Abstract: Nowadays pharmaceutical care departments located in
hospitals are amongst the important pillars of the healthcare system.
The aim of this study was to evaluate quality of hospital drugstores
affiliated with Kermanshah University of Medical Sciences.
In this cross-sectional study a validated questionnaire was used.
The questionnaire was filled in by the one of the researchers in all
seventeen hospital drugstores located in the teaching and nonteaching
hospitals affiliated with Kermanshah University of Medical
Sciences. The results shows that in observed hospitals,24% of
pharmacy environments, 25% of pharmacy store and storage
conditions, 49% of storage procedure, 25% of ordering drugs and
supplies, 73% of receiving supplies (proper procedure are fallowed
for receiving supplies), 35% of receiving supplies (prompt action
taken if deterioration of drugs received is suspected), 23.35% of
drugs delivery to patients and finally 0% of stock cards are used for
proper inventory control have full compliance with standards.
Abstract: Titanium oxide films with different morphologies have for the first time been fabricated through hydrothermal reactions between a titanium substrate and iodine powder in water or ethanol. SEM revealed that iodine supported titanium (Ti-I2) surface shows different morphologies with variable treatment conditions. The mean surface roughness (Ra) was increased in the different groups. Use of surfactant has a role to increase the roughness of the film. The surface roughness was in the range of 0.15 μm-0.42 μm. Furthermore, the electrochemical examinations showed that the Ti-I2 surface fabricated in alcoholic medium has high corrosion resistance than in aqueous medium.
Abstract: Oxidative stress is considered to be the cause for onset
and the progression of type 2 diabetes mellitus (T2DM) and
complications including neuropathy. It is a deleterious process that
can be an important mediator of damage to cell structures: protein,
lipids and DNA. Data suggest that in patients with diabetes and
diabetic neuropathy DNA repair is impaired, which prevents effective
removal of lesions. Objective: The aim of our study was to evaluate
the association of the hOGG1 (326 Ser/Cys) and XRCC1 (194
Arg/Trp, 399 Arg/Gln) gene polymorphisms whose protein is
involved in the BER pathway with DNA repair efficiency in patients
with diabetes type 2 and diabetic neuropathy compared to the healthy
subjects. Genotypes were determined by PCR-RFLP analysis in 385
subjects, including 117 with type 2 diabetes, 56 with diabetic
neuropathy and 212 with normal glucose metabolism. The
polymorphisms studied include codon 326 of hOGG1 and 194, 399
of XRCC1 in the base excision repair (BER) genes. Comet assay was
carried out using peripheral blood lymphocytes from the patients and
controls. This test enabled the evaluation of DNA damage in cells
exposed to hydrogen peroxide alone and in the combination with the
endonuclease III (Nth). The results of the analysis of polymorphism
were statistically examination by calculating the odds ratio (OR) and
their 95% confidence intervals (95% CI) using the ¤ç2-tests. Our data
indicate that patients with diabetes mellitus type 2 (including those
with neuropathy) had higher frequencies of the XRCC1 399Arg/Gln
polymorphism in homozygote (GG) (OR: 1.85 [95% CI: 1.07-3.22],
P=0.3) and also increased frequency of 399Gln (G) allele (OR: 1.38
[95% CI: 1.03-1.83], P=0.3). No relation to other polymorphisms
with increased risk of diabetes or diabetic neuropathy. In T2DM
patients complicated by neuropathy, there was less efficient repair of
oxidative DNA damage induced by hydrogen peroxide in both the
presence and absence of the Nth enzyme. The results of our study
suggest that the XRCC1 399 Arg/Gln polymorphism is a significant
risk factor of T2DM in Polish population. Obtained data suggest a
decreased efficiency of DNA repair in cells from patients with
diabetes and neuropathy may be associated with oxidative stress.
Additionally, patients with neuropathy are characterized by even
greater sensitivity to oxidative damage than patients with diabetes,
which suggests participation of free radicals in the pathogenesis of
Abstract: Endovascular aneurysm repair is a new and minimally invasive repair for patients with abdominal aortic aneurysm (AAA). This method has potential advantages that are incomparable with other repair methods. However, the enlargement of aneurysm in the absence of endoleak, which is known as endotension, may occur as one of post-operative compliances of this method. Typically, endotension is mainly as a result of pressure transmitted to aneurysm sac by endovascular installed graft. After installation of graft the aneurysm sac reduces significantly but remains non-zero. There are some factors which affect this pressure transmitted. In this study, the geometry features of installed vascular graft have been considered. It is inferred that graft neck angle and iliac bifurcation angle are two factors which can affect the drag force on graft and consequently the pressure transmitted to aneurysm.
