Abstract: Today, the Internet based communication has widen
the opportunity of event monitoring system in the medical field.
There is always a need of analyzing and designing secure and reliable
mobile communication between the hospital and biomedical
engineers mobile units. This study has been carried out to find
possible solution using SIP-based event notification for alerting the
technical staff about the Biomedical Device (BMD) status and
Patients treatment session. The Session Initiation Protocol (SIP) can
be used to create a medical event notification system. SIP can work
on a variety of devices. Its adoption as the protocol of choice for third
generation wireless networks allows for a robust and scalable
environment. One of the advantages of SIP is that it supports personal
mobility through the separation of user addressing and device
addressing. The solution for Telemed alert notification system is
based on SIP - Specific Event Notification. The aim of this project is
to extend mobility service to the hospital technicians who are using
Telemedicine system.
Abstract: This paper presents the results of the preliminary investigation of microwave (MW) irradiation pretreatments on the anaerobic digestion of food residues using biochemical methane potential (BMP) assays. Low solids systems with a total solids (TS) content ranging from 5.0-10.0% were analyzed. The inoculum to bulk mass of substrates to water ratio was 1:2:2 (mass basis). The experimental conditions for pretreatments were as follows: a control (no MW irradiation), two runs with MW irradiation for 15 and 30 minutes at 320 W, and another two runs with MW irradiation at 528 W for 30 and 60 minutes. The cumulative biogas production were 6.3 L and 8.7 L for 15min/320 W and 30min/320 W MW irradiation conditions, respectively, and 10.5 L and 11.4 L biogas for 30min/528 W and 60min/528 W, respectively, as compared to the control giving 5.8 L biogas. Both an increase in exposure time of irradiation and power of MW had increased the rate and yield of biogas. Singlefactor ANOVA tests (p
Abstract: NFκB activation plays a crucial role in anti-apoptotic responses in response to the apoptotic signaling during tumor necrosis factor (TNFa) stimulation in Multiple Myeloma (MM). Although several drugs have been found effective for the treatment of MM by mainly inhibiting NFκB pathway, there are no any quantitative or qualitative results of comparison assessment on inhibition effect between different single drugs or drug combinations. Computational modeling is becoming increasingly indispensable for applied biological research mainly because it can provide strong quantitative predicting power. In this study, a novel computational pathway modeling approach is employed to comparably assess the inhibition effects of specific single drugs and drug combinations on the NFκB pathway in MM, especially the prediction of synergistic drug combinations.
Abstract: The overall penumbra is usually defined as the
distance, p20–80, separating the 20% and 80% of the dose on the beam axis at the depth of interest. This overall penumbra accounts
also for the fact that some photons emitted by the distal parts of the source are only partially attenuated by the collimator. Medulloblastoma is the most common type of childhood brain tumor
and often spreads to the spine. Current guidelines call for surgery to remove as much of the tumor as possible, followed by radiation of the brain and spinal cord, and finally treatment with chemotherapy.
The purpose of this paper was to present results on an Uniformity of dose distribution in radiation fields surrounding the spine using film
dosimetry and comparison with 3D treatment planning software.
Abstract: Soil washing process with a surfactant solution is a potential technology for the rapid removal of hydrophobic organic compound (HOC) from soil. However, large amount of washed water would be produced during operation and this should be treated effectively by proper methods. The soil washed water for complex contaminated site with HOC and heavy metals might contain high amount of pollutants such as HOC and heavy metals as well as used surfactant. The heavy metals in the soil washed water have toxic effects on microbial activities thus these should be removed from the washed water before proceeding to a biological waste-water treatment system. Moreover, the used surfactant solutions are necessary to be recovered for reducing the soil washing operation cost. In order to simultaneously remove the heavy metals and HOC from soil-washed water, activated carbon (AC) was used in the present study. In an anionic-nonionic surfactant mixed solution, the Cd(II) and phenanthrene (PHE) were effectively removed by adsorption on activated carbon. The removal efficiency for Cd(II) was increased from 0.027 mmol-Cd/g-AC to 0.142 mmol-Cd/g-AC as the mole ratio of SDS increased in the presence of PHE. The adsorptive capacity of PHE was also increased according to the SDS mole ratio due to the decrement of molar solubilization ratios (MSR) for PHE in an anionic-nonionic surfactant mixture. The simultaneous adsorption of HOC and cationic heavy metals using activated carbon could be a useful method for surfactant recovery and the reduction of heavy metal toxicity in a surfactant-enhanced soil washing process.
