Abstract: We present an integration approach of a CMOS biosensor into a polymer based microfluidic environment suitable for mass production. It consists of a wafer-level-package for the silicon die and laser bonding process promoted by an intermediate hot melt foil to attach the sensor package to the microfluidic chip, without the need for dispensing of glues or underfiller. A very good condition of the sensing area was obtained after introducing a protection layer during packaging. A microfluidic flow cell was fabricated and shown to withstand pressures up to Δp = 780 kPa without leakage. The employed biosensors were electrically characterized in a dry environment.
Abstract: Chikungunya virus (CHICKV) is an arboviruses belonging to family Tagoviridae and is transmitted to human through by mosquito (Aedes aegypti and Aedes albopictus) bite. A large outbreak of chikungunya has been reported in India between 2006 and 2007, along with several other countries from South-East Asia and for the first time in Europe. It was for the first time that the CHICKV outbreak has been reported with mortality from Reunion Island and increased mortality from Asian countries. CHICKV affects all age groups, and currently there are no specific drugs or vaccine to cure the disease. The need of antiviral agents for the treatment of CHICKV infection and the success of virtual screening against many therapeutically valuable targets led us to carry out the structure based drug design against Chikungunya nSP2 protease (PDB: 3TRK). Highthroughput virtual screening of publicly available databases, ZINC12 and BindingDB, has been carried out using the Openeye tools and Schrodinger LLC software packages. Openeye Filter program has been used to filter the database and the filtered outputs were docked using HTVS protocol implemented in GLIDE package of Schrodinger LLC. The top HITS were further used for enriching the similar molecules from the database through vROCS; a shape based screening protocol implemented in Openeye. The approach adopted has provided different scaffolds as HITS against CHICKV protease. Three scaffolds: Indole, Pyrazole and Sulphone derivatives were selected based on the docking score and synthetic feasibility. Derivatives of Pyrazole were synthesized and submitted for antiviral screening against CHICKV.
Abstract: this study was carried out to investigate the changes in
quality parameters of rye bread packaged in different polymer films
during convection air-flow thermal treatment process. Whole loafs of
bread were placed in polymer pouches, which were sealed in reduced
pressure air ambiance, bread was thermally treated in
at temperature +(130; 140; and 150) ± 5 ºC within 40min, as long as
the core temperature of the samples have reached accordingly
+80±1 ºC. For bread packaging pouches were used: anti-fog
Mylar®OL12AF and thermo resistant combined polymer material.
Main quality parameters was analysed using standard methods:
temperature in bread core, bread crumb and crust firmness value,
starch granules volume and microflora. In the current research it was
proved, that polymer films significantly influence rye bread quality
parameters changes during thermal treatment. Thermo resistant
combined polymer material film could be recommendable for
packaged rye bread pasteurization, for maximal bread quality
parameter keeping.
Abstract: This paper describes topic of computer simulation with regard to the ground movement above an underground mine. Simulation made with software package ADINA for nonlinear elastic-plastic analysis with finite elements method. The one of representative profiles from Mine 'Stara Jama' in Zenica has been investigated. A collection and selection of both geo-mechanical data and geometric parameters of the mine was necessary for performing these simulations. Results of estimation have been compared with measured values (vertical displacement of surface), and then simulation performed with assumed dynamic and dimensions of excavation, over a period of time. Results are presented with bitmaps and charts.
Abstract: Having done in this study, air-conditioning
automation for patisserie shopwindow was designed. In the cooling
sector it is quite important to cooling up the air temperature in the
shopwindow within short time interval. Otherwise the patisseries
inside of the shopwindow will be spoilt in a few days. Additionally
the humidity is other important parameter for the patisseries kept in
shopwindow. It must be raised up to desired level in a quite short
time. Traditional patisserie shopwindows only allow controlling
temperature manually. There is no humidity control and humidity is
supplied by fans that are directed to the water at the bottom of the
shopwindows. In this study, humidity and temperature sensors
(SHT11), PIC, AC motor controller, DC motor controller, ultrasonic
nebulizer and other electronic circuit members were used to simulate
air conditioning automation for patisserie shopwindow in proteus
software package. The simulation results showed that temperature
and humidity values are adjusted in desired time duration by openloop
control technique. Outer and inner temperature and humidity
values were used for control mechanism.
