Abstract: The objective of this manuscript is to find area under the plasma concentration- time curve (AUC) for multiple doses of salbutamol sulphate sustained release tablets (Ventolin® oral tablets SR 8 mg, GSK, Pakistan) in the group of 18 healthy adults by using computational mathematics techniques. Following the administration of 4 doses of Ventolin® tablets 12 hourly to 24 healthy human subjects and bioanalysis of obtained plasma samples, plasma drug concentration-time profile was constructed. AUC, an important pharmacokinetic parameter, was measured using integrated equation of multiple oral dose regimens. The approximated AUC was also calculated by using computational mathematics techniques such as repeated rectangular, repeated trapezium and repeated Simpson's rule and compared with exact value of AUC calculated by using integrated equation of multiple oral dose regimens to find best computational mathematics method that gives AUC values closest to exact. The exact values of AUC for four consecutive doses of Ventolin® oral tablets were 150.5819473, 157.8131756, 164.4178231 and 162.78 ng.h/ml while the closest values approximated AUC values were 149.245962, 157.336171, 164.2585768 and 162.289224 ng.h/ml, respectively as found by repeated rectangular rule. The errors in the approximated values of AUC were negligible. It is concluded that all computational tools approximated values of AUC accurately but the repeated rectangular rule gives slightly better approximated values of AUC as compared to repeated trapezium and repeated Simpson's rules.
Abstract: Nowadays companies strive to survive in a
competitive global environment. To speed up product
development/modifications, it is suggested to adopt a collaborative
product development approach. However, despite the advantages of
new IT improvements still many CAx systems work separately and
locally. Collaborative design and manufacture requires a product
information model that supports related CAx product data models. To
solve this problem many solutions are proposed, which the most
successful one is adopting the STEP standard as a product data model
to develop a collaborative CAx platform. However, the improvement
of the STEP-s Application Protocols (APs) over the time, huge
number of STEP AP-s and cc-s, the high costs of implementation,
costly process for conversion of older CAx software files to the STEP
neutral file format; and lack of STEP knowledge, that usually slows
down the implementation of the STEP standard in collaborative data
exchange, management and integration should be considered. In this
paper the requirements for a successful collaborative CAx system is
discussed. The STEP standard capability for product data integration
and its shortcomings as well as the dominant platforms for supporting
CAx collaboration management and product data integration are
reviewed. Finally a platform named LAYMOD to fulfil the
requirements of CAx collaborative environment and integrating the
product data is proposed. The platform is a layered platform to enable
global collaboration among different CAx software
packages/developers. It also adopts the STEP modular architecture
and the XML data structures to enable collaboration between CAx
software packages as well as overcoming the STEP standard
limitations. The architecture and procedures of LAYMOD platform
to manage collaboration and avoid contradicts in product data
integration are introduced.
Abstract: terrorism and extremism are among the most
dangerous and difficult to forecast the phenomena of our time, which
are becoming more diverse forms and rampant. Terrorist attacks often
produce mass casualties, involve the destruction of material and
spiritual values, beyond the recovery times, sow hatred among
nations, provoke war, mistrust and hatred between the social and
national groups, which sometimes can not be overcome within a
generation. Currently, the countries of Central Asia are a topical issue
– the threat of terrorism and religious extremism, which grow not
only in our area, but throughout the world. Of course, in each of the
terrorist threat is assessed differently. In our country the problem of
terrorism should not be acutely. Thus, after independence and
sovereignty of Kazakhstan has chosen the path of democracy,
progress and free economy. With the policy of the President of
Kazakhstan Nursultan Nazarbayev and well-organized political and
economic reforms, there has been economic growth and rising living
standards, socio-political stability, ensured civil peace and accord in
society [1].
Abstract: In the gas refineries of Iran-s South Pars Gas
Complex, Sulfrex demercaptanization process is used to remove
volatile and corrosive mercaptans from liquefied petroleum gases by
caustic solution. This process consists of two steps. Removing low
molecular weight mercaptans and regeneration exhaust caustic. Some
parameters such as LPG feed temperature, caustic concentration and
feed-s mercaptan in extraction step and sodium mercaptide content in
caustic, catalyst concentration, caustic temperature, air injection rate
in regeneration step are effective factors. In this paper was focused on
temperature factor that play key role in mercaptans extraction and
caustic regeneration. The experimental results demonstrated by
optimization of temperature, sodium mercaptide content in caustic
because of good oxidation minimized and sulfur impurities in
product reduced.
