Abstract: Most, if not all, public hospitals in Thailand have encountered a common problem regarding the increasing demand for medical services. The increasing number of patients causes so much strain on the hospital-s services, over-crowded, overloaded working hours, staff fatigue, medical error and long waiting time. This research studied the characteristics of operational processes of the medical care services at the medicine department in a large public university hospital. The research focuses on details regarding methods, procedures, processes, resources, and time management in overall processes. The simulation model is used as a tool to analyze the impact of various improvement strategies.
Abstract: In April 2009, a new variant of Influenza A virus
subtype H1N1 emerged in Mexico and spread all over the world. The
influenza has three subtypes in human (H1N1, H1N2 and H3N2)
Types B and C influenza tend to be associated with local or regional
epidemics. Preliminary genetic characterization of the influenza
viruses has identified them as swine influenza A (H1N1) viruses.
Nucleotide sequence analysis of the Haemagglutinin (HA) and
Neuraminidase (NA) are similar to each other and the majority of
their genes of swine influenza viruses, two genes coding for the
neuraminidase (NA) and matrix (M) proteins are similar to
corresponding genes of swine influenza. Sequence similarity between
the 2009 A (H1N1) virus and its nearest relatives indicates that its
gene segments have been circulating undetected for an extended
period. Nucleic acid sequence Maximum Likelihood (MCL) and
DNA Empirical base frequencies, Phylogenetic relationship amongst
the HA genes of H1N1 virus isolated in Genbank having high
nucleotide sequence homology.
In this paper we used 16 HA nucleotide sequences from NCBI for
computing sequence relationships similarity of swine influenza A
virus using the following method MCL the result is 28%, 36.64% for
Optimal tree with the sum of branch length, 35.62% for Interior
branch phylogeny Neighber – Join Tree, 1.85% for the overall
transition/transversion, and 8.28% for Overall mean distance.
Abstract: SEMG (Surface Electromyogram) is one of the
bio-signals and is generated from the muscle. And there are many
research results that use forearm EMG to detect hand motions. In this
paper, we will talk about our developed the robot hand system that can
control grasping power by SEMG. In our system, we suppose that
muscle power is proportional to the amplitude of SEMG. The power is
estimated and the grip power of a robot hand is able to be controlled
using estimated muscle power in our system. In addition, to perform a
more precise control can be considered to build a closed loop feedback
system as an object to a subject to pressure from the edge of hand. Our
objectives of this study are the development of a method that makes
perfect detection of the hand grip force possible using SEMG patterns,
and applying this method to the man-machine interface.
Abstract: The use of machine vision to inspect the outcome of
surgical tasks is investigated, with the aim of incorporating this
approach in robotic surgery systems. Machine vision is a non-contact
form of inspection i.e. no part of the vision system is in direct contact
with the patient, and is therefore well suited for surgery where
sterility is an important consideration,. As a proof-of-concept, three
primary surgical tasks for a common neurosurgical procedure were
inspected using machine vision. Experiments were performed on
cadaveric pig heads to simulate the two possible outcomes i.e.
satisfactory or unsatisfactory, for tasks involved in making a burr
hole, namely incision, retraction, and drilling. We identify low level
image features to distinguish the two outcomes, as well as report on
results that validate our proposed approach. The potential of using
machine vision in a surgical environment, and the challenges that
must be addressed, are identified and discussed.
Abstract: The analysis to detect arrhythmias and life-threatening
conditions are highly essential in today world and this analysis
can be accomplished by advanced non-linear processing methods
for accurate analysis of the complex signals of heartbeat dynamics.
In this perspective, recent developments in the field of multiscale
information content have lead to the Microcanonical Multiscale
Formalism (MMF). We show that such framework provides several
signal analysis techniques that are especially adapted to the
study of heartbeat dynamics. In this paper, we just show first hand
results of whether the considered heartbeat dynamics signals have
the multiscale properties by computing local preticability exponents
(LPEs) and the Unpredictable Points Manifold (UPM), and thereby
computing the singularity spectrum.
Abstract: The objective of current issue was to develop a model
of testicular herpes simplex virus (HSV) type I infection for
assessment of viral effect on fertility. 56 male mice were inoculated
intraperitoneally with different concentrations of HSV on 8 day post
partum. It was revealed that the optimal dose was 100 plaque
forming units per mice as it provided testicular infection in 100% of
survivors. HSV proteins were detected both in somatic and germ
cells (spermatogonia, spermatocytes, spermatides). Although DNA
load in testis was descending from 3 to 28 days post infection only
12.5% of infected males had offspring after mating with uninfected
females comparing to 87.5% in control (p=0.012). These results are
the first direct evidence for HSV impact in male sterility. Prepuberal
mice appeared to be a suitable model for investigation of
pathogenesis of virus-associated fertility disorders.
