Influence of Gas-Liquid Separator Design on Performance of Airlift Bioreactors
The performance of airlift bioreactors are closely related with their geometry, especially the gas-liquid separator design. In this study, the influence of the gas-liquid separator geometry on oxygen transfer and gas hold-up was evaluated in 10-L concentric-tube airlift bioreactor operating with distilled water and xanthan gum solution. The specific airflow rate (ɸAIR) exhibited the higher effect on the oxygen transfer coefficient (kLa) for both fluids. While the gas-liquid separator openness angle (α) and liquid volume fraction on the gas-liquid separator (VGLS) have presented opposite effects on oxygen mass transfer, they affected negatively the global gas hold-up of distilled water system. The best degassing zone geometry corresponded to a 90° openness angle with 10% of the liquid on it.
<p>[1] P. M. Kilonzo, A. Margaritis, M. A. Bergougnou, J. Yu, Y. Qin, “Effects of geometrical design on hydrodynamics and mass transfer characteristics of a rectangular-column airlift bioreactor”, Biochem Eng J, vol. 34, pp. 279-288, 2007.
[2] Y. Wei, W. Tiefeng, L. Malin, W. Zhanwen, “Bubble circulation regimes in a multi-stage internal-loop airlift reactor”, Chem Eng Sci, vol. 142, pp. 301-308, 2008.
[3] M. O. Cerri, A. C. Badino, “Oxygen transfer in three scales of concentric tube airlift bioreactors”, Biochem Eng Sci, vol. 51, pp. 40-47, 2010.
[4] J. C. Merchuk, N. Ladwa, A. Cameron, M. Bulmer, I. Berzin, A. M. Pickett, “Liquid flow and mixing in concentric tube air-lift reactors”, J Chem Tech Biotech, vol. 66, pp. 174-182, 1996.
[5] F. Gumery, F. Ein-Mozaffari, Y. Dahan, “Characteristics of local flow dynamics and macro-mixing in airlift column reactors for reliable design and scale-up”, Int J Chem React Eng, vol. 7, 2009.
[6] P. M. Kilonzo, A. Margaritis, M. A. Bergougnou, J. Yu, Y. Qin, “Influence of the baffle clearance design on hydrodynamics of a two-riser rectangular airlift reactor with inverse internal loop and expanded gas-liquid separator”, Chem Eng J, vol. 121, pp. 17-26, 2006.
[7] M. R. Mehrnia, B. Bonakdarpour, J. Towfighi, M. M. Akbarnejad, “Design and operational aspects of airlift bioreactors for petroleum biodesulfurization”, Environmental Progress, vol. 23, n. 3, pp. 206-214, 2004.
[8] M. R. Mehrnia, J. Towfighi, B. Bonakdarpour, M. M. Akbarnejad, “Influence of top-section design and draft tube height on the performance of airlift bioreactors containing water-in-oil microemulsion”, J Chem tech Biotech, vol. 79, pp. 260-267, 2004.
[9] J. Klein, A. A. Vicente, J. A. Teixeira, “Hydrodynamics of a three-phase airlift reactor with an enlarged separator – Application to high cell density systems”, Canadian J Chem Eng, vol. 81, pp. 433-443, 2003.
[10] J. Klein, S. Godos, O. Dolgos, J. Markos, “Effect of a gas-liquid separator on the hydrodynamics and circulation flow regimes in internal-loop airlift reactors”, J Chem Tech Biotech, vol. 76, pp. 516-524, 2001.
[11] D. C. Montgomery, Design and Analysis of Experiments. New York, 2001.
[12] Y. Chisti, Airlift bioreactors. Belfast, Elsevier Science Publishers Ltd., 1989.
[13] S. Aiba, A.E. Humphrey, F. Millis, Biochemical Engineering. Tokyo, University of Tokyo Press, 1973.
[14] J. C. Merchuk, N. Ladwa, A. Cameron, M. Bulmer, A. M. Pickett, “Concentric tube airlift reactors: effects of geometrical design on performance”, AIChE J, vol. 40, n. 7, pp. 1105-1117, 1994.</p>
<p> </p>
<p>[1] P. M. Kilonzo, A. Margaritis, M. A. Bergougnou, J. Yu, Y. Qin, “Effects of geometrical design on hydrodynamics and mass transfer characteristics of a rectangular-column airlift bioreactor”, Biochem Eng J, vol. 34, pp. 279-288, 2007.
