Abstract: The seismic responses of steel buildings with semirigid
post-tensioned connections (PC) are estimated and compared
with those of steel buildings with typical rigid (welded) connections
(RC). The comparison is made in terms of global and local response
parameters. The results indicate that the seismic responses in terms of
interstory shears, roof displacements, axial load and bending
moments are smaller for the buildings with PC connection. The
difference is larger for global than for local parameters, which in turn
varies from one column location to another. The reason for this
improved behavior is that the buildings with PC dissipate more
hysteretic energy than those with RC. In addition, unlike the case of
buildings with WC, for the PC structures the hysteretic energy is
mostly dissipated at the connections, which implies that structural
damage in beams and columns is not significant. According to these
results, steel buildings with PC are a viable option in high seismicity
areas because of their smaller response and self-centering connection
capacity as well as the fact that brittle failure is avoided.
Abstract: Risk analysis is considered as a fundamental aspect
relevant for ensuring the level of critical infrastructure protection,
where the critical infrastructure is seen as system, asset or its part
which is important for maintaining the vital societal functions. Article
actually discusses and analyzes the potential application of selected
tools of information support for the implementation and within the
framework of risk analysis and critical infrastructure protection. Use
of the information in relation to their risk analysis can be viewed as a
form of simplifying the analytical process. It is clear that these
instruments (information support) for these purposes are countless, so
they were selected representatives who have already been applied in
the selected area of critical infrastructure, or they can be used. All
presented fact were the basis for critical infrastructure resilience
evaluation methodology development.
Abstract: Doxorubicin, also known as Adriamycin, is an
anthracycline class of drug used in cancer chemotherapy. It is used in
the treatment of non-Hodgkin’s lymphoma, multiple myeloma, acute
leukemia, breast cancer, lung cancer, endometrium cancer and ovary
cancers. It functions via intercalating DNA and ultimately killing
cancer cells. The major side effects of doxorubicin are hair loss,
myelosuppression, nausea & vomiting, oesophagitis, diarrhea, heart
damage and liver dysfunction. The minor modifications in the
structure of compound exhibit large variation in the biological
activity, has prompted us to carry out the synthesis of sulfonamide
derivatives. Sulfonamide is an important feature with broad spectrum
of biological activity such as antiviral, antifungal, diuretics, antiinflammatory,
antibacterial and anticancer activities. Structure of the
synthesized compound N-(1-methyl-2-oxo-2-N-methyl anilinoethyl)
benzene sulfonamide confirmed by proton nuclear magnetic
resonance (1H NMR),13C NMR, Mass and FTIR spectroscopic tools
to assure the position of all protons and hence stereochemistry of the
molecule. Further we have reported the binding potential of
synthesized sulfonamide analogues in comparison to doxorubicin
drug using Auto Dock 4.2 software. Computational binding energy
(B.E.) and inhibitory constant (Ki) has been evaluated for the
synthesized compound in comparison of doxorubicin against Poly
(dA-dT).Poly (dA-dT) and Poly (dG-dC).Poly (dG-dC) sequences.
The in vitro cytotoxic study against human breast cancer cell lines
confirms the better anticancer activity of the synthesized compound
over currently in use anticancer drug doxorubicin. The IC50 value of
the synthesized compound is 7.12 μM whereas for doxorubicin is 7.2
μM.
Abstract: In reference to the legal state in the Thai legal system,
most people understand the minor principles of the legal state form,
which are the principles that can be explained and understood easily
and the results can be seen clearly, especially in the legitimacy of
administrative acts. Therefore, there is no awareness of justice, which
is the fundamental value of Thai law. The legitimacy of administrative
acts requires the administration to adhere to the constitution and
legislative laws in enforcement of the laws. If it appears that the
administrative acts are illegitimate, the administrative court, as the
court of justice, will revoke those acts as if they had never been set in
the legal system, this will affect people’s trust as they are unaware as
to whether the administrative acts that appoint their lives are
legitimate or not. Regarding the revocation of administrative orders
by the administrative court as if those orders had never existed, the
common individual surely cannot be expected to comprehend the
security of their juristic position. Therefore, the legal state does not
require a revocation of the government’s acts to terminate its legal
results merely because those acts are illegitimate, but there should be
considerations and realizations regarding the “The Principle of the
Protection of Legitimate Expectation,” which is a minor principle in
the legal state’s content that focuses on supporting and protecting
legitimate expectations of the juristic position of an individual and
maintaining justice, which is the fundamental value of Thai law.
