Abstract: An unrecorded experiment of use of the smartphone
as a tool for practical classes of histology is presented in this paper.
Behavior and learning of students of science courses at the University
were analyzed and compared as well as the mode of teaching of this
discipline and the appreciation of the students, using either digital
photographs taken by phone or drawings for record microscopic
observations, analyze and interpret histological sections of human or
animal tissues.
Abstract: Aim of this research study is to investigate and
establish the characteristics of brain dominances (BD) and multiple
intelligences (MI). This experimentation has been conducted for the
sample size of 552 undergraduate computer-engineering students. In
addition, mathematical formulation has been established to exhibit
the relation between thinking and intelligence, and its correlation has
been analyzed. Correlation analysis has been statistically measured
using Pearson’s coefficient. Analysis of the results proves that there
is a strong relational existence between thinking and intelligence.
This research is carried to improve the didactic methods in
engineering learning and also to improve e-learning strategies.
Abstract: This article briefly reviews the role of Indian
Pharmacopoeia Commission (IPC) for publications of Indian
Pharmacopoeia (IP) and National formulary of India (NFI) to some of
these anticipated changes, informs constituents about how they can
remain updated about progress and upcoming modifications to
official texts, and invites participation in the standards-setting
process, which are helpful to the practitioners, researchers, educators
and policy makers in the field of health care profession.
Abstract: Although, lanthanum carbonate has not been approved
by the FDA for treatment of hyperphosphatemia, we prospectively
evaluated the efficacy of the combination of Calcium hydroxyapatite
(CHAp) and Lanthanum Carbonate (LaC) for the treatment of
hyperphosphatemia on mice. CHAp was prepared by co-precipitation
method using Ca(OH)2, H3PO4, NH4OH with calcination at 1200ºC.
Lanthanum carbonate was prepared by chemical method using
NaHCO3 and LaCl3 at low pH environment, below 4.0. The
structures were characterized by FTIR spectra and SEM -EDX
analysis. The study group included 16 subjects-mice divided into four
groups according to the administered substance: lanthanum carbonate
(group A), CHAp (group B), lanthanum carbonate + CHAp (group C)
and salt water (group D). The results indicate a phosphate decrease
when subjects (mice) were treated with CHAp and lanthanum
carbonate (0.5% CMC), in a single dose of 1500 mg/kg. Serum
phosphate concentration decreased [(from 4.5 ± 0.8 mg/dL) to
4.05 ± 0.2 mg/dL), P < 0.01] in group A and in group C (to 3.6
± 0.2 mg/dL) at 12 hours from the administration. The combination
of CHAp and lanthanum carbonate is a suitable regimen for
hyperphosphatemia treatment because it avoids both the
hypercalcemia of CaCO3 and the adverse effects of CHAp.
Abstract: The arm length, hand length, hand breadth and middle
finger length of 1540 right-handed industrial workers of Haryana
state was used to assess the relationship between the upper limb
dimensions and stature. Initially, the data were analyzed using basic
univariate analysis and independent t-tests; then simple and multiple
linear regression models were used to estimate stature using SPSS
(version 17). There was a positive correlation between upper limb
measurements (hand length, hand breadth, arm length and middle
finger length) and stature (p < 0.01), which was highest for hand
length. The accuracy of stature prediction ranged from ± 54.897 mm
to ± 58.307 mm. The use of multiple regression equations gave better
results than simple regression equations. This study provides new
forensic standards for stature estimation from the upper limb
measurements of male industrial workers of Haryana (India). The
results of this research indicate that stature can be determined using
hand dimensions with accuracy, when only upper limb is available
due to any reasons likewise explosions, train/plane crashes, mutilated
bodies, etc. The regression formula derived in this study will be
useful for anatomists, archaeologists, anthropologists, design
engineers and forensic scientists for fairly prediction of stature using
regression equations.
Abstract: Humans are social mammals, of the primate order.