[2] Y. Wei, W. Tiefeng, L. Malin, W. Zhanwen, “Bubble circulation regimes in a multi-stage internal-loop airlift reactor”, Chem Eng Sci, vol. 142, pp. 301-308, 2008.
[3] M. O. Cerri, A. C. Badino, “Oxygen transfer in three scales of concentric tube airlift bioreactors”, Biochem Eng Sci, vol. 51, pp. 40-47, 2010.
[4] J. C. Merchuk, N. Ladwa, A. Cameron, M. Bulmer, I. Berzin, A. M. Pickett, “Liquid flow and mixing in concentric tube air-lift reactors”, J Chem Tech Biotech, vol. 66, pp. 174-182, 1996.
[5] F. Gumery, F. Ein-Mozaffari, Y. Dahan, “Characteristics of local flow dynamics and macro-mixing in airlift column reactors for reliable design and scale-up”, Int J Chem React Eng, vol. 7, 2009.
[6] P. M. Kilonzo, A. Margaritis, M. A. Bergougnou, J. Yu, Y. Qin, “Influence of the baffle clearance design on hydrodynamics of a two-riser rectangular airlift reactor with inverse internal loop and expanded gas-liquid separator”, Chem Eng J, vol. 121, pp. 17-26, 2006.
[7] M. R. Mehrnia, B. Bonakdarpour, J. Towfighi, M. M. Akbarnejad, “Design and operational aspects of airlift bioreactors for petroleum biodesulfurization”, Environmental Progress, vol. 23, n. 3, pp. 206-214, 2004.
[8] M. R. Mehrnia, J. Towfighi, B. Bonakdarpour, M. M. Akbarnejad, “Influence of top-section design and draft tube height on the performance of airlift bioreactors containing water-in-oil microemulsion”, J Chem tech Biotech, vol. 79, pp. 260-267, 2004.
[9] J. Klein, A. A. Vicente, J. A. Teixeira, “Hydrodynamics of a three-phase airlift reactor with an enlarged separator – Application to high cell density systems”, Canadian J Chem Eng, vol. 81, pp. 433-443, 2003.
[10] J. Klein, S. Godos, O. Dolgos, J. Markos, “Effect of a gas-liquid separator on the hydrodynamics and circulation flow regimes in internal-loop airlift reactors”, J Chem Tech Biotech, vol. 76, pp. 516-524, 2001.
[11] D. C. Montgomery, Design and Analysis of Experiments. New York, 2001.
[12] Y. Chisti, Airlift bioreactors. Belfast, Elsevier Science Publishers Ltd., 1989.
[13] S. Aiba, A.E. Humphrey, F. Millis, Biochemical Engineering. Tokyo, University of Tokyo Press, 1973.
[14] J. C. Merchuk, N. Ladwa, A. Cameron, M. Bulmer, A. M. Pickett, “Concentric tube airlift reactors: effects of geometrical design on performance”, AIChE J, vol. 40, n. 7, pp. 1105-1117, 1994.</p>
<p> </p>
@article{"International Journal of Chemical, Materials and Biomolecular Sciences:65600", author = "Mateus N. Esperança and Marcel O. Cerri and Alberto C. Badino", title = "Influence of Gas-Liquid Separator Design on Performance of Airlift Bioreactors", abstract = "The performance of airlift bioreactors are closely related with their geometry, especially the gas-liquid separator design. In this study, the influence of the gas-liquid separator geometry on oxygen transfer and gas hold-up was evaluated in 10-L concentric-tube airlift bioreactor operating with distilled water and xanthan gum solution. The specific airflow rate (ɸAIR) exhibited the higher effect on the oxygen transfer coefficient (kLa) for both fluids. While the gas-liquid separator openness angle (α) and liquid volume fraction on the gas-liquid separator (VGLS) have presented opposite effects on oxygen mass transfer, they affected negatively the global gas hold-up of distilled water system. The best degassing zone geometry corresponded to a 90° openness angle with 10% of the liquid on it.
", keywords = "Airlift bioreactor, gas holdup, gas-liquid separator, oxygen transfer. ", volume = "7", number = "11", pages = "840-5", }
