Abstract: Numerous investigations suggest that Mesenchymal
Stem Cells (MSCs) in general represent a valuable tool for therapy of
symptoms related to chronic inflammatory diseases. Blue Horizon
Stem Cell Therapy Program is a leading provider of adult and
children’s stem cell therapies. Uniquely we have safely and
efficiently treated more than 600 patients with documenting each
procedure. The purpose of our study is primarily to monitor the
immune response in order to validate the safety of intravenous
infusion of human umbilical cord blood derived MSCs (UC-MSCs),
and secondly, to evaluate effects on biomarkers associated with
chronic inflammation. Nine patients were treated for conditions
associated with chronic inflammation and for the purpose of antiaging.
They have been given one intravenous infusion of UCMSCs.
Our study of blood test markers of 9 patients with chronic
inflammation before and within three months after MSCs treatment
demonstrates that there is no significant changes and MSCs treatment
was safe for the patients. Analysis of different indicators of chronic
inflammation and aging included in initial, 24-hours, two weeks and
three months protocols showed that stem cell treatment was safe for
the patients; there were no adverse reactions. Moreover data from
follow up protocols demonstrates significant improvement in energy
level, hair, nails growth and skin conditions. Intravenously
administered UC-MSCs were safe and effective in the improvement
of symptoms related to chronic inflammation. Further close
monitoring and inclusion of more patients are necessary to fully
characterize the advantages of UC-MSCs application in treatment of
symptoms related to chronic inflammation.
Abstract: In this paper we present a classification of the various technologies applied for the solution of the portfolio selection problem according to the discipline and the methodological framework followed. We provide a concise presentation of the emerged categories and we are trying to identify which methods considered obsolete and which lie at the heart of the debate. On top of that, we provide a comparative study of the different technologies applied for efficient portfolio construction and we suggest potential paths for future work that lie at the intersection of the presented techniques.
Abstract: This paper proposes that in the course of evolution
pitch structure became a human specific tool of communication the
function of which is to induce emotional states such as uncertainty
and cohesion. By the means of eliciting these emotions during
collective music performance people are able to unconsciously give
cues concerning social acceptance. This is probably one of the
reasons why in all cultures people collectively perform tonal music. It
is also suggested that tonal pitch structure had been invented socially
before it became an evolutionary innovation of hominines. It means
that a predisposition to tonally organize pitches evolved by the means
of ‘Baldwin effect’ – a process in which natural selection transforms
the learned response of an organism into the instinctive response. In
the proposed, hypothetical evolutionary scenario of the emergence of
tonal pitch structure social forces such as a need for closer
cooperation play the crucial role.
Abstract: Natural dyes are gaining interest due their expected
low risk to human health and to the environment. In this study, the
wash fastness of a natural coloring matter from the liquid waste
produced in the steam treatment of eucalyptus wood in textile fabrics
was investigated. Specifically, eucalyptus wood extract was used to
dye cotton, nylon and wool in an exhaust dyeing process without the
addition of the traditional mordanting agents and then submitted to
wash fastness analysis. The resulting dyed fabrics were evaluated for
color fastness. It was found that wash fastness of dyed fabrics was
very good to cotton and excellent to nylon and wool.
Abstract: This paper introduces a method to optimal design of a
hybrid Wind/Photovoltaic/Fuel cell generation system for a typical
domestic load that is not located near the electricity grid. In this
configuration the combination of a battery, an electrolyser, and a
hydrogen storage tank are used as the energy storage system. The aim
of this design is minimization of overall cost of generation scheme
over 20 years of operation. The Matlab/Simulink is applied for
choosing the appropriate structure and the optimization of system
sizing. A teaching learning based optimization is used to optimize the
cost function. An overall power management strategy is designed for
the proposed system to manage power flows among the different
energy sources and the storage unit in the system. The results have
been analyzed in terms of technical and economic. The simulation
results indicate that the proposed hybrid system would be a feasible
solution for stand-alone applications at remote locations.
Abstract: This study discusses a Turkish music education model
similar to its Venezuelan counterpart El Sistema, in which
socialization and human development are the main goals. The Music
for Peace (Baris Icin Muzik) model, founded in 2005 by an idealist
humanitarian in Istanbul, started as a pilot project with accordion and
today makes symphonic music education. The program aims to offer
social change through free-of-charge. In such a big city like Istanbul, in a deprived inner city center
people have poor economic, social and cultural conditions. In that
Edirnekapi district people don’t have opportunities to join the cultural
and social life, like music or sports. It is believed that this initiative
covered a part of this gap by giving children the opportunities to
participate in social and cultural life. In this study it is planned to understand what social changes could
music education could make in children’s lives. In the complimentary
music lessons children works in groups, which helps them to learn
the feelings of solidarity, friendship, communion and sharing. By Music for Peace project children connect with the community,
they have the belief to succeed in life because they feel that they are
loved by their friends, instructors and families. In short they feel that
they are important, thus brings the success in life. Additionally, it is
believed that, this program has achieved success. Today
approximately 400 children participate in this programs orchestras
and choirs. Some of the students get into the conservatories. And the
center is not just a place where they get music lessons but also a place
where they get socialized. And music education helps children to
have strong sense of identity, self-confidence and self-esteem.