Abstract: It is necessary to incorporate technological advances
achieved in the field of engineering into dentistry in order to enhance
the process of diagnosis, treatment planning and enable the doctors to
render better treatment to their patients. To achieve this ultimate goal
long distance collaborations are often necessary. This paper discusses
the various collaborative tools and their applications to solve a few
burning problems confronted by the dentists. Customization is often
the solution to most of the problems. But rapid designing,
development and cost effective manufacturing is a difficult task to
achieve. This problem can be solved using the technique of digital
manufacturing. Cases from 6 major branches of dentistry have been
discussed and possible solutions with the help of state of art
technology using rapid digital manufacturing have been proposed in
the present paper. The paper also entails the usage of existing tools in
collaborative and digital manufacturing area.
Abstract: Diabetes is one of the high prevalence diseases
worldwide with increased number of complications, with retinopathy
as one of the most common one. This paper describes how data
mining and case-based reasoning were integrated to predict
retinopathy prevalence among diabetes patients in Malaysia. The
knowledge base required was built after literature reviews and
interviews with medical experts. A total of 140 diabetes patients- data
were used to train the prediction system. A voting mechanism selects
the best prediction results from the two techniques used. It has been
successfully proven that both data mining and case-based reasoning
can be used for retinopathy prediction with an improved accuracy of
85%.
Abstract: Bacillus subtilis strain LB5 produced lipopeptide
antibiotic iturin A-2 in liquid medium. Crude extract
from cell-free supernatant of B. subtilis cultivated broth extracted
with n-butanol showed antifungal activity to conidial germination of
Colletotrichum gloeosporioides. The germination of conidia was
completely inhibited by crude extract. The ultrastructure of conidia
after treated with crude extract was found an accumulation of vesiclelike
material between cell wall and plasma membrane while this
accumulation was not observed in untreated and germinated conidia.
Besides, the cell wall was not affected by crude extract.
Abstract: Many recent electrophysiological studies have
revealed the importance of investigating meditation state in order to
achieve an increased understanding of autonomous control of
cardiovascular functions. In this paper, we characterize heart rate
variability (HRV) time series acquired during meditation using
nonlinear dynamical parameters. We have computed minimum
embedding dimension (MED), correlation dimension (CD), largest
Lyapunov exponent (LLE), and nonlinearity scores (NLS) from HRV
time series of eight Chi and four Kundalini meditation practitioners.
The pre-meditation state has been used as a baseline (control) state to
compare the estimated parameters. The chaotic nature of HRV during
both pre-meditation and meditation is confirmed by MED. The
meditation state showed a significant decrease in the value of CD and
increase in the value of LLE of HRV, in comparison with premeditation
state, indicating a less complex and less predictable nature
of HRV. In addition, it was shown that the HRV of meditation state
is having highest NLS than pre-meditation state. The study indicated
highly nonlinear dynamic nature of cardiac states as revealed by
HRV during meditation state, rather considering it as a quiescent
state.
Abstract: The functional response of an infective is the relationship
between an infected individual-s infection rate and the abundance
of the number of susceptibles that one can potentially be infected.
In this paper, we consider defensive attitudes for HIV prevention
(primary prevention) while at the same time emphasizing on offensive
attitudes that reduce infection for those infected (secondary prevention).
We look at how defenses can protect an uninfected individual
in the case where high risk groups such as commercial sex workers
and those who deliberately go out to look for partners. We propose
an infection cycle that begins with a search, then an encounter,
a proposal and contact. The infection cycle illustrates the various
steps an infected individual goes through to successfully infect a
susceptible. For heterogeneous transmission of HIV, there will be no
infection unless there is contact. The ability to avoid an encounter,
detection, proposal and contact constitute defense.
Abstract: Imaging is defined as the process of obtaining
geometric images either two dimensional or three dimensional by scanning or digitizing the existing objects or products. In this research, it applied to retrieve 3D information of the human skin
surface in medical application. This research focuses on analyzing
and determining volume of leg ulcers using imaging devices. Volume
determination is one of the important criteria in clinical assessment of leg ulcer. The volume and size of the leg ulcer wound will give the
indication on responding to treatment whether healing or worsening.
Different imaging techniques are expected to give different result (and accuracies) in generating data and images. Midpoint projection
algorithm was used to reconstruct the cavity to solid model and compute the volume. Misinterpretation of the results can affect the
treatment efficacy. The objectives of this paper is to compare the
accuracy between two 3D data acquisition method, which is laser
triangulation and structured light methods, It was shown that using models with known volume, that structured-light-based 3D technique
produces better accuracy compared with laser triangulation data
acquisition method for leg ulcer volume determination.
Abstract: The cardiovascular system has become the most
important subject of clinical research, particularly measurement of
arterial blood flow. Therefore correct determination of arterial
diameter is crucial. We propose a novel, semi-automatic method for
artery lumen detection. The method is based on Gaussian probability
function. Usability of our proposed method was assessed by
analyzing ultrasound B-mode CFA video sequences acquired from
eleven healthy volunteers. The correlation coefficient between the
manual and semi-automatic measurement of arterial diameter was
0.996. Our proposed method for detecting artery boundary is novel
and accurate enough for the measurement of artery diameter.
