Abstract: Even the behavior problems in pre-school children might be considered as a transitional problem which may disappear by their transition into elementary school; it is an issue that needs a lot of attention because of the fact that the behavioral patterns are adopted in the children especially in this age. Common issue in the process of elimination of the behavior problems in the group of pre-school children is a difference in the perception of the importance and gravity of the symptoms. The underestimation of the children's problems by parents often result into conflicts with kindergarten teachers. Thus, the child does not get the support that his/her problems require and this might result into a school failure and can negatively influence his/her future school performance and success. The research sample consisted of 4 children with behavior problems, their teachers and parents. To determine the most problematic area in the child's behavior, Child Behavior Checklist (CBCL) filled by parents and Caregiver/Teacher Form (CTF-R) filled by teachers were used. Scores from the CBCL and the CTR-F were compared with Pearson correlation coefficient in order to find the differences in the perception of behavior problems in pre-school children.
Abstract: Neurological disorders are the most debilitating of manifestations seen in patients infected with HIV. The clinical profile of neurological manifestations in HIV patients has undergone a shift in recent years with opportunistic infections being controlled with combination anti-retroviral therapy and the advent of drugs which have higher central nervous system penetrability. The aim of this paper is to study the clinical, investigation profile and various neurological disorders in HIV patients on anti‐retroviral therapy. Fifty HIV patients with neurological manifestations were studied. A complete neurological examination including neurocognitive functioning using Montreal Cognitive Assessment and HIV Dementia scale were assessed. Apart from relevant investigations, CD4 count, cerebrovascular fluid analysis, computed tomography (CT) and magnetic resonance imaging (MRI) of brain were done whenever required. Neurocognitive disorders formed the largest group with 42% suffering from HIV associated Neurocognitive Disorders. Among them, asymptomatic neurocognitive impairment was seen in 28%; mild neurocognitive disorder in 12%, and 2% had HIV‐associated dementia. Opportunistic infections of the nervous system accounted for 32%, with meningitis being the most common. Four patients had space occupying lesions of central nervous system; four tuberculomas, and one toxoplasmosis. With the advent of highly active retroviral therapy, HIV patients have longer life spans with suppression of viral load leading to decrease in opportunistic infections of the nervous system. Neurocognitive disorders are now the most common neurological dysfunction seen and thus neurocognitive assessment must be done in all patients with HIV.
Abstract: The development of web technologies and mobile devices makes creating, accessing, using and sharing information or communicating with each other simpler every day. However, while the amount of information constantly increasing it is becoming harder to effectively organize and find quality information despite the availability of web search engines, filtering and indexing tools. Although digital technologies have overall positive impact on students’ lives, frequent use of these technologies and digital media enriched with dynamic hypertext and hypermedia content, as well as multitasking, distractions caused by notifications, calls or messages; can decrease the attention span, make thinking, memorizing and learning more difficult, which can lead to stress and mental exhaustion. This is referred to as “information overload”, “information glut” or “information anxiety”. Objective of this study is to determine whether students show signs of information overload and to identify the possible predictors. Research was conducted using a questionnaire developed for the purpose of this study. The results show that students frequently use technology (computers, gadgets and digital media), while they show moderate level of information literacy. They have sometimes experienced symptoms of information overload. According to the statistical analysis, higher frequency of technology use and lower level of information literacy are correlated with larger information overload. The multiple regression analysis has confirmed that the combination of these two independent variables has statistically significant predictive capacity for information overload. Therefore, the information science teachers should pay attention to improving the level of students’ information literacy and educate them about the risks of excessive technology use.
Abstract: The overarching aim of this study is to develop a soft-computing system for the differential diagnosis of tropical diseases. These conditions are of concern to health bodies, physicians, and the community at large because of their mortality rates, and difficulties in early diagnosis due to the fact that they present with symptoms that overlap, and thus become ‘confusable’. We report on the first phase of our study, which focuses on the development of a fuzzy cognitive map model for early differential diagnosis of tropical diseases. We used malaria as a case disease to show the effectiveness of the FCM technology as an aid to the medical practitioner in the diagnosis of tropical diseases. Our model takes cognizance of manifested symptoms and other non-clinical factors that could contribute to symptoms manifestations. Our model showed 85% accuracy in diagnosis, as against the physicians’ initial hypothesis, which stood at 55% accuracy. It is expected that the next stage of our study will provide a multi-disease, multi-symptom model that also improves efficiency by utilizing a decision support filter that works on an algorithm, which mimics the physician’s diagnosis process.
