Abstract: In this work, we consider a deterministic model for
the transmission of leptospirosis which is currently spreading in the
Thai population. The SIR model which incorporates the features of
this disease is applied to the epidemiological data in Thailand. It is
seen that the numerical solutions of the SIR equations are in good
agreement with real empirical data. Further improvements are
discussed.
Abstract: A number of previous studies were rarely considered
the effects of transient non-uniform balloon expansion on evaluation
of the properties and behaviors of stents during stent expansion, nor
did they determine parameters to maximize the performances driven
by mechanical characteristics. Therefore, in order to fully understand
the mechanical characteristics and behaviors of stent, it is necessary to
consider a realistic modeling of transient non-uniform balloon-stent
expansion. The aim of the study is to propose design parameters
capable of improving the ability of vascular stent through a
comparative study of seven commercial stents using finite element
analyses of a realistic transient non-uniform balloon-stent expansion
process. In this study, seven representative commercialized stents were
evaluated by finite element (FE) analysis in terms of the criteria based
on the itemized list of Food and Drug Administration (FDA) and
European Standards (prEN). The results indicate that using stents
composed of opened unit cells connected by bend-shaped link
structures and controlling the geometrical and morphological features
of the unit cell strut or the link structure at the distal ends of stent may
improve mechanical characteristics of stent. This study provides a
better method at the realistic transient non-uniform balloon-stent
expansion by investigating the characteristics, behaviors, and
parameters capable of improving the ability of vascular stent.
Abstract: Semiconductor nanomaterials like TiO2 nanoparticles
(TiO2-NPs) approximately less than 100 nm in diameter have become
a new generation of advanced materials due to their novel and
interesting optical, dielectric, and photo-catalytic properties. With the
increasing use of NPs in commerce, to date few studies have
investigated the toxicological and environmental effects of NPs.
Motivated by the importance of TiO2-NPs that may contribute to the
cancer research field especially from the treatment prospective
together with the fractal analysis technique, we have investigated the
effect of TiO2-NPs on colony morphology in the dark condition
using fractal dimension as a key morphological characterization
parameter. The aim of this work is mainly to investigate the cytotoxic
effects of TiO2-NPs in the dark on the growth of human cervical
carcinoma (HeLa) cell colonies from morphological aspect. The in
vitro studies were carried out together with the image processing
technique and fractal analysis. It was found that, these colonies were
abnormal in shape and size. Moreover, the size of the control
colonies appeared to be larger than those of the treated group. The
mean Df +/- SEM of the colonies in untreated cultures was
1.085±0.019, N= 25, while that of the cultures treated with TiO2-NPs
was 1.287±0.045. It was found that the circularity of the control
group (0.401±0.071) is higher than that of the treated group
(0.103±0.042). The same tendency was found in the diameter
parameters which are 1161.30±219.56 μm and 852.28±206.50 μm
for the control and treated group respectively. Possible explanation of
the results was discussed, though more works need to be done in
terms of the for mechanism aspects. Finally, our results indicate that
fractal dimension can serve as a useful feature, by itself or in
conjunction with other shape features, in the classification of cancer
colonies.
Abstract: Clusters of microcalcifications in mammograms are an
important sign of breast cancer. This paper presents a complete
Computer Aided Detection (CAD) scheme for automatic detection of
clustered microcalcifications in digital mammograms. The proposed
system, MammoScan μCaD, consists of three main steps. Firstly
all potential microcalcifications are detected using a a method for
feature extraction, VarMet, and adaptive thresholding. This will also
give a number of false detections. The goal of the second step,
Classifier level 1, is to remove everything but microcalcifications.
The last step, Classifier level 2, uses learned dictionaries and sparse
representations as a texture classification technique to distinguish
single, benign microcalcifications from clustered microcalcifications,
in addition to remove some remaining false detections. The system
is trained and tested on true digital data from Stavanger University
Hospital, and the results are evaluated by radiologists. The overall
results are promising, with a sensitivity > 90 % and a low false
detection rate (approx 1 unwanted pr. image, or 0.3 false pr. image).
Abstract: Advances in clinical medical imaging have brought about the routine production of vast numbers of medical images that need to be analyzed. As a result an enormous amount of computer vision research effort has been targeted at achieving automated medical image analysis. Computed Tomography (CT) is highly accurate for diagnosing liver tumors. This study aimed to evaluate the potential role of the wavelet and the neural network in the differential diagnosis of liver tumors in CT images. The tumors considered in this study are hepatocellular carcinoma, cholangio carcinoma, hemangeoma and hepatoadenoma. Each suspicious tumor region was automatically extracted from the CT abdominal images and the textural information obtained was used to train the Probabilistic Neural Network (PNN) to classify the tumors. Results obtained were evaluated with the help of radiologists. The system differentiates the tumor with relatively high accuracy and is therefore clinically useful.
Abstract: This paper proposes a method for speckle reduction in
medical ultrasound imaging while preserving the edges with the
added advantages of adaptive noise filtering and speed. A nonlinear
image diffusion method that incorporates local image parameter,
namely, scatterer density in addition to gradient, to weight the
nonlinear diffusion process, is proposed. The method was tested for
the isotropic case with a contrast detail phantom and varieties of
clinical ultrasound images, and then compared to linear and some
other diffusion enhancement methods. Different diffusion parameters
were tested and tuned to best reduce speckle noise and preserve
edges. The method showed superior performance measured both
quantitatively and qualitatively when incorporating scatterer density
into the diffusivity function. The proposed filter can be used as a
preprocessing step for ultrasound image enhancement before
applying automatic segmentation, automatic volumetric calculations,
or 3D ultrasound volume rendering.