Abstract: Fluid viscous damping systems are well suited for
many air vehicles subjected to shock and vibration. These damping
system work with the principle of viscous fluid throttling through the
orifice to create huge pressure difference between compression and
rebound chamber and obtain the required damping force. One
application of such systems is its use in aircraft door system to
counteract the door’s velocity and safely stop it. In exigency
situations like crash or emergency landing where the door doesn’t
open easily, possibly due to unusually tilting of fuselage or some
obstacles or intrusion of debris obstruction to move the parts of the
door, such system can be combined with other systems to provide
needed force to forcefully open the door and also securely stop it
simultaneously within the required time i.e. less than 8 seconds. In
the present study, a hydraulic system called snubber along with other
systems like actuator, gas bottle assembly which together known as
emergency power assist system (EPAS) is designed, built and
experimentally studied to check the magnitude of angular velocity,
damping force and time required to effectively open the door.
Whenever needed, the gas pressure from the bottle is released to
actuate the actuator and at the same time pull the snubber’s piston to
operate the emergency opening of the door. Such EPAS installed in
the suspension arm of the aircraft door is studied explicitly changing
parameters like orifice size, oil level, oil viscosity and bypass valve
gap and its spring of the snubber at varying temperature to generate
the optimum design case. Comparative analysis of the EPAS at
several cases is done and conclusions are made. It is found that
during emergency condition, the system opening time and angular
velocity, when snubber with 0.3mm piston and shaft orifice and
bypass valve gap of 0.5 mm with its original spring is used, shows
significant improvement over the old ones.
Abstract: This research was conducted in the Mae Sot
Watershed where located in the Moei River Basin at the Upper
Salween River Basin in Tak Province, Thailand. The Mae Sot
Municipality is the largest urban area in Tak Province and situated in
the midstream of the Mae Sot Watershed. It usually faces flash flood
problem after heavy rain due to poor flood management has been
reported since economic rapidly bloom up in recent years. Its
catchment can be classified as ungauged basin with lack of rainfall
data and no any stream gaging station was reported. It was attached
by most severely flood events in 2013 as the worst studied case for
all those communities in this municipality. Moreover, other problems
are also faced in this watershed, such shortage water supply for
domestic consumption and agriculture utilizations including a
deterioration of water quality and landslide as well. The research
aimed to increase capability building and strengthening the
participation of those local community leaders and related agencies to
conduct better water management in urban area was started by mean
of the data collection and illustration of the appropriated application
of some short period rainfall forecasting model as they aim for better
flood relief plan and management through the hydrologic model
system and river analysis system programs. The authors intended to
apply the global rainfall data via the integrated data viewer (IDV)
program from the Unidata with the aim for rainfall forecasting in a
short period of 7-10 days in advance during rainy season instead of
real time record. The IDV product can be present in an advance
period of rainfall with time step of 3-6 hours was introduced to the
communities. The result can be used as input data to the hydrologic
modeling system model (HEC-HMS) for synthesizing flood
hydrographs and use for flood forecasting as well. The authors
applied the river analysis system model (HEC-RAS) to present flood
flow behaviors in the reach of the Mae Sot stream via the downtown
of the Mae Sot City as flood extents as the water surface level at
every cross-sectional profiles of the stream. Both models of HMS and
RAS were tested in 2013 with observed rainfall and inflow-outflow
data from the Mae Sot Dam. The result of HMS showed fit to the
observed data at the dam and applied at upstream boundary discharge
to RAS in order to simulate flood extents and tested in the field, and
the result found satisfying. The product of rainfall from IDV was fair
while compared with observed data. However, it is an appropriate
tool to use in the ungauged catchment to use with flood hydrograph
and river analysis models for future efficient flood relief plan and
management.