Abstract: Background: Plantar pressure measurement is an effective method for assessing plantar loading and can be applied to evaluating movement performance of the foot. The purpose of this study is to explore the sprint athletes’ plantar loading characteristics and pain profiles in static standing. Methods: Experiments were undertaken on 80 first-division college sprint athletes and 85 healthy non-sprinters. ‘JC Mat’, the optical plantar pressure measurement was applied to examining the differences between both groups in the arch index (AI), three regional and six distinct sub-regional plantar pressure distributions (PPD), and footprint characteristics. Pain assessment and self-reported health status in sprint athletes were examined for evaluating their common pain areas. Results: Findings from the control group, the males’ AI fell into the normal range. Yet, the females’ AI was classified as the high-arch type. AI values of the sprint group were found to be significantly lower than the control group. PPD were higher at the medial metatarsal bone of both feet and the lateral heel of the right foot in the sprint group, the males in particular, whereas lower at the medial and lateral longitudinal arches of both feet. Footprint characteristics tended to support the results of the AI and PPD, and this reflected the corresponding pressure profiles. For the sprint athletes, the lateral knee joint and biceps femoris were the most common musculoskeletal pains. Conclusions: The sprint athletes’ AI were generally classified as high arches, and that their PPD were categorized between the features of runners and high-arched runners. These findings also correspond to the profiles of patellofemoral pain syndrome (PFPS)-related plantar pressure. The pain profiles appeared to correspond to the symptoms of high-arched runners and PFPS. The findings reflected upon the possible link between high arches and PFPS. The correlation between high-arched runners and PFPS development is worth further studies.
Abstract: Recently, the world main problem is a global warming and climate change affecting both outdoor and indoor environments, especially the air quality (AQ) as a result of vast migration of people from rural areas to urban areas. Therefore, cities became more crowded and denser from an irregular population increase, along with increasing urbanization caused many problems for the environment such as increasing the land prices, changes in life style, and the new buildings are not adapted to the climate producing uncomfortable and unhealthy indoor building conditions. As interior environments are the places that create the most intimate relationship with the user. Consequently, the indoor environment quality (IEQ) for buildings became uncomfortable and unhealthy for its occupants. The symptoms commonly associated with poor indoor environment such as itchy, headache, fatigue, and respiratory complaints such as cough and congestion, etc. The symptoms tend to improve over time or even disappear when people are away from the building. Therefore, designing a healthy indoor environment to fulfill human needs is the main concern for architects and interior designer. However, this research explores how occupant expectations and environmental attitudes may influence occupant health and satisfaction within the context of the indoor environment. In doing so, it reviews and contributes to the methods and tools used to evaluate only the indoor environment quality (IEQ) components of building performance. Its main aim is to review the literature on indoor human comfort. This is followed by a review of previous papers published related to human comfort. Finally, this paper will provide possible approaches in design level of healthy buildings.
Abstract: Purpose: The key aim of the research was to identify
the secondary stressors experienced by businesses affected by single
or repeated flooding and to determine to what extent businesses were
affected by these stressors, along with any resulting impact on health.
Additionally the research aimed to establish the likelihood of
businesses being re-exposed to the secondary stressors through
assessing awareness of flood risk, implementation of property
protection measures and level of community resilience. Design/methodology/approach: The chosen research method
involved the distribution of a questionnaire survey to businesses
affected by either single or repeated flood events. The questionnaire
included the Impact of Event Scale (a 15-item self-report measure
which assesses subjective distress caused by traumatic events). Findings: 55 completed questionnaires were returned by flood
impacted businesses. 89% of the businesses had sustained internal
flooding, while 11% had experienced external flooding. The results
established that the key secondary stressors experienced by
businesses, in order of priority, were: flood damage, fear of
reoccurring flooding, prevention of access to the premise/closure,
loss of income, repair works, length of closure and insurance issues.