Abstract: In this paper, relationship between different properties
of IC concrete and water cement ratio, obtained from a
comprehensive experiment conducted on IC using local materials
(Burnt clay chips- BC) is presented. In addition, saturated SAP was
used as an IC material in some cases. Relationships have been
developed through regression analysis. The focus of this analysis is
on developing relationship between a dependent variable and an
independent variable. Different percent replacements of BC and
water cement ratios were used. Compressive strength, modulus of
elasticity, water permeability and chloride permeability were tested
and variations of these parameters were analyzed with respect to
water cement ratio.
Abstract: Investigating the dynamic responses of high rise
structures under the effect of siesmic ground motion is extremely
important for the proper analysis and design of multitoried structures.
Since the presence of infilled walls strongly influences the behaviour
of frame systems in multistoried buildings, there is an increased need
for developing guidelines for the analysis and design of infilled
frames under the effect of dynamic loads for safe and proper design
of buildings. In this manuscript, we evaluate the natural frequencies
and natural periods of single bay single storey frames considering the
effect of infill walls by using the Eigen value analysis and validating
with SAP 2000 (free vibration analysis). Various parameters obtained
from the diagonal strut model followed for the free vibration analysis
is then compared with the Finite Element model, where infill is
modeled as shell elements (four noded). We also evaluated the effect
of various parameters on the natural periods of vibration obtained by
free vibration analysis in SAP 2000 comparing them with those
obtained by the empirical expressions presented in I.S. 1893(Part I)-
2002.
Abstract: Adequate analgesia following caesarean section
decreases morbidity, hastens ambulation, improves patient outcome
and facilitates care of the newborn. Intrathecal magnesium, an
NMDA antagonist, has been shown to prolong analgesia without
significant side effects in healthy parturients. The aim of this study
was to evaluate the onset and duration of sensory and motor block,
hemodynamic effect, postoperative analgesia, and adverse effects of
magnesium or fentanyl given intrathecally with hyperbaric 0.5%
bupivacaine in patients with mild preeclampsia undergoing caesarean
section. Sixty women with mild preeclampsia undergoing elective
caesarean section were included in a prospective, double blind,
controlled trial. Patients were randomly assigned to receive spinal
anesthesia with 2 mL 0.5% hyperbaric bupivacaine with 12.5 μg
fentanyl (group F) or 0.1 ml of 50% magnesium sulphate (50 mg)
(group M) with 0.15ml preservative free distilled water. Onset,
duration and recovery of sensory and motor block, time to maximum
sensory block, duration of spinal anaesthesia and postoperative
analgesic requirements were studied. Statistical comparison was
carried out using the Chi-square or Fisher’s exact tests and
Independent Student’s t-test where appropriate. The onset of both
sensory and motor block was slower in the magnesium group. The
duration of spinal anaesthesia (246 vs. 284) and motor block (186.3
vs. 210) were significantly longer in the magnesium group. Total
analgesic top up requirement was less in group M. Hemodynamic
parameters were similar in both the groups. Intrathecal magnesium
caused minimal side effects. Since Fentanyl and other opioid
congeners are not available throughout the country easily,
magnesium with its easy availability and less side effect profile can
be a cost effective alternative to fentanyl in managing pregnancy
induced hypertension (PIH) patients given along with Bupivacaine
intrathecally in caesarean section.
Abstract: In this article, a new method is proposed for the measuring of well-being inequality through a model composed of superimposing satisfaction waves. The displacement of households’ satisfactory state (i.e. satisfaction) is defined in a satisfaction string. The duration of the satisfactory state for a given period is measured in order to determine the relationship between utility and total satisfactory time, itself dependent on the density and tension of each satisfaction string. Thus, individual cardinal total satisfaction values are computed by way of a one-dimensional form for scalar sinusoidal (harmonic) moving wave function, using satisfaction waves with varying amplitudes and frequencies which allow us to measure wellbeing inequality. One advantage to using satisfaction waves is the ability to show that individual utility and consumption amounts would probably not commute; hence, it is impossible to measure or to know simultaneously the values of these observables from the dataset. Thus, we crystallize the problem by using a Heisenberg-type uncertainty resolution for self-adjoint economic operators. We propose to eliminate any estimation bias by correlating the standard deviations of selected economic operators; this is achieved by replacing the aforementioned observed uncertainties with households’ perceived uncertainties (i.e. corrected standard deviations) obtained through the logarithmic psychophysical law proposed by Weber and Fechner.
