Abstract: The host response in peri-implant tissue may differ from that in periodontal tissue in a healthy individual. The purpose of this study is to investigate the expression of inflammatory cytokines in peri-implant crevicular fluid (PICF) from single implant with different abutment types in comparison to healthy periodontal tissue. 19 participants with healthy implants and teeth were recruited according to inclusion and exclusion criteria. PICF and gingival crevicular fluid (GCF) was collected using sterile paper points. The expression level of inflammatory cytokines including IL-1α, IL-1β, TNF-α, IFN-γ, IL-6, and IL-8 was assessed using enzyme-linked immunosorbent assay (ELISA). Paired t test was used to compare the expression levels of inflammatory cytokines around natural teeth and peri-implant in PICF and GCF of the same individual. The Independent t-test was used to compare the expression levels of inflammatory cytokines in PICF from titanium and UCLA abutment. Expression of IL-6, TNF-α, and IFN-γ in PICF was not statistically different from GCF among titanium and UCLA abutment group. However, the level of IL-1α in the PICF from the implants with UCLA abutment was significantly higher than GCF (P=0.030). In addition, the level of IL-1β in PICF from the implants with titanium abutment was significantly higher than GCF (P=0.032). When different abutment types was compared, IL-8 expression in PICF from implants with UCLA abutment was significantly higher than titanium abutment (P=0.003).
Abstract: COMTES FHT has been active in a field of research and development of high-strength wires for quite some time. The main material was pure titanium. The primary goal of this effort is to develop a continuous production process for ultrafine and nanostructured materials with the aid of severe plastic deformation (SPD). This article outlines mechanical and microstructural properties of the materials and the options available for testing the components made of these materials. Ti Grade 2 and Grade 4 wires are the key products of interest. Ti Grade 2 with ultrafine to nano-sized grain shows ultimate strength of up to 1050 MPa. Ti Grade 4 reaches ultimate strengths of up to 1250 MPa. These values are twice or three times as higher as those found in the unprocessed material. For those fields of medicine where implantable metallic materials are used, bulk ultrafine to nanostructured titanium is available. It is manufactured by SPD techniques. These processes leave the chemical properties of the initial material unchanged but markedly improve its final mechanical properties, in particular, the strength. Ultrafine to nanostructured titanium retains all the significant and, from the biological viewpoint, desirable properties that are important for its use in medicine, i.e. those properties which made pure titanium the preferred material also for dental implants.
Abstract: There are many types of mechanical failure on the
dental implant. In this project, the failure that needs to take into
consideration is the bone resorption on the dental implant. Human
bone has its ability to remodel after the implantation. As the dental
implant is installed into the bone, the bone will detect and change the
bone structure to achieve new biomechanical environment. This
phenomenon is known as bone remodeling. The objective of the
project is to improve the performance of dental implant by using
different types of design. These designs are used to analyze and
predict the failure of the dental implant by using finite element
analysis (FEA) namely ANSYS. The bone is assumed to be fully
attached to the implant or cement. Hence, results are then compared
with other researchers. The results were presented in the form of Von
Mises stress, normal stress, shear stress analysis, and displacement.
The selected design will be analyzed further based on a theoretical
calculation of bone remodeling on the dental implant. The results
have shown that the design constructed passed the failure analysis.
Therefore, the selected design is proven to have a stable performance
at the recovery stage.
Abstract: Titanium and its alloys have been used extensively over the past 25 years as biomedical materials in orthopedic and dental applications because of their good mechanical properties, corrosion resistance, and biocompatibility. It is known that the surface properties of titanium implants can enhance the cellular response and play an important role in Osseo integration. The rate and quality of Osseo integration in titanium implants are related to their surface properties. The purpose of this investigation was to evaluate the effect of sandblasting and acid etching on surface morphology, roughness, the wettability of titanium. The surface properties will be characterized by scanning electron microscopy and contact angle and roughness measurements. The results show that surface morphology, roughness, and wettability were changed and enhanced by these treatments.
Abstract: The aim of this retrospective study was to evaluate the
parameters of dental implants such as patient gender, number of
implant, failed implant before prosthetic restorations and failed
implant after implantation and failed implant after prosthetic
restorations. 135 male and 99 female patients, total 234 implant
patients which have been treated with 450 implant between 2005-
2009 years in GATA Haydarpasa Training Hospital Dental Service.
Twelve implants were failed before prosthetic restorations. Four
implant were failed after fixed prosthetic restorations. Cumulative
survival rate after prostheses were 97.56 % during 6 years period.
Abstract: An implant elicits a biological response in the
surrounding tissue which determines the acceptance and long-term
function of the implant. Dental implants have become one of the
main therapy methods in clinic after teeth lose. A successful implant
is in contact with bone and soft tissue represent by fibroblasts. In our
study we focused on the interaction between six different chemically
and physically modified titanium implants (Tis-MALP, Tis-O, Tis-
OA, Tis-OPAAE, Tis-OZ, Tis-OPAE) with alveolar fibroblasts as
well as with five type of microorganisms (S. epidermis, S.mutans, S.
gordonii, S. intermedius, C.albicans). The analysis of microorganism
adhesion was determined by CFU (colony forming unite) and biofilm
formation. The presence of α3β1 and vinculin expression on alveolar
fibroblasts was demonstrated using phospho specific cell based
ELISA (PACE). Alveolar fibroblasts have the highest expression of
these proteins on Tis-OPAAE and Tis-OPAE. It corresponds with
results from bacterial adhesion and biofilm formation and it was
related to the lowest production of collagen I by alveolar fibroblasts
on Tis-OPAAE titanium disc.
Abstract: In this study, stress distributions on dental implants
made of functionally graded biomaterials (FGBM) are investigated
numerically. The implant body is considered to be subjected to axial
compression loads. Numerical problem is assumed to be 2D, and
ANSYS commercial software is used for the analysis. The cross
section of the implant thread varies as varying the height (H) and the
width (t) of the thread. According to thread dimensions of implant
and material properties of FGBM, equivalent stress distribution on
the implant is determined and presented with contour plots along
with the maximum equivalent stress values. As a result, with
increasing material gradient parameter (n), the equivalent stress
decreases, but the minimum stress distribution increases. Maximum
stress values decrease with decreasing implant radius (r). Maximum
von Mises stresses increases with decreasing H when t is constant.
On the other hand, the stress values are not affected by variation of t
in the case of H = constant.