Abstract: The technological concepts such as wireless hospital
and portable cardiac telemetry system require the development of
physiological signal acquisition devices to be easily integrated into
the hospital database. In this paper we present the low cost, portable
wireless ECG acquisition hardware that transmits ECG signals to a
dedicated computer.The front end of the system obtains and
processes incoming signals, which are then transmitted via a
microcontroller and wireless Bluetooth module. A monitoring
purpose Bluetooth based end user application integrated with patient
database management module is developed for the computers. The
system will act as a continuous event recorder, which can be used to
follow up patients who have been resuscitatedfrom cardiac arrest,
ventricular tachycardia but also for diagnostic purposes for patients
with arrhythmia symptoms. In addition, cardiac information can be
saved into the patient-s database of the hospital.
Abstract: Life is beautiful. But, it is decided by genes, environment and the individual and shattered by the natural and / or the invited problems. Most of the global rural helpless masses are struggling for their survival since; they are neglected in all aspects of life including health. Amidst a countless number of miserable diseases in man, diabetes is becoming a dreaded killer and ramifying the entire globe in a jet speed. Diabetes control continues as a Herculean task to the scientific community and the modern society in the 21st century also. T2DM is not pertaining to any age and it can develop even during the childhood. This multifactorial disease abruptly changes the activities of certain vital biomarkers in the present rural T2DM cases. A remarkable variation in the levels of biomarkers like AST, ALT, GGT, ALP, LDH, HbA1C, C- peptide, fasting sugar, post-prandial sugar, sodium, potassium, BUN, creatinine and insulin show the rampant nature of T2DM in this physically active rural agrarian community.
Abstract: Finite element method was applied to model damage
development in the femoral neck during a sideways fall. The femoral
failure was simulated using the maximum principal strain criterion.
The evolution of damage was consistent with previous studies. It was
initiated by compressive failure at the junction of the superior aspect
of the femoral neck and the greater trochanter. It was followed by
tensile failure that occurred at the inferior aspect of the femoral neck
before a complete transcervical fracture was observed. The estimated
failure line was less than 50° from the horizontal plane (Pauwels type
Abstract: The purpose of this study was to analyze relationship
between gender, BMI, and lifestyle with bone mineral density
(BMD) of adolescent in urban areas . The place of this study in
Jakarta State University, Indonesia. The number of samples involved
as many as 200 people, consisting of 100 men and 100 women. BMD
was measured using Quantitative Ultrasound Bone Densitometry.
While the questionnaire used to collect data on age, gender, and
lifestyle (calcium intake, smoking habits, alcohol consumption, tea,
coffee, sports, and sun exposure). Mean age of men and women,
respectively as much as 20.7 ± 2.18 years and 21 ± 1.61 years. Mean
BMD values of men was 1.084 g/cm ² ± 0.11 while women was
0.976 g/cm ² ± 0.10. Men and women with normal BMD respectively
as much as 46.7% and 16.7%. Men and women affected by
osteopenia respectively as much as 50% and 80%. Men and women
affected by osteoporosis respectively as much as 3.3% and 3.3%.
Mean BMI of men and women, respectively as much as 21.4 ± 2.07
kg/m2 and 20.9 ± 2.06 kg/m2. Mean lifestyle score of men and
women , respectively as much as 71.9 ± 5.84 and 70.1 ± 5.67
(maximum score 100). Based on Spearman and Pearson Correlation
test, there were relationship significantly between gender and
lifestyle with BMD.
Abstract: The primary cause of Total Hip Replacement (THR)
failure for younger patients is aseptic loosening. This complication is
twice more likely to happen in acetabular cup than in femoral stem.
Excessive micromotion between bone and implant will cause
loosening and it depends in patient activities, age and bone. In this
project, the effects of different metal back design of press fit on
osseointegration of the acetabular cup are carried out. Commercial
acetabular cup designs, namely Spiked, Superfix and Quadrafix are
modelled and analyzed using commercial finite element software.
The diameter of acetabular cup is based on the diameter of acetabular
rim to make sure the component fit to the acetabular cavity. A new
design of acetabular cup are proposed and analyzed to get better
osseointegration between the bones and implant interface. Results
shows that the proposed acetabular cup designs are more stable
compared to other designs with respect to stress and displacement
Abstract: In this research, the diabetes conditions of people (healthy, prediabete and diabete) were tried to be identified with noninvasive palm perspiration measurements. Data clusters gathered from 200 subjects were used (1.Individual Attributes Cluster and 2. Palm Perspiration Attributes Cluster). To decrase the dimensions of these data clusters, Principal Component Analysis Method was used. Data clusters, prepared in that way, were classified with Support Vector Machines. Classifications with highest success were 82% for Glucose parameters and 84% for HbA1c parametres.