An Experimental Design Approach to Determine Effects of The Operating Parameters on The Rate of Ru promoted Ir Carbonylation of Methanol
carbonylation of methanol in homogenous phase is
one of the major routesfor production of acetic acid. Amongst group
VIII metal catalysts used in this process iridium has displayed the
best capabilities. To investigate effect of operating parameters like:
temperature, pressure, methyl iodide, methyl acetate, iridium,
ruthenium, and water concentrations on the reaction rate,
experimental design for this system based upon central composite
design (CCD) was utilized. Statistical rate equation developed by this
method contained individual, interactions and curvature effects of
parameters on the reaction rate. The model with p-value less than
0.0001 and R2 values greater than 0.9; confirmeda satisfactory fitness
of the experimental and theoretical studies. In other words, the
developed model and experimental data obtained passed all
diagnostic tests establishing this model as a statistically significant.
[1] SRI Consulting, Process Economic Program, Methanol and Derivatives,
Vol 3, 2009.
[2] Noriyuki Yoneda, Satoru Kusano, Makoto Yasui, Peter Pujado, Steve
Wilcher. "Recent advances in processes and catalysts for the production
of acetic acid".Applied Catalysis A: General, volume: 221 (2001). pp:
253-265.
[3] Hua Jiang, Zhongyang Liu, Pinglai Pan, Guoqing Yuan,"A novel
supported catalyst for the carbonylation of methanol"Journal of
Molecular Catalysis A: Chemical. 148 (1999) 215-225.
[4] Glenn J. Sunley, Derrick J. Watson."High productivity methanol
carbonylation catalysis using iridium The CativaTM process for the
manufacture of acetic acid".Catalysis Today, Volume: 58 (2000). pp:
293-307.
[5] Christophe M. Thomas, Georg Suss-Fink." Ligand effects in the
rhodium-catalyzed carbonylation of methanol". Coordination Chemistry
Reviews. Volume: 243 (2003).pp: 125-142.
[6] Anthony Haynes, Peter M. Maitlis, George E. Morris, Glenn J. Sunley,
Harry Adams, Peter W. Badger, Craig M. Bowers, David B. Cook, Paul
I. P. Elliott, TalitGhaffar, Helena Green, Tim R. Griffin, Marc Payne,
Jean M. Pearson, Michael J. Taylor, Paul W. Vickers, and Rob J.
Watt."Promotion of iridium-catalyzed methanol carbonylation:
mechanistic studies of the cativa process". Journal of American
Chemical Society. Volume: 126(2004). pp: 2847-2861.
[7] R.L. Mason, R.F. Gunst, J.L. Hess, Statistical Design and Analysis of
Experiments with Applications to Engineering and Science, 2nd ed.,John
Wiley & Sons, USA, 2003.
[8] Zivorad R. Lazic, Design of Experiments in Chemical Engineering,
WILEY-VCHVerlag GmbH & Co. KGaA, Germany, 2004.
[9] C. Montgomery, Design and Analysis of Experiments, 4th ed., John
Wiley & Sons, USA, 1996.
[1] SRI Consulting, Process Economic Program, Methanol and Derivatives,
Vol 3, 2009.
[2] Noriyuki Yoneda, Satoru Kusano, Makoto Yasui, Peter Pujado, Steve
Wilcher. "Recent advances in processes and catalysts for the production
of acetic acid".Applied Catalysis A: General, volume: 221 (2001). pp:
253-265.
[3] Hua Jiang, Zhongyang Liu, Pinglai Pan, Guoqing Yuan,"A novel
supported catalyst for the carbonylation of methanol"Journal of
Molecular Catalysis A: Chemical. 148 (1999) 215-225.
[4] Glenn J. Sunley, Derrick J. Watson."High productivity methanol
carbonylation catalysis using iridium The CativaTM process for the
manufacture of acetic acid".Catalysis Today, Volume: 58 (2000). pp:
293-307.
[5] Christophe M. Thomas, Georg Suss-Fink." Ligand effects in the
rhodium-catalyzed carbonylation of methanol". Coordination Chemistry
Reviews. Volume: 243 (2003).pp: 125-142.
[6] Anthony Haynes, Peter M. Maitlis, George E. Morris, Glenn J. Sunley,
Harry Adams, Peter W. Badger, Craig M. Bowers, David B. Cook, Paul
I. P. Elliott, TalitGhaffar, Helena Green, Tim R. Griffin, Marc Payne,
Jean M. Pearson, Michael J. Taylor, Paul W. Vickers, and Rob J.
Watt."Promotion of iridium-catalyzed methanol carbonylation:
mechanistic studies of the cativa process". Journal of American
Chemical Society. Volume: 126(2004). pp: 2847-2861.
[7] R.L. Mason, R.F. Gunst, J.L. Hess, Statistical Design and Analysis of
Experiments with Applications to Engineering and Science, 2nd ed.,John
Wiley & Sons, USA, 2003.
[8] Zivorad R. Lazic, Design of Experiments in Chemical Engineering,
WILEY-VCHVerlag GmbH & Co. KGaA, Germany, 2004.
[9] C. Montgomery, Design and Analysis of Experiments, 4th ed., John
Wiley & Sons, USA, 1996.
@article{"International Journal of Chemical, Materials and Biomolecular Sciences:56375", author = "Vahid Hosseinpour and Mohammad Kazemini and Alireza Mohammadrezaee", title = "An Experimental Design Approach to Determine Effects of The Operating Parameters on The Rate of Ru promoted Ir Carbonylation of Methanol", abstract = "carbonylation of methanol in homogenous phase is
one of the major routesfor production of acetic acid. Amongst group
VIII metal catalysts used in this process iridium has displayed the
best capabilities. To investigate effect of operating parameters like:
temperature, pressure, methyl iodide, methyl acetate, iridium,
ruthenium, and water concentrations on the reaction rate,
experimental design for this system based upon central composite
design (CCD) was utilized. Statistical rate equation developed by this
method contained individual, interactions and curvature effects of
parameters on the reaction rate. The model with p-value less than
0.0001 and R2 values greater than 0.9; confirmeda satisfactory fitness
of the experimental and theoretical studies. In other words, the
developed model and experimental data obtained passed all
diagnostic tests establishing this model as a statistically significant.", keywords = "Acetic Acid,Carbonylation of Methanol, Central
Composite Design, Experimental Design, Iridium/Ruthenium", volume = "5", number = "1", pages = "54-6", }