Our biology, our behaviour and our pathologies are unique to us. In
our desire to understand, reduce solitary confinement one source of
information is the many reports of social isolation of other social
mammals, especially primates. A behavioural study was conducted in
the department of pharmacology at Indira Gandhi Medical College,
Shimla in Himachalpradesh province in India using white albino
mice. Different behavioural parameters were observed by using open
field, tail suspension, tests for aggressive behaviour and social
interactions and the effect of isolation was studied. The results were
evaluated and the standard statistics were applied. The said study was
done to establish facts that isolation itself impairs social behaviour
and can lead to alcohol dependence as well as related drug
dependence.
Abstract: The purpose of this study is to investigate the kinematic
characteristics and differences of the snatch barbell trajectory of 53 kg
class female weight lifters. We take the 2014 Taiwan College Cup
players as examples, and tend to make kinematic applications through
the proven weightlifting barbell track system. The competition videos
are taken by consumer camcorder with a tripod which set up at the side
of the lifter. The results will be discussed in three parts, the first part is
various lifting phase, the second part is the compare lifting between
success and unsuccessful, and the third part is to compare the
outstanding player with the general. Conclusion through the barbell
can be used to observe the trajectories of our players lifting the usual
process cannot be observed in the presence of malfunction or habits, so
that the coach can find the problem and guide the players more
accurately. Our system can be applied in practice and competition to
increase the resilience of the lifter on the field.
Abstract: With drug resistance becoming widespread in
Plasmodium falciparum infections, the development of the alternative
drugs is the desired strategy for prevention and cure of malaria. Three
drug targets were selected to screen promising drug molecules from
the GSK library of 13469 molecules. Using an in silico structure-based
drug designing approach, the differences in binding energies of
the substrate and inhibitor were exploited between target sites of
parasite and human to design a drug molecule against Plasmodium.
The docking studies have shown several promising molecules from
GSK library with more effective binding as compared to the already
known inhibitors for the drug targets. Though stronger interaction has
been shown by several molecules as compared to the reference, few
molecules have shown the potential as drug candidates though in
vitro studies are required to validate the results. In case of
thymidylate synthase-dihydrofolatereductase (TS-DHFR), three
compounds have shown promise for future studies as potential drugs.
Abstract: Although there had been a many studies that shows
the impact of air pollution on physical health, comparatively less was
known of human behavioral responses and annoyance impacts.
Annoyance caused by air pollution is a public health problem because
it can be an ambient stressor causing stress and disease and can affect
quality of life. The objective of this work is to evaluate the
annoyance caused by air pollution in two different industrialized
urban areas, Dunkirk (France) and Vitoria (Brazil). The populations
of these cities often report feeling annoyed by dust. Surveys were
conducted, and the collected data were analyzed using statistical
analyses. The results show that sociodemographic variables,
importance of air quality, perceived industrial risk, perceived air
pollution and occurrence of health problems play important roles in
the perceived annoyance. These results show the existence of a
common problem in geographically distant areas and allow
stakeholders to develop prevention strategies.
Abstract: Precise capture of plantar 3D surface of the foot at the
loading gait phases on rigid substrates was found to be valuable for
the assessment of the physiology, health and problems of the feet.
Photogrammetry, a precision 3D spatial data capture technique is
suitable for this type of dynamic application. In this research, the
technique is utilised to study the plantar deformation as a result of
having a strip of kinesiology tape on the plantar surface during the
loading phase of gait. For this pilot study, one healthy adult male
subject was recruited under the University’s human research ethics
guidelines for this preliminary study. The 3D plantar deformation
data with and without applying the tape were analysed. The results
and analyses are presented together with detailed findings.