Abstract: This paper focuses on a critical component of the situational awareness (SA), the control of autonomous vertical flight for tactical unmanned aerial vehicle (TUAV). With the SA strategy, we proposed a two stage flight control procedure using two autonomous control subsystems to address the dynamics variation and performance requirement difference in initial and final stages of flight trajectory for an unmanned helicopter model with coaxial rotor and ducted fan configuration. This control strategy for chosen model of TUAV has been verified by simulation of hovering maneuvers using software package Simulink and demonstrated good performance for fast stabilization of engines in hovering, consequently, fast SA with economy in energy can be asserted during search-and-rescue operations.
Abstract: Trends in business intelligence, e-commerce and
remote access make it necessary and practical to store data in
different ways on multiple systems with different operating systems.
As business evolve and grow, they require efficient computerized
solution to perform data update and to access data from diverse
enterprise business applications. The objective of this paper is to
demonstrate the capability of DTS [1] as a database solution for
automatic data transfer and update in solving business problem. This
DTS package is developed for the sales of variety of plants and
eventually expanded into commercial supply and landscaping
business. Dimension data modeling is used in DTS package to
extract, transform and load data from heterogeneous database
systems such as MySQL, Microsoft Access and Oracle that
consolidates into a Data Mart residing in SQL Server. Hence, the
data transfer from various databases is scheduled to run automatically
every quarter of the year to review the efficient sales analysis.
Therefore, DTS is absolutely an attractive solution for automatic data
transfer and update which meeting today-s business needs.
Abstract: We present a dual-band (Cellular & PCS) dual-path
zero-IF receiver for CDMA2000 diversity, monitoring and
simultaneous-GPS. The secondary path is a SAW-less diversity
CDMA receiver which can be also used for advanced features like
monitoring when supported with an additional external VCO. A GPS
receiver is integrated with its dedicated VCO allowing simultaneous
positioning during a cellular call. The circuit is implemented in a
0.25μm 40GHz-fT BiCMOS process and uses a HVQFN 56-pin
package. It consumes a maximum 300mW from a 2.8V supply in
dual-modes. The chip area is 12.8mm2.
Abstract: Nowadays companies strive to survive in a
competitive global environment. To speed up product
development/modifications, it is suggested to adopt a collaborative
product development approach. However, despite the advantages of
new IT improvements still many CAx systems work separately and
locally. Collaborative design and manufacture requires a product
information model that supports related CAx product data models. To
solve this problem many solutions are proposed, which the most
successful one is adopting the STEP standard as a product data model
to develop a collaborative CAx platform. However, the improvement
of the STEP-s Application Protocols (APs) over the time, huge
number of STEP AP-s and cc-s, the high costs of implementation,
costly process for conversion of older CAx software files to the STEP
neutral file format; and lack of STEP knowledge, that usually slows
down the implementation of the STEP standard in collaborative data
exchange, management and integration should be considered. In this
paper the requirements for a successful collaborative CAx system is
discussed. The STEP standard capability for product data integration
and its shortcomings as well as the dominant platforms for supporting
CAx collaboration management and product data integration are
reviewed. Finally a platform named LAYMOD to fulfil the
requirements of CAx collaborative environment and integrating the
product data is proposed. The platform is a layered platform to enable
global collaboration among different CAx software
packages/developers. It also adopts the STEP modular architecture
and the XML data structures to enable collaboration between CAx
software packages as well as overcoming the STEP standard
limitations. The architecture and procedures of LAYMOD platform
to manage collaboration and avoid contradicts in product data
integration are introduced.
Abstract: One of the most important aspects expected from an
ERP system is to mange user\administrator manual documents
dynamically. Since an ERP package is frequently changed during its
implementation in customer sites, it is often needed to add new
documents and/or apply required changes to existing documents in
order to cover new or changed capabilities. The worse is that since
these changes occur continuously, the corresponding documents
should be updated dynamically; otherwise, implementing the ERP
package in the organization encounters serious risks. In this paper, we
propose a new architecture which is based on the agent oriented
vision and supplies the dynamic document generation expected from
ERP systems using several independent but cooperative agents.
Beside the dynamic document generation which is the main issue of
this paper, the presented architecture will address some aspects of
intelligence and learning capabilities existing in ERP.
