Abstract: A systems approach model for prostate cancer in prostate duct, as a sub-system of the organism is developed. It is accomplished in two steps. First this research work starts with a nonlinear system of coupled Fokker-Plank equations which models continuous process of the system like motion of cells. Then extended to PDEs that include discontinuous processes like cell mutations, proliferation and deaths. The discontinuous processes is modeled by using intensity poisson processes. The model incorporates the features of the prostate duct. The system of PDEs spatial coordinate is along the proximal distal axis. Its parameters depend on features of the prostate duct. The movement of cells is biased towards distal region and mutations of prostate cancer cells is localized in the proximal region. Numerical solutions of the full system of equations are provided, and are exhibit traveling wave fronts phenomena. This motivates the use of the standard transformation to derive a canonically related system of ODEs for traveling wave solutions. The results obtained show persistence of prostate cancer by showing that the non-negative cone for the traveling wave system is time invariant. The traveling waves have a unique global attractor is proved also. Biologically, the global attractor verifies that evolution of prostate cancer stem cells exhibit the avascular tumor growth. These numerical solutions show that altering prostate stem cell movement or mutation of prostate cancer cells lead to avascular tumor. Conclusion with comments on clinical implications of the model is discussed.
Abstract: The spiral angle of the elementary cellulose fibril in
the wood cell wall, often called microfibril angle, (MFA). Microfibril
angle in hardwood is one of the key determinants of solid timber
performance due to its strong influence on the stiffness, strength,
shrinkage, swelling, thermal-dynamics mechanical properties and
dimensional stability of wood. Variation of MFA (degree) in the S2
layer of the cell walls among Acacia mangium trees was determined
using small-angle X-ray scattering (SAXS). The length and
orientation of the microfibrils of the cell walls in the irradiated
volume of the thin samples are measured using SAXS and optical
microscope for 3D surface measurement. The undetermined
parameters in the analysis are the MFA, (M) and the standard
deviation (σФ) of the intensity distribution arising from the wandering
of the fibril orientation about the mean value. Nine separate pairs of
values are determined for nine different values of the angle of the
incidence of the X-ray beam relative to the normal to the radial
direction in the sample. The results show good agreement. The
curve distribution of scattered intensity for the real cell wall structure
is compared with that calculated with that assembly of rectangular
cells with the same ratio of transverse to radial cell wall length. It is
demonstrated that for β = 45°, the peaks in the curve intensity
distribution for the real and the rectangular cells coincide. If this
peak position is Ф45, then the MFA can be determined from the
relation M = tan-1 (tan Ф45 / cos 45°), which is precise for rectangular
cells. It was found that 92.93% of the variation of MFA can be
attributed to the distance from pith to bark. Here we shall present our
results of the MFA in the cell wall with respect to its shape, structure
and the distance from pith to park as an important fast check and yet
accurate towards the quality of wood, its uses and application.
Abstract: This paper presents a means for reducing the torque
variation during the revolution of a vertical-axis water turbine
(VAWaterT) by increasing the blade number. For this purpose, twodimensional
CFD analyses have been performed on a straight-bladed
Darrieus-type rotor. After describing the computational model and
the relative validation procedure, a complete campaign of
simulations, based on full RANS unsteady calculations, is proposed
for a three, four and five-bladed rotor architectures, characterized by
a NACA 0025 airfoil. For each proposed rotor configuration, flow
field characteristics are investigated at several values of tip speed
ratio, allowing a quantification of the influence of blade number on
flow geometric features and dynamic quantities, such as rotor torque
and power. Finally, torque and power curves are compared for the
three analyzed architectures, achieving a quantification of the effect
of blade number on overall rotor performance.
Abstract: This paper presents a technical speaker adaptation
method called WMLLR, which is based on maximum likelihood linear
regression (MLLR). In MLLR, a linear regression-based transform
which adapted the HMM mean vectors was calculated to maximize the
likelihood of adaptation data. In this paper, the prior knowledge of the
initial model is adequately incorporated into the adaptation. A series of
speaker adaptation experiments are carried out at a 30 famous city
names database to investigate the efficiency of the proposed method.
Experimental results show that the WMLLR method outperforms the
conventional MLLR method, especially when only few utterances
from a new speaker are available for adaptation.
Abstract: Characteristics and sonocatalytic activity of zeolite
Y catalysts loaded with TiO2 using impregnation and ion exchange
methods for the degradation of amaranth dye were investigated.
