Abstract: Cancers could normally be marked by a number of
differentially expressed genes which show enormous potential as
biomarkers for a certain disease. Recent years, cancer classification
based on the investigation of gene expression profiles derived by
high-throughput microarrays has widely been used. The selection of
discriminative genes is, therefore, an essential preprocess step in
carcinogenesis studies. In this paper, we have proposed a novel gene
selector using information-theoretic measures for biological
discovery. This multivariate filter is a four-stage framework through
the analyses of feature relevance, feature interdependence, feature
redundancy-dependence and subset rankings, and having been
examined on the colon cancer data set. Our experimental result show
that the proposed method outperformed other information theorem
based filters in all aspect of classification errors and classification
performance.
Abstract: Characteristics and sonocatalytic activity of zeolite
Y catalysts loaded with TiO2 using impregnation and ion exchange
methods for the degradation of amaranth dye were investigated.
The Ion-exchange method was used to encapsulate the TiO2 into
the internal pores of the zeolite while the incorporation of TiO2
mostly on the external surface of zeolite was carried out using the
impregnation method. Different characterization techniques were
used to elucidate the physicochemical properties of the produced
catalysts. The framework of zeolite Y remained virtually
unchanged after the encapsulation of TiO2 while the crystallinity of
zeolite decreased significantly after the incorporation of 15 wt% of
TiO2. The sonocatalytic activity was enhanced by TiO2
incorporation with maximum degradation efficiencies of 50% and
68% for the encapsulated titanium and titanium loaded onto the
zeolite, respectively after 120min of reaction. Catalysts
characteristics and sonocatalytic behaviors were significantly
affected by the preparation method and the location of TiO2
introduced with zeolite structure. Behaviors in the sonocatalytic
process were successfully correlated with the characteristics of the
catalysts used.
Abstract: In this study, active tendons with Proportional Integral
Derivation type controllers were applied to a SDOF and a MDOF
building model. Physical models of buildings were constituted with
virtual springs, dampers and rigid masses. After that, equations of
motion of all degrees of freedoms were obtained. Matlab Simulink
was utilized to obtain the block diagrams for these equations of
motion. Parameters for controller actions were found by using a trial
method. After earthquake acceleration data were applied to the
systems, building characteristics such as displacements, velocities,
accelerations and transfer functions were analyzed for all degrees of
freedoms. Comparisons on displacement vs. time, velocity vs. time,
acceleration vs. time and transfer function (Db) vs. frequency (Hz)
were made for uncontrolled and controlled buildings. The results
show that the method seems feasible.
Abstract: Current research has explored the impact of
instructional immediacy, defined as those behaviors that help build
close relationships or feelings of closeness, both on cognition and
motivation in the traditional classroom and online classroom;
however, online courses continue to suffer from higher dropout rates.
Based on Albert Bandura-s Social Cognitive Theory, four primary
relationships or interactions in an online course will be explored in
light of how they can provide immediacy thereby reducing student
attrition and improving cognitive learning. The four relationships are
teacher-student, student-student, and student-content, and studentcomputer.
Results of a study conducted with inservice teachers
completing a 14-week online professional development technology
course will be examined to demonstrate immediacy strategies that
improve cognitive learning and reduce student attrition. Results of
the study reveal that students can be motivated through various
interactions and instructional immediacy behaviors which lead to
higher completion rates, improved self-efficacy, and cognitive
learning.
Abstract: The interaction of the blade tip with the casing
boundary layer and the leakage flow may lead to a kind of cavitation
namely tip vortex cavitation. In this study, the onset of tip vortex
cavitation was experimentally investigated in an axial flow pump.
For a constant speed and a fixed angle of attack and by changing the
flow rate, the pump head, input power, output power and efficiency
were calculated and the pump characteristic curves were obtained.
The cavitation phenomenon was observed with a camera and a
stroboscope. Finally, the critical flow region, which tip vortex
cavitation might have occurred, was identified. The results show that
just by adjusting the flow rate, out of the specified region, the
possibility of occurring tip vortex cavitation, decreases to a great
extent.