Abstract: Remote sensing plays a vital role in mapping of
resources and monitoring of environments of the earth. In the present
research study, mapping and monitoring of clay siltations occurred in
the Alkhod Dam of Muscat, Sultanate of Oman are carried out using
low-cost multispectral Landsat and ASTER data. The dam is
constructed across the Wadi Samail catchment for ground water
recharge. The occurrence and spatial distribution of siltations in the
dam are studied with five years of interval from the year 1987 of
construction to 2014. The deposits are mainly due to the clay, sand
and silt occurrences derived from the weathering rocks of ophiolite
sequences occurred in the Wadi Samail catchment. The occurrences
of clays are confirmed by minerals identification using ASTER
VNIR-SWIR spectral bands and Spectral Angle Mapper supervised
image processing method. The presence of clays and their spatial
distribution are verified in the field. The study recommends the
technique and the low-cost satellite data to similar region of the
world.
Abstract: Since, it is essential to provide homeless people by the
earthquake with safe, habitable accommodation repairing medium
and slight levels of damage at the connection parts should be
undertaken. In order to prove that a repaired connection was
sufficiently strong, a precast beam to column post tensioned
connection was tested in three phases. In phase one, the middle level
damage was observed at 6% drift at these connections. As a result of
the extra loads applied, little damage was observed. In the last phase,
the four connections tested in the first phase were repaired using
epoxy resin and then retested. The results from the tests on the
repaired precast and the undamaged specimens showed that the
repaired specimens were sufficiently strong, thus proving that repair
to damaged precast beam to column post tensioned connections can
be undertaken.
Abstract: The main aim of this research was to investigate a
prototype bamboo shading device. There were two objectives to this
study: first, to investigate the effects of non-chemical treatments on
bamboo shading devices damaged by powder-post beetles and fungi,
and second to develop a prototype bamboo shading device. This
study of the effects of non-chemical treatments on bamboo shading
devices damage by powder-post beetles in the laboratory showed
that, among seven treatments tested, wood vinegar treatment can
protect powder-post beetles better than the original method by up to
92.91%. It was also found that wood vinegar treatment shows the
best performance in fungi protection and works better than the
original method by up to 40%. A second experiment was carried out
by constructing four bamboo shading devices and installing them on
a building for 28 days. All aspects of shading device were
investigated in terms of their beauty, durability, and ease of
construction and assembly. The final prototype was developed from
the lessons learned from the test results. In conclusion, this study
showed the effectiveness of some natural preservatives against insect
and fungi damage, and it also illustrated the characteristics of a
prototype bamboo shading device that can be constructed by rural
workers within one week.
Abstract: The purpose of this paper is to examine the hypothesis
explaining the mechanism in the case, where the product is deleted or
reduced the fundamental function of the product through the product
concept changes in the digital camera industry. This paper points out
not owning the fundamental technology might cause the change of the
product concept. Casio could create new competitive factor so that this
paper discusses a possibility of the mechanism of changing the product
concept.
Abstract: The wear measuring and wear modelling are
fundamental issues in the industrial field, mainly correlated to the
economy and safety. Therefore, there is a need to study the wear
measurements and wear estimation. Pin-on-disc test is the most
common test which is used to study the wear behaviour. In this paper,
the pin-on-disc (AEROTECH UNIDEX 11) is used for the
investigation of the effects of normal load and hardness of material on
the wear under dry and sliding conditions. In the pin-on-disc rig, two
specimens were used; one, a pin is made of steel with a tip, positioned
perpendicular to the disc, where the disc is made of aluminium. The
pin wear and disc wear were measured by using the following
instruments: The Talysurf instrument, a digital microscope, and the
alicona instrument. The Talysurf profilometer was used to measure
the pin/disc wear scar depth, digital microscope was used to measure
the diameter and width of wear scar, and the alicona was used to
measure the pin wear and disc wear. After that, the Archard model,
American Society for Testing and Materials model (ASTM), and
neural network model were used for pin/disc wear modelling.
Simulation results were implemented by using the Matlab program.
This paper focuses on how the alicona can be used for wear
measurements and how the neural network can be used for wear
estimation.