Abstract: Field Association (FA) terms are a limited set of discriminating terms that give us the knowledge to identify document fields which are effective in document classification, similar file retrieval and passage retrieval. But the problem lies in the lack of an effective method to extract automatically relevant Arabic FA Terms to build a comprehensive dictionary. Moreover, all previous studies are based on FA terms in English and Japanese, and the extension of FA terms to other language such Arabic could be definitely strengthen further researches. This paper presents a new method to extract, Arabic FA Terms from domain-specific corpora using part-of-speech (POS) pattern rules and corpora comparison. Experimental evaluation is carried out for 14 different fields using 251 MB of domain-specific corpora obtained from Arabic Wikipedia dumps and Alhyah news selected average of 2,825 FA Terms (single and compound) per field. From the experimental results, recall and precision are 84% and 79% respectively. Therefore, this method selects higher number of relevant Arabic FA Terms at high precision and recall.
Abstract: The response of King Abdulla Canal (KAC) water to the upgrade of As Samra Wastewater Treatment Plant which discharges its effluent to the Zarqa River is investigated. Time series quality data that extends between October 2005 and December 2009 obtained by a state of the art telemetric monitoring system were analyzed for COD, EC, TP and TN at two monitoring stations located upstream and downstream of the confluence of the Zarqa River with KAC. The samples- means and the t-test showed that there has been significant improvement in the quality of the KAC water for COD, and TP. However, the improvement in the TN was found statistically insignificant, whereas the EC of the KAC was unaffected by the upgrade. Comparing the selected parameters with the standards and guidelines for using treated wastewater in irrigation showed that the KAC water has improved towards meeting the required standards and guidelines for treated wastewater reuse in irrigation.
Abstract: Hydrodynamic pressures acting on upstream of concrete dams during an earthquake are an important factor in designing and assessing the safety of these structures in Earthquake regions. Due to inherent complexities, assessing exact hydrodynamic pressure is only feasible for problems with simple geometry. In this research, the governing equation of concrete gravity dam reservoirs with effect of fluid viscosity in frequency domain is solved and then compared with that in which viscosity is assumed zero. The results show that viscosity influences the reservoir-s natural frequency. In excitation frequencies near the reservoir's natural frequencies, hydrodynamic pressure has a considerable difference in compare to the results of non-viscose fluid.
Abstract: Mobile robots are used in a large field of scenarios,
like exploring contaminated areas, repairing oil rigs under water,
finding survivors in collapsed buildings, etc. Currently, there is no
unified intuitive user interface (UI) to control such complex mobile
robots. As a consequence, some scenarios are done without the
exploitation of experience and intuition of human teleoperators.
A novel framework has been developed to embed a flexible and
modular UI into a complete 3-D virtual reality simulation system.
This new approach wants to access maximum benefits of human
operators. Sensor information received from the robot is prepared for
an intuitive visualization. Virtual reality metaphors support the
operator in his decisions. These metaphors are integrated into a real
time stereo video stream. This approach is not restricted to any
specific type of mobile robot and allows for the operation of different
robot types with a consistent concept and user interface.
Abstract: A proposed small-signal model parameters for a pseudomorphic high electron mobility transistor (PHEMT) is presented. Both extrinsic and intrinsic circuit elements of a smallsignal model are determined using genetic algorithm (GA) as a stochastic global search and optimization tool. The parameters extraction of the small-signal model is performed on 200-μm gate width AlGaAs/InGaAs PHEMT. The equivalent circuit elements for a proposed 18 elements model are determined directly from the measured S- parameters. The GA is used to extract the parameters of the proposed small-signal model from 0.5 up to 18 GHz.
Abstract: This paper presents a robust vehicle detection approach using Haar-like feature. It is possible to get a strong edge feature from this Haar-like feature. Therefore it is very effective to remove the shadow of a vehicle on the road. And we can detect the boundary of vehicles accurately. In the paper, the vehicle detection algorithm can be divided into two main steps. One is hypothesis generation, and the other is hypothesis verification. In the first step, it determines vehicle candidates using features such as a shadow, intensity, and vertical edge. And in the second step, it determines whether the candidate is a vehicle or not by using the symmetry of vehicle edge features. In this research, we can get the detection rate over 15 frames per second on our embedded system.