Abstract: The common bean is the most important grain legume for direct human consumption in the world and BCMV is one of the world's most serious bean diseases that can reduce yield and quality of harvested product. To determine the best tolerance index to BCMV and recognize tolerant genotypes, 2 experiments were conducted in field conditions. Twenty five common bean genotypes were sown in 2 separate RCB design with 3 replications under contamination and non-contamination conditions. On the basis of the results of indices correlations GMP, MP and HARM were determined as the most suitable tolerance indices. The results of principle components analysis indicated 2 first components totally explained 98.52% of variations among data. The first and second components were named potential yield and stress susceptible respectively. Based on the results of BCMV tolerance indices assessment and biplot analysis WA8563-4, WA8563-2 and Cardinal were the genotypes that exhibited potential seed yield under contamination and noncontamination conditions.
Abstract: The paper presents the optimization problem for the
multi-element synthetic transmit aperture method (MSTA) in
ultrasound imaging applications. The optimal choice of the transmit
aperture size is performed as a trade-off between the lateral
resolution, penetration depth and the frame rate. Results of the
analysis obtained by a developed optimization algorithm are
presented. Maximum penetration depth and the best lateral resolution
at given depths are chosen as the optimization criteria. The
optimization algorithm was tested using synthetic aperture data of
point reflectors simulated by Filed II program for Matlab® for the
case of 5MHz 128-element linear transducer array with 0.48 mm
pitch are presented. The visualization of experimentally obtained
synthetic aperture data of a tissue mimicking phantom and in vitro
measurements of the beef liver are also shown. The data were
obtained using the SonixTOUCH Research systemequipped with a
linear 4MHz 128 element transducerwith 0.3 mm element pitch, 0.28
mm element width and 70% fractional bandwidth was excited by one
sine cycle pulse burst of transducer's center frequency.
Abstract: The number of framework conceived for e-learning
constantly increase, unfortunately the creators of learning materials
and educational institutions engaged in e-formation adopt a
“proprietor" approach, where the developed products (courses,
activities, exercises, etc.) can be exploited only in the framework
where they were conceived, their uses in the other learning
environments requires a greedy adaptation in terms of time and
effort. Each one proposes courses whose organization, contents,
modes of interaction and presentations are unique for all learners,
unfortunately the latter are heterogeneous and are not interested by
the same information, but only by services or documents adapted to
their needs. Currently the new tendency for the framework
conceived for e-learning, is the interoperability of learning materials,
several standards exist (DCMI (Dublin Core Metadata Initiative)[2],
LOM (Learning Objects Meta data)[1], SCORM (Shareable Content
Object Reference Model)[6][7][8], ARIADNE (Alliance of Remote
Instructional Authoring and Distribution Networks for Europe)[9],
CANCORE (Canadian Core Learning Resource Metadata
Application Profiles)[3]), they converge all to the idea of learning
objects. They are also interested in the adaptation of the learning
materials according to the learners- profile. This article proposes an
approach for the composition of courses adapted to the various
profiles (knowledge, preferences, objectives) of learners, based on
two ontologies (domain to teach and educational) and the learning
objects.
Abstract: Pakistani doctors (MBBS) are emigrating towards developed countries for professional adjustments. This study aims to highlight causes and consequences of doctors- brain drain from Pakistan. Primary data was collected from Mayo Hospital, Lahore by interviewing doctors (n=100) through systematic random sampling technique. It found that various socio-economic and political conditions are working as push and pull factors for brain drain of doctors in Pakistan. Majority of doctors (83%) declared poor remunerations and professional infrastructure of health department as push factor of doctors- brain drain. 81% claimed that continuous instability in political situation and threats of terrorism are responsible for emigration of doctors. 84% respondents considered fewer opportunities of further studies responsible for their emigration. Brain drain of doctors is affecting health sector-s policies / programs, standard doctor-patient ratios and quality of health services badly.