Abstract: For the treatment of acute and chronic lung diseases it is preferred to deliver medicaments by inhalation. The drug is delivered directly to tracheobronchial tree. This way allows the given medicament to get directly into the place of action and it makes rapid onset of action and maximum efficiency. The transport of aerosol particles in the particular part of the lung is influenced by their size, anatomy of the lungs, breathing pattern and airway resistance. This article deals with calculation of airway resistance in the lung model of Horsfield. It solves the problem of determination of the pressure losses in bifurcation and thus defines the pressure drop at a given location in the bronchial tree. The obtained data will be used as boundary conditions for transport of aerosol particles in a central part of bronchial tree realized by Computational Fluid Dynamics (CFD) approach. The results obtained from CFD simulation will allow us to provide information on the required particle size and optimal inhalation technique for particle transport into particular part of the lung.
Abstract: The aim of this study is to evaluate the effects of the
laser and partial vibration stimulation on the mice tibia with
morphological characteristics. Twenty female C57BL/6 mice (12
weeks old) were used for the experiment. The study was carried out on
four groups of animals each consisting of five mice. Four groups of
mice were ovariectomized. Animals were scanned at 0 and 2 weeks
after ovariectomy by using micro computed tomography to estimate
morphological characteristics of tibial trabecular bone. Morphological
analysis showed that structural parameters of multi-stimuli group
appear significantly better phase in BV/TV, BS/BV, Tb.Th, Tb.N,
Tb.Sp, and Tb.pf than single stimulation groups. However, single
stimulation groups didn’t show significant effect on tibia with Sham
group. This study suggests that multi-stimuli may restrain the change
as the degenerate phase on osteoporosis in the mice tibia.
Abstract: Background: The effectiveness of mirror therapy
(MT) has been investigated in acute hemiplegia. The present study
examines whether MT, given during chronic stroke, was more
effective in promoting motor recovery of the lower extremity and
walking speed than standard rehabilitation alone. Methods: The study
enrolled 30 patients with chronic stroke. Fifteen patients each were
assigned to the treatment group and the control group. All patients
received a conventional rehabilitation program for a 4-week period.
In addition to this rehabilitation program, patients in the treatment
group received mirror therapy for 4 weeks, 5 days a week. Main
measures: Passive ankle joint dorsiflexion range of motion, gait
speed, Brunnstrom stages of motor recovery, plantar flexor muscle
tone by Modified Ashworth Scale. Results: No significant difference
was found in the outcome measures among groups before treatment.
When compared with standard rehabilitation, mirror therapy
improved Ankle ROM, Brunnstrom stages and waking speed
(p < 0.05). However, there were no significant differences between
two groups on MAS (P > 0.05).Conclusion: Mirror therapy combined
with a conventional stroke rehabilitation program enhances lowerextremity
motor recovery and walking speed in chronic stroke
patients.
Abstract: Early detection of breast cancer saves many thousands
of lives each year via application of mammography and genetic
screening and many more lives could be saved if nurses are involved
in breast care screening practices. So, the aim of the study was to
identify nurse's role in early detection of breast cancer through
mammography and genetic screening and its impact on patient's
outcome. In order to achieve this aim, 400 women above 40 years,
asymptomatic were recruited for mammography and genetic
screening. In addition, 50 nurses and 6 technologists were involved in
the study. A descriptive analytical design was used. Five tools were
utilized: sociodemographic, mammographic examination and risk
factors, women's before, during and after mammography, items
relaying to technologists, and items related to nurses were also
obtained. The study finding revealed that 3% of women detected for
malignancy and 7.25% for fibroadenoma. Statistically significant
differences were found between mammography results and age,
family history, genetic screening, exposure to smoke, and using
contraceptive pills. Nurses have insufficient knowledge about
screening tests. Based on these findings the present study
recommended involvement of nurses in breast care which is very
important to in force population about screening practices.
Abstract: The aim of this study is to develop an anterior lumbar
interbody fusion (ALIF) PEEK cage suitable for Korean people. In this
study, CT images were obtained from Korean male (173cm, 71kg) and
3D Korean lumbar models were reconstructed based on the CT images
to investigate anatomical characteristics. Major design parameters of
anterior lumbar interbody fusion (ALIF) PEEK Cage were selected
using the morphological measurement information of the Korean
Lumbar models. Through finite element analysis and mechanical tests,
the developed ALIFPEEK Cage prototype was compared with the
Fidji Cage (Zimmer. Inc, USA) and it was found that the ALIF
prototype showed similar and/or superior mechanical performance
compared to the FidJi Cage. Also, clinical validation for the ALIF
PEEK Cage prototype was carried out to check predictable troubles in
surgical operations. Finally, it is considered that the convenience and
stability of the prototype was clinically verified.
