Abstract: The primary tool currently used to pre-process 10X chromium single-cell ATAC-seq data is Cell Ranger, which can take very long to run on standard datasets. To facilitate rapid pre-processing that enables reproducible workflows, we present a suite of tools called scATAK for pre-processing single-cell ATAC-seq data that is 15 to 18 times faster than Cell Ranger on mouse and human samples. Our tool can also calculate chromatin interaction potential matrices and generate open chromatin signal and interaction traces for cell groups. We use scATAK tool to explore the chromatin regulatory landscape of a healthy adult human brain and unveil cell-type specific features, and show that it provides a convenient and computational efficient approach for pre-processing single-cell ATAC-seq data.
Abstract: In order to reduce the number of deaths due to heart
problems, we propose the use of Hierarchical Temporal Memory
Algorithm (HTM) which is a real time anomaly detection algorithm.
HTM is a cortical learning algorithm based on neocortex used for
anomaly detection. In other words, it is based on a conceptual theory
of how the human brain can work. It is powerful in predicting unusual
patterns, anomaly detection and classification. In this paper, HTM
have been implemented and tested on ECG datasets in order to detect
cardiac anomalies. Experiments showed good performance in terms
of specificity, sensitivity and execution time.
Abstract: Today, the mankind is in the stage of development, every day comes with new proposal of technology, in order to secure these types of technology, we also prepare high yielding security modules to conserve these resources. The capacity of human brain to recognize anything is far more than any species; this is all due to our developing cycle of curiosity. In this paper, we proposed a scheme based on graphical password using QR Code which provides more security to the recent online system. It also contains a supportive sound signature. In this system, authentication is done using sequence of images in QR code form. Users select one click-point per image with the help of QR scanner or recognizer. The encoded phrase in a QR code emphasizes the minimum probability of attacking via shoulder surfing or other attacks.
Abstract: This paper presents a paradigm for characterization and checking of human noise behavior. The definitions of ‘Noise’ and ‘Noise Behavior’ are devised. The concept of characterization and examining of Noise Behavior is obtained from the proposed paradigm of Psychoacoustics. The measurement of human noise behavior is discussed through definitions of noise sources and noise measurements. The noise sources, noise measurement equations and noise filters are further illustrated through examples. The theory and significance of solar energy acoustics is presented for life and its activities. Human comfort and health are correlated with human brain through physiological responses and noise protection. Examples of heat stress, intense heat, sweating and evaporation are also enumerated.
Abstract: A comprehensive study of object recognition in the human brain requires combining both spatial and temporal analysis of brain activity. Here, we are mainly interested in three issues: the time perception of visual objects, the ability of discrimination between two particular categories (objects vs. animals), and the possibility to identify a particular spatial representation of visual objects. Our experiment consisted of acquiring dense electroencephalographic (EEG) signals during a picture-naming task comprising a set of objects and animals’ images. These EEG responses were recorded from nine participants. In order to determine the time perception of the presented visual stimulus, we analyzed the Event Related Potentials (ERPs) derived from the recorded EEG signals. The analysis of these signals showed that the brain perceives animals and objects with different time instants. Concerning the discrimination of the two categories, the support vector machine (SVM) was applied on the instantaneous EEG (excellent temporal resolution: on the order of millisecond) to categorize the visual stimuli into two different classes. The spatial differences between the evoked responses of the two categories were also investigated. The results showed a variation of the neural activity with the properties of the visual input. Results showed also the existence of a spatial pattern of electrodes over particular regions of the scalp in correspondence to their responses to the visual inputs.
Abstract: Neural activity in the human brain starts from the
early stages of prenatal development. This activity or signals
generated by the brain are electrical in nature and represent not only
the brain function but also the status of the whole body. At the
present moment, three methods can record functional and
physiological changes within the brain with high temporal resolution
of neuronal interactions at the network level: the
electroencephalogram (EEG), the magnet oencephalogram (MEG),
and functional magnetic resonance imaging (fMRI); each of these has
advantages and shortcomings. EEG recording with a large number of
electrodes is now feasible in clinical practice. Multichannel EEG
recorded from the scalp surface provides very valuable but indirect
information about the source distribution. However, deep electrode
measurements yield more reliable information about the source
locations intracranial recordings and scalp EEG are used with the
source imaging techniques to determine the locations and strengths of
the epileptic activity. As a source localization method, Low
Resolution Electro-Magnetic Tomography (LORETA) is solved for
the realistic geometry based on both forward methods, the Boundary
Element Method (BEM) and the Finite Difference Method (FDM). In
this paper, we review the findings EEG- LORETA about epilepsy.