There was a lack of preparedness for potential future floods and
consequent vulnerability to the emergence of secondary stressors
among flood affected businesses, as flood resistance or flood
resilience measures had only been implemented by 11% and 13%
respectively. In relation to the psychological repercussions, the
Impact of Event scores suggested that potential prevalence of posttraumatic
stress disorder (PTSD) was noted among 8 out of 55
respondents (l5%). Originality/value: The results improve understanding of the
enduring repercussions of flood events on businesses, indicating that
not only residents may be susceptible to the detrimental health
impacts of flood events and single flood events may be just as likely
as reoccurring flooding to contribute to ongoing stress. Lack of
financial resources is a possible explanation for the lack of
implementation of property protection measures among businesses,
despite 49% experiencing flooding on multiple occasions. Therefore
it is recommended that policymakers should consider potential
sources of financial support or grants towards flood defences for
flood impacted businesses. Any form of assistance should be made
available to businesses at the earliest opportunity as there was no
significant association between the time of the last flood event and
the likelihood of experiencing PTSD symptoms.
Abstract: In recent years, the power system has been changed
and a flexible power pricing system such as demand response has been
sought in Japan. The demand response system works simply in the
household sector and the owner as the decision-maker, can benefit
from power saving. On the other hand, the execution of demand
response in the office building is more complex than in the household
because various people such as owners, building administrators and
occupants are involved in the decision-making process. While the
owners benefit from demand saving, the occupants are exposed to
restricted benefits of a demand-saved environment. One of the reasons
is that building systems are usually under centralized management and
each occupant cannot choose freely whether to participate in demand
response or not. In addition, it is unclear whether incentives give
occupants the motivation to participate. However, the recent
development of IT and building systems enables the personalized
control of the office environment where each occupant can control the
lighting level or temperature individually. Therefore, it can be possible
to have a system which each occupant can make a decision of whether
or not to participate in demand response in the office building. This study investigates personal responses to demand response
requests, under the condition where each occupant can adjust their
brightness individually in their workspace. Once workers participate
in the demand response, their desk-lights are automatically turned off.
The participation rates in the demand response events are compared
among four groups, which are divided by different motivation, the
presence, or absence of incentives and the method of participation. The
result shows that there are significant differences of participation rates
in demand response event between four groups. The method of
participation has a large effect on the participation rate. The “Opt-out”
groups where the occupants are automatically enrolled in a demand
response event if they do not express non-participation have the
highest participation rate in the four groups. Incentives also have an
effect on the participation rate. This study also reports on the impact of low illumination office
environment on the occupants, such as stress or fatigue. The
electrocardiogram and the questionnaire are used to investigate the
autonomic nervous activity and subjective fatigue symptoms of the
occupants. There is no big difference between dim workspace during
demand response event and bright workspace in autonomic nervous
activity and fatigue.
Abstract: Myocardial infarction is one of the leading causes of
death in the world. Some of these deaths occur even before the
patient reaches the hospital. Myocardial infarction occurs as a result
of impaired blood supply. Because the most of these deaths are due to
coronary artery disease, hence the awareness of the warning signs of
a heart attack is essential. Some heart attacks are sudden and intense,
but most of them start slowly, with mild pain or discomfort, then
early detection and successful treatment of these symptoms is vital to
save them. Therefore, importance and usefulness of a system
designing to assist physicians in early diagnosis of the acute heart
attacks is obvious. The main purpose of this study would be to enable patients to
become better informed about their condition and to encourage them
to seek professional care at an earlier stage in the appropriate
situations. For this purpose, the data were collected on 711 heart
patients in Iran hospitals. 28 attributes of clinical factors can be
reported by patients; were studied. Three logistic regression models
were made on the basis of the 28 features to predict the risk of heart
attacks. The best logistic regression model in terms of performance
had a C-index of 0.955 and with an accuracy of 94.9%. The variables,
severe chest pain, back pain, cold sweats, shortness of breath, nausea
and vomiting, were selected as the main features.
Abstract: Cortisol is essential to the regulation of the immune
system and pathological yawning is a symptom of multiple sclerosis
(MS). Electromyography activity (EMG) in the jaw muscles typically
rises when the muscles are moved – extended or flexed; and yawning
has been shown to be highly correlated with cortisol levels in healthy
people as shown in the Thompson Cortisol Hypothesis. It is likely
that these elevated cortisol levels are also seen in people with MS.