The Ion-exchange method was used to encapsulate the TiO2 into
the internal pores of the zeolite while the incorporation of TiO2
mostly on the external surface of zeolite was carried out using the
impregnation method. Different characterization techniques were
used to elucidate the physicochemical properties of the produced
catalysts. The framework of zeolite Y remained virtually
unchanged after the encapsulation of TiO2 while the crystallinity of
zeolite decreased significantly after the incorporation of 15 wt% of
TiO2. The sonocatalytic activity was enhanced by TiO2
incorporation with maximum degradation efficiencies of 50% and
68% for the encapsulated titanium and titanium loaded onto the
zeolite, respectively after 120min of reaction. Catalysts
characteristics and sonocatalytic behaviors were significantly
affected by the preparation method and the location of TiO2
introduced with zeolite structure. Behaviors in the sonocatalytic
process were successfully correlated with the characteristics of the
catalysts used.
Abstract: One problem of synthetic sunflower cultivation is an
erratic germination of the seeds. To improve the germination, presowing
seed treatment with an ultrasound was tested. All treatments
were carried out at 40 kHz frequency with the intensities of 40, 60,
80 and 100% of the ultrasonic generator total power (250 W) for the
durations of 5, 10, 15 and 20 minutes. Data on seed germination
percentage, seed vigor index (SVI), root and shoot lengths of
seedlings were collected. The results showed that germination, SVI,
root and shoot lengths of ultrasonic treated seedlings were different
from the control, depending on intensity of the ultrasound. The
effects of ultrasonic treatment were significant on germination,
resulting in a maximum increase of 43% at 40 and 60% intensities
compared to that of the control seeds. In addition, seedlings of these 2
treatments had higher SVI and longer root and shoot lengths than that
of the control seedlings. All treatment durations resulted in higher
germination and SVI, longer root and higher shoot lenghts of
seedlings than the control. Among the duration treatments, only SVI
and seedling root length were significantly different.
Abstract: The interaction of the blade tip with the casing
boundary layer and the leakage flow may lead to a kind of cavitation
namely tip vortex cavitation. In this study, the onset of tip vortex
cavitation was experimentally investigated in an axial flow pump.
For a constant speed and a fixed angle of attack and by changing the
flow rate, the pump head, input power, output power and efficiency
were calculated and the pump characteristic curves were obtained.
The cavitation phenomenon was observed with a camera and a
stroboscope. Finally, the critical flow region, which tip vortex
cavitation might have occurred, was identified. The results show that
just by adjusting the flow rate, out of the specified region, the
possibility of occurring tip vortex cavitation, decreases to a great
extent.
Abstract: The paper presents the optimization problem for the
multi-element synthetic transmit aperture method (MSTA) in
ultrasound imaging applications. The optimal choice of the transmit
aperture size is performed as a trade-off between the lateral
resolution, penetration depth and the frame rate. Results of the
analysis obtained by a developed optimization algorithm are
presented. Maximum penetration depth and the best lateral resolution
at given depths are chosen as the optimization criteria. The
optimization algorithm was tested using synthetic aperture data of
point reflectors simulated by Filed II program for Matlab® for the
case of 5MHz 128-element linear transducer array with 0.48 mm
pitch are presented. The visualization of experimentally obtained
synthetic aperture data of a tissue mimicking phantom and in vitro
measurements of the beef liver are also shown. The data were
obtained using the SonixTOUCH Research systemequipped with a
linear 4MHz 128 element transducerwith 0.3 mm element pitch, 0.28
mm element width and 70% fractional bandwidth was excited by one
sine cycle pulse burst of transducer's center frequency.
Abstract: As nanotechnology advances, the use of nanotechnology for medical purposes in the field of nanomedicine seems more promising; the rise of nanorobots for medical diagnostics and treatments could be arriving in the near future. This study proposes a swarm intelligence based control mechanism for swarm nanorobots that operate as artificial platelets to search for wounds. The canonical particle swarm optimization algorithm is employed in this study. A simulation in the circulatory system is constructed and used for demonstrating the movement of nanorobots with essential characteristics to examine the performance of proposed control mechanism. The effects of three nanorobot capabilities including their perception range, maximum velocity and respond time are investigated. The results show that canonical particle swarm optimization can be used to control the early version nanorobots with simple behaviors and actions.
Abstract: In this paper we present a method for gene ranking
from DNA microarray data. More precisely, we calculate the correlation
networks, which are unweighted and undirected graphs, from
microarray data of cervical cancer whereas each network represents
a tissue of a certain tumor stage and each node in the network
represents a gene. From these networks we extract one tree for
each gene by a local decomposition of the correlation network. The
interpretation of a tree is that it represents the n-nearest neighbor
genes on the n-th level of a tree, measured by the Dijkstra distance,
and, hence, gives the local embedding of a gene within the correlation
network. For the obtained trees we measure the pairwise similarity
between trees rooted by the same gene from normal to cancerous
tissues. This evaluates the modification of the tree topology due to
progression of the tumor. Finally, we rank the obtained similarity
values from all tissue comparisons and select the top ranked genes.