Abstract: The purpose of this research was to study the factors
that influenced the success of mobile phone entrepreneurs at Central
Plaza. The sample group included 187 entrepreneurs at Central Plaza.
A questionnaire was utilized as a tool to collect data. Statistics used
in this research included frequency, percentage, mean, and standard
deviation. Independent- sample t- test, one way ANOVA, and
multiple regression analysis. Data were analyzed by using Statistical
Package for the Social Sciences.The findings disclosed that the
majority of respondents were male between 25-40 years old, and held
an undergraduate degree. The average income of respondents was
between 15,001-25,000 baht. The majority of respondents had less
than 5 years of working experience.
In terms of personality, the findings revealed that expression and
agreement were ranked at the highest level. Whereas, emotion
stability, consciousness, open to new experience were ranked at high.
From the hypotheses testing, the findings revealed that different
genders had different success in their mobile phone business with
different income from the last 6 months. However, difference in age,
income, level of education, and experience affected the success in
terms of income, number of customers, and overall success of
business. Moreover, the factors of personalities included expression,
agreement, emotion stability, consciousness, open to new experience,
and competitive strategy. From the findings, these factors were able
to predict mobile phone business success at 66.9 percent.
Abstract: Application of Expert System in the area of agriculture would take the form of Integrated Crop Management decision aids and would encompass water management, fertilizer management, crop protection systems and identification of implements. In order to remain competitive, the modern farmer often relies on agricultural specialists and advisors to provide information for decision-making. An expert system normally composed of a knowledge base (information, heuristics, etc.), inference engine (analyzes knowledge base), and end user interface (accepting inputs, generating outputs). Software named 'CROP-9-DSS' incorporating all modern features like, graphics, photos, video clippings etc. has been developed. This package will aid as a decision support system for identification of pest and diseases with control measures, fertilizer recommendation system, water management system and identification of farm implements for leading crops of Kerala (India) namely Coconut, Rice, Cashew, Pepper, Banana, four vegetables like Amaranthus, Bhindi, Brinjal and Cucurbits. 'CROP-9-DSS' will act as an expert system to agricultural officers, scientists in the field of agriculture and extension workers for decision-making and help them in suggesting suitable recommendations.
Abstract: In the current work, a numerical parametric study was
performed in order to model the fluid mechanics in the riser of a
bubbling fluidized bed (BFB). The gas-solid flow was simulated by
mean of a multi-fluid Eulerian model incorporating the kinetic theory
for solid particles. The bubbling fluidized bed was simulated two
dimensionally by mean of a Computational Fluid Dynamic (CFD)
commercial software package, Fluent. The effects of using different
inter-phase drag function (the drag model of Gidaspow, Syamlal and
O-Brien and the EMMS drag model) on the model predictions were
evaluated and compared. The results showed that the drag models of
Gidaspow and Syamlal and O-Brien overestimated the drag force for
the FCC particles and predicted a greater bed expansion in
comparison to the EMMS drag model.
Abstract: The study examined the influence of pay differentials on employee retention in the State Colleges of Education in the South-South Region of Nigeria. 275 subjects drawn from members of the wage negotiating teams in the Colleges were administered questionnaires constructed for study. Analysis of Variance revealed that the observed pay differentials significantly influenced retainership, f(5,269 = 6.223, P< 0.05). However, the Multiple Classification Analysis and Post-Hoc test indicated that employees in two of the Colleges with slightly lower and higher pay levels may probably remain with their employers while employees in other Colleges with the least and highest pay levels suggested quitting. Based on these observations, the influence of pay on employee retention seems inconclusive. Generally, employees in the colleges studied are dissatisfied with current pay levels. Management should confront these challenges by improving pay packages to encourage employees to remain and be dedicated to duty.
Abstract: This study experimentally investigates the heat transfer effects of forced convection and natural convection under different substrate openings design. A computational fluid dynamics (CFD) model was established and implemented to verify and explain the experimental results and heat transfer behavior. It is found that different opening position will destroy the growth of the boundary layer on substrates to alter the cooling ability for both forced under low Reynolds number and natural convection. Nevertheless, having too many opening may reduce heat conduction and affect the overall heat transfer performance. This study provides future researchers with a guideline on designing and electronic package manufacturing.
