Efficient Preparation and Characterization of Carbohydrate Based Monomers. D-mannose Derivatives

The field of polymeric biomaterials is very important from the socio-economical viewpoint. Synthetic carbohydrate polymers are being increasingly investigated as biodegradable, biocompatible and biorenewable materials. The aim of this study was to synthesize and characterize some derivatives based on D-mannose. D-mannose was chemically modified to obtain 1-O-allyl-2,3:5,6-di- O-isopropylidene-D-mannofuranose and 1-O-(2-,3--epoxy-propyl)- 2,3:5,6-di-O-isopropylidene-D-mannofuranose. The chemical structure of the resulting compounds was characterized by FT-IR and NMR spectroscopy, and by HPLC-MS.

Authors:

• L. M. Stefan
• A. M. Pana
• M. Silion
• M. Balan
• G. Bandur
• L. M. Rusnac

Keywords:

• D-mannose
• biopolymers
• spectroscopy
• synthesis.

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