For these genes the local neighborhood in the correlation networks
changes most between normal and cancerous tissues. As a result
we find that the top ranked genes are candidates suspected to be
involved in tumor growth and, hence, indicates that our method
captures essential information from the underlying DNA microarray
data of cervical cancer.
Abstract: Fuel and oxidant gas delivery plate, or fuel cell
plate, is a key component of a Proton Exchange Membrane (PEM)
fuel cell. To manufacture low-cost and high performance fuel cell
plates, advanced computer modeling and finite element structure
analysis are used as virtual prototyping tools for the optimization
of the plates at the early design stage. The present study examines
thermal stress analysis of the fuel cell plates that are produced
using a patented, low-cost fuel cell plate production technique
based on screen-printing. Design optimization is applied to
minimize the maximum stress within the plate, subject to strain
constraint with both geometry and material parameters as design
variables. The study reveals the characteristics of the printed
plates, and provides guidelines for the structure and material design
of the fuel cell plate.
Abstract: This paper proposed a stiffness analysis method for a
3-PRS mechanism for welding thick aluminum plate using FSW
technology. In the molding process, elastic deformation of lead-screws
and links are taken into account. This method is based on the virtual
work principle. Through a survey of the commonly used stiffness
performance indices, the minimum and maximum eigenvalues of the
stiffness matrix are used to evaluate the stiffness of the 3-PRS
mechanism. Furthermore, A FEA model has been constructed to verify
the method. Finally, we redefined the workspace using the stiffness
analysis method.
Abstract: Heat powered solid sorption is a feasible alternative to
electrical vapor compression refrigeration systems. In this paper,
activated carbon (powder type Maxsorb and fiber type ACF-A10)-
CO2 based adsorption cooling cycles are studied using the pressuretemperature-
concentration (P-T-W) diagram. The specific cooling
effect (SCE) and the coefficient of performance (COP) of these two
cooling systems are simulated for the driving heat source
temperatures ranging from 30 ºC to 90 ºC in terms of different
cooling load temperatures with a cooling source temperature of 25
ºC. It is found from the present analysis that Maxsorb-CO2 couple
shows higher cooling capacity and COP. The maximum COPs of
Maxsorb-CO2 and ACF(A10)-CO2 based cooling systems are found
to be 0.15 and 0.083, respectively. The main innovative feature of
this cooling cycle is the ability to utilize low temperature waste heat
or solar energy using CO2 as the refrigerant, which is one of the best
alternative for applications where flammability and toxicity are not
allowed.
Abstract: This paper evaluates performances of an adaptive noise
cancelling (ANC) based target detection algorithm on a set of real test
data supported by the Defense Evaluation Research Agency (DERA
UK) for multi-target wideband active sonar echolocation system. The
hybrid algorithm proposed is a combination of an adaptive ANC
neuro-fuzzy scheme in the first instance and followed by an iterative
optimum target motion estimation (TME) scheme. The neuro-fuzzy
scheme is based on the adaptive noise cancelling concept with the
core processor of ANFIS (adaptive neuro-fuzzy inference system) to
provide an effective fine tuned signal. The resultant output is then
sent as an input to the optimum TME scheme composed of twogauge
trimmed-mean (TM) levelization, discrete wavelet denoising
(WDeN), and optimal continuous wavelet transform (CWT) for
further denosing and targets identification. Its aim is to recover the
contact signals in an effective and efficient manner and then determine
the Doppler motion (radial range, velocity and acceleration) at very
low signal-to-noise ratio (SNR). Quantitative results have shown that
the hybrid algorithm have excellent performance in predicting targets-
Doppler motion within various target strength with the maximum
false detection of 1.5%.
Abstract: In this paper, a particle swarm optimization (PSO)
algorithm is proposed to solve machine loading problem in flexible
manufacturing system (FMS), with bicriterion objectives of
minimizing system unbalance and maximizing system throughput in
the occurrence of technological constraints such as available
machining time and tool slots. A mathematical model is used to
select machines, assign operations and the required tools. The
performance of the PSO is tested by using 10 sample dataset and the
results are compared with the heuristics reported in the literature. The
results support that the proposed PSO is comparable with the
algorithms reported in the literature.
Abstract: Versatile dual-mode class-AB CMOS four-quadrant
analog multiplier circuit is presented. The dual translinear loops and
current mirrors are the basic building blocks in realization scheme.