Abstract: Migration in breast cancer cell wound healing assay
had been studied using image fractal dimension analysis. The
migration of MDA-MB-231 cells (highly motile) in a wound healing
assay was captured using time-lapse phase contrast video microscopy
and compared to MDA-MB-468 cell migration (moderately motile).
The Higuchi fractal method was used to compute the fractal
dimension of the image intensity fluctuation along a single pixel
width region parallel to the wound. The near-wound region fractal
dimension was found to decrease three times faster in the MDA-MB-
231 cells initially as compared to the less cancerous MDA-MB-468
cells. The inner region fractal dimension was found to be fairly
constant for both cell types in time and suggests a wound influence
range of about 15 cell layer. The box-counting fractal dimension
method was also used to study region of interest (ROI). The MDAMB-
468 ROI area fractal dimension was found to decrease
continuously up to 7 hours. The MDA-MB-231 ROI area fractal
dimension was found to increase and is consistent with the behavior
of a HGF-treated MDA-MB-231 wound healing assay posted in the
public domain. A fractal dimension based capacity index has been
formulated to quantify the invasiveness of the MDA-MB-231 cells in
the perpendicular-to-wound direction. Our results suggest that image
intensity fluctuation fractal dimension analysis can be used as a tool
to quantify cell migration in terms of cancer severity and treatment
responses.
Abstract: As days go by, we hear more and more about HIV,
Ebola, Bird Flu and other dreadful viruses which were unknown a
few decades ago. In both detecting and fighting viral diseases
ordinary methods have come across some basic and important
difficulties. Vaccination is by a sense introduction of the virus to the
immune system before the occurrence of the real case infection. It is
very successful against some viruses (e.g. Poliomyelitis), while
totally ineffective against some others (e.g. HIV or Hepatitis-C). On
the other hand, Anti-virus drugs are mostly some tools to control and
not to cure a viral disease. This could be a good motivation to try
alternative treatments. In this study, some key features of possible
physical-based alternative treatments for viral diseases are presented.
Electrification of body parts or fluids (especially blood) with micro
electric signals with adjusted current or frequency is also studied. The
main approach of this study is to find a suitable energy field, with
appropriate parameters that are able to kill or deactivate viruses. This
would be a lengthy, multi-disciplinary research which needs the
contribution of virology, physics, and signal processing experts. It
should be mentioned that all the claims made by alternative cures
researchers must be tested carefully and are not advisable at the time
being.
Abstract: Candida spp. are common and aggressive pathogens.
Because of the growing resistance of Candida spp. to current
antifungals, novel targets, found in Candida spp. but not in humans
or other flora, have to be identified. The alternative oxidase (AOX)
is one such possibility. This enzyme is insensitive to cyanide, but is
sensitive to compounds such as salicylhydroxamic acid (SHAM),
disulfiram and n-alkyl gallates. The growth Candida albicans was
inhibited by SHAM (Ki = 9-15 mM) and cyanide (Ki = 2-4 mM),
albeit to differing extents. The rate of O2 uptake was inhibited by
less than 10% by 25 mM SHAM and by about 90% by 250 μM
KCN. Although SHAM substantially inhibited the growth of C.
albicans, it is unlikely that the inhibition of AOX was the cause.
Salicylhydroxamic acid is used therapeutically in the treatment of
urinary tract infections and urolithiasis, but it also has some potential
in the treatment of C. albicans infection.
Abstract: The evaluation of non-conventional water resources
on seed germination and seedling growth performance at early
growth stages is still in progress especially in forage crops. This
study was designed to test the effect of four types of water qualities
(treated wastewater (TWW), industrial water (IW), grey water (GW),
and Distilled water (DW)) on germination and early seedling vigor of
Leucaena leucocephala. The results showed that the germination
was not significantly affected by the different water qualities. Seed
germination reached maximum after 17, 14, 14, and 21 days under
GW, IW, TWW, and DW treatments, respectively. The highest mean
of shoot length was scored under the GW treatment. And, the highest
mean of root length was scored under DW which was not significant
from GW treatment. The means of shoot fresh was the highest under
the TWW. The means of root fresh weight was not significantly
different from each other's under different treatments. The growth
performance was in progress with no mortality during 21 days of
growth. Thus, the best non-conventional water qualities alternatives
based on the cleanness, nutrients, and toxicity are the GW, TWW and
IW, respectively.