Abstract: A novel hybrid model of the lumbar spine, allowing
fast static and dynamic simulations of the disc pressure
and the spine mobility, is introduced in this work. Our
contribution is to combine rigid bodies, deformable finite
elements, articular constraints, and springs into a unique model
of the spine. Each vertebra is represented by a rigid body
controlling a surface mesh to model contacts on the facet
joints and the spinous process. The discs are modeled using
a heterogeneous tetrahedral finite element model. The facet
joints are represented as elastic joints with six degrees of
freedom, while the ligaments are modeled using non-linear
one-dimensional elastic elements. The challenge we tackle
is to make these different models efficiently interact while
respecting the principles of Anatomy and Mechanics.
The mobility, the intradiscal pressure, the facet joint force and
the instantaneous center of rotation of the lumbar spine are
validated against the experimental and theoretical results of
the literature on flexion, extension, lateral bending as well as
axial rotation.
Our hybrid model greatly simplifies the modeling task and
dramatically accelerates the simulation of pressure within the
discs, as well as the evaluation of the range of motion and the
instantaneous centers of rotation, without penalizing precision.
These results suggest that for some types of biomechanical
simulations, simplified models allow far easier modeling and
faster simulations compared to usual full-FEM approaches
without any loss of accuracy.
Abstract: VACTERL association is a rare disorder with various
congenital malformations. The aetiology remains unknown.
Combination of at least three congenital anomalies of the following
criteria is required for diagnosis: vertebral defects, anal atresia,
cardiac anomalies, tracheo-esophageal fistula, renal anomalies, and
limb defects. The first case was 1-day old male neonate with multiple
congenital anomalies was bore from 28 years old mother. The mother
had history of pregnancy with lymphocyte therapy. His anomalies
included: defects in thoracic and lumbar vertebral, anal atresia,
bilateral hydronephrosis, atrial septal defect, and lower limb
abnormality. Other anomalies were cryptorchidism and nasal canal
narrowing. The second case was born with 32 weeks gestational age
from mother with history of pregnancy with lymphocyte therapy. He
had thoracic vertebral defect, cardiac anomalies and renal defect.
diagnosis based on clinical finding is VACTERL association. Early
diagnosis is very important to investigation and treatment of other
coexistence anomalies. VACTERL association in mothers with
history of pregnancy with lymphocyte therapy has suggested possibly
of relationship between VACTERL association and this method of
pregnancy.
Abstract: Background: With the perceived pain and poor
function experienced following knee arthroplasty, patients usually
feel un-satisfied. Yet, a controversy still persists on the appropriate
operative technique that doesn’t affect proprioception much.
Purpose: This study compared the effects of Cruciate Retaining
(CR) and Posterior Stabilized (PS) total knee arthroplasty (TKA on
dynamic balance, pain and functional performance following
rehabilitation.
Methods: Thirty patients with CRTKA (group I), thirty with
PSTKA (group II) and fifteen indicated for arthroplasty but weren’t
operated on yet (group III) participated in the study. The mean age
was 54.53±3.44, 55.13±3.48 and 55.33±2.32 years and BMI
35.7±3.03, 35.7±1.99 and 35.73±1.03 kg/m2 for groups I, II and III
respectively. The Berg Balance Scale (BBS), WOMAC pain subscale
and Timed Up-and-Go (TUG) and Stair-Climbing (SC) tests were
used for assessment. Assessments were conducted four weeks preand
post-operatively, three, six and twelve months post-operatively
with the control group being assessed at the same time intervals. The
post-operative rehabilitation involved hospitalization (1st week),
home-based (2nd-4th weeks), and outpatient clinic (5th-12th weeks)
programs, follow-up to all groups for twelve months.
