Abstract: This study aimed at developing an inverse heat transfer approach for predicting the time-varying freezing front and the temperature distribution of tumors during cryosurgery. Using a temperature probe pressed against the layer of tumor, the inverse approach is able to predict simultaneously the metabolic heat generation and the blood perfusion rate of the tumor. Once these parameters are predicted, the temperature-field and time-varying freezing fronts are determined with the direct model. The direct model rests on one-dimensional Pennes bioheat equation. The phase change problem is handled with the enthalpy method. The Levenberg-Marquardt Method (LMM) combined to the Broyden Method (BM) is used to solve the inverse model. The effect (a) of the thermal properties of the diseased tissues; (b) of the initial guesses for the unknown thermal properties; (c) of the data capture frequency; and (d) of the noise on the recorded temperatures is examined. It is shown that the proposed inverse approach remains accurate for all the cases investigated.
Abstract: To increase the temperature contrast in thermal
images, the characteristics of the electrical conductivity and thermal
imaging modalities can be combined. In this experimental study, it is
objected to observe whether the temperature contrast created by the
tumor tissue can be improved just due to the current application
within medical safety limits. Various thermal breast phantoms are
developed to simulate the female breast tissue. In vitro experiments
are implemented using a thermal infrared camera in a controlled
manner. Since experiments are implemented in vitro, there is no
metabolic heat generation and blood perfusion. Only the effects and
results of the electrical stimulation are investigated. Experimental
study is implemented with two-dimensional models. Temperature
contrasts due to the tumor tissues are obtained. Cancerous tissue is
determined using the difference and ratio of healthy and tumor
images. 1 cm diameter single tumor tissue causes almost 40 °mC
temperature contrast on the thermal-breast phantom. Electrode
artifacts are reduced by taking the difference and ratio of background
(healthy) and tumor images. Ratio of healthy and tumor images show
that temperature contrast is increased by the current application.
Abstract: An attempt has been made to develop a
seminumerical model to study temperature variations in dermal
layers of human limbs. The model has been developed for two
dimensional steady state case. The human limb has been assumed to
have elliptical cross section. The dermal region has been divided
into three natural layers namely epidermis, dermis and subdermal
tissues. The model incorporates the effect of important physiological
parameters like blood mass flow rate, metabolic heat generation, and
thermal conductivity of the tissues. The outer surface of the limb is
exposed to the environment and it is assumed that heat loss takes
place at the outer surface by conduction, convection, radiation, and
evaporation. The temperature of inner core of the limb also varies at
the lower atmospheric temperature. Appropriate boundary conditions
have been framed based on the physical conditions of the problem.
Cubic splines approach has been employed along radial direction and
Fourier series along angular direction to obtain the solution. The
numerical results have been computed for different values of
eccentricity resembling with the elliptic cross section of the human
limbs. The numerical results have been used to obtain the
temperature profile and to study the relationships among the various
physiological parameters.