Abstract: Functional gastrointestinal disorders (FGID) affect millions of people spread all age regardless of race and sex. Emotional stress and obesity have been associated with increased reporting of gastrointestinal (GI) symptoms, but the relationship between FGID and risk factors (emotional stress or obesity) is unclear. Our aim was to assess the changes of the mechanical characteristics on the gastrointestinal tracts of the mentally fatigued obese and normal rat models. Finally, using the physical characteristics with micro-indentation test, we made a close investigation into the relation between FGID and risk factors quantitatively.
Abstract: Pepper spray use has gained momentum since 1992
and although the active ingredient is readily available, it is considered
a weapon with restricted use in many regions, including The
Bahamas. In light of controversy in the literature regarding the
severity of presenting respiration complaints among individuals postacute
exposure of pepper spray inhalation, this descriptive case series
study was conducted to assess the respiratory status of persons
evaluated during a mass casualty in The Bahamas. Parameters noted
were patients- demographics and respiration severity determined via
clinical examination findings, disposition and follow-up review of the
20 persons. Their most common complaint was difficulty breathing
post exposure. Two required admission and stayed for
Abstract: This paper discusses the effectiveness of the EEG signal
for human identification using four or less of channels of two different
types of EEG recordings. Studies have shown that the EEG signal
has biometric potential because signal varies from person to person
and impossible to replicate and steal. Data were collected from 10
male subjects while resting with eyes open and eyes closed in 5
separate sessions conducted over a course of two weeks. Features
were extracted using the wavelet packet decomposition and analyzed
to obtain the feature vectors. Subsequently, the neural networks
algorithm was used to classify the feature vectors. Results show that,
whether or not the subjects- eyes were open are insignificant for a 4–
channel biometrics system with a classification rate of 81%. However,
for a 2–channel system, the P4 channel should not be included if data
is acquired with the subjects- eyes open. It was observed that for 2–
channel system using only the C3 and C4 channels, a classification
rate of 71% was achieved.
Abstract: The lubricating properties of commercially available
mucins originating from different animal organs, namely bovine
submaxillary mucin (BSM) and porcine gastric mucin (PGM), have
been characterized at polymeric surfaces for biomedical applications.
Atomic force microscopy (AFM) and pin-on-disk tribometry have
been employed for tribological studies at nanoscale and macroscale
contacts, respectively. Polystyrene (PS) was employed to represent
‘rigid’ contacts, whereas poly(dimethylsiloxane) (PDMS) was
employed to represent ‘soft contacts’. To understand the lubricating
properties of mucins in correlation with the coverage on surfaces,
adsorption properties of mucins onto the polymeric substrates have
been characterized by means of optical waveguide light-mode
spectroscopy (OWLS). Both mucins showed facile adsorption onto
both polymeric substrates, but the lubricity was highly dependent
upon the pH change between 2 and 7.
Abstract: Numerous divergence measures (spectral distance, cepstral
distance, difference of the cepstral coefficients, Kullback-Leibler
divergence, distance given by the General Likelihood Ratio, distance
defined by the Recursive Bayesian Changepoint Detector and the
Mahalanobis measure) are compared in this study. The measures are
used for detection of abrupt spectral changes in synthetic AR signals
via the sliding window algorithm. Two experiments are performed;
the first is focused on detection of single boundary while the second
concentrates on detection of a couple of boundaries. Accuracy of
detection is judged for each method; the measures are compared
according to results of both experiments.
Abstract: The potential of antioxidant activities of the plant
extract Gynura procumbens, Achyranthes aspera and Polygenum
tomentosum were studied by using 1, 1-diphenyl-2-picrylhydrazyl
(DPPH) .Antioxidant activity was qualitatively and quantitatively
determined. In this analysis , Ascorbic acid (Vitamin C) was used as
the standard .The antioxidant activities were observed all three plant
extracts and the EC50 values of G procumbens A.aspera and
P.tomemtosum were 13.7 μg /ml,14.37 μg /ml and 14.35 μg /ml.
Among these plants, G.procumbens is more potent antioxidant
activity then others. Antitumor activities were found with A.aspera
(s2) extracts in the dose of 100ppm in carrot disks and G.procumbens
(s1) and P.tomentosum (s3) in the dose of 1000 ppm. Therefore, these
herbal plants are used in traditional medicines.
Abstract: Automatic tube current modulation (ATCM) systems are available for all CT manufacturers and are used for the majority of patients. Understanding how the systems work and their influence on patient dose and image quality is important for CT users, in order to gain the most effective use of the systems. In the present study, a new phantom was used for evaluating dose distribution and image quality under the ATCM operation for the Toshiba Aquilion 64 CT scanner using different ATCM options and a fixed mAs technique. A routine chest, abdomen and pelvis (CAP) protocol was selected for study and Gafchromic film was used to measure entrance surface dose (ESD), peripheral dose and central axis dose in the phantom. The results show the dose reductions achievable with various ATCM options, in relation with the target noise. The doses and image noise distribution were more uniform when the ATCM system was implemented compared with the fixed mAs technique. The lower limit set for the tube current will affect the modulations especially for the lower dose option. This limit prevented the tube current being reduced further and therefore the lower dose ATCM setting resembled a fixed mAs technique. Selection of a lower tube current limit is likely to reduce doses for smaller patients in scans of chest and neck regions.