Abstract: To identify an endothelial cell-specific promoter suitable for vascular-specific targeting, we tested five promoters in vitro--Tie2SE, Tie2LE, ICAM2, Flt-1 and vWF--for promoter activity and specificity in endothelial cells, smooth muscle cells and non-vascular resident cells as well as tissues. These promoters, except for vWF, exhibited good endothelial activity and specificity in vitro. In a syngenic heart transplantation model, the ICAM2 promoter was variably functional in coronary endothelial cells of donor hearts. Thus, the ICAM2, Flt-1, Tie2SE and Tie2LE promoters hold promise for endothelial-specific targeting, but in vitro expression may not predict in vivo expression.
Abstract: In this study we present our developed formative
assessment tool for students' assignments. The tool enables lecturers
to define assignments for the course and assign each problem in each
assignment a list of criteria and weights by which the students' work
is evaluated. During assessment, the lecturers feed the scores for each
criterion with justifications. When the scores of the current
assignment are completely fed in, the tool automatically generates
reports for both students and lecturers. The students receive a report
by email including detailed description of their assessed work, their
relative score and their progress across the criteria along the course
timeline. This information is presented via charts generated
automatically by the tool based on the scores fed in. The lecturers
receive a report that includes summative (e.g., averages, standard
deviations) and detailed (e.g., histogram) data of the current
assignment. This information enables the lecturers to follow the class
achievements and adjust the learning process accordingly. The tool
was examined on two pilot groups of college students that study a
course in (1) Object-Oriented Programming (2) Plane Geometry.
Results reveal that most of the students were satisfied with the
assessment process and the reports produced by the tool. The
lecturers who used the tool were also satisfied with the reports and
their contribution to the learning process.
Abstract: Adhesively bonded joints are preferred over the
conventional methods of joining such as riveting, welding, bolting
and soldering. Some of the main advantages of adhesive joints
compared to conventional joints are the ability to join dissimilar
materials and damage-sensitive materials, better stress distribution,
weight reduction, fabrication of complicated shapes, excellent
thermal and insulation properties, vibration response and enhanced
damping control, smoother aerodynamic surfaces and an
improvement in corrosion and fatigue resistance. This paper presents
the behavior of adhesively bonded joints subjected to combined
thermal loadings, using the numerical methods. The joint
configuration considers aluminum as central adherend with six
different outer adherends including aluminum, steel, titanium, boronepoxy,
unidirectional graphite-epoxy and cross-ply graphite-epoxy
and epoxy-based adhesives. Free expansion of the joint in x
direction was permitted and stresses in adhesive layer and interfaces
calculated for different adherends.
Abstract: A new multi inner stage (MIS) cyclone was designed to
remove the acidic gas and fine particles produced from electronic
industry. To characterize gas flow in MIS cyclone, pressure and
velocity distribution were calculated by means of CFD program. Also,
the flow locus of fine particles and particle removal efficiency were
analyzed by Lagrangian method. When outlet pressure condition was
–100mmAq, the efficiency was the best in this study.
Abstract: Prediction of bacterial virulent protein sequences can
give assistance to identification and characterization of novel
virulence-associated factors and discover drug/vaccine targets against
proteins indispensable to pathogenicity. Gene Ontology (GO)
annotation which describes functions of genes and gene products as a
controlled vocabulary of terms has been shown effectively for a
variety of tasks such as gene expression study, GO annotation
prediction, protein subcellular localization, etc. In this study, we
propose a sequence-based method Virulent-GO by mining informative
GO terms as features for predicting bacterial virulent proteins.
Each protein in the datasets used by the existing method
VirulentPred is annotated by using BLAST to obtain its homologies
with known accession numbers for retrieving GO terms. After
investigating various popular classifiers using the same five-fold
cross-validation scheme, Virulent-GO using the single kind of GO
term features with an accuracy of 82.5% is slightly better than
VirulentPred with 81.8% using five kinds of sequence-based features.
For the evaluation of independent test, Virulent-GO also yields better
results (82.0%) than VirulentPred (80.7%). When evaluating single
kind of feature with SVM, the GO term feature performs much well,
compared with each of the five kinds of features.
Abstract: Emergence of smartphones brings to live the concept
of converged devices with the availability of web amenities. Such
trend also challenges the mobile devices manufactures and service
providers in many aspects, such as security on mobile phones,
complex and long time design flow, as well as higher development
cost. Among these aspects, security on mobile phones is getting more
and more attention. Microkernel based virtualization technology will
play a critical role in addressing these challenges and meeting mobile
market needs and preferences, since virtualization provides essential
isolation for security reasons and it allows multiple operating systems
to run on one processor accelerating development and cutting development
cost. However, virtualization benefits do not come for free.
As an additional software layer, it adds some inevitable virtualization
overhead to the system, which may decrease the system performance.
