Bioceramic Scaffolds Fabrication by Rapid Prototyping Technology
This paper describes a rapid prototyping (RP)
technology for forming a hydroxyapatite (HA) bone scaffold model.
The HA powder and a silica sol are mixed into bioceramic slurry form
under a suitable viscosity. The HA particles are embedded in the
solidified silica matrix to form green parts via a wide range of process
parameters after processing by selective laser sintering (SLS). The
results indicate that the proposed process was possible to fabricate
multilayers and hollow shell structure with brittle property but
sufficient integrity for handling prior to post-processing. The
fabricated bone scaffold models had a surface finish of 25
[1] K. Xiao, K.W. Dalgarno, D.J. Wood, R.D. Goodridge, and C. Ohtsuki,
Indirect selective laser sintering of apatite-wollostonie glass-ceramic,
Journal of Engineering in Medicine, Vol. 222, 2008, pp.1107-1114.
[2] P. Vincenzini, Mater. Sci. Monogr, Vol. 17, 1983, pp. 3.
[3] L.A. Cyster, D.M. Grant, The influence of dispersant concentration on the
pore morphology of hydroxyapatite ceramics for bone tissue engineering,
Biomaterials, Vol. 26, No. 7, 2005, pp.697-702.
[4] A. Almirall, G. Larrecq, Fabrication of low temperature macroporous
hydroxyapatite scaffolds by forming and hydrolysis of a TCP paste,
Biomaterials, Vol. 25, No. 17, 2004, pp.3671-3680.
[5] J.C. Lorrison, K.W. Dalgarno, D.J. Wood, Processing of an
apatite-mullite galss-ceramic and an hydroxyapatite/ phosphate glass
composite by selective laser sintering, Journal of Materials Science:
Materials in Medicine, Vol. 16, 2005, pp.775-781.
[6] S.F. Yang, K.E. Leong, Z.H. Du, and C.K. Chua, The design of scaffolds
for use in tissue engineering, Part Ι: Traditional factors, Tissue
Engineering, Vol.7, 2001, pp.679-689.
[7] F.H. Liu, Y.K. Shen, Y.S. Liao, Selective laser gelation of ceramic-matrix
composites, Composite Part B: Engineering, Vol. 42, 2011, pp.57-61.
[8] F.H. Liu and Y.S. Liao, Fabrication inner complex ceramic part by
selective laser gelling, Journal of the European Ceramic Society, Vol. 30,
2010, pp. 3283-3289.
[9] M.J. Gauthier, E. Bouler, E. Arguado, P. Pilet, and G. Daculsi,
Macroporous biphasic calcium phosphate ceramic: influence of
macropore diameter and macroporosity percentage on bone ingrowth,
Biomaterials, Vol. 19, 1998, pp. 133-139.
[1] K. Xiao, K.W. Dalgarno, D.J. Wood, R.D. Goodridge, and C. Ohtsuki,
Indirect selective laser sintering of apatite-wollostonie glass-ceramic,
Journal of Engineering in Medicine, Vol. 222, 2008, pp.1107-1114.
[2] P. Vincenzini, Mater. Sci. Monogr, Vol. 17, 1983, pp. 3.
[3] L.A. Cyster, D.M. Grant, The influence of dispersant concentration on the
pore morphology of hydroxyapatite ceramics for bone tissue engineering,
Biomaterials, Vol. 26, No. 7, 2005, pp.697-702.
[4] A. Almirall, G. Larrecq, Fabrication of low temperature macroporous
hydroxyapatite scaffolds by forming and hydrolysis of a TCP paste,
Biomaterials, Vol. 25, No. 17, 2004, pp.3671-3680.
[5] J.C. Lorrison, K.W. Dalgarno, D.J. Wood, Processing of an
apatite-mullite galss-ceramic and an hydroxyapatite/ phosphate glass
composite by selective laser sintering, Journal of Materials Science:
Materials in Medicine, Vol. 16, 2005, pp.775-781.
[6] S.F. Yang, K.E. Leong, Z.H. Du, and C.K. Chua, The design of scaffolds
for use in tissue engineering, Part Ι: Traditional factors, Tissue
Engineering, Vol.7, 2001, pp.679-689.
[7] F.H. Liu, Y.K. Shen, Y.S. Liao, Selective laser gelation of ceramic-matrix
composites, Composite Part B: Engineering, Vol. 42, 2011, pp.57-61.
[8] F.H. Liu and Y.S. Liao, Fabrication inner complex ceramic part by
selective laser gelling, Journal of the European Ceramic Society, Vol. 30,
2010, pp. 3283-3289.
[9] M.J. Gauthier, E. Bouler, E. Arguado, P. Pilet, and G. Daculsi,
Macroporous biphasic calcium phosphate ceramic: influence of
macropore diameter and macroporosity percentage on bone ingrowth,
Biomaterials, Vol. 19, 1998, pp. 133-139.
@article{"International Journal of Mechanical, Industrial and Aerospace Sciences:64588", author = "F.H. Liu and S.H. Chen and R.T. Lee and W.S. Lin and Y.S. Liao", title = "Bioceramic Scaffolds Fabrication by Rapid Prototyping Technology", abstract = "This paper describes a rapid prototyping (RP)
technology for forming a hydroxyapatite (HA) bone scaffold model.
The HA powder and a silica sol are mixed into bioceramic slurry form
under a suitable viscosity. The HA particles are embedded in the
solidified silica matrix to form green parts via a wide range of process
parameters after processing by selective laser sintering (SLS). The
results indicate that the proposed process was possible to fabricate
multilayers and hollow shell structure with brittle property but
sufficient integrity for handling prior to post-processing. The
fabricated bone scaffold models had a surface finish of 25 ", keywords = "bioceramic, bone scaffold, rapid prototyping,selective laser sintering", volume = "5", number = "4", pages = "881-3", }