Characterization of HD-V2 Gafchromic Film for Measurement of Spatial Dose Distribution from Alpha Particle of 5.5 MeV
The purpose of this study was to investigate the
response of the newly released Gafchromic HD-V2 film for alpha
particle of 5.5 MeV. Gafchromic HD-V2 was exposed to alpha
particles of energy 5 MeV from 241Am for different durations. Then
the films were scanned with a flatbed scanner. The dose response
curve up to 2200 Gy has been achieved. The film’s reproducibility
and sensitivity were evaluated. The results obtained show that the net
optical density increases almost exponentially with the increase in the
exposure time, and it becomes saturated after prolonged exposure
times. The red channel shows the highest sensitivity, with a value of
4 x 10-3 Gy-1 at netOD of 0.4. The inter-film reproducibility was
measured and the relative uncertainty found was 1.7 %, 2.1 % and 2.3
% for grey, red and green channels, respectively.
<p>[1] D. Nikezic, A. K. M. M. Haque, and K. N. Yu, "Absorbed dose
delivered by alpha particles calculated in cylindrical geometry," Journal
of Environmental Radioactivity, vol. 60, pp. 293–305, 2002.
[2] S. A. Park, et al., "Dose verification of proton beam therapy using the
Gafchromic EBT film," Radiation Measurements, vol. 46, pp. 717-721,
2011.
[3] M. R. Zalutsky, et al., "Clinical Experience with a-Particle–Emitting
211At: Treatment of Recurrent Brain Tumor Patients with 211At-Labeled
Chimeric Antitenascin Monoclonal Antibody 81C6," THE JOURNAL
OF NUCLEAR MEDICINE, vol. 49, pp. 30-38, 2007.
[4] B. J. Allen, Z. Tian, S. M. A. Rizvi, Y. Li, and M. Ranson, "Preclinical
studies of targeted α therapy for breast cancer using 213Bi-labelledplasminogen
activator inhibitor type 2," British Journal of Cancer, vol.
88, pp. 944–950, 2003.
[5] J. C. Roeske, B. Aydogan, M. Bardies, and J. L. Humm, "Small-Scale
Dosimetry: Challenges and Future Directions," Semin Nucl Med, vol. 38,
pp. 367-383, 2008.
[6] M. W. Charles, "Skin dose from Ra-226 contamination: Dose estimation
& comments," unpublished.
[7] Ashland dosimetry systems, "GAFCHROMIC dosimetry media, type
HD-V2," ed, 2012.
[8] A. S. Aydarous, M. W. Charles, and P. J. Darley, "Dose distribution
measurements and calculations for Dounreay hot particles," Radiation
Protection Dosimetry, vol. 128, pp. 146-158, 2008.
[9] M. J. Schepis, et al., "Measurement of the sensitivity and spatial
resolution of radiochromic film using ion beams and X-rays," Submitted
for the DPP12 Meeting of The American Physical Society, 2013.
[10] A. Niroomand-Rad, et al., "Radiochromic film dosimetry:
recommendations of AAPM Radiation Therapy Committee Task Group
55," Med. Phys., vol. 25, 1998.
[11] A. S. Aydarous, P. J. Darley, and M. W. Charles, "A wide dynamic
range, high-spatial-resolution scanning system for radiochromic dye
films," Phys. Med. Biol., vol. 46, pp. 1379–1389, 2001.
[12] Slobodan Devic, et al., "Dosimetric properties of improved GafChromic
films for seven different digitizers," Med. Phys., vol. 31, pp. 2392-2401,
2004.
[13] J. Sorriaux, et al., "Evaluation of Gafchromic EBT3 films characteristics
in therapy photon, electron and proton beams," Physica Medica, vol. In
press, 2012.
[14] L. Wack, et al., "High throughput film dosimetry in homogeneous and
heterogeneous media for a small animal irradiator," Physica Medica,
vol. In press, 2013.
[15] M. J. Butsona, P. K. N. Yua, T. Cheunga, and P. Metcalfe,
"Radiochromic film for medical radiation dosimetry," Materials Science
and Engineering, vol. R 41, pp. 61-120, 2003.</p>
<p>[1] D. Nikezic, A. K. M. M. Haque, and K. N. Yu, "Absorbed dose
delivered by alpha particles calculated in cylindrical geometry," Journal
of Environmental Radioactivity, vol. 60, pp. 293–305, 2002.
