Abstract: It has been established that microRNAs (miRNAs) play
an important role in gene expression by post-transcriptional regulation
of messengerRNAs (mRNAs). However, the precise relationships
between microRNAs and their target genes in sense of numbers,
types and biological relevance remain largely unclear. Dissecting the
miRNA-target relationships will render more insights for miRNA
targets identification and validation therefore promote the understanding
of miRNA function. In miRBase, miRanda is the key
algorithm used for target prediction for Zebrafish. This algorithm
is high-throughput but brings lots of false positives (noise). Since
validation of a large scale of targets through laboratory experiments
is very time consuming, several computational methods for miRNA
targets validation should be developed. In this paper, we present an
integrative method to investigate several aspects of the relationships
between miRNAs and their targets with the final purpose of extracting
high confident targets from miRanda predicted targets pool. This is
achieved by using the techniques ranging from statistical tests to
clustering and association rules. Our research focuses on Zebrafish.
It was found that validated targets do not necessarily associate with
the highest sequence matching. Besides, for some miRNA families,
the frequency of their predicted targets is significantly higher in the
genomic region nearby their own physical location. Finally, in a case
study of dre-miR-10 and dre-miR-196, it was found that the predicted
target genes hoxd13a, hoxd11a, hoxd10a and hoxc4a of dre-miR-
10 while hoxa9a, hoxc8a and hoxa13a of dre-miR-196 have similar
characteristics as validated target genes and therefore represent high
confidence target candidates.
Abstract: With increasing utilization of the wireless devices in
different fields such as medical devices and industrial fields, the
paper presents a method for simplify the Bluetooth packets with
throughput enhancing. The paper studies a vital issue in wireless
communications, which is the throughput of data over wireless
networks. In fact, the Bluetooth and ZigBee are a Wireless Personal
Area Network (WPAN). With taking these two systems competition
consideration, the paper proposes different schemes for improve the
throughput of Bluetooth network over a reliable channel. The
proposition depends on the Channel Quality Driven Data Rate
(CQDDR) rules, which determines the suitable packet in the
transmission process according to the channel conditions. The
proposed packet is studied over additive White Gaussian Noise
(AWGN) and fading channels. The Experimental results reveal the
capability of extension of the PL length by 8, 16, 24 bytes for classic
and EDR packets, respectively. Also, the proposed method is suitable
for the low throughput Bluetooth.
Abstract: A new code synchronization algorithm is proposed in
this paper for the secondary cell-search stage in wideband CDMA
systems. Rather than using the Cyclically Permutable (CP) code in the
Secondary Synchronization Channel (S-SCH) to simultaneously
determine the frame boundary and scrambling code group, the new
synchronization algorithm implements the same function with less
system complexity and less Mean Acquisition Time (MAT). The
Secondary Synchronization Code (SSC) is redesigned by splitting into
two sub-sequences. We treat the information of scrambling code group
as data bits and use simple time diversity BCH coding for further
reliability. It avoids involved and time-costly Reed-Solomon (RS)
code computations and comparisons. Analysis and simulation results
show that the Synchronization Error Rate (SER) yielded by the new
algorithm in Rayleigh fading channels is close to that of the
conventional algorithm in the standard. This new synchronization
algorithm reduces system complexities, shortens the average
cell-search time and can be implemented in the slot-based cell-search
pipeline. By taking antenna diversity and pipelining correlation
processes, the new algorithm also shows its flexible application in
multiple antenna systems.
Abstract: The study of the variability of the postural strategies
in low back pain patients, as a criterion in evaluation of the
adaptability of this system to the environmental demands is the
purpose of this study. A cross-sectional case-control study was
performed on 21 recurrent non-specific low back pain patients and 21
healthy volunteers. The electromyography activity of Deltoid,
External Oblique (EO), Transverse Abdominis/Internal Oblique
(TrA/IO) and Erector Spine (ES) muscles of each person was
recorded in 75 rapid arm flexion with maximum acceleration.