Abstract: Environmental awareness and depletion of the
petroleum resources are among vital factors that motivate a number
of researchers to explore the potential of reusing natural fiber as an
alternative composite material in industries such as packaging,
automotive and building constructions. Natural fibers are available in
abundance, low cost, lightweight polymer composite and most
importance its biodegradability features, which often called “ecofriendly"
materials. However, their applications are still limited due
to several factors like moisture absorption, poor wettability and large
scattering in mechanical properties. Among the main challenges on
natural fibers reinforced matrices composite is their inclination to
entangle and form fibers agglomerates during processing due to
fiber-fiber interaction. This tends to prevent better dispersion of the
fibers into the matrix, resulting in poor interfacial adhesion between
the hydrophobic matrix and the hydrophilic reinforced natural fiber.
Therefore, to overcome this challenge, fiber treatment process is one
common alternative that can be use to modify the fiber surface
topology by chemically, physically or mechanically technique.
Nevertheless, this paper attempt to focus on the effect of
mercerization treatment on mechanical properties enhancement of
natural fiber reinforced composite or so-called bio composite. It
specifically discussed on mercerization parameters, and natural fiber
reinforced composite mechanical properties enhancement.
Abstract: Recently, a growing interest has emerged on the
development of new and efficient energy sources, due to the inevitable extinction of the nonrenewable energy reserves. One of
these alternative sources which has a great potential and sustainability to meet up the energy demand is biomass energy. This
significant energy source can be utilized with various energy
conversion technologies, one of which is biomass gasification in
supercritical water.
Water, being the most important solvent in nature, has very important characteristics as a reaction solvent under supercritical
circumstances. At temperatures above its critical point (374.8oC and
22.1 MPa), water becomes more acidic and its diffusivity increases.
Working with water at high temperatures increases the thermal
reaction rate, which in consequence leads to a better dissolving of the
organic matters and a fast reaction with oxygen. Hence, supercritical water offers a control mechanism depending on solubility, excellent
transport properties based on its high diffusion ability and new reaction possibilities for hydrolysis or oxidation.
In this study the gasification of a real biomass, namely olive mill
wastewater (OMW), in supercritical water is investigated with the
use of Pt/Al2O3 and Ni/Al2O3 catalysts. OMW is a by-product
obtained during olive oil production, which has a complex nature
characterized by a high content of organic compounds and
polyphenols. These properties impose OMW a significant pollution
potential, but at the same time, the high content of organics makes
OMW a desirable biomass candidate for energy production.
All of the catalytic gasification experiments were made with five
different reaction temperatures (400, 450, 500, 550 and 600°C),
under a constant pressure of 25 MPa. For the experiments conducted
with Ni/Al2O3 catalyst, the effect of five reaction times (30, 60, 90,
120 and 150 s) was investigated. However, procuring that similar
gasification efficiencies could be obtained at shorter times, the experiments were made by using different reaction times (10, 15, 20,
25 and 30 s) for the case of Pt/Al2O3 catalyst. Through these experiments, the effects of temperature, time and catalyst type on the
gasification yields and treatment efficiencies were investigated.
Abstract: Carbon nanotubes (CNTs) are attractive because of
their excellent chemical durability mechanical strength and electrical
properties. Therefore there is interest in CNTs for not only electrical
and mechanical application, but also biological and medical
application.
In this study, the dispersion power of surfactant-treated multiwalled
carbon nanotubes (MWCNTs) and their effect on the antibacterial
activity were examined. Surfactant was used sodium
dodecyl-benzenesulfonate (SDBS). UV-vis absorbance and
transmission electron microscopy(TEM) were used to characterize the
dispersion of MWCNTs in the aqueous phase, showing that the
surfactant molecules had been adsorbed onto the MWCNTs surface.
The surfactant-treated MWCNTs exhibited antimicrobial activities
to streptococcus mutans. The optical density growth curves and viable
cell number determined by the plating method suggested that the
antimicrobial activity of surfactant-treated MWCNTs was both
concentration and treatment time-dependent.