Abstract: In the present paper the design of plate heat exchangers
is formulated as an optimization problem considering two
mathematical modelling. The number of plates is the objective
function to be minimized, considering implicitly some parameters
configuration. Screening is the optimization method used to solve the
problem. Thermal and hydraulic constraints are verified, not viable
solutions are discarded and the method searches for the convergence to
the optimum, case it exists. A case study is presented to test the
applicability of the developed algorithm. Results show coherency with
the literature.
Abstract: Multiple-input multiple-output (MIMO) radar has
received increasing attention in recent years. MIMO radar has many
advantages over conventional phased array radar such as target
detection,resolution enhancement, and interference suppression. In
this paper, the results are presented from a simulation study of MIMO
uniformly-spaced linear array (ULA) antennas. The performance is
investigated under varied parameters, including varied array size,
pseudo random (PN) sequence length, number of snapshots, and
signal to noise ratio (SNR). The results of MIMO are compared to a
traditional array antenna.
Abstract: Mobile Ad Hoc Networks (MANETs) is a collection
of mobile devices forming a communication network without
infrastructure. MANET is vulnerable to security threats due to
network’s limited security, dynamic topology, scalability and the lack
of central management. The Quality of Service (QoS) routing in such
networks is limited by network breakage caused by node mobility or
nodes energy depletions. The impact of node mobility on trust
establishment is considered and its use to propagate trust through a
network is investigated in this paper. This work proposes an
enhanced Associativity Based Routing (ABR) with Fuzzy based
Trust (Fuzzy- ABR) routing protocol for MANET to improve QoS
and to mitigate network attacks.
Abstract: The increasing volume of solid waste generated,
collected and disposed daily complicate adequate management of
solid waste by relevant agency like Niger State Environmental
Protection Agency (NISEPA). In addition, the impacts of solid waste
on the natural environment and human livelihood require
identification of cost-effective ways for sustainable municipal waste
management in Nigeria. These signal the need for identifying
environment-friendly initiative and local solution to address the
problem of municipal solid waste. A research field was secured at
Pago, Minna, Niger State which is located in the guinea savanna belt
of Nigeria, within longitude 60 361 4311 - 4511 and latitude 90 291
37.6111 - .6211 N. Poultry droppings, decomposed household waste
manure and NPK treatments were used. The experimental field was
divided into three replications and four (4) treatments on each
replication making a total of twelve (12) plots. The treatments were
allotted using Randomized Complete Block Design (RCBD) and
Data collected was analyzed using SPSS software and RCBD. The
result depicts variation in plant height and number of leaves at 50%
flowering; Poultry dropping records the highest height while the
number of leaves for waste manure competes fairly well with NPK
treatment. Similarly, the varying treatments significantly increase
vegetable yield, as the control (non-treatment) records the least yield
for the three vegetable samples. Adoption of this organic manure for
cultivation does not only enhance environment quality and attainment
of food security but will contribute to local economic development,
poverty alleviation as well as social inclusion.
Abstract: This survey paper shows the recent state of model
comparison as it’s applies to Model Driven engineering. In Model
Driven Engineering to calculate the difference between the models is
a very important and challenging task. There are number of tasks
involved in model differencing that firstly starts with identifying and
matching the elements of the model. In this paper, we discuss how
model matching is accomplished, the strategies, techniques and the
types of the model. We also discuss the future direction. We found
out that many of the latest model comparison strategies are geared
near enabling Meta model and similarity based matching. Therefore
model versioning is the most dominant application of the model
comparison. Recently to work on comparison for versioning has
begun to deteriorate, giving way to different applications. Ultimately
there is wide change among the tools in the measure of client exertion
needed to perform model comparisons, as some require more push to
encourage more sweeping statement and expressive force.
Abstract: A new design of aerostatic thrust bearing is proposed
for high static stiffness. The bearing body, which is mead of polymer
covered with metallic membrane, is held by a circular ring. Such a
support helps form a concave air gap to grasp the air pressure. The
polymer body, which can be made rapidly by either injection or
molding is able to provide extra damping under dynamic loading. The
smooth membrane not only serves as the bearing surface but also
protects the polymer body. The restrictor is a capillary inside a silicone
tube. It can passively compensate the variation of load by expanding
the capillary diameter for more air flux. In the present example, the
stiffness soars from 15.85 N/μm of typical bearing to 349.85 N/μm at
bearing elevation 9.5 μm; meanwhile the load capacity also enhances
from 346.86 N to 704.18 N.