Standard deviation of trunk muscles onset relative to deltoid muscle
onset were statistically analyzed by MANOVA . The results show
that chronic low back pain patients exhibit less variability in their
anticipatory postural adjustments (APAs) in comparison with the
control group. There is a decrease in variability of postural control
system of recurrent non-specific low back pain patients that can
result in the persistence of pain and chronicity by decreasing the
adaptability to environmental demands.
Abstract: The use of Electronic Commerce (EC)
technologies enables Small Medium Enterprises (SMEs) to improve their efficiency and competitive position. Much of the literature proposes an extensive set of benefits for
organizations that choose to adopt and implement ECommerce
systems. Factors of Business –to-business (B2B)
E-Commerce adoption and implementation have been
extensively investigated. Despite enormous attention given to encourage Small Medium Enterprises (SMEs) to adopt and
implement E-Commerce, little research has been carried out in identifying the factors of Business-to-Consumer ECommerce adoption and implementation for SMEs. To conduct the study, Tornatsky and Fleischer model was adopted
and tested in four SMEs located in Christchurch, New
Zealand. This paper explores the factors that impact the
decision and method of adoption and implementation of ECommerce
systems in automobile industry. Automobile
industry was chosen because the product they deal with i.e.
cars are not a common commodity to be sold online, despite this fact the eCommerce penetration in automobile industry is
high. The factors that promote adoption and implementation of
E-Commerce technologies are discussed, together with the
barriers. This study will help SME owners to effectively
handle the adoption and implementation process and will also
improve the chance of successful E-Commerce
implementation. The implications of the findings for
managers, consultants, and government organizations engaged in promoting E-Commerce adoption and implementation in
small businesses and future research are discussed.
Abstract: An experiment was conducted with 80 unsexed
broilers of the Arbor Acress strain to determine the capability of a
carrot and fruit juice wastes mixture (carrot, apple, manggo, avocado,
orange, melon and Dutch egg plant) in the same proportion for
replacing corn in broiler diet. This study involved a completely
randomized design (CRD) with 5 treatments (0, 5, 10, 15, and 20% of
juice wastes mixture in diets) and 4 replicates per treatment. Diets
were isonitrogenous (22% crude protein) and isocaloric (3000 kcal/kg
diet). Measured variables were feed consumption, average daily
gain, feed conversion, as well as percentages of abdominal fat pad,
carcass, digestive organs (liver, pancreas and gizzard), and heart.
Data were analyzed by analysis of variance for CRD. Increasing
juice wastes mixture levels in diets increased feed consumption
(P
Abstract: The purpose of this paper is to introduce an interactive online case-study library website developed in a national project. The design goal of the website is to provide interactive, enhanced, case-based and online educational resource for educators through the purpose and within the scope of a national project. The ADDIE instructional design model was used in the development of the website for interactive case-based library. This library is developed on a web-based platform, which is important in terms of manageability, accessibility, and updateability of data. Users are able to sort the displayed case-studies by their titles, dates, ratings, view counts, etc. The usability test is used and the expert opinion is taken for the evaluation of the website. This website is a tool to integrate technology into education. It is believed that this website will be beneficial for pre-service and in-service teachers in terms of their professional developments.
Abstract: The paper proposes a novel technique for iris
recognition using texture and phase features. Texture features are
extracted on the normalized iris strip using Haar Wavelet while phase
features are obtained using LOG Gabor Wavelet. The matching
scores generated from individual modules are combined using sum of
score technique. The system is tested on database obtained from Bath
University and Indian Institute of Technology Kanpur and is giving
an accuracy of 95.62% and 97.66% respectively. The FAR and FRR
of the combined system is also reduced comparatively.
Abstract: The objective of this work is to show a procedure for
mesh generation in a fluidized bed using large eddy simulations
(LES) of a filtered two-fluid model. The experimental data were
obtained by [1] in a laboratory fluidized bed. Results show that it is
possible to use mesh with less cells as compared to RANS turbulence
model with granular kinetic theory flow (KTGF). Also, the numerical
results validate the experimental data near wall of the bed, which
cannot be predicted by RANS.model.