Abstract: The study of the electrical signals produced by neural
activities of human brain is called Electroencephalography. In this
paper, we propose an automatic and efficient EEG signal
classification approach. The proposed approach is used to classify the
EEG signal into two classes: epileptic seizure or not. In the proposed
approach, we start with extracting the features by applying Discrete
Wavelet Transform (DWT) in order to decompose the EEG signals
into sub-bands. These features, extracted from details and
approximation coefficients of DWT sub-bands, are used as input to
Principal Component Analysis (PCA). The classification is based on
reducing the feature dimension using PCA and deriving the supportvectors
using Support Vector Machine (SVM). The experimental are
performed on real and standard dataset. A very high level of
classification accuracy is obtained in the result of classification.
Abstract: With a long history, dual-task has become one of the
most intriguing research fields regarding human brain functioning
and cognition. However, findings considering effects of taskinterrelations
are limited (especially, in combined motor and
cognitive tasks). Therefore, we aimed at developing a measurement
system in order to analyse interrelation effects of cognitive and motor
tasks. On the one hand, the present study demonstrates the
applicability of the measurement system and on the other hand first
results regarding a systematisation of different task combinations are
shown. Future investigations should combine imagine technologies
and this developed measurement system.
Abstract: In this paper, an analytical study is made for the dynamic behavior of human brain tissue under transient loading. In this analytical model the Mooney-Rivlin constitutive law is coupled with visco-elastic constitutive equations to take into account both the nonlinear and time-dependent mechanical behavior of brain tissue. Five ordinary differential equations representing the relationships of five main parameters (radial stress, circumferential stress, radial strain, circumferential strain, and particle velocity) are obtained by using the characteristic method to transform five partial differential equations (two continuity equations, one motion equation, and two constitutive equations). Analytical expressions of the attenuation properties for spherical wave in brain tissue are analytically derived. Numerical results are obtained based on the five ordinary differential equations. The mechanical responses (particle velocity and stress) of brain are compared at different radii including 5, 6, 10, 15 and 25 mm under four different input conditions. The results illustrate that loading curves types of the particle velocity significantly influences the stress in brain tissue. The understanding of the influence by the input loading cures can be used to reduce the potentially injury to brain under head impact by designing protective structures to control the loading curves types.
Abstract: In this paper subjective film sound will be addressed as it gets represented in narrative cinema. First, “meta-diegetic” sound will be briefly explained followed by transition to “oneiric” sound. The representation of oneiric sound refers to a situation where film characters are experiencing some sort of an altered state of consciousness. Looking at an antlered state of consciousness in terms of human brain processes will point out to the cinematic ways of expression, which “mimic” those processes. Using several examples for different films will illustrate these points.
Abstract: Functional near infrared spectroscopy (fNIRS) is a
practical non-invasive optical technique to detect characteristic of
hemoglobin density dynamics response during functional activation of
the cerebral cortex. In this paper, fNIRS measurements were made in
the area of motor cortex from C4 position according to international
10-20 system. Three subjects, aged 23 - 30 years, were participated in
the experiment.
The aim of this paper was to evaluate the effects of different motor
activation tasks of the hemoglobin density dynamics of fNIRS signal.
The chaotic concept based on deterministic dynamics is an important
feature in biological signal analysis. This paper employs the chaotic
properties which is a novel method of nonlinear analysis, to analyze
and to quantify the chaotic property in the time series of the
hemoglobin dynamics of the various motor imagery tasks of fNIRS
signal. Usually, hemoglobin density in the human brain cortex is
found to change slowly in time. An inevitable noise caused by various
factors is to be included in a signal. So, principle component analysis
method (PCA) is utilized to remove high frequency component. The
phase pace is reconstructed and evaluated the Lyapunov spectrum, and
Lyapunov dimensions. From the experimental results, it can be
conclude that the signals measured by fNIRS are chaotic.
Abstract: Today, building automation is advancing from simple
monitoring and control tasks of lightning and heating towards more
and more complex applications that require a dynamic perception
and interpretation of different scenes occurring in a building. Current
approaches cannot handle these newly upcoming demands. In this
article, a bionically inspired approach for multimodal, dynamic scene
perception and interpretation is presented, which is based on neuroscientific
and neuro-psychological research findings about the perceptual
system of the human brain. This approach bases on data from diverse
sensory modalities being processed in a so-called neuro-symbolic
network. With its parallel structure and with its basic elements being
information processing and storing units at the same time, a very
efficient method for scene perception is provided overcoming the
problems and bottlenecks of classical dynamic scene interpretation
systems.
Abstract: Visual inputs are one of the key sources from which
humans perceive the environment and 'understand' what is
happening. Artificial systems perceive the visual inputs as digital
images. The images need to be processed and analysed. Within the
human brain, processing of visual inputs and subsequent
development of perception is one of its major functionalities. In this
paper we present part of our research project, which aims at the
development of an artificial model for visual perception (or
'understanding') based on the human perceptive and cognitive
systems. We propose a new model for perception from visual inputs
and a way of understaning or interpreting images using the model.
We demonstrate the implementation and use of the model with a real
image data set.
Abstract: The way music is interpreted by the human brain is a very interesting topic, but also an intricate one. Although this domain has been studied for over a century, many gray areas remain in the understanding of music. Recent advances have enabled us to perform accurate measurements of the time taken by the human brain to interpret and assimilate a sound. Cognitive computing provides tools and development environments that facilitate human cognition simulation. ACT-R is a cognitive architecture which offers an environment for implementing human cognitive tasks. This project combines our understanding of the music interpretation by a human listener and the ACT-R cognitive architecture to build SINGER, a computerized simulation for listening and recalling songs. The results are similar to human experimental data. Simulation results also show how it is easier to remember short melodies than long melodies which require more trials to be recalled correctly.
Abstract: Biologically human brain processes information in both unimodal and multimodal approaches. In fact, information is progressively abstracted and seamlessly fused. Subsequently, the fusion of multimodal inputs allows a holistic understanding of a problem. The proliferation of technology has exponentially produced various sources of data, which could be likened to being the state of multimodality in human brain. Therefore, this is an inspiration to develop a methodology for exploring multimodal data and further identifying multi-view patterns. Specifically, we propose a brain inspired conceptual model that allows exploration and identification of patterns at different levels of granularity, different types of hierarchies and different types of modalities. A structurally adaptive neural network is deployed to implement the proposed model. Furthermore, the acquisition of multi-view patterns with the proposed model is demonstrated and discussed with some experimental results.
Abstract: Functional Magnetic Resonance Imaging(fMRI) is a
noninvasive imaging technique that measures the hemodynamic
response related to neural activity in the human brain. Event-related
functional magnetic resonance imaging (efMRI) is a form of
functional Magnetic Resonance Imaging (fMRI) in which a series of
fMRI images are time-locked to a stimulus presentation and averaged
together over many trials. Again an event related potential (ERP) is a
measured brain response that is directly the result of a thought or
perception. Here the neuronal response of human visual cortex in
normal healthy patients have been studied. The patients were asked
to perform a visual three choice reaction task; from the relative
response of each patient corresponding neuronal activity in visual
cortex was imaged. The average number of neurons in the adult
human primary visual cortex, in each hemisphere has been estimated
at around 140 million. Statistical analysis of this experiment was
done with SPM5(Statistical Parametric Mapping version 5) software.
The result shows a robust design of imaging the neuronal activity of
human visual cortex.
Abstract: Human identification at a distance has recently gained
growing interest from computer vision researchers. Gait recognition
aims essentially to address this problem by identifying people based
on the way they walk [1]. Gait recognition has 3 steps. The first step
is preprocessing, the second step is feature extraction and the third
one is classification. This paper focuses on the classification step that
is essential to increase the CCR (Correct Classification Rate).
Multilayer Perceptron (MLP) is used in this work. Neural Networks
imitate the human brain to perform intelligent tasks [3].They can
represent complicated relationships between input and output and
acquire knowledge about these relationships directly from the data
[2]. In this paper we apply MLP NN for 11 views in our database and
compare the CCR values for these views. Experiments are performed
with the NLPR databases, and the effectiveness of the proposed
method for gait recognition is demonstrated.
Abstract: This paper investigates the control of a bouncing
ball using Model Predictive Control. Bouncing ball is a benchmark
problem for various rhythmic tasks such as juggling, walking,
hopping and running. Humans develop intentions which may be
perceived as our reference trajectory and tries to track it. The
human brain optimizes the control effort needed to track its
reference; this forms the central theme for control of bouncing ball
in our investigations.