Determination of Myocardial Function Using Heart Accumulated Radiopharmaceuticals
The myocardium is composed of specialized muscle
which relies mainly on fatty acid and sugar metabolism and it is
widely contribute to the heart functioning. The changes of the cardiac
energy-producing system during heart failure have been proved using
autoradiography techniques. This study focused on evaluating sugar
and fatty acid metabolism in myocardium as cardiac energy getting
system using heart-accumulated radiopharmaceuticals. Two sets of
autoradiographs of heart cross sections of Lewis male rats were
analyzed and the time- accumulation curve obtained with use of the
MATLAB image processing software to evaluate fatty acid and sugar
metabolic functions.
[1] A. Waugh, A. Grant, “Anatomy and Physiology in Health and
Illness’’.9th ed. 2004, pp.82-87.
[2] J. Gerard ,T.B. Derrickson,“Principles of Anatomy & Physiology”.11th
ed. John Wiley & Sons, 2000-2013, pp. 698-713
[3] K. L. Zieler, “Fatty acids as substrates for heart and skeletal
muscle”.1976, Cric Res 38, pp. 459-463
[4] J. Marin-Garcia, “Mitochondria and Their Role in Cardiovascular
Disease”. Springer, 2012, pp. 3-9
[5] R. E. Eckart, S.L. Scoville, C.L. Campbell, E.A.Shry, K.C. Stajduhar, R.
N. Potter, L.A. Pearse and R. Virmani,“Sudden death in young adults: a
25-year review of autopsies in military recruits”. Ann Intern. Med, 2004.
141 (11), pp. 829–34.
[6] P. Bertram, Z.Faiez, “The Detection of Myocardial Fibrosis-An
Opportunity to Reduce Cardiovascular Risk in Patients with Diabetes
Mellitus?”. Jan 2012, 5(1), pp. 9-11
[1] A. Waugh, A. Grant, “Anatomy and Physiology in Health and
Illness’’.9th ed. 2004, pp.82-87.
[2] J. Gerard ,T.B. Derrickson,“Principles of Anatomy & Physiology”.11th
ed. John Wiley & Sons, 2000-2013, pp. 698-713
[3] K. L. Zieler, “Fatty acids as substrates for heart and skeletal
muscle”.1976, Cric Res 38, pp. 459-463
[4] J. Marin-Garcia, “Mitochondria and Their Role in Cardiovascular
Disease”. Springer, 2012, pp. 3-9
[5] R. E. Eckart, S.L. Scoville, C.L. Campbell, E.A.Shry, K.C. Stajduhar, R.
N. Potter, L.A. Pearse and R. Virmani,“Sudden death in young adults: a
25-year review of autopsies in military recruits”. Ann Intern. Med, 2004.
141 (11), pp. 829–34.
[6] P. Bertram, Z.Faiez, “The Detection of Myocardial Fibrosis-An
Opportunity to Reduce Cardiovascular Risk in Patients with Diabetes
Mellitus?”. Jan 2012, 5(1), pp. 9-11
@article{"International Journal of Medical, Medicine and Health Sciences:71579", author = "C. C. D. Kulathilake and M. Jayatilake and T. Takahashi", title = "Determination of Myocardial Function Using Heart Accumulated Radiopharmaceuticals", abstract = "The myocardium is composed of specialized muscle
which relies mainly on fatty acid and sugar metabolism and it is
widely contribute to the heart functioning. The changes of the cardiac
energy-producing system during heart failure have been proved using
autoradiography techniques. This study focused on evaluating sugar
and fatty acid metabolism in myocardium as cardiac energy getting
system using heart-accumulated radiopharmaceuticals. Two sets of
autoradiographs of heart cross sections of Lewis male rats were
analyzed and the time- accumulation curve obtained with use of the
MATLAB image processing software to evaluate fatty acid and sugar
metabolic functions.", keywords = "Autoradiographs, fatty acid, radiopharmaceuticals
and sugar.", volume = "9", number = "12", pages = "859-4", }