Abstract: Agriculture is the backbone of economy of Pakistan
and cotton is the major agricultural export and supreme source of raw
fiber for our textile industry. To combat severe problems of insect
and weed, combination of three genes namely Cry1Ac, Cry2A and
EPSPS genes was transferred in locally cultivated cotton variety
MNH-786 with the use of Agrobacterium mediated genetic
transformation. The present study focused on the molecular screening
of transgenic cotton plants at T3 generation in order to confirm
integration and expression of all three genes (Cry1Ac, Cry2A and
EPSP synthase) into the cotton genome. Initially, glyphosate spray
assay was used for screening of transgenic cotton plants containing
EPSP synthase gene at T3 generation. Transgenic cotton plants which
were healthy and showed no damage on leaves were selected after 07
days of spray. For molecular analysis of transgenic cotton plants in
the laboratory, the genomic DNA of these transgenic cotton plants
were isolated and subjected to amplification of the three genes. Thus,
seventeen out of twenty (Cry1Ac gene), ten out of twenty (Cry2A
gene) and all twenty (EPSP synthase gene) were produced positive
amplification. On the base of PCR amplification, ten transgenic plant
samples were subjected to protein expression analysis through
ELISA. The results showed that eight out of ten plants were actively
expressing the three transgenes. Real-time PCR was also done to
quantify the mRNA expression levels of Cry1Ac and EPSP synthase
gene. Finally, eight plants were confirmed for the presence and active
expression of all three genes at T3 generation.
Abstract: This study examines analytically the effect of tsunami loads on reinforced concrete (RC) frame buildings. The impact of tsunami wave loads and waterborne objects are analyzed using a typical substandard full-scale two-story RC frame building tested as part of the EU-funded Ecoleader project. The building was subjected to shake table tests in bare condition, and subsequently strengthened using Carbon Fiber Reinforced Polymers (CFRP) composites and retested. Numerical models of the building in both bare and CFRP-strengthened conditions are calibrated in DRAIN-3DX software to match the test results. To investigate the response of wave loads and impact forces, the numerical models are subjected to nonlinear dynamic analyses using force time-history input records. The analytical results are compared in terms of displacements at the floors and at the “impact point” of a boat. The results show that the roof displacement of the CFRP-strengthened building reduced by 63% when compared to the bare building. The results also indicate that strengthening only the mid-height of the impact column using CFRP is more effective at reducing damage when compared to strengthening other parts of the column. Alternative solutions to mitigate damage due to tsunami loads are suggested.
Abstract: This paper examines how “Zakat” provides fair
income redistribution and aids the struggle against poverty. Providing
fair income redistribution and combating poverty constitutes some of
the fundamental tasks performed by countries all over the world.
Each country seeks a solution for these problems according to their
political, economic and administrative styles through applying
various economic and financial policies. The same situation can be
handled via “zakat” association in Islam. Nowadays, we observe
different versions of “zakat” in developed countries. Applications
such as negative income tax denote merely a different form of
“zakat” that is being applied almost in the same way but under
changed names. However, the minimum values to donate under zakat
(e.g. 85 gr. gold and 40 animals) get altered and various amounts are
put into practice. It might be named as negative income tax instead of
zakat, nonetheless, these applications are based on the Holy Koran
and the hadith released 1400 years ago. Besides, considering the
savage and slavery in the world at those times, we might easily
recognize the true value of the zakat being applied for the first time
then in the Islamic system. Through zakat, governments are able to
transfer incomes to the poor as a means of enabling them achieve the
minimum standard of living required. With regards to who benefits
from the Zakat, an objective and fair criteria was used to determine
who benefits from the zakat contrary to the notion that it was based
on peoples’ own choices. Since the zakat is obligatory, the transfers
do not get forwarded directly but via the government and get
distributed, which requires vast governmental organizations. Through
the application of Zakat, reduced levels of poverty can be achieved
and also ensure the fair income redistribution.
Abstract: Qatar, a Gulf country highly dependent on its oil and
gas revenues – is looking to innovate, diversify, and ultimately reach
its aim of creating a knowledge economy to prepare for its post-oil
era. One area that the country is investing in is Contemporary Art,
and world renowned artists such as Damien Hirst and Richard Serra –
have been commissioned to design site-specific art for the public
spaces of the city of Doha as well as in more remote desert locations.
This research discusses the changing presence, role and context of
public art in Doha, both from a historical and cultural overview, and
the different forms and media as well as the typologies of urban and
public spaces in which the art is installed. It examines the process of
implementing site-specific artworks, looking at questions of scale,
history, social meaning and formal aesthetics. The methodologies
combine theoretical research on the understanding of public art and
its role and placement in public space, as well as empirical research
on contemporary public art projects in Doha, based on documentation
and interviews and as well as site and context analysis of the urban or
architectural spaces within which the art is situated. Surveys and
interviews – using social media - in different segments of the
contemporary Qatari society, including all nationalities and social
groups, are used to measure and qualify the impacts and effects on
the population.