Abstract: The experiment was performed to evaluate the effect
of GA3, 2,4-D on fruit growth and fruit quality of wax apple. The
experiment consisted of Red A, Monulla, Atu, Red B cultivars. GA3
and 2,4-D were applied at the small bud and petal fall stage.
Physiological, biochemical characters of fruit were recoded. The
result showed application of GA3, 2,4-D greatly response in
increasing fruit set for all treatment as compared to control. Fruit
weight, fruit size were increased at 10 ppm 2,4-D in ‘Red A’, ‘Red
B’, however it was also enhancing at 10 ppm GA3 in ‘Monulla’,
‘Atu’. For ‘Monulla’, ‘Atu’ fruit crack reduced by 10 ppm 2,4-D
application, but ‘Red B’, ‘Red A’ gave least fruit crack at 10 and 30
ppm GA3, respectively. ‘Monulla’, ‘Atu’ and ‘Red B’ resulted in
response well to 10 ppm GA3 on improving TSS, whereas
application of 30 ppm GA3 greatly enhancing TSS in ‘Red A’. For
‘Atu’ titratable acidity markedly reduced by 10 ppm GA3
application, but spraying with 30 ppm GA3 greatly response in
reducing titratable acidity in ‘Red A’, ‘Red B’ and ‘Monulla’. It was
concluded that GA3, 2,4-D can be an effective tool to enhancing fruit
set, fruit growth as well as improving fruit quality of wax apple.
Abstract: Prolonged immobilization leads to significant
weakness and atrophy of the skeletal muscle and can also impair the
recovery of muscle strength following injury. Therefore, it is
important to minimize the period under immobilization and accelerate
the return to normal activity. This study examined the effects of heat
treatment and rest-inserted exercise on the muscle activity of the lower
limb during knee flexion/extension. Twelve healthy subjects were
assigned to 4 groups that included: (1) heat treatment + rest-inserted
exercise; (2) heat + continuous exercise; (3) no heat + rest-inserted
exercise; and (4) no heat + continuous exercise. Heat treatment was
applied for 15 mins prior to exercise. Continuous exercise groups
performed knee flexion/extension at 0.5 Hz for 300 cycles without rest
whereas rest-inserted exercise groups performed the same exercise but
with 2 mins rest inserted every 60 cycles of continuous exercise.
Changes in the rectus femoris and hamstring muscle activities were
assessed at 0, 1, and 2 weeks of treatment by measuring the
electromyography signals of isokinetic maximum voluntary
contraction. Significant increases in both the rectus femoris and
hamstring muscles were observed after 2 weeks of treatment only
when both heat treatment and rest-inserted exercise were performed.
These results suggest that combination of various treatment techniques,
such as heat treatment and rest-inserted exercise, may expedite the
recovery of muscle strength following immobilization.
Abstract: A thin coating of hexamethyldisiloxane and subsequent O2-plasma treatment was performed on mirror-polished titanium in order to regulate the wide range of wettability including 106 and almost 0 degrees of contact angles. The adsorption behavior of
fibronectin and albumin in both individual and competitive mode,
and initial attachment of fibroblasts and osteoblasts were investigated.
Individually, fibronectin adsorption showed a biphasic inclination, whereas albumin showed greater adsorption to hydrophobic surfaces.
In competitive mode, in solution containing both fibronectin and albumin, fibronectin showed greater adsorption on hydrophilic
surfaces, whereas Alb predominantly adsorbed on hydrophobic
surfaces. Initial attachment of both cells increased with increase in
surface wettability, in particular, on super-hydrophilic surface, which
correlated well with fibronectin adsorption in competitive mode.
These results suggest that a cold plasma-surface modification enabled
to regulate the surface wettability, and fibronectin adsorption may be
responsible for increasing cell adhesion on hydrophilic surfaces in a
body fluid
Abstract: In this paper, periodic force operation of a wastewater treatment process has been studied for the improved process performance. A previously developed dynamic model for the process is used to conduct the performance analysis. The static version of the model was utilized first to determine the optimal productivity conditions for the process. Then, feed flow rate in terms of dilution rate i.e. (D) is transformed into sinusoidal function. Nonlinear model predictive control algorithm is utilized to regulate the amplitude and period of the sinusoidal function. The parameters of the feed cyclic functions are determined which resulted in improved productivity than the optimal productivity under steady state conditions. The improvement in productivity is found to be marginal and is satisfactory in substrate conversion compared to that of the optimal condition and to the steady state condition, which corresponds to the average value of the periodic function. Successful results were also obtained in the presence of modeling errors and external disturbances.
