Abstract: The frontal area in the brain is known to be involved in
behavioral judgement. Because a Kanji character can be discriminated
visually and linguistically from other characters, in Kanji character
discrimination, we hypothesized that frontal event-related potential
(ERP) waveforms reflect two discrimination processes in separate
time periods: one based on visual analysis and the other based
on lexcical access. To examine this hypothesis, we recorded ERPs
while performing a Kanji lexical decision task. In this task, either a
known Kanji character, an unknown Kanji character or a symbol was
presented and the subject had to report if the presented character was
a known Kanji character for the subject or not. The same response
was required for unknown Kanji trials and symbol trials. As a preprocessing
of signals, we examined the performance of a method
using independent component analysis for artifact rejection and found
it was effective. Therefore we used it. In the ERP results, there
were two time periods in which the frontal ERP wavefoms were
significantly different betweeen the unknown Kanji trials and the
symbol trials: around 170ms and around 300ms after stimulus onset.
This result supported our hypothesis. In addition, the result suggests
that Kanji character lexical access may be fully completed by around
260ms after stimulus onset.
Abstract: The prevalence of non organic constipation differs
from country to country and the reliability of the estimate rates is
uncertain. Moreover, the clinical relevance of subdividing the
heterogeneous functional constipation disorders into pre-defined
subgroups is largely unknown.. Aim: to estimate the prevalence of
constipation in a population-based sample and determine whether
clinical subgroups can be identified. An age and gender stratified
sample population from 5 Italian cities was evaluated using a
previously validated questionnaire. Data mining by cluster analysis
was used to determine constipation subgroups. Results: 1,500
complete interviews were obtained from 2,083 contacted households
(72%). Self-reported constipation correlated poorly with symptombased
constipation found in 496 subjects (33.1%). Cluster analysis
identified four constipation subgroups which correlated to subgroups
identified according to pre-defined symptom criteria. Significant
differences in socio-demographics and lifestyle were observed
among subgroups.
Abstract: It is sometimes difficult to differentiate between
innocent murmurs and pathological murmurs during auscultation. In
these difficult cases, an intelligent stethoscope with decision support
abilities would be of great value. In this study, using a dog model,
phonocardiographic recordings were obtained from 27 boxer dogs
with various degrees of aortic stenosis (AS) severity. As a reference
for severity assessment, continuous wave Doppler was used. The data
were analyzed with recurrence quantification analysis (RQA) with
the aim to find features able to distinguish innocent murmurs from
murmurs caused by AS. Four out of eight investigated RQA features
showed significant differences between innocent murmurs and
pathological murmurs. Using a plain linear discriminant analysis
classifier, the best pair of features (recurrence rate and entropy)
resulted in a sensitivity of 90% and a specificity of 88%. In
conclusion, RQA provide valid features which can be used for
differentiation between innocent murmurs and murmurs caused by
AS.
Abstract: Numerous divergence measures (spectral distance, cepstral
distance, difference of the cepstral coefficients, Kullback-Leibler
divergence, distance given by the General Likelihood Ratio, distance
defined by the Recursive Bayesian Changepoint Detector and the
Mahalanobis measure) are compared in this study. The measures are
used for detection of abrupt spectral changes in synthetic AR signals
via the sliding window algorithm. Two experiments are performed;
the first is focused on detection of single boundary while the second
concentrates on detection of a couple of boundaries. Accuracy of
detection is judged for each method; the measures are compared
according to results of both experiments.
Abstract: With getting older in the whole population, the
prevalence of stroke and its residual disability is getting higher and
higher recently in Taiwan. The functional electrical stimulation
cycling system (FESCS) is useful for hemiplegic patients. Because
that the muscle of stroke patients is under hybrid activation. The raw
electromyography (EMG) represents the residual muscle force of
stroke subject whereas the peak-to-peak of stimulus EMG indicates the
force enhancement benefiting from ES. It seems that EMG signals
could be used for a parameter of feedback control mechanism. So, we
design the feedback control protocol of FESCS, it includes
physiological signal recorder, FPGA biomedical module, DAC and
electrical stimulation circuit. Using the intensity of real-time EMG
signal obtained from patients, as a feedback control method for the
output voltage of FES-cycling system.
Abstract: This paper aims at presenting the biotechnology used
to obtain collagen-based gels from shark (Squalus acanthias) and brill
skin, marine fish growing in the Black Sea. Due to the structure of its
micro-fibres, collagen can be considered a nanomaterial; in order to
use collagen-based matrixes as biomaterial, rheological studies must
be performed first, to state whether they are stable or not. For the
triple-helix structure to remain stable within these gels at room or
human body temperature, they must be stabilized by reticulation.