Abstract: Concrete is strong in compression however weak in
tension. The tensile strength as well as ductile property of concrete
could be improved by addition of short dispersed fibers. Polyethylene
terephthalate (PET) fiber obtained from hand cutting or mechanical
slitting of plastic sheets generally used as discrete reinforcement in
substitution of steel fiber. PET fiber obtained from the former process
is in the form of straight slit sheet pattern that impart weaker
mechanical bonding behavior in the concrete matrix. To improve the
limitation of straight slit sheet fiber the present study considered two
additional geometry of fiber namely (a) flattened end slit sheet and
(b) deformed slit sheet. The mix for plain concrete was design for a
compressive strength of 25 MPa at 28 days curing time with a watercement
ratio of 0.5. Cylindrical and beam specimens with 0.5% fibers
volume fraction and without fibers were cast to investigate the
influence of geometry on the mechanical properties of concrete. The
performance parameters mainly studied include flexural strength,
splitting tensile strength, compressive strength and ultrasonic pulse
velocity (UPV). Test results show that geometry of fiber has a
marginal effect on the workability of concrete. However, it plays a
significant role in achieving a good compressive and tensile strength
of concrete. Further, significant improvement in term of flexural and
energy dissipation capacity were observed from other fibers as
compared to the straight slit sheet pattern. Also, the inclusion of PET
fiber improved the ability in absorbing energy in the post-cracking
state of the specimen as well as no significant porous structures.
Abstract: The goal of the modern education system is to prepare
students to be able to adapt to ever-changing life situations. They
must be able to acquire required knowledge independently; apply
such knowledge in practice to solve various problems by using
modern technologies; think critically and creatively; competently use
information; be communicative, work in a team; and develop their
own moral values, intellect and cultural awareness. As a result, the
status of education significantly increases; new requirements to its
quality have been formed. In recent years the competency-based
approach in education has become of significant interest. This
approach is a strengthening of applied and practical characteristics of
a school education and leads to the forming of the key students’
competencies which define their success in future life. In this article,
the authors’ attention focuses on a range of key competencies,
educational, informational and communicative and on the possibility
to develop such competencies via STEM education. This research
shows the change in students’ attitude towards scientific disciplines
such as mathematics, general science, technology and engineering as
a result of STEM education. Two staged analyzed questionnaires
completed by students of forms II to IV in the republic of Trinidad
and Tobago allowed the authors to categorize students between two
levels that represent students’ attitude to various disciplines. The
significance of differences between selected levels was confirmed
with the use of Pearson’s chi-squared test. In summary, the analysis
of obtained data makes it possible to conclude that STEM education
has a great potential for development of core students’ competencies
and encourage the development of positive student attitude towards
the above mentioned above scientific disciplines.
Abstract: This paper seeks to assess the implications of
insurance to foreign direct investment inflow in Nigeria. Multiple
linear regression technique and correlation matrix test were employed
to measure the extent to which foreign direct investment was
influenced. The result showed that insurance premium (IP), asset size
of insurance industry (AS), and total investment of the industry (TI)
impacted significantly and positively on foreign direct investment
inflow in Nigeria. There should be effective risk transfer mechanism
and financial intermediation, which gives the investor confidence in
the risk management strength of the host country.
Abstract: Information technology plays an irreplaceable role in
introducing and improving business process orientation in a
company. It enables implementation of the theoretical concept,
measurement of results achieved and undertaking corrective
measures aimed at improvements. Information technology is a key
concept in the development and implementation of the business
process management systems as it establishes a connection to
business operations. Both in the literature and practice, insurance
companies are often seen as highly process oriented due to the nature
of their business and focus on customers. They are also considered
leaders in using information technology for business process
management. The research conducted aimed to investigate whether
the perceived leadership status of insurance companies is well
deserved, i.e. to establish the level of process orientation and explore
the practice of information technology use in insurance companies in
the region. The main instrument for primary data collection within
this research was an electronic survey questionnaire sent to the
management of insurance companies in the Republic of Croatia,
Bosnia and Herzegovina, Slovenia, Serbia and Macedonia. The
conducted research has shown that insurance companies have a
satisfactory level of process orientation, but that there is also a huge
potential for improvement, especially in the segment of information
technology and its connection to business processes.