Abstract: Modeling and simulation of biochemical reactions is of great interest in the context of system biology. The central dogma of this re-emerging area states that it is system dynamics and organizing principles of complex biological phenomena that give rise to functioning and function of cells. Cell functions, such as growth, division, differentiation and apoptosis are temporal processes, that can be understood if they are treated as dynamic systems. System biology focuses on an understanding of functional activity from a system-wide perspective and, consequently, it is defined by two hey questions: (i) how do the components within a cell interact, so as to bring about its structure and functioning? (ii) How do cells interact, so as to develop and maintain higher levels of organization and functions? In recent years, wet-lab biologists embraced mathematical modeling and simulation as two essential means toward answering the above questions. The credo of dynamics system theory is that the behavior of a biological system is given by the temporal evolution of its state. Our understanding of the time behavior of a biological system can be measured by the extent to which a simulation mimics the real behavior of that system. Deviations of a simulation indicate either limitations or errors in our knowledge. The aim of this paper is to summarize and review the main conceptual frameworks in which models of biochemical networks can be developed. In particular, we review the stochastic molecular modelling approaches, by reporting the principal conceptualizations suggested by A. A. Markov, P. Langevin, A. Fokker, M. Planck, D. T. Gillespie, N. G. van Kampfen, and recently by D. Wilkinson, O. Wolkenhauer, P. S. Jöberg and by the author.
Abstract: Numerical study of two dimensional supersonic
hydrogen-air mixing layer is performed to investigate the effect of
turbulence and chemical additive on ignition distance. Chemical
reaction is treated using detail kinetics. Advection upstream splitting
method is used to calculate the fluxes and one equation turbulence
model is chosen here to simulate the considered problem. Hydrogen
peroxide is used as an additive and the results show that inflow
turbulence and chemical additive may drastically decrease the
ignition delay in supersonic combustion.
Abstract: We introduce, a new interactive 3D simulation system of ocular motion and expressions suitable for: (1) character animation applications to game design, film production, HCI (Human Computer Interface), conversational animated agents, and virtual reality; (2) medical applications (ophthalmic neurological and muscular pathologies: research and education); and (3) real time simulation of unconscious cognitive and emotional responses (for use, e.g., in psychological research). The system is comprised of: (1) a physiologically accurate parameterized 3D model of the eyes, eyelids, and eyebrow regions; and (2) a prototype device for realtime control of eye motions and expressions, including unconsciously produced expressions, for application as in (1), (2), and (3) above. The 3D eye simulation system, created using state-of-the-art computer animation technology and 'optimized' for use with an interactive and web deliverable platform, is, to our knowledge, the most advanced/realistic available so far for applications to character animation and medical pedagogy.
Abstract: In this report, an OTA which is used in fully
differential pipelined ADC was described. Using gain-boost
architecture with difference-ended amplifier, this OTA achieve
high-gain and high-speed. Besides, the CMFB circuit is also used, and
some methods are concerned to improve the performance. Then, by
optimization the layout design, OTA-s mismatch was reduced. This
design was using TSMC 0.18um CMOS process and simulation both
schematic and layout in Cadence. The result of the simulation shows
that the OTA has a gain up to 80dB,a unity gain bandwidth of about
1.437GHz for a 2pF load, a slew rate is about 428V/μs, a output swing
is 0.2V~1.35V, with the power supply of 1.8V, the power
consumption is 88mW. This amplifier was used in a 10bit 150MHz
pipelined ADC.
Abstract: In this paper, Speed Sensorless Indirect Field Oriented Control (IFOC) of a Permanent Magnet Synchronous machine (PMSM) is studied. The closed loop scheme of the drive system utilizes fuzzy speed and current controllers. Due to the well known drawbacks of the speed sensor, an algorithm is proposed in this paper to eliminate it. In fact, based on the model of the PMSM, the stator currents and rotor speed are estimated simultaneously using adaptive Luenberger observer for currents and MRAS (Model Reference Adaptive System) observer for rotor speed. To overcome the sensivity of this algorithm against parameter variation, adaptive for on line stator resistance tuning is proposed. The validity of the proposed method is verified by an extensive simulation work.
Abstract: Abrasive waterjet is a novel machining process capable of processing wide range of hard-to-machine materials. This research addresses modeling and optimization of the process parameters for this machining technique. To model the process a set of experimental data has been used to evaluate the effects of various parameter settings in cutting 6063-T6 aluminum alloy. The process variables considered here include nozzle diameter, jet traverse rate, jet pressure and abrasive flow rate. Depth of cut, as one of the most important output characteristics, has been evaluated based on different parameter settings. The Taguchi method and regression modeling are used in order to establish the relationships between input and output parameters. The adequacy of the model is evaluated using analysis of variance (ANOVA) technique. The pairwise effects of process parameters settings on process response outputs are also shown graphically. The proposed model is then embedded into a Simulated Annealing algorithm to optimize the process parameters. The optimization is carried out for any desired values of depth of cut. The objective is to determine proper levels of process parameters in order to obtain a certain level of depth of cut. Computational results demonstrate that the proposed solution procedure is quite effective in solving such multi-variable problems.