The possible link between EMG in the jaw muscles and rises in saliva
cortisol levels during yawning were investigated in a randomized
controlled trial of 60 volunteers aged 18-69 years who were exposed
to conditions that were designed to elicit the yawning response.
Saliva samples were collected at the start and after yawning, or at the
end of the presentation of yawning-provoking stimuli, in the absence
of a yawn, and EMG data was additionally collected during rest and
yawning phases. Hospital Anxiety and Depression Scale, Yawning
Susceptibility Scale, General Health Questionnaire, demographic,
and health details were collected and the following exclusion criteria
were adopted: chronic fatigue, diabetes, fibromyalgia, heart
condition, high blood pressure, hormone replacement therapy,
multiple sclerosis, and stroke. Significant differences were found
between the saliva cortisol samples for the yawners, t (23) = -4.263, p
= 0.000, as compared with the non-yawners between rest and poststimuli,
which was non-significant. There were also significant
differences between yawners and non-yawners for the EMG
potentials with the yawners having higher rest and post-yawning
potentials. Significant evidence was found to support the Thompson
Cortisol Hypothesis suggesting that rises in cortisol levels are
associated with the yawning response. Further research is underway
to explore the use of cortisol as a potential diagnostic tool as an assist
to the early diagnosis of symptoms related to neurological disorders.
Bournemouth University Research & Ethics approval granted:
JC28/1/13-KA6/9/13. Professional code of conduct, confidentiality,
and safety issues have been addressed and approved in the Ethics
submission. Trials identification number: ISRCTN61942768.
http://www.controlled-trials.com/isrctn/
Abstract: An analytical 4-DOF nonlinear model of a de Laval
rotor-stator system based on Energy Principles has been used
theoretically and experimentally to investigate fault symptoms in a
rotating system. The faults, namely rotor-stator-rub, crack and
unbalance are modeled as excitations on the rotor shaft. Mayes
steering function is used to simulate the breathing behaviour of the
crack. The fault analysis technique is based on waveform signal,
orbits and Fast Fourier Transform (FFT) derived from simulated and
real measured signals. Simulated and experimental results manifest
considerable mutual resemblance of elliptic-shaped orbits and FFT
for a same range of test data.
Abstract: The present study aimed to determine the
effectiveness of Metaphor therapy on depression among female
students. The sample included 60 female students with depression
symptoms selected by simple sampling and randomly divided into
two equal groups (experimental and control groups). Beck
Depression Inventory was used to measure the variables. This was an
experimental study with a pre-test/post-test design with control
group. Eight metaphor therapy sessions were held for the
experimental group. A post-test was administered to both groups.
Data were analyzed using multivariate analysis of covariance
(MANCOVA). Results showed that the Metaphor therapy decreased
depression in the experimental group compared to the control group.
Abstract: The current paper presents the results of a conducted
case study. During the past few years the number of children
diagnosed with Learning Difficulties has drastically augmented and
especially the cases of ADHD (Attention Deficit Hyperactivity
Disorder). One of the core characteristics of ADHD is a deficit in
working memory functions. The review of the literature indicates a
plethora of educational software that aim at training and enhancing
the working memory. Nevertheless, in the current paper, the
possibility of using for the same purpose free, online games will be
explored. Another issue of interest is the potential effect of the
working memory training to the core symptoms of ADHD. In order
to explore the abovementioned research questions, three digital tests
are employed, all of which are developed on the E-slate platform by
the author, in order to check the levels of ADHD’s symptoms and to
be used as diagnostic tools, both in the beginning and in the end of
the case study. The tools used during the main intervention of the
research are free online games for the training of working memory.
The research and the data analysis focus on the following axes: a) the
presence and the possible change in two of the core symptoms of
ADHD, attention and impulsivity and b) a possible change in the
general cognitive abilities of the individual. The case study was
conducted with the participation of a thirteen year-old, female
student, diagnosed with ADHD, during after-school hours. The
results of the study indicate positive changes both in the levels of
attention and impulsivity. Therefore, we conclude that the training of
working memory through the use of free, online games has a positive
impact on the characteristics of ADHD. Finally, concerning the
second research question, the change in general cognitive abilities, no
significant changes were noted.