In this paper we evaluate and analyze the virtualization performance
cost of L4 microkernel based virtualization on a competitive mobile
phone by comparing the L4Linux, a para-virtualized Linux on top of
L4 microkernel, with the native Linux performance using lmbench
and a set of typical mobile phone applications.
Abstract: Zero inflated strict arcsine model is a newly developed
model which is found to be appropriate in modeling overdispersed
count data. In this study, we extend zero inflated strict arcsine model
to zero inflated strict arcsine regression model by taking into
consideration the extra variability caused by extra zeros and
covariates in count data. Maximum likelihood estimation method is
used in estimating the parameters for this zero inflated strict arcsine
regression model.
Abstract: The term private equity usually refers to any type of
equity investment in an asset in which the equity is not freely
tradable on a public stock market. Some researchers believe that
private equity contributed to the extent of the crisis and increased
the pace of its spread over the world. We do not agree with this.
On the other hand, we argue that during the economic recession
private equity might become an important source of funds for firms
with special needs (e.g. for firms seeking buyout financing, venture
capital, expansion capital or distress debt financing). However,
over-regulation of private equity in both the European Union and
the US can slow down this specific funding channel to the
economy and deepen credit crunch during global crises.
Abstract: The last Assessment Report of the Intergovernmental
Panel on Climate Change, stating that the greatest risk in climate
change affects sustainability is now widely known and accepted.
However, it has not provoked substantial reaction and attention in
Hungary, while international and national efforts have also not
achieved expected results so far. Still, there are numerous examples
on different levels (national, regional, local, household) making
considerable progress in limiting their own emissions and making
steps toward mitigation of and adaptation to climate change. The
local level is exceptionally important in sustainability adaptation, as
local communities are often able to adapt more flexibly to changes in
the natural environment.The aim of this paper is to attempt a review
of the national climate policy and the local climate change strategies
in Hungary considering sustainable development.
Abstract: This study proposes a conceptual model and
empirically tests the relationships between customers and librarians
(i.e. tangibles, responsiveness, assurance, reliability and empathy)
with a dependent variable (customer satisfaction) regarding library
services. The SERVQUAL instrument was administered to 100
respondents which comprises of staff and students at a public higher
learning institution in the Federal Territory of Labuan, Malaysia.
They were public university library users. Results revealed that all
service quality dimensions tested were significant and influenced
customer satisfaction of visitors to a public university library.
Assurance is the most important factor that influences customer
satisfaction with the services rendered by the librarian. It is
imperative for the library management to take note that the top five
service attributes that gained greatest attention from library visitors-
perspective includes employee willingness to help customers,
availability of customer representatives online for response to
queries, library staff actively and promptly provide services, signs in
the building are clear and library staff are friendly and courteous.
This study provides valuable results concerning the determinants of
the service quality and customer satisfaction of public university
library services from the users' perspective.
Abstract: Multiphase flow transport in porous medium is very common and significant in science and engineering applications. For example, in CO2 Storage and Enhanced Oil Recovery processes, CO2 has to be delivered to the pore spaces in reservoirs and aquifers. CO2 storage and enhance oil recovery are actually displacement processes, in which oil or water is displaced by CO2. This displacement is controlled by pore size, chemical and physical properties of pore surfaces and fluids, and also pore wettability. In this study, a technique was developed to measure the pressure profile for driving gas/liquid to displace water in pores. Through this pressure profile, the impact of pore size on the multiphase flow transport and displacement can be analyzed. The other rig developed can be used to measure the static and dynamic pore wettability and investigate the effects of pore size, surface tension, viscosity and chemical structure of liquids on pore wettability.
Abstract: The response surface methodology (RSM) is a
collection of mathematical and statistical techniques useful in the
modeling and analysis of problems in which the dependent variable
receives the influence of several independent variables, in order to
determine which are the conditions under which should operate these
variables to optimize a production process. The RSM estimated a
regression model of first order, and sets the search direction using the
method of maximum / minimum slope up / down MMS U/D.
However, this method selects the step size intuitively, which can
affect the efficiency of the RSM. This paper assesses how the step
size affects the efficiency of this methodology. The numerical
examples are carried out through Monte Carlo experiments,
evaluating three response variables: efficiency gain function, the
optimum distance and the number of iterations. The results in the
simulation experiments showed that in response variables efficiency
and gain function at the optimum distance were not affected by the
step size, while the number of iterations is found that the efficiency if
it is affected by the size of the step and function type of test used.
Abstract: Non-saturated soils that while saturation greatly
decrease their volume, have sudden settlement due to increasing
humidity, fracture and structural crack are called loess soils. Whereas
importance of civil projects including: dams, canals and
constructions bearing this type of soil and thereof problems, it is
required for carrying out more research and study in relation to loess
soils. This research studies shear strength parameters by using
grading test, Atterberg limit, compression, direct shear and
consolidation and then effect of using cement and lime additives on
stability of loess soils is studied. In related tests, lime and cement are
separately added to mixed ratios under different percentages of soil
and for different times the stabilized samples are processed and effect
of aforesaid additives on shear strength parameters of soil is studied.