Abstract: In this article, the design of a Supply Chain Network
(SCN) consisting of several suppliers, production plants, distribution
centers and retailers, is considered. Demands of retailers are
considered stochastic parameters, so we generate amounts of data via
simulation to extract a few demand scenarios. Then a mixed integer
two-stage programming model is developed to optimize
simultaneously two objectives: (1) minimization the fixed and
variable cost, (2) maximization the service level. A weighting method
is utilized to solve this two objective problem and a numerical
example is made to show the performance of the model.
Abstract: Image retrieval is a topic where scientific interest is currently high. The important steps associated with image retrieval system are the extraction of discriminative features and a feasible similarity metric for retrieving the database images that are similar in content with the search image. Gabor filtering is a widely adopted technique for feature extraction from the texture images. The recently proposed sparsity promoting l1-norm minimization technique finds the sparsest solution of an under-determined system of linear equations. In the present paper, the l1-norm minimization technique as a similarity metric is used in image retrieval. It is demonstrated through simulation results that the l1-norm minimization technique provides a promising alternative to existing similarity metrics. In particular, the cases where the l1-norm minimization technique works better than the Euclidean distance metric are singled out.
Abstract: This paper shows how we can integrate
communication modeling into the design modeling at early stages of
the design flow. We consider effect of incorporating noise such as
impulsive noise on system stability. We show that with change of the
system model and investigate the system performance under the
different communication effects. We modeled a unmanned aerial
vehicle (UAV) as a demonstration using SystemC methodology.
Moreover the system is modeled by joining the capabilities of UML
and SystemC to operate at system level.
Abstract: In recent years, Radio Frequency Identification (RFID)
is followed with interest by many researches, especially for the
purpose of indoor positioning as the innate properties of RFID are
profitable for achieving it. A lot of algorithms or schemes are proposed
to be used in the RFID-based positioning system, but most of them are
lack of environmental consideration and it induces inaccuracy of
application. In this research, a lot of algorithms and schemes of RFID
indoor positioning are discussed to see whether effective or not on
application, and some rules are summarized for achieving accurate
positioning. On the other hand, a new term “Noise Factor" is involved
to describe the signal loss between the target and the obstacle. As a
result, experimental data can be obtained but not only simulation; and
the performance of the positioning system can be expressed
substantially.
Abstract: The LMS adaptive filter has several parameters which can affect their performance. From among these parameters, most papers handle the step size parameter for controlling the performance. In this paper, we approach three parameters: step-size, filter tap-size and filter form. The regression analysis is used for defining the relation between parameters and performance of LMS adaptive filter with using the system level simulation results. The results present that all parameters have performance trends in each own particular form, which can be estimated from equations drawn by regression analysis.
Abstract: In Orthogonal Frequency Division Multiplexing (OFDM) systems, the peak to average power ratio (PAR) is much high. The clipping signal scheme is a useful method to reduce PAR. Clipping the OFDM signal, however, increases the overall noise level by introducing clipping noise. It is necessary to recover the figure of the original signal at receiver in order to reduce the clipping noise. Considering the continuity of the signal and the figure of the peak, we obtain a certain conic function curve to replace the clipped signal module within the clipping time. The results of simulation show that the proposed scheme can reduce the systems? BER (bit-error rate) 10 times when signal-to-interference-and noise-ratio (SINR) equals to 12dB. And the BER performance of the proposed scheme is superior to that of kim's scheme, too.
Abstract: Dynamic shear test on simulated phantom can be used
to validate magnetic resonance elastography (MRE) measurements.
Phantom gel has been usually utilized for the cell culture of cartilage
and soft tissue and also been used for mechanical property
characterization using imaging systems. The viscoelastic property of
the phantom would be important for dynamic experiments and
analyses. In this study, An axisymmetric FE model is presented for
determining the dynamic shear behaviour of brain simulated phantom
using ABAQUS. The main objective of this study was to investigate
the effect of excitation frequencies and boundary conditions on shear
modulus and shear viscosity in viscoelastic media.
Abstract: In the present paper the results of a numerical study are presented, numerical models were developed to simulate the behaviour of vertical massive dikes. The proposed models were developed according to the geometry, boundary conditions, loading conditions and initial conditions of a physical model taken as reference. The results obtained were compared to the experimental data. As far as the overall behaviour, the displacements and the failure mechanisms of the dikes is concerned, the numerical results were in good agreement with the experimental results, which clearly indicates a good quality of numerical modelling. The validated numerical models were used in a parametric study were the displacements and failure mechanisms were fully investigated. Out of the results obtained, some conclusions and recommendations related to the design of massive dikes are proposed.