Abstract: Numerous investigations suggest that Mesenchymal
Stem Cells (MSCs) in general represent a valuable tool for therapy of
symptoms related to chronic inflammatory diseases. Blue Horizon
Stem Cell Therapy Program is a leading provider of adult and
children’s stem cell therapies. Uniquely we have safely and
efficiently treated more than 600 patients with documenting each
procedure. The purpose of our study is primarily to monitor the
immune response in order to validate the safety of intravenous
infusion of human umbilical cord blood derived MSCs (UC-MSCs),
and secondly, to evaluate effects on biomarkers associated with
chronic inflammation. Nine patients were treated for conditions
associated with chronic inflammation and for the purpose of antiaging.
They have been given one intravenous infusion of UCMSCs.
Our study of blood test markers of 9 patients with chronic
inflammation before and within three months after MSCs treatment
demonstrates that there is no significant changes and MSCs treatment
was safe for the patients. Analysis of different indicators of chronic
inflammation and aging included in initial, 24-hours, two weeks and
three months protocols showed that stem cell treatment was safe for
the patients; there were no adverse reactions. Moreover data from
follow up protocols demonstrates significant improvement in energy
level, hair, nails growth and skin conditions. Intravenously
administered UC-MSCs were safe and effective in the improvement
of symptoms related to chronic inflammation. Further close
monitoring and inclusion of more patients are necessary to fully
characterize the advantages of UC-MSCs application in treatment of
symptoms related to chronic inflammation.
Abstract: Background: Diabetic sensorimotor polyneuropathy
(DSP) is one of the most common microvascular complications of
type 2 diabetes. Loss of sensation is thought to contribute to a lack of
static and dynamic stability and increased risk of falling. Purpose:
The purpose of this study was to compare the effects of low-level
laser (LLL) and monochromatic near-infrared photo energy (MIRE)
on pain, cutaneous sensation, static stability, and index of lower limb
blood flow in diabetic patients with peripheral neuropathy. Methods:
Forty diabetic patients with peripheral neuropathy were recruited for
participation in this study. They were divided into two groups: The
MIRE group, which contained 20 patients, and the LLL group, which
contained 20 patients. All patients who participated in the study had
been subjected to various physical assessment procedures, including
pain, cutaneous sensation, Doppler flow meter, and static stability
assessments. The baseline measurements were followed by treatment
sessions that were conducted twice a week for six successive weeks.
Results: The statistical analysis of the data revealed significant
improvement of pain in both groups, with significant improvement in
cutaneous sensation and static balance in the MIRE group compared
to the LLL group; on the other hand, the results showed no
significant differences in lower limb blood flow between the groups.
Conclusion: LLL and MIRE can improve painful symptoms in
patients with diabetic neuropathy. On the other hand, MIRE is also
useful in improving cutaneous sensation and static stability in
patients with diabetic neuropathy.
Abstract: This paper is based on a large questionnaire study. The
paper presents how all participants and subgroups (upper- and
lower-level white-collar workers) answered the question, “Have you
had an ache, pain, or numbness, which you associate with desktop
computer use, in the different body parts during the last 12 months?’
14.6% of participants (19.4% of women and 8.2% of men) reported
that they had often or very often physical symptoms in the neck. Even
if our results cannot prove a causal relation of symptoms with
computer use, show that workers believe that computer use can
influence their wellbeing: this is important when devising treatment
modalities to decrease these physical symptoms.
Abstract: Background: Delayed onset muscle soreness (DOMS)
is the most common symptom when ordinary individuals and athletes
are exposed to unaccustomed physical activity, especially eccentric
contraction which impairs athletic performance, ordinary people
work ability and physical functioning. Multitudes of methods have
been investigated to reduce DOMS. One of the valuable methods to
control DOMS is repeated bout effect (RBE) as a prophylactic
method. Purpose: To compare the repeated bout effect of
submaximal eccentric with maximal isometric contraction on induced
DOMS. Methods: Sixty normal male volunteers were assigned
randomly into three equal groups: Group A (first study group): 20
subjects received submaximal eccentric contraction on non-dominant
elbow flexors as a prophylactic exercise. Group B (second study
group): 20 subjects received maximal isometric contraction on nondominant
elbow flexors as a prophylactic exercise. Group C (control
group): 20 subjects did not receive any prophylactic exercises.
