Abstract: Autofluorescence Imaging (AFI) is a technology for detecting early carcinogenesis of the gastrointestinal tract in recent years. Compared with traditional white light endoscopy (WLE), this technology greatly improves the detection accuracy of early carcinogenesis, because the colors of normal tissues are different from cancerous tissues. Thus, edge detection can distinguish them in grayscale images. In this paper, based on the traditional Sobel edge detection method, optimization has been performed on this method which considers the environment of the gastrointestinal, including adaptive threshold and morphological processing. All of the processes are implemented on our self-designed system based on the image sensor OV6930 and Field Programmable Gate Array (FPGA), The system can capture the gastrointestinal image taken by the lens in real time and detect edges. The final experiments verified the feasibility of our system and the effectiveness and accuracy of the edge detection algorithm.
Abstract: Objective: Safety and efficacy of Ahmed glaucoma
valve implantation for the management of uveitis induced glaucoma
evaluated on the five dogs with uncontrollable glaucoma. Materials
and Methods: Ahmed Glaucoma Valve (AGV®; New World
Medical, Rancho Cucamonga, CA, USA) is a flow restrictive, nonobstructive
self-regulating valve system. Preoperative ocular
evaluation included direct ophthalmoscopy and measurement of the
intraocular pressure (IOP). The implant was examined and primed
prior to implantation. The selected site of the valve implantation was
the superior quadrant between the superior and lateral rectus muscles.
A fornix-based incision was made through the conjunectiva and
Tenon’s capsule. A pocket is formed by blunt dissection of Tenon’s
capsule from the episclera. The body of the implant was inserted into
the pocket with the leading edge of the device around 8-10 mm from
the limbus. Results: No post-operative complications were detected
in the operated eyes except a persistent corneal edema occupied the
upper half of the cornea in one case. Hyphaema was very mild and
seen only in two cases which resolved quickly two days after surgery.
Endoscopical evaluation for the operated eyes revealed a normal
ocular fundus with clearly visible optic papilla, tapetum and retinal
blood vessels. No evidence of hemorrhage, infection, adhesions or
retinal abnormalities was detected. Conclusion: Ahmed glaucoma
valve is safe and effective implant for treatment of uveitic glaucoma
in dogs.
Abstract: Upper gastrointestinal endoscopy is a commonly performed diagnostic and therapeutic procedure and has many adverse effects like cardiopulmonary complications, complications related to sedation, infectious complications, bleeding and perforation. So this study was undertaken to evaluate important variables like patient’s age, gender and stage of the procedure in relation to the cardiopulmonary changes during diagnostic upper gastrointestinal endoscopy by monitoring oxygen saturation, blood pressure, heart rate and electrocardiogram. This is a prospective longitudinal hospital based study involving a total of 140 consecutive patients, at Sri. B. M. Patil Medical College, Hospital and Research Centre. Cardiopulmonary changes during upper gastrointestinal endoscopy are more common in the age groups of 51-60 years, with equal frequency in both male and female. Oxygen saturation levels decreased by about 4% in both sexes during introduction of endoscopy. Mild to moderate hypoxia was found in 32% of the study group. Severe hypoxia was found in 5% of the patients, mostly in those patients who are above 50 years of age. Tachycardia was noted in 88% of the study group patients. Blood pressure increased to hypertension levels in 22 patients (15.7%) which returned to normal within few minutes after the procedure. S-T depression was noticed in 4% of patients and T wave inversion in 8% of patients during upper gastrointestinal endoscopy. All these changes disappeared after 10 minutes after the endoscopy. Cardiopulmonary changes are common during upper gastrointestinal endoscopy. Maximum changes in oxygen saturation, heart rate and blood pressure occurred immediately after the introduction of endoscope. The cardiopulmonary changes did not manifest into any identifiable clinical symptoms. The rate of recovery was faster in younger age groups and women.
Abstract: In this research study, an intelligent detection system
to support medical diagnosis and detection of abnormal lesions by
processing endoscopic images is presented. The images used in this
study have been obtained using the M2A Swallowable Imaging
Capsule - a patented, video color-imaging disposable capsule.