Abstract: Typically thermal power plants are located near to
surface coal mines that produce huge amount of fly ash as a waste
byproduct. Disposal of fly ash causes significant economic and
environmental problems. Now-a-days, research is going on for bulk
utilization of fly ash. In order to increase its percentage utilization, an
investigation was carried out to evaluate its potential for haul road
construction. This paper presents the laboratory California bearing
ratio (CBR) tests and evaluates the effect of lime on CBR behavior of
fly ash - mine overburden mixes. Tests were performed with different
percentages of lime (2%, 3%, 6%, and 9%). The results show that the
increase in bearing ratio of fly ash-overburden mixes was achieved
by lime treatment. Scanning electron microscopy (SEM) analyses
were conducted on 28 days cured specimens. The SEM study showed
that the bearing ratio development is related to the microstructural
development.
Abstract: In order to evaluate the relationship between the sulphur (S), glucose (G), nitrogen (N) and plant residues (st), sulphur immobilization and microbial transformation were monitored in five soil samples from 0-30 cm of Bastam farmers fields of Shahrood area following 11 treatments with different levels of Sulphur (S), glucose (G), N and plant residues (wheat straw) in a randomized block design with three replications and incubated over 20, 45 and 60 days, the immobilization of SO4 -2-S presented as a percentage of that added, was inversely related to its addition rate. Additions of glucose and plant residues increased with the C-to-S ratio of the added amendments, irrespective of their origins (glucose and plant residues). In the presence of C sources (glucose or plant residues). N significantly increased the immobilization of SO4 -2-S, whilst the effect of N was insignificant in the absence of a C amendment. In first few days the amounts of added SO4 -2-S immobilized were linearly correlated with the amounts of added S recovered in the soil microbial biomass. With further incubation the proportions of immobilized SO4 -2-S remaining as biomass-S decreased. Decrease in biomass-S was thought to be due to the conversion of biomass-S into soil organic-S. Glucose addition increased the immobilization (microbial utilization and incorporation into the soil organic matter) of native soil SO4 -2-S. However, N addition enhance the mineralization of soil organic-S, increasing the concentration of SO4 - 2-S in soil.
Abstract: This study was set to determine the antimicrobial
activities of brine salting, chlorinated solution, and oil frying
treatments on enteric bacteria and fungi in Rastrineobola argentea
fish from fish landing beaches within L. Victoria basin of western
Kenya. Statistical differences in effectiveness of the different
treatment methods was determined by single factor ANOVA, and
paired two-tail t-Test was performed to compare the differences in
moisture contents before and after storage. Oil fried fish recorded the
lowest microbial loads, sodium chloride at 10% concentration was
the second most effective and chlorinated solution even at 150ppm
was the least effective against the bacteria and fungi in fish. Moisture
contents of the control and treated fish were significantly lower after
storage. These results show that oil frying of fish should be adopted
for processing and preserving Rastrineobola argentea which is the
most abundant and affordable fish species from Lake Victoria.
Abstract: Thermo-chemical treatment (TCT) such as pyrolysis
is getting recognized as a valid route for (i) materials and valuable
products and petrochemicals recovery; (ii) waste recycling; and (iii)
elemental characterization. Pyrolysis is also receiving renewed
attention for its operational, economical and environmental
advantages. In this study, samples of polyethylene terephthalate
(PET) and polystyrene (PS) were pyrolysed in a microthermobalance
reactor (using a thermogravimetric-TGA setup). Both
polymers were prepared and conditioned prior to experimentation.
The main objective was to determine the kinetic parameters of the
depolymerization reactions that occur within the thermal degradation
process. Overall kinetic rate constants (ko) and activation energies
(Eo) were determined using the general kinetics theory (GKT)
method previously used by a number of authors. Fitted correlations
were found and validated using the GKT, errors were within ± 5%.
This study represents a fundamental step to pave the way towards the
development of scaling relationship for the investigation of larger
scale reactors relevant to industry.