This technique provides; wide dynamic range, wide-bandwidth response
and low power consumption. The major advantages of this
approach are; its has single ended inputs; since its input is dual translinear
loop operate in class-AB mode which make this multiplier
configuration interesting for low-power applications; current multiplying,
voltage multiplying, or current and voltage multiplying can
be obtainable with balanced input. The simulation results of versatile
analog multiplier demonstrate a linearity error of 1.2 %, a -3dB bandwidth
of about 19MHz, a maximum power consumption of 0.46mW,
and temperature compensated. Operation of versatile analog multiplier
was also confirmed through an experiment using CMOS transistor
array.
Abstract: In this work, we improve a previously developed
segmentation scheme aimed at extracting edge information from
speckled images using a maximum likelihood edge detector. The
scheme was based on finding a threshold for the probability density
function of a new kernel defined as the arithmetic mean-to-geometric
mean ratio field over a circular neighborhood set and, in a general
context, is founded on a likelihood random field model (LRFM). The
segmentation algorithm was applied to discriminated speckle areas
obtained using simple elliptic discriminant functions based on
measures of the signal-to-noise ratio with fractional order moments.
A rigorous stochastic analysis was used to derive an exact expression
for the cumulative density function of the probability density
function of the random field. Based on this, an accurate probability
of error was derived and the performance of the scheme was
analysed. The improved segmentation scheme performed well for
both simulated and real images and showed superior results to those
previously obtained using the original LRFM scheme and standard
edge detection methods. In particular, the false alarm probability was
markedly lower than that of the original LRFM method with
oversegmentation artifacts virtually eliminated. The importance of
this work lies in the development of a stochastic-based segmentation,
allowing an accurate quantification of the probability of false
detection. Non visual quantification and misclassification in medical
ultrasound speckled images is relatively new and is of interest to
clinicians.
Abstract: In this article, a method has been offered to classify
normal and defective tiles using wavelet transform and artificial
neural networks. The proposed algorithm calculates max and min
medians as well as the standard deviation and average of detail
images obtained from wavelet filters, then comes by feature vectors
and attempts to classify the given tile using a Perceptron neural
network with a single hidden layer. In this study along with the
proposal of using median of optimum points as the basic feature and
its comparison with the rest of the statistical features in the wavelet
field, the relational advantages of Haar wavelet is investigated. This
method has been experimented on a number of various tile designs
and in average, it has been valid for over 90% of the cases. Amongst
the other advantages, high speed and low calculating load are
prominent.
Abstract: In this paper, a plane-strain orthotropic elasto-plastic
dynamic constitutive model is established, and with this constitutive
model, the thermal shock wave induced by intense pulsed X-ray
radiation in cylinder shell composite is simulated by the finite element
code, then the properties of thermal shock wave propagation are
discussed. The results show that the thermal shock wave exhibit
different shapes under the radiation of soft and hard X-ray, and while
the composite is radiated along different principal axes, great
differences exist in some aspects, such as attenuation of the peak stress
value, spallation and so on.
Abstract: Parsing is important in Linguistics and Natural
Language Processing to understand the syntax and semantics of a
natural language grammar. Parsing natural language text is
challenging because of the problems like ambiguity and inefficiency.
Also the interpretation of natural language text depends on context
based techniques. A probabilistic component is essential to resolve
ambiguity in both syntax and semantics thereby increasing accuracy
and efficiency of the parser. Tamil language has some inherent
features which are more challenging. In order to obtain the solutions,
lexicalized and statistical approach is to be applied in the parsing
with the aid of a language model. Statistical models mainly focus on
semantics of the language which are suitable for large vocabulary
tasks where as structural methods focus on syntax which models
small vocabulary tasks. A statistical language model based on Trigram
for Tamil language with medium vocabulary of 5000 words has
been built. Though statistical parsing gives better performance
through tri-gram probabilities and large vocabulary size, it has some
disadvantages like focus on semantics rather than syntax, lack of
support in free ordering of words and long term relationship. To
overcome the disadvantages a structural component is to be
incorporated in statistical language models which leads to the
implementation of hybrid language models. This paper has attempted
to build phrase structured hybrid language model which resolves
above mentioned disadvantages. In the development of hybrid
language model, new part of speech tag set for Tamil language has
been developed with more than 500 tags which have the wider
coverage. A phrase structured Treebank has been developed with 326
Tamil sentences which covers more than 5000 words. A hybrid
language model has been trained with the phrase structured Treebank
using immediate head parsing technique. Lexicalized and statistical
parser which employs this hybrid language model and immediate
head parsing technique gives better results than pure grammar and
trigram based model.