Abstract: Mycophenolic acid “MPA" is a secondary metabolite
of Penicillium bervicompactum with antibiotic and
immunosuppressive properties. In this study, fermentation process
was established for production of mycophenolic acid by Penicillium
bervicompactum MUCL 19011 in shake flask. The maximum MPA
production, product yield and productivity were 1.379 g/L, 18.6 mg/g
glucose and 4.9 mg/L.h respectively. Glucose consumption, biomass
and MPA production profiles were investigated during fermentation
time. It was found that MPA production starts approximately after
180 hours and reaches to a maximum at 280 h. In the next step, the
effects of methionine and acetate concentrations on MPA production
were evaluated. Maximum MPA production, product yield and
productivity (1.763 g/L, 23.8 mg/g glucose and 6.30 mg/L. h
respectively) were obtained with using 2.5 g/L methionine in culture
medium. Further addition of methionine had not more positive effect
on MPA production. Finally, results showed that the addition of
acetate to the culture medium had not any observable effect on MPA
production.
Abstract: In this paper the development of neural network based fuzzy inference system for electricity consumption prediction is considered. The electricity consumption depends on number of factors, such as number of customers, seasons, type-s of customers, number of plants, etc. It is nonlinear process and can be described by chaotic time-series. The structure and algorithms of neuro-fuzzy system for predicting future values of electricity consumption is described. To determine the unknown coefficients of the system, the supervised learning algorithm is used. As a result of learning, the rules of neuro-fuzzy system are formed. The developed system is applied for predicting future values of electricity consumption of Northern Cyprus. The simulation of neuro-fuzzy system has been performed.
Abstract: Multi-loop (De-centralized) Proportional-Integral-
Derivative (PID) controllers have been used extensively in process
industries due to their simple structure for control of multivariable
processes. The objective of this work is to design multiple-model
adaptive multi-loop PID strategy (Multiple Model Adaptive-PID)
and neural network based multi-loop PID strategy (Neural Net
Adaptive-PID) for the control of multivariable system. The first
method combines the output of multiple linear PID controllers,
each describing process dynamics at a specific level of operation.
The global output is an interpolation of the individual multi-loop
PID controller outputs weighted based on the current value of the
measured process variable. In the second method, neural network
is used to calculate the PID controller parameters based on the
scheduling variable that corresponds to major shift in the process
dynamics. The proposed control schemes are simple in structure with
less computational complexity. The effectiveness of the proposed
control schemes have been demonstrated on the CSTR process,
which exhibits dynamic non-linearity.
Abstract: Perhaps no single issue has been cited as either the root
cause and / or the greatest challenge to the restructured power system then the lack of adequate reliable transmission. Probabilistic transmission planning has become increasingly necessary and important in recent
years. The transmission planning analysis carried out by the authors,
spans a 10-year horizon, taking into consideration a value of 2 % load
increase / year at each consumer. Taking into consideration this increased
load, a probabilistic power flow was carried out, all the system components
being regarded from probabilistic point of view. Several contingencies
have been generated, for assessing the security of the power system. The results have been analyzed and several important conclusions were pointed. The objective is to achieve a network that works without limit violations for all (or most of) scenario realizations. The case study is represented by the IEEE 14 buses test power system.
Abstract: Stability of functionally graded beams with piezoelectric layers subjected to axial compressive load that is simply supported at both ends is studied in this paper. The displacement field of beam is assumed based on first order shear deformation beam theory. Applying the Hamilton's principle, the governing equation is established. The influences of applied voltage, dimensionless geometrical parameter, functionally graded index and piezoelectric thickness on the critical buckling load of beam are presented. To investigate the accuracy of the present analysis, a compression study is carried out with a known data.