Maximal isometric peak torque of elbow flexors and patient related
elbow evaluation (PREE) scale were measured for each subject 3
times before, immediately after, and 48 hours after induction of
DOMS. Results: Post-hoc test for maximal isometric peak torque and
PREE scale immediately and 48 hours after induction of DOMS
revealed that group (A) and group (B) resulted in significant decrease
in maximal isometric strength loss and elbow pain and disability
rather than control group (C), but submaximal eccentric group (A)
was more effective than maximal isometric group (B) as it showed
more rapid recovery of functional strength and less degrees of elbow
pain and disability. Conclusion: Both submaximal eccentric
contraction and maximal isometric contraction were effective in
prevention of DOMS but submaximal eccentric contraction produced
a greater protective effect against muscle damage induced by
maximal eccentric exercise performed 2 days later.
Abstract: When neck pain is associated with pain, numbness, or
weakness in the arm, shoulder, or hand, further investigation is
needed as these are symptoms indicating pressure on one or more
nerve roots. Evaluation necessitates a neurologic examination and
imaging using an MRI/CT scan. A degenerating disc loses some
thickness and is less flexible, causing inter-vertebrae space to narrow.
A radiologist diagnoses an Intervertebral Disc Degeneration (IDD) by
localizing every inter-vertebral disc and identifying the pathology in
a disc based on its geometry and appearance. Accurate localizing is
necessary to diagnose IDD pathology. But, the underlying image
signal is ambiguous: a disc’s intensity overlaps the spinal nerve
fibres. Even the structure changes from case to case, with possible
spinal column bending (scoliosis). The inter-vertebral disc
pathology’s quantitative assessment needs accurate localization of the
cervical region discs. In this work, the efficacy of multilevel set
segmentation model, to segment cervical discs is investigated. The
segmented images are annotated using a simple distance matrix.
Abstract: Paranoid ideation is a common thought process that
constitutes a defense against perceived social threats. The current
study aimed at the characterization of paranoid ideation in youths and
to explore the possible predictors involved in the development of
paranoid ideations. Paranoid ideation, shame, submission, early
childhood memories and current depressive, anxious and stress
symptomatology were assessed in a sample of 1516 Portuguese
youths. Higher frequencies of paranoid ideation were observed,
particularly in females and youths from lower socioeconomic status.
The main predictors identified relates to submissive behaviors and
adverse childhood experiences, and especially to shame feelings. The
current study emphasizes that the these predictors are similar to
findings in adults and clinical populations, and future implications to
research and clinical practice aiming at paranoid ideations are
discussed, as well as the pertinence of the study of mediating factors
that allow a wider understanding of this thought process in younger
populations and the prevention of psychopathology in adulthood.
Abstract: Cortisol is essential to the regulation of the immune
system and yawning is a pathological symptom of multiple sclerosis
(MS). Electromyography activity (EMG) in the jaw muscles typically
rises when the muscles are moved and with yawning is highly
correlated with cortisol levels in healthy people. Saliva samples from
59 participants were collected at the start and after yawning, or at the
end of the presentation of yawning-provoking stimuli, in the absence
of a yawn, together with EMG data and questionnaire data: Hospital
Anxiety and Depression Scale, Yawning Susceptibility Scale,
General Health Questionnaire, demographic, health details. Exclusion
criteria: chronic fatigue, diabetes, fibromyalgia, heart condition, high
blood pressure, hormone replacement therapy, multiple sclerosis,
stroke. Significant differences were found between the saliva cortisol
samples for the yawners, t (23) = -4.263, p = 0.000, as compared with
the non-yawners between rest and post-stimuli, which was nonsignificant.
Significant evidence was found to support the Thompson
Cortisol Hypothesis suggesting that rises in cortisol levels are
associated with yawning. Further research is exploring the use of
cortisol as an early diagnostic tool for MS. Ethics approval granted
and professional code of conduct, confidentiality, and safety issues
are approved therein.