Abstract: This paper focuses on a critical component of the situational awareness (SA), the neural control of autonomous constant depth flight of an autonomous underwater vehicle (AUV). Autonomous constant depth flight is a challenging but important task for AUVs to achieve high level of autonomy under adverse conditions. The fundamental requirement for constant depth flight is the knowledge of the depth, and a properly designed controller to govern the process. The AUV, named VORAM, is used as a model for the verification of the proposed hybrid control algorithm. Three neural network controllers, named NARMA-L2 controllers, are designed for fast and stable diving maneuvers of chosen AUV model. This hybrid control strategy for chosen AUV model has been verified by simulation of diving maneuvers using software package Simulink and demonstrated good performance for fast SA in real-time searchand- rescue operations.
Abstract: One of the robust fault detection filter (RFDF)
designing method is based on sliding-mode theory. The main purpose
of our study is to introduce an innovative simplified reference
residual model generator to formulate the RFDF as a sliding-mode
observer without any manipulation package or transformation matrix,
through which the generated residual signals can be evaluated. So the
proposed design is more explicit and requires less design parameters
in comparison with approaches requiring changing coordinates. To
the best author's knowledge, this is the first time that the sliding
mode technique is applied to detect actuator and sensor faults in a
real boiler. The designing procedure is proposed in a drum boiler in
Synvendska Kraft AB Plant in Malmo, Sweden as a multivariable
and strongly coupled system. It is demonstrated that both sensor and
actuator faults can robustly be detected. Also sensor faults can be
diagnosed and isolated through this method.
Abstract: This paper deals with the application of artificial
neural network (ANN) and fuzzy based Adaptive Neuro Fuzzy
Inference System(ANFIS) approach to Load Frequency Control
(LFC) of multi unequal area hydro-thermal interconnected power
system. The proposed ANFIS controller combines the advantages of
fuzzy controller as well as quick response and adaptability nature of
ANN. Area-1 and area-2 consists of thermal reheat power plant
whereas area-3 and area-4 consists of hydro power plant with electric
governor. Performance evaluation is carried out by using intelligent
controller like ANFIS, ANN and Fuzzy controllers and conventional
PI and PID control approaches. To enhance the performance of
intelligent and conventional controller sliding surface is included.
The performances of the controllers are simulated using
MATLAB/SIMULINK package. A comparison of ANFIS, ANN,
Fuzzy, PI and PID based approaches shows the superiority of
proposed ANFIS over ANN & fuzzy, PI and PID controller for 1%
step load variation.
Abstract: Since the beginning of human history, human
activities have caused many changes in the environment. Today, a
particular attention should be paid to gaining knowledge about water
quality of wetlands which are pristine natural environments rich in
genetic reserves. If qualitative conditions of industrial areas (in terms
of both physicochemical and biological conditions) are not addressed
properly, they could cause disruption in natural ecosystems,
especially in rivers. With regards to the quality of water resources,
determination of pollutant sources plays a pivotal role in engineering
projects as well as designing water quality control systems. Thus,
using different methods such as flow duration curves, dischargepollution
load model and frequency analysis by HYFA software
package, risk of various industrial pollutants in international and
ecologically important Gavkhoni wetland is analyzed. In this study, a
station located at Varzaneh City is used as the last station on
Zayanderud River, from where the river water is discharged into the
wetland. Results showed that elements- concentrations often
exceeded the allowed level and river water can endanger regional
ecosystem. In addition, if the river discharge is managed on Q25
basis, this basis can lower concentrations of elements, keeping them
within the normal level.
Abstract: This paper presents a controller design technique for
Synchronous Reluctance Motor to improve its dynamic performance
with fast response and high accuracy. The sliding mode control is the
most attractive and suitable method to use for this purpose, since it is
simple in design and for its insensitivity to parameter variations or
external disturbances. When this method implemented it yields fast
dynamic response without overshoot and a zero steady-state error.
The current loop control with decentralized sliding mode is presented
in this paper. The mathematical model for the synchronous machine,
the inverter and the controller is developed. The stability of the
sliding mode controller is analyzed. Simulation of synchronous
reluctance motor and the controller with PWM-inverter has been
curried out, using the SIMULINK software package of MATLAB.
Simulation results are presented to show the effectiveness of the
approach.