Abstract: This paper discusses the classification process for medical data. In this paper, we use the data from ACM KDDCup 2008 to demonstrate our classification process based on latent topic discovery. In this data set, the target set and outliers are quite different in their nature: target set is only 0.6% size in total, while the outliers consist of 99.4% of the data set. We use this data set as an example to show how we dealt with this extremely biased data set with latent topic discovery and noise reduction techniques. Our experiment faces two major challenge: (1) extremely distributed outliers, and (2) positive samples are far smaller than negative ones. We try to propose a suitable process flow to deal with these issues and get a best AUC result of 0.98.
Abstract: Abrasive waterjet cutting (AWJ) is a highly efficient
method for cutting almost any type of material. When holes shall be
cut the waterjet first needs to pierce the material.This paper presents a
vast experimental analysis of piercing parameters effect on piercing
time. Results from experimentation on feed rates, work piece
thicknesses, abrasive flow rates, standoff distances and water
pressure are also presented as well as studies on three methods for
dynamic piercing. It is shown that a large amount of time and
resources can be saved by choosing the piercing parameters in a
correct way. The large number of experiments puts demands on the
experimental setup. An automated experimental setup including
piercing detection is presented to enable large series of experiments
to be carried out efficiently.
Abstract: This study suggests a model of a new set of evaluation criteria that will be used to measure the efficiency of real-world E-commerce websites. Evaluation criteria include design, usability and performance for websites, the Data Envelopment Analysis (DEA) technique has been used to measure the websites efficiency. An efficient Web site is defined as a site that generates the most outputs, using the smallest amount of inputs. Inputs refer to measurements representing the amount of effort required to build, maintain and perform the site. Output is amount of traffic the site generates. These outputs are measured as the average number of daily hits and the average number of daily unique visitors.
Abstract: The scientific perspective, the practice area of physical education and sports activities improve power capacity in all its forms of expression, being a generator of the research topics. Today theories that strength training athletes and slow down development progress will affect the strength and flexibility are discredited. On the other hand there are sectors and / or samples whose results are sports of the way higher manifestation of power as a result of the composition of the force and velocity, being based in this respect on the systematic and continuous development of both bio-motric capacities said. Training of force for children was and is controversial. Teama de accidentări sau a stopării premature a procesului de creştere a făcut ca în trecut copiii să fie ţinuţi departe de lucrul cu diferite greutăţi.Fear of injury or premature stop the growth process in the past made the children to be kept away from working with different weights. Recent studies have shown that the risk of accidents is relatively small and the strength training can help prevent them. For example, most accidents occur at the level of athletics ligaments and tendons. From this point of view, it can be said that a progressive intervention of force training, optimal design, will help enhancing their process, such as athlete much better prepared to meet training requests and competitions. Preparation of force provides a solid basis for further phases in the highest performance.
Abstract: Carbon fibers are fabricated from different materials,
such as special polyacrylonitrile (PAN) fibers, rayon fibers and pitch.
Among these three groups of materials, PAN fibers are the most
widely used precursor for the manufacture of carbon fibers. The
process of fabrication carbon fibers from special PAN fibers includes
two steps; oxidative stabilization at low temperature and
carbonization at high temperatures in an inert atmosphere. Due to the
high price of raw materials (special PAN fibers), carbon fibers are
still expensive.
In the present work the main goal is making carbon fibers from
low price commercial PAN fibers with modified chemical
compositions. The results show that in case of conducting completes
stabilization process, it is possible to produce carbon fibers with
desirable tensile strength from this type of PAN fibers. To this
matter, thermal characteristics of commercial PAN fibers were
investigated and based upon the obtained results, with some changes
in conventional procedure of stabilization in terms of temperature
and time variables; the desirable conditions of complete stabilization
is achieved.
Abstract: In this paper a systematic method via H∞ control
design is proposed to select a sensor set that satisfies a number
of input criteria for a MAGLEV suspension system. The proposed
method recovers a number of optimised controllers for each possible
sensor set that satisfies the performance and constraint criteria using
evolutionary algorithms.