Results: The Mixed design MANOVA revealed that group I had
significantly lower pain scores and SC time compared with group II
three, six and twelve months post-operatively. Moreover, the BBS
scores increased significantly and the pain scores and TUG and SC
time decreased significantly six months post-operatively compared
with four weeks pre- and post-operatively and three months postoperatively
in groups I and II with the opposite being true four weeks
post-operatively. But no significant differences in BBS scores, pain
scores and TUG and SC time between six and twelve months postoperatively
in groups I and II.
Interpretation/Conclusion: CRTKA is preferable to PSTKA,
possibly due to the preserved human proprioceptors in the un-excised
PCL.
Abstract: Background and aim: It has not been well studied
whether fentanyl-thiopental (FT) is effective and safe for PSA in
orthopedic procedures in Emergency Department (ED). The aim of
this trial was to evaluate the effectiveness of intravenous FT versus
fentanyl-midazolam (FM) in patients who suffered from shoulder
dislocation or distal radial fracture-dislocation.
Methods: In this randomized double-blinded study, Seventy-six
eligible patients were entered the study and randomly received
intravenous FT or FM. The success rate, onset of action and recovery
time, pain score, physicians’ satisfaction and adverse events were
assessed and recorded by treating emergency physicians. The
statistical analysis was intention to treat.
Results: The success rate after administrating loading dose in FT
group was significantly higher than FM group (71.7% vs. 48.9%,
p=0.04); however, the ultimate unsuccessful rate after 3 doses of
drugs in the FT group was higher than the FM group (3 to 1) but it
did not reach to significant level (p=0.61). Despite near equal onset
of action time in two study group (P=0.464), the recovery period in
patients receiving FT was markedly shorter than FM group
(P
Abstract: In Brazil, neonatal mortality rate is considered
incompatible with the country development conditions, and has been
a Public Health concern. Reduction in infant mortality rates has also
been part of the Millennium Development Goals, a commitment
made by countries, members of the Organization of United Nations
(OUN), including Brazil. Fetal mortality rate is considered a highly
sensitive indicator of health care quality. Suitable actions, such as
good quality and access to health services may contribute positively
towards reduction in these fetal and neonatal rates. With appropriate
antenatal follow-up and health care during gestation and delivery,
some death causes could be reduced or even prevented by means of
early diagnosis and intervention, as well as changes in risk factors
and interventions. Objectives: To study the quality of maternal and
infant health care based on fetal and neonatal mortality, as well as the
possible actions to prevent those deaths in Botucatu (Brazil).
Methods: Classification of prevention according to the International
Classification of Diseases and the modified Wigglesworth´s
classification. In order to evaluate adequacy, indicators of quality of
antenatal and delivery care were established by the authors. Results:
Considering fetal deaths, 56.7% of them occurred before delivery,
which reveals possible shortcomings in antenatal care, and 38.2% of
them were a result of intra- labor changes, which could be prevented
or reduced by adequate obstetric management. These findings were
different from those in the group of early neonatal deaths which were
also studied. Adequacy of health services showed that antenatal and
childbirth care was appropriate for 24% and 33.3% of pregnant
women, respectively, which corroborates the results of prevention.
These results revealed that shortcomings in obstetric and antenatal
care could be the causes of deaths in the study. Early and late
neonatal deaths have similar characteristics: 76% could be prevented
or reduced mainly by adequate newborn care (52.9%) and adequate
health care for gestational women (11.7%). When adequacy of care
was evaluated, childbirth and newborn care was adequate in 25.8%
and antenatal care was adequate in 16.1%. In conclusion, direct
relationship was found between adequacy and quality of care
rendered to pregnant women and newborns, and fetal and infant
mortality. Moreover, our findings highlight that deaths could be
prevented by an adequate obstetric and neonatal management.