowledge sharing and as a valuable source of teaching instrument.
Apart from the student’s perspective, it plays a vital role for teacher
education, instructional methods and curriculum development. There
is a significant difference in growth of ICT enabled education in
developing countries compared to developed nations and according to
research, this gap is widening. ICT gradually infiltrate in almost
every aspect of life. It has a deep and profound impact on our social,
economic, health, environment, development, work, learning, and
education environments. ICT provides very effective and dominant
tools for information and knowledge processing. It is firmly believed
that the coming generation should be proficient and confident in the
use of ICT to cope with the existing international standards. This is
only possible if schools can provide basic ICT infrastructure to
students and to develop an ICT-integrated curriculum which covers
all aspects of learning and creativity in students. However, there is a
digital divide and steps must be taken to reduce this digital divide
considerably to have the profound impact of ICT in education all
around the globe. This study is based on theoretical approach and an
extensive literature review is being conducted to see the successful
implementations of ICT integration in education and to identify
technologies and models which have been used in education in
developed countries. This paper deals with the modern applications
of ICT in schools for both teachers and students to uplift the learning
and creativity amongst the students. A brief history of technology in
education is presented and discussed are some important ICT tools
for both student and teacher’s perspective. Basic ICT-based
infrastructure for academic institutions is presented. The overall
conclusion leads to the positive impact of ICT in education by
providing an interactive, collaborative and challenging environment
to students and teachers for knowledge sharing, learning and critical
thinking.
Abstract: Aerial and ground robots have various advantages of usage in different missions. Aerial robots can move quickly and get a different sight of view of the area, but those vehicles cannot carry heavy payloads. On the other hand, unmanned ground vehicles (UGVs) are slow moving vehicles, since those can carry heavier payloads than unmanned aerial vehicles (UAVs). In this context, we investigate the performances of various Similarity Metrics to provide a common map for Heterogeneous Robot Team (HRT) in complex environments. Within the usage of Lidar Odometry and Octree Mapping technique, the local 3D maps of the environment are gathered. In order to obtain a common map for HRT, informative theoretic similarity metrics are exploited. All types of these similarity metrics gave adequate as allowable simulation time and accurate results that can be used in different types of applications. For the heterogeneous multi robot team, those methods can be used to match different types of maps.
Abstract: This paper presents a prediction performance of
feedforward Multilayer Perceptron (MLP) and Echo State Networks
(ESN) trained with extended Kalman filter. Feedforward neural
networks and ESN are powerful neural networks which can track and
predict nonlinear signals. However, their tracking performance
depends on the specific signals or data sets, having the risk of
instability accompanied by large error. In this study we explore this
process by applying different network size and leaking rate for
prediction of nonlinear or chaotic signals in MLP neural networks.
Major problems of ESN training such as the problem of initialization
of the network and improvement in the prediction performance are
tackled. The influence of coefficient of activation function in the
hidden layer and other key parameters are investigated by simulation
results. Extended Kalman filter is employed in order to improve the
sequential and regulation learning rate of the feedforward neural
networks. This training approach has vital features in the training of
the network when signals have chaotic or non-stationary sequential
pattern. Minimization of the variance in each step of the computation
and hence smoothing of tracking were obtained by examining the
results, indicating satisfactory tracking characteristics for certain
conditions. In addition, simulation results confirmed satisfactory
performance of both of the two neural networks with modified
parameterization in tracking of the nonlinear signals.
Abstract: In this work, we present an efficient approach for
solving variable-order time-fractional partial differential equations,
which are based on Legendre and Laguerre polynomials. First, we
introduced the pseudo-operational matrices of integer and variable
fractional order of integration by use of some properties of
Riemann-Liouville fractional integral. Then, applied together with
collocation method and Legendre-Laguerre functions for solving
variable-order time-fractional partial differential equations. Also, an
estimation of the error is presented. At last, we investigate numerical
examples which arise in physics to demonstrate the accuracy of the
present method. In comparison results obtained by the present method
with the exact solution and the other methods reveals that the method
is very effective.