Abstract: Studies revealing the positive relationship between
trade and income are often criticized with the argument that
“development should mean more than rising incomes". Taking this
argument as a base and utilizing panel data, Davies and Quinlivan [1]
have demonstrated that increases in trade are positively associated
with future increases in social welfare as measured by the Human
Development Index (HDI). The purpose of this study is twofold:
Firstly, utilizing an income based country classification; it is aimed
to investigate whether the positive association between foreign trade
and HDI is valid within all country groups. Secondly, keeping the
same categorization as a base; it is aimed to reveal whether the
positive link between trade and HDI still exists when the income
components of the index are excluded. Employing a panel data
framework of 106 countries, this study reveals that the positive link
between trade and human development is valid only for high and
medium income countries. Moreover, the positive link between trade
and human development diminishes in lower-medium income
countries when only non-income components of the index are taken
into consideration.
Abstract: Image compression is one of the most important
applications Digital Image Processing. Advanced medical imaging
requires storage of large quantities of digitized clinical data. Due to
the constrained bandwidth and storage capacity, however, a medical
image must be compressed before transmission and storage. There
are two types of compression methods, lossless and lossy. In Lossless
compression method the original image is retrieved without any
distortion. In lossy compression method, the reconstructed images
contain some distortion. Direct Cosine Transform (DCT) and Fractal
Image Compression (FIC) are types of lossy compression methods.
This work shows that lossy compression methods can be chosen for
medical image compression without significant degradation of the
image quality. In this work DCT and Fractal Compression using
Partitioned Iterated Function Systems (PIFS) are applied on different
modalities of images like CT Scan, Ultrasound, Angiogram, X-ray
and mammogram. Approximately 20 images are considered in each
modality and the average values of compression ratio and Peak
Signal to Noise Ratio (PSNR) are computed and studied. The quality
of the reconstructed image is arrived by the PSNR values. Based on
the results it can be concluded that the DCT has higher PSNR values
and FIC has higher compression ratio. Hence in medical image
compression, DCT can be used wherever picture quality is preferred
and FIC is used wherever compression of images for storage and
transmission is the priority, without loosing picture quality
diagnostically.
Abstract: This paper presents a new heuristic algorithm for the classical symmetric traveling salesman problem (TSP). The idea of the algorithm is to cut a TSP tour into overlapped blocks and then each block is improved separately. It is conjectured that the chance of improving a good solution by moving a node to a position far away from its original one is small. By doing intensive search in each block, it is possible to further improve a TSP tour that cannot be improved by other local search methods. To test the performance of the proposed algorithm, computational experiments are carried out based on benchmark problem instances. The computational results show that algorithm proposed in this paper is efficient for solving the TSPs.
Abstract: Now a days, a significant part of commercial and governmental organisations like museums, cultural organizations, libraries, commercial enterprises, etc. invest intensively in new technologies for image digitization, digital libraries, image archiving and retrieval. Hence image authorization, authentication and security has become prime need. In this paper, we present a semi-fragile watermarking scheme for color images. The method converts the host image into YIQ color space followed by application of orthogonal dual domains of DCT and DWT transforms. The DCT helps to separate relevant from irrelevant image content to generate silent image features. DWT has excellent spatial localisation to help aid in spatial tamper characterisation. Thus image adaptive watermark is generated based of image features which allows the sharp detection of microscopic changes to locate modifications in the image. Further, the scheme utilises the multipurpose watermark consisting of soft authenticator watermark and chrominance watermark. Which has been proved fragile to some predefined processing like intentinal fabrication of the image or forgery and robust to other incidental attacks caused in the communication channel.
Abstract: Economic freedoms, most emphasized issue in the recent years, are considered to affect economic growth and performance via institutional structure. In this context, a model that includes Turkey and Middle East Countries, and where the effects of economic freedom on growth are examined, was formed. For the groups of countries determined, in the study carried out by using the dataset belonging the period of 2004 - 2009, between economic freedoms and growth, a negative relationship was observed as group. In the sense of individual effects, it was identified that there was a positive relationship in terms of some Middle East Countries and Turkey.