Abstract: The topic of surface flattening plays a vital role in the field of computer aided design and manufacture. Surface flattening enables the production of 2D patterns and it can be used in design and manufacturing for developing a 3D surface to a 2D platform, especially in fashion design. This study describes surface flattening based on minimum energy methods according to the property of different fabrics. Firstly, through the geometric feature of a 3D surface, the less transformed area can be flattened on a 2D platform by geodesic. Then, strain energy that has accumulated in mesh can be stably released by an approximate implicit method and revised error function. In some cases, cutting mesh to further release the energy is a common way to fix the situation and enhance the accuracy of the surface flattening, and this makes the obtained 2D pattern naturally generate significant cracks. When this methodology is applied to a 3D mannequin constructed with feature lines, it enhances the level of computer-aided fashion design. Besides, when different fabrics are applied to fashion design, it is necessary to revise the shape of a 2D pattern according to the properties of the fabric. With this model, the outline of 2D patterns can be revised by distributing the strain energy with different results according to different fabric properties. Finally, this research uses some common design cases to illustrate and verify the feasibility of this methodology.
Abstract: A new chelating resin is prepared by coupling Amberlite XAD-4 with 1-amino-2-naphthole through an azo spacer. The resulting sorbent has been characterized by FT-IR, elemental analysis and thermogravimetric analysis (TGA) and studied for preconcentrating of Fe (II) using flame atomic absorption spectrometry (FAAS) for metal monitoring. The optimum pH value for sorption of the iron ions was 6.5. The resin was subjected to evaluation through batch binding of mentioned metal ion. Quantitative desorption occurs instantaneously with 0.5 M HNO3. The sorption capacity was found 4.1 mmol.g-1 of resin for Fe (II) in the aqueous solution. The chelating resin can be reused for 10 cycles of sorption-desorption without any significant change in sorption capacity. A recovery of 97% was obtained the metal ions with 0.5 M HNO3 as eluting agent. The method was applied for metal ions determination from industrial waste water sample.
Abstract: As nanotechnology advances, the use of nanotechnology for medical purposes in the field of nanomedicine seems more promising; the rise of nanorobots for medical diagnostics and treatments could be arriving in the near future. This study proposes a swarm intelligence based control mechanism for swarm nanorobots that operate as artificial platelets to search for wounds. The canonical particle swarm optimization algorithm is employed in this study. A simulation in the circulatory system is constructed and used for demonstrating the movement of nanorobots with essential characteristics to examine the performance of proposed control mechanism. The effects of three nanorobot capabilities including their perception range, maximum velocity and respond time are investigated. The results show that canonical particle swarm optimization can be used to control the early version nanorobots with simple behaviors and actions.
Abstract: Text-based game is supposed to be a low resource
consumption application that delivers good performances when
compared to graphical-intensive type of games. But, nowadays, some
of the online text-based games are not offering performances that are
acceptable to the users. Therefore, an online text-based game called
Star_Quest has been developed in order to analyze its behavior under
different performance measurements. Performance metrics such as
throughput, scalability, response time and page loading time are
captured to yield the performance of the game. The techniques in
performing the load testing are also disclosed to exhibit the viability
of our work. The comparative assessment between the results
obtained and the accepted level of performances are conducted as to
determine the performance level of the game. The study reveals that
the developed game managed to meet all the performance objectives
set forth.
Abstract: Gold passbook is an investing tool that is especially
suitable for investors to do small investment in the solid gold. The gold
passbook has the lower risk than other ways investing in gold, but its
price is still affected by gold price. However, there are many factors
can cause influences on gold price. Therefore, building a model to
predict the price of gold passbook can both reduce the risk of
investment and increase the benefits. This study investigates the
important factors that influence the gold passbook price, and utilize
the Group Method of Data Handling (GMDH) to build the predictive
model. This method can not only obtain the significant variables but
also perform well in prediction. Finally, the significant variables of
gold passbook price, which can be predicted by GMDH, are US dollar
exchange rate, international petroleum price, unemployment rate,
whole sale price index, rediscount rate, foreign exchange reserves,
misery index, prosperity coincident index and industrial index.