[2] S. A. Park, et al., "Dose verification of proton beam therapy using the
Gafchromic EBT film," Radiation Measurements, vol. 46, pp. 717-721,
2011.
[3] M. R. Zalutsky, et al., "Clinical Experience with a-Particle–Emitting
211At: Treatment of Recurrent Brain Tumor Patients with 211At-Labeled
Chimeric Antitenascin Monoclonal Antibody 81C6," THE JOURNAL
OF NUCLEAR MEDICINE, vol. 49, pp. 30-38, 2007.
[4] B. J. Allen, Z. Tian, S. M. A. Rizvi, Y. Li, and M. Ranson, "Preclinical
studies of targeted α therapy for breast cancer using 213Bi-labelledplasminogen
activator inhibitor type 2," British Journal of Cancer, vol.
88, pp. 944–950, 2003.
[5] J. C. Roeske, B. Aydogan, M. Bardies, and J. L. Humm, "Small-Scale
Dosimetry: Challenges and Future Directions," Semin Nucl Med, vol. 38,
pp. 367-383, 2008.
[6] M. W. Charles, "Skin dose from Ra-226 contamination: Dose estimation
& comments," unpublished.
[7] Ashland dosimetry systems, "GAFCHROMIC dosimetry media, type
HD-V2," ed, 2012.
[8] A. S. Aydarous, M. W. Charles, and P. J. Darley, "Dose distribution
measurements and calculations for Dounreay hot particles," Radiation
Protection Dosimetry, vol. 128, pp. 146-158, 2008.
[9] M. J. Schepis, et al., "Measurement of the sensitivity and spatial
resolution of radiochromic film using ion beams and X-rays," Submitted
for the DPP12 Meeting of The American Physical Society, 2013.
[10] A. Niroomand-Rad, et al., "Radiochromic film dosimetry:
recommendations of AAPM Radiation Therapy Committee Task Group
55," Med. Phys., vol. 25, 1998.
[11] A. S. Aydarous, P. J. Darley, and M. W. Charles, "A wide dynamic
range, high-spatial-resolution scanning system for radiochromic dye
films," Phys. Med. Biol., vol. 46, pp. 1379–1389, 2001.
[12] Slobodan Devic, et al., "Dosimetric properties of improved GafChromic
films for seven different digitizers," Med. Phys., vol. 31, pp. 2392-2401,
2004.
[13] J. Sorriaux, et al., "Evaluation of Gafchromic EBT3 films characteristics
in therapy photon, electron and proton beams," Physica Medica, vol. In
press, 2012.
[14] L. Wack, et al., "High throughput film dosimetry in homogeneous and
heterogeneous media for a small animal irradiator," Physica Medica,
vol. In press, 2013.
[15] M. J. Butsona, P. K. N. Yua, T. Cheunga, and P. Metcalfe,
"Radiochromic film for medical radiation dosimetry," Materials Science
and Engineering, vol. R 41, pp. 61-120, 2003.</p>
@article{"International Journal of Engineering, Mathematical and Physical Sciences:50700", author = "A. Aydarous and M. El Ghazaly", title = "Characterization of HD-V2 Gafchromic Film for Measurement of Spatial Dose Distribution from Alpha Particle of 5.5 MeV", abstract = "The purpose of this study was to investigate the
response of the newly released Gafchromic HD-V2 film for alpha
particle of 5.5 MeV. Gafchromic HD-V2 was exposed to alpha
particles of energy 5 MeV from 241Am for different durations. Then
the films were scanned with a flatbed scanner. The dose response
curve up to 2200 Gy has been achieved. The film’s reproducibility
and sensitivity were evaluated. The results obtained show that the net
optical density increases almost exponentially with the increase in the
exposure time, and it becomes saturated after prolonged exposure
times. The red channel shows the highest sensitivity, with a value of
4 x 10-3 Gy-1 at netOD of 0.4. The inter-film reproducibility was
measured and the relative uncertainty found was 1.7 %, 2.1 % and 2.3
% for grey, red and green channels, respectively.
", keywords = "Alpha dosimetry, 241Am, Gafchromic film.", volume = "7", number = "7", pages = "1100-3", }