Results show that upon passing time the effect of additives and
collapsible potential is greatly decreased and upon increasing
percentage of cement and lime the maximum dry density is
decreased; however, optimum humidity is increased. In addition,
liquid limit and plastic index is decreased; however, plastic index
limit is increased. It is to be noted that results of direct shear test
reveal increasing shear strength of soil due to increasing cohesion
parameter and soil friction angle.
Abstract: The aim of this paper to characterize a larger set of
wavelet functions for implementation in a still image compression
system using SPIHT algorithm. This paper discusses important
features of wavelet functions and filters used in sub band coding to
convert image into wavelet coefficients in MATLAB. Image quality
is measured objectively using peak signal to noise ratio (PSNR) and
its variation with bit rate (bpp). The effect of different parameters is
studied on different wavelet functions. Our results provide a good
reference for application designers of wavelet based coder.
Abstract: This research was carried out to determine the
possible effects of low electromagnetic field (EMF) exposure to the
developing mice fetuses. Pregnant mice were exposed to EMF
exposure at 0mT (sham) and 1.2 mT for six hours per session, carried
out on gestation day 3, 6, 9, 12 and 15. Samples from the stillborn
offspring were observed for morphological defects. The heart didn-t
show progressive cellular damage, the lungs were congested and
emphysemics. The bones were in advance stage of hypertrophy.
Spectrums of morphological defects were observed over 70% of the
surviving offspring. These results indicate that even at lower
exposure to low EMF, is enough to induce morphological defects in
prenatal mice.
Abstract: The world-s largest Pre-stressed Concrete Cylinder
Pipe (PCCP) water supply project had a series of pipe failures which
occurred between 1999 and 2001. This has led the Man-Made River
Authority (MMRA), the authority in charge of the implementation
and operation of the project, to setup a rehabilitation plan for the
conveyance system while maintaining the uninterrupted flow of
water to consumers. At the same time, MMRA recognized the need
for a long term management tool that would facilitate repair and
maintenance decisions and enable taking the appropriate preventive
measures through continuous monitoring and estimation of the
remaining life of each pipe. This management tool is known as the
Pipe Risk Management System (PRMS) and now in operation at
MMRA. Both the rehabilitation plan and the PRMS require the
availability of complete and accurate pipe construction and
manufacturing data
This paper describes a systematic approach of data collection,
analysis, evaluation and correction for the construction and
manufacturing data files of phase I pipes which are the platform for
the PRMS database and any other related decision support system.
Abstract: Octree compression techniques have been used
for several years for compressing large three dimensional data
sets into homogeneous regions. This compression technique
is ideally suited to datasets which have similar values in
clusters. Oil engineers represent reservoirs as a three dimensional
grid where hydrocarbons occur naturally in clusters. This
research looks at the efficiency of storing these grids using
octree compression techniques where grid cells are broken
into active and inactive regions. Initial experiments yielded
high compression ratios as only active leaf nodes and their
ancestor, header nodes are stored as a bitstream to file on
disk. Savings in computational time and memory were possible
at decompression, as only active leaf nodes are sent to the
graphics card eliminating the need of reconstructing the original
matrix. This results in a more compact vertex table, which can
be loaded into the graphics card quicker and generating shorter
refresh delay times.
Abstract: The paper presents the potential of fuzzy logic (FL-I)
and neural network techniques (ANN-I) for predicting the
compressive strength, for SCC mixtures. Six input parameters that is
contents of cement, sand, coarse aggregate, fly ash, superplasticizer
percentage and water-to-binder ratio and an output parameter i.e. 28-
day compressive strength for ANN-I and FL-I are used for modeling.
The fuzzy logic model showed better performance than neural
network model.
Abstract: Power cables are vulnerable to failure due to aging or
defects that occur with the passage of time under continuous
operation and loading stresses. PD detection and characterization
provide information on the location, nature, form and extent of the
degradation. As a result, PD monitoring has become an important
part of condition based maintenance (CBM) program among power
utilities. Online partial discharge (PD) localization of defect sources
in power cable system is possible using the time of flight method.
The information regarding the time difference between the main and
reflected pulses and cable length can help in locating the partial
discharge source along the cable length. However, if the length of
the cable is not known and the defect source is located at the extreme
ends of the cable or in the middle of the cable, then double ended
measurement is required to indicate the location of PD source. Use of
multiple sensors can also help in discriminating the cable PD or local/
external PD. This paper presents the experience and results from
online partial discharge measurements conducted in the laboratory
and the challenges in partial discharge source localization.
Abstract: Chicken fat was employed as a feedstock for
producing of biodiesel by trasesterification reaction with methanol
and alkali catalyst (KOH). In this study chicken fat biodiesel with
1.4% free fatty acid, methanol and various amount of potassium
hydroxide for 2 hour were studied. The progression of reaction and
conversion of triglycerides to methyl ester were checked by IR
spectrum method.