Abstract: The aim of this study was to establish the relationship between the principles of Educational Sport and the objectives of Physical Education in two brasilian laws: National Curriculum Guidelines (PCNs) for the Elementary and Middle School Levels and the Guidelines and Basis Legislation (LDB). The method used was the survey analysis in order to determine the practices present in, or the opinions of, a specific population. The instrument used in this research was a questionnaire. After a broad review of the bibliography and according to the methodological procedures, the aim was to set the relationships between the Principles of Educational Sport and the objectives of Physical Education, according to the Brazilian Law (LDB) and National Curriculum Guidelines (PCNs) in a table made under the analysis of a group of specialists. As the relation between the principles of Educational Sport and the objectives of School Physical Education have shown, we can state that School Physical Education has gained pedagogical security for the potential use of Educational Sport as part of its contents.
Abstract: Multiple criteria decision making (MCDM) is an approach to ranking the solutions and finding the best one when two or more solutions are provided. In this study, MCDM approach is proposed to select the most suitable scheduling rule of robotic flexible assembly cells (RFACs). Two MCDM approaches, Analytic Hierarchy Process (AHP) and Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) are proposed for solving the scheduling rule selection problem. The AHP method is employed to determine the weights of the evaluation criteria, while the TOPSIS method is employed to obtain final ranking order of scheduling rules. Four criteria are used to evaluate the scheduling rules. Also, four scheduling policies of RFAC are examined to choose the most appropriate one for this purpose. A numerical example illustrates applications of the suggested methodology. The results show that the methodology is practical and works in RFAC settings.
Abstract: In this paper, a multi-branch power line is modeled using ABCD matrix to show its worth as a communication channel. The model is simulated using MATLAB in an effort to investigate the effects of multiple loading, multipath, and those as a result of load mismatching. The channel transfer function is obtained and investigated using different cable lengths, and different number of bridge taps under given loading conditions.
Abstract: Let S be an ordered semigroup. In this paper we first introduce the concepts of (∈,∈ ∨q)-fuzzy ideals, (∈,∈ ∨q)-fuzzy bi-ideals and (∈,∈ ∨q)-fuzzy generalized bi-ideals of an ordered semigroup S, and investigate their related properties. Furthermore, we also define the upper and lower parts of fuzzy subsets of an ordered semigroup S, and investigate the properties of (∈,∈ ∨q)-fuzzy ideals of S. Finally, characterizations of regular ordered semigroups and intra-regular ordered semigroups by means of the lower part of (∈ ,∈ ∨q)-fuzzy left ideals, (∈,∈ ∨q)-fuzzy right ideals and (∈,∈ ∨q)- fuzzy (generalized) bi-ideals are given.
Abstract: Saturated hydraulic conductivity is one of the soil
hydraulic properties which is widely used in environmental studies
especially subsurface ground water. Since, its direct measurement is
time consuming and therefore costly, indirect methods such as
pedotransfer functions have been developed based on multiple linear
regression equations and neural networks model in order to estimate
saturated hydraulic conductivity from readily available soil
properties e.g. sand, silt, and clay contents, bulk density, and organic
matter. The objective of this study was to develop neural networks
(NNs) model to estimate saturated hydraulic conductivity from
available parameters such as sand and clay contents, bulk density,
van Genuchten retention model parameters (i.e. r
θ , α , and n) as well
as effective porosity. We used two methods to calculate effective
porosity: : (1) eff s FC φ =θ -θ , and (2) inf φ =θ -θ eff s , in which s
θ is
saturated water content, FC θ is water content retained at -33 kPa
matric potential, and inf θ is water content at the inflection point.
Total of 311 soil samples from the UNSODA database was divided
into three groups as 187 for the training, 62 for the validation (to
avoid over training), and 62 for the test of NNs model. A commercial
neural network toolbox of MATLAB software with a multi-layer
perceptron model and back propagation algorithm were used for the
training procedure. The statistical parameters such as correlation
coefficient (R2), and mean square error (MSE) were also used to
evaluate the developed NNs model. The best number of neurons in
the middle layer of NNs model for methods (1) and (2) were
calculated 44 and 6, respectively. The R2 and MSE values of the test
phase were determined for method (1), 0.94 and 0.0016, and for
method (2), 0.98 and 0.00065, respectively, which shows that method
(2) estimates saturated hydraulic conductivity better than method (1).