Abstract: Mobile robots are used in a large field of scenarios,
like exploring contaminated areas, repairing oil rigs under water,
finding survivors in collapsed buildings, etc. Currently, there is no
unified intuitive user interface (UI) to control such complex mobile
robots. As a consequence, some scenarios are done without the
exploitation of experience and intuition of human teleoperators.
A novel framework has been developed to embed a flexible and
modular UI into a complete 3-D virtual reality simulation system.
This new approach wants to access maximum benefits of human
operators. Sensor information received from the robot is prepared for
an intuitive visualization. Virtual reality metaphors support the
operator in his decisions. These metaphors are integrated into a real
time stereo video stream. This approach is not restricted to any
specific type of mobile robot and allows for the operation of different
robot types with a consistent concept and user interface.
Abstract: The fundamental aim of extended expansion concept is
to achieve higher work done which in turn leads to higher thermal
efficiency. This concept is compatible with the application of
turbocharger and LHR engine. The Low Heat Rejection engine was
developed by coating the piston crown, cylinder head inside with
valves and cylinder liner with partially stabilized zirconia coating of
0.5 mm thickness. Extended expansion in diesel engines is termed as
Miller cycle in which the expansion ratio is increased by reducing the
compression ratio by modifying the inlet cam for late inlet valve
closing. The specific fuel consumption reduces to an appreciable level
and the thermal efficiency of the extended expansion turbocharged
LHR engine is improved.
In this work, a thermodynamic model was formulated and
developed to simulate the LHR based extended expansion
turbocharged direct injection diesel engine. It includes a gas flow
model, a heat transfer model, and a two zone combustion model. Gas
exchange model is modified by incorporating the Miller cycle, by
delaying inlet valve closing timing which had resulted in considerable
improvement in thermal efficiency of turbocharged LHR engines. The
heat transfer model, calculates the convective and radiative heat
transfer between the gas and wall by taking into account of the
combustion chamber surface temperature swings. Using the two-zone
combustion model, the combustion parameters and the chemical
equilibrium compositions were determined. The chemical equilibrium
compositions were used to calculate the Nitric oxide formation rate by
assuming a modified Zeldovich mechanism. The accuracy of this
model is scrutinized against actual test results from the engine. The
factors which affect thermal efficiency and exhaust emissions were
deduced and their influences were discussed. In the final analysis it is
seen that there is an excellent agreement in all of these evaluations.
Abstract: Electromagnetic flow meter by measuring the varying of magnetic flux, which is related to the velocity of conductive flow, can measure the rate of fluids very carefully and precisely. Electromagnetic flow meter operation is based on famous Faraday's second Law. In these equipments, the constant magnetostatic field is produced by electromagnet (winding around the tube) outside of pipe and inducting voltage that is due to conductive liquid flow is measured by electrodes located on two end side of the pipe wall. In this research, we consider to 2-dimensional mathematical model that can be solved by numerical finite difference (FD) solution approach to calculate induction potential between electrodes. The fundamental concept to design the electromagnetic flow meter, exciting winding and simulations are come out by using MATLAB and PDE-Tool software. In the last stage, simulations results will be shown for improvement and accuracy of technical provision.
Abstract: In this paper, an intelligent automatic parking control method is proposed. First, the dynamical equation of the rear parking control is derived. Then a fuzzy logic control is proposed to perform the parking planning process. Further, a rear neural network is proposed for the steering control. Through the simulations and experiments, the intelligent auto-parking mode controllers have been shown to achieve the demanded goals with satisfactory control performance and to guarantee the system robustness under parametric variations and external disturbances. To improve some shortcomings and limitations in conventional parking mode control and further to reduce consumption time and prime cost.
Abstract: In this paper we consider a nonlinear feedback control
called augmented automatic choosing control (AACC) for nonlinear
systems with constrained input using weighted gradient optimization
automatic choosing functions. Constant term which arises from
linearization of a given nonlinear system is treated as a coefficient of
a stable zero dynamics. Parameters of the control are suboptimally
selected by maximizing the stable region in the sense of Lyapunov
with the aid of a genetic algorithm. This approach is applied to a
field excitation control problem of power system to demonstrate the
splendidness of the AACC. Simulation results show that the new
controller can improve performance remarkably well.
Abstract: Several methods are available for weight and shape
optimization of structures, among which Evolutionary Structural
Optimization (ESO) is one of the most widely used methods. In ESO,
however, the optimization criterion is completely case-dependent.
Moreover, only the improving solutions are accepted during the
search. In this paper a Simulated Annealing (SA) algorithm is used
for structural optimization problem. This algorithm differs from other
random search methods by accepting non-improving solutions. The
implementation of SA algorithm is done through reducing the
number of finite element analyses (function evaluations).
Computational results show that SA can efficiently and effectively
solve such optimization problems within short search time.