Abstract: This paper suggests an improved integer frequency
offset (IFO) estimation scheme using P1 symbol for orthogonal
frequency division multiplexing (OFDM) based the second generation
terrestrial digital video broadcasting (DVB-T2) system. Proposed
IFO estimator is designed by a low-complexity blind IFO estimation
scheme, which is implemented with complex additions. Also, we
propose active carriers (ACs) selection scheme in order to prevent
performance degradation in blind IFO estimation. The simulation
results show that under the AWGN and TU6 channels, the proposed
method has low complexity than conventional method and almost
similar performance in comparison with the conventional method.
Abstract: A complete spectral representation for the
electromagnetic field of planar multilayered waveguides
inhomogeneously filled with omega media is presented. The problem
of guided electromagnetic propagation is reduced to an eigenvalue
equation related to a 2 ´ 2 matrix differential operator. Using the
concept of adjoint waveguide, general bi-orthogonality relations for
the hybrid modes (either from the discrete or from the continuous
spectrum) are derived. For the special case of homogeneous layers
the linear operator formalism is reduced to a simple 2 ´ 2 coupling
matrix eigenvalue problem. Finally, as an example of application, the
surface and the radiation modes of a grounded omega slab waveguide
are analyzed.
Abstract: PPX(Pretty Printer for XML) is a query language that offers a concise description method of formatting the XML data into HTML. In this paper, we propose a simple specification of formatting method that is a combination description of automatic layout operators and variables in the layout expression of the GENERATE clause of PPX. This method can automatically format irregular XML data included in a part of XML with layout decision rule that is referred to DTD. In the experiment, a quick comparison shows that PPX requires far less description compared to XSLT or XQuery programs doing same tasks.
Abstract: In this study thermodynamic performance analysis of a
combined organic Rankine cycle and ejector refrigeration cycle is
carried out for use of low-grade heat source in the form of sensible
energy. Special attention is paid to the effects of system parameters
including the turbine inlet temperature and turbine inlet pressure on the
characteristics of the system such as ratios of mass flow rate, net work
production, and refrigeration capacity as well as the coefficient of
performance and exergy efficiency of the system. Results show that
for a given source the coefficient of performance increases with
increasing of the turbine inlet pressure. However, the exergy
efficiency has an optimal condition with respect to the turbine inlet
pressure.
Abstract: The present models and simulation algorithms of intracellular stochastic kinetics are usually based on the premise that diffusion is so fast that the concentrations of all the involved species are homogeneous in space. However, recents experimental measurements of intracellular diffusion constants indicate that the assumption of a homogeneous well-stirred cytosol is not necessarily valid even for small prokaryotic cells. In this work a mathematical treatment of diffusion that can be incorporated in a stochastic algorithm simulating the dynamics of a reaction-diffusion system is presented. The movement of a molecule A from a region i to a region j of the space is represented as a first order reaction Ai k- ! Aj , where the rate constant k depends on the diffusion coefficient. The diffusion coefficients are modeled as function of the local concentration of the solutes, their intrinsic viscosities, their frictional coefficients and the temperature of the system. The stochastic time evolution of the system is given by the occurrence of diffusion events and chemical reaction events. At each time step an event (reaction or diffusion) is selected from a probability distribution of waiting times determined by the intrinsic reaction kinetics and diffusion dynamics. To demonstrate the method the simulation results of the reaction-diffusion system of chaperoneassisted protein folding in cytoplasm are shown.
Abstract: Many footbridges have natural frequencies that
coincide with the dominant frequencies of the pedestrian-induced
load and therefore they have a potential to suffer excessive vibrations
under dynamic loads induced by pedestrians. Some of the design
standards introduce load models for pedestrian loads applicable for
simple structures. Load modeling for more complex structures, on the
other hand, is most often left to the designer. The main focus of this
paper is on the human induced forces transmitted to a footbridge and
on the ways these loads can be modeled to be used in the dynamic
design of footbridges. Also design criteria and load models proposed
by widely used standards were introduced and a comparison was
made. The dynamic analysis of the suspension bridge in Kolin in the
Czech Republic was performed on detailed FEM model using the
ANSYS program system. An attempt to model the load imposed by a
single person and a crowd of pedestrians resulted in displacements
and accelerations that are compared with serviceability criteria.