Abstract: In this investigation, we have evaluated the effects of
arsenic trioxide on hepatic function in pregnant and lactating Swiss
albino mice and their suckling pups. Experiments were carried out on
female mice given 175 ppm As2O3 in their drinking water from the
14th day of pregnancy until day 14 after delivery. Our results showed
a significant decrease in plasma levels of total protein and albumin,
cholesterol and triglyceride in As2O3 treated mice and their pups. The
hyperbilirubinemia and the increased plasma total alkaline
phosphatase activity suggested the presence of cholestasis.
Transaminase activities as well as lactate deshydrogenase activity in
plasma, known as biomarkers of hepatocellular injury, were elevated
indicating hepatic cells’ damage after treatment with As2O3.
Exposure to arsenic led to an increase of liver thiobarbituric acid
reactive substances level along with a concomitant decrease in the
activities of superoxide dismutase, catalase and glutathione
peroxidase and in glutathione.
Abstract: The aim of this paper is to perform experimental
modal analysis (EMA) of reinforced concrete (RC) square slabs.
EMA is the process of determining the modal parameters (Natural
Frequencies, damping factors, modal vectors) of a structure from a
set of frequency response functions FRFs (curve fitting). Although,
experimental modal analysis (or modal testing) has grown steadily in
popularity since the advent of the digital FFT spectrum analyzer in
the early 1970’s, studying all types of members and materials using
such method have not yet been well documented. Therefore, in this
work, experimental tests were conducted on RC square slab
specimens of dimensions 600mm x 600mmx 40mm. Experimental
analysis was based on freely supported boundary condition.
Moreover, impact testing as a fast and economical means of finding
the modes of vibration of a structure was used during the
experiments. In addition, Pico Scope 6 device and MATLAB
software were used to acquire data, analyze and plot Frequency
Response Function (FRF). The experimental natural frequencies
which were extracted from measurements exhibit good agreement
with analytical predictions. It is showed that EMA method can be
usefully employed to investigate the dynamic behavior of RC slabs.
Abstract: Graphical User Interface (GUI) is essential to
programming, as is any other characteristic or feature, due to the fact
that GUI components provide the fundamental interaction between
the user and the program. Thus, we must give more interest to GUI
during building and development of systems. Also, we must give a
greater attention to the user who is the basic corner in the dealing
with the GUI. This paper introduces an approach for designing GUI
from one of the models of business workflows which describe the
workflow behavior of a system, specifically through Activity
Diagrams (AD).
Abstract: Although, arsenic trioxide has been the subject of
toxicological research, in vitro cytotoxicity and genotoxicity studies
using relevant cell models and uniform methodology are not well
elucidated. Hence, the aim of the present study was to evaluate the
cytotoxicity and genotoxicity induced by arsenic trioxide in human
keratinocytes (HaCaT) using the MTT [3-(4, 5-dimethylthiazol-2-yl)-
2,5-diphenyltetrazolium bromide] and alkaline single cell gel
electrophoresis (Comet) assays, respectively. Human keratinocytes
were treated with different doses of arsenic trioxide for 4 h prior to
cytogenetic assessment. Data obtained from the MTT assay indicated
that arsenic trioxide significantly reduced the viability of HaCaT cells
in a dose-dependent manner, showing an IC50 value of 34.18 ± 0.6
μM. Data generated from the comet assay also indicated a significant
dose-dependent increase in DNA damage in HaCaT cells associated
with arsenic trioxide exposure. We observed a significant increase in
comet tail length and tail moment, showing an evidence of arsenic
trioxide -induced genotoxic damage in HaCaT cells. This study
confirms that the comet assay is a sensitive and effective method to
detect DNA damage caused by arsenic.
Abstract: This paper presents small signal stability study carried
over the 140-Bus, 31-Machine, 5-Area MEPE system and validated
on free and open source software: PSAT. Well-established linearalgebra
analysis, eigenvalue analysis, is employed to determine the
small signal dynamic behavior of test system. The aspects of local
and interarea oscillations which may affect the operation and
behavior of power system are analyzed. Eigenvalue analysis is carried
out to investigate the small signal behavior of test system and the
participation factors have been determined to identify the
participation of the states in the variation of different mode shapes.
Also, the variations in oscillatory modes are presented to observe the
damping performance of the test system.