Schemes have been developed to extract texture features from the
fuzzy texture spectra in the chromatic and achromatic domains for a
selected region of interest from each color component histogram of
endoscopic images. The implementation of an advanced fuzzy
inference neural network which combines fuzzy systems and
artificial neural networks and the concept of fusion of multiple
classifiers dedicated to specific feature parameters have been also
adopted in this paper. The achieved high detection accuracy of the
proposed system has provided thus an indication that such intelligent
schemes could be used as a supplementary diagnostic tool in
endoscopy.
Abstract: Wireless capsule endoscopy provides real-time images in the digestive tract. Capsule images are usually low resolution and are diverse images due to travel through various regions of human body. Color information has been a primary reference in predicting abnormalities such as bleeding. Often color is not sufficient for this purpose. In this study, we took morphological shapes into account as additional, but important criterion. First, we processed gastric images in order to indentify various objects in the image. Then, we analyzed color information in the object. In this way, we could remove unnecessary information and increase the accuracy. Compared to our previous investigations, we could handle images of various degrees of brightness and improve our diagnostic algorithm.
Abstract: Automatic determination of blood in less bright or
noisy capsule endoscopic images is difficult due to low S/N ratio.
Especially it may not be accurate to analyze these images due to the
influence of external disturbance. Therefore, we proposed detection
methods that are not dependent only on color bands. In locating
bleeding regions, the identification of object outlines in the frame and
features of their local colors were taken into consideration. The results
showed that the capability of detecting bleeding was much improved.
Abstract: Wireless capsule Endoscopy (WCE) has rapidly
shown its wide applications in medical domain last ten years
thanks to its noninvasiveness for patients and support for thorough
inspection through a patient-s entire digestive system including
small intestine. However, one of the main barriers to efficient
clinical inspection procedure is that it requires large amount of
effort for clinicians to inspect huge data collected during the
examination, i.e., over 55,000 frames in video. In this paper, we
propose a method to compute meaningful motion changes of
WCE by analyzing the obtained video frames based on regional
optical flow estimations. The computed motion vectors are used to
remove duplicate video frames caused by WCE-s imaging nature,
such as repetitive forward-backward motions from peristaltic
movements. The motion vectors are derived by calculating
directional component vectors in four local regions. Our
experiments are performed on small intestine area, which is of
main interest to clinical experts when using WCEs, and our
experimental results show significant frame reductions comparing
with a simple frame-to-frame similarity-based image reduction
method.
Abstract: Bleeding in the digestive duct is an important diagnostic parameter for patients. Blood in the endoscopic image can be determined by investigating the color tone of blood due to the degree of oxygenation, under- or over- illumination, food debris and secretions, etc. However, we found that how to pre-process raw images obtained from the capsule detectors was very important. We applied various image process methods suitable for the capsule endoscopic image in order to remove noises and unbalanced sensitivities for the image pixels. The results showed that much improvement was achieved by additional pre-processing techniques on the algorithm of determining bleeding areas.
Abstract: Image processing for capsule endoscopy requires large
memory and it takes hours for diagnosis since operation time is
normally more than 8 hours. A real-time analysis algorithm of capsule
images can be clinically very useful. It can differentiate abnormal
tissue from health structure and provide with correlation information
among the images. Bleeding is our interest in this regard and we
propose a method of detecting frames with potential bleeding in
real-time. Our detection algorithm is based on statistical analysis and
the shapes of bleeding spots. We tested our algorithm with 30 cases of
capsule endoscopy in the digestive track. Results were excellent where
a sensitivity of 99% and a specificity of 97% were achieved in
detecting the image frames with bleeding spots.
Abstract: Automatic detection of bleeding is of practical
importance since capsule endoscopy produces an extremely large
number of images. Algorithm development of bleeding detection in
the digestive tract is difficult due to different contrasts among the
images, food dregs, secretion and others. In this study, were assigned
weighting factors derived from the independent features of the
contrast and brightness between bleeding and normality. Spectral
analysis based on weighting factors was fast and accurate. Results
were a sensitivity of 87% and a specificity of 90% when the accuracy
was determined for each pixel out of 42 endoscope images.