Local Dynamic Mechanical Properties of Native Porcine Endplate
Hysitron TriboIndenterTM TI 950 system has been
used for studying the local viscoelastic properties of porcine
intervertebral disc end plate by means of nanoscale mechanical
dynamic analysis. The specimen of an endplate was cut from fresh
porcine vertebra dissected from 16 month animal. The lumbar spine
motion segments were dissected and 5 millimeter thick plates of
vertebral body, endplate and annulus fibrosus were prepared for
nanoindentation. The surface of the sample was kept in physiological
solution during nanoindentation experiment. We obtained mechanical
characteristics of different areas of native endplate (endplate middle
and vertebra and annulus fibrosus boundary).
[1] URBAN, Jill PG; ROBERTS, Sally. Degeneration of intervertebral disc.
Arthritis Research & Therapy. 11 Mar 2003, No 3, s. 120-130.
[2] LOTZ, J. C., et al. Mechanobiology of the intervertebral disc.
Biomechanical Society. 2002, 30, s. 853-858.
[3] ROBERTS, S.; MENAGE, J.; URBAN, J. P. G. Biochemical and
Structural Properties of the Cartilage End-Plate and its Relation to the
Intervertebral Disc. Spine. 1989, 2, s. 166-74.
[4] Melrose, J., D. Burkhardt, T. K. F. Taylor, C. T. Dillon, R. Read, M.
Cake and C. B. Little, European Spine Journal, 18:479-489 (2009).
[5] BROCKBANK, Kelvin G. M., et al. Quantitative second harmonic
generation imaging of cartilage damage. Cell Tissue Banking. 2008, 9, s.
299-307.
[6] Asif, S. A. S., Wahl, K. J., Colton, R. J.: Review of Scientific
Instruments, 70, 5, 2408-2413 (1999).
[7] W. C., Pharr, G. M.: J. of Material Research, 7, 1564-1583 (1992).
[8] Sepitka, J., Lukes, Kuzelka, J., Reznicek, J.: Nanoscale dynamic
mechanical analysis of soft tissue and its finite element modeling.
Chemické Listy. DOPLNIT
[9] Lukes, J., Sepitka, J., Nemecek, J.: Dynamic nanoindentation of bovine
intervertebral end plate; Chemické Listy.104, 15, p. 338-341 (2010).
[1] URBAN, Jill PG; ROBERTS, Sally. Degeneration of intervertebral disc.
Arthritis Research & Therapy. 11 Mar 2003, No 3, s. 120-130.
[2] LOTZ, J. C., et al. Mechanobiology of the intervertebral disc.
Biomechanical Society. 2002, 30, s. 853-858.
[3] ROBERTS, S.; MENAGE, J.; URBAN, J. P. G. Biochemical and
Structural Properties of the Cartilage End-Plate and its Relation to the
Intervertebral Disc. Spine. 1989, 2, s. 166-74.
[4] Melrose, J., D. Burkhardt, T. K. F. Taylor, C. T. Dillon, R. Read, M.
Cake and C. B. Little, European Spine Journal, 18:479-489 (2009).
[5] BROCKBANK, Kelvin G. M., et al. Quantitative second harmonic
generation imaging of cartilage damage. Cell Tissue Banking. 2008, 9, s.
299-307.
[6] Asif, S. A. S., Wahl, K. J., Colton, R. J.: Review of Scientific
Instruments, 70, 5, 2408-2413 (1999).
[7] W. C., Pharr, G. M.: J. of Material Research, 7, 1564-1583 (1992).
[8] Sepitka, J., Lukes, Kuzelka, J., Reznicek, J.: Nanoscale dynamic
mechanical analysis of soft tissue and its finite element modeling.
Chemické Listy. DOPLNIT
[9] Lukes, J., Sepitka, J., Nemecek, J.: Dynamic nanoindentation of bovine
intervertebral end plate; Chemické Listy.104, 15, p. 338-341 (2010).
@article{"International Journal of Medical, Medicine and Health Sciences:56853", author = "J. Sepitka and J. Lukes and J. Reznicek", title = "Local Dynamic Mechanical Properties of Native Porcine Endplate", abstract = "Hysitron TriboIndenterTM TI 950 system has been
used for studying the local viscoelastic properties of porcine
intervertebral disc end plate by means of nanoscale mechanical
dynamic analysis. The specimen of an endplate was cut from fresh
porcine vertebra dissected from 16 month animal. The lumbar spine
motion segments were dissected and 5 millimeter thick plates of
vertebral body, endplate and annulus fibrosus were prepared for
nanoindentation. The surface of the sample was kept in physiological
solution during nanoindentation experiment. We obtained mechanical
characteristics of different areas of native endplate (endplate middle
and vertebra and annulus fibrosus boundary).", keywords = "nanoindentation, DMA, endplate, cartilage", volume